{"id":12479,"date":"2026-06-17T21:02:22","date_gmt":"2026-06-17T12:02:22","guid":{"rendered":"https:\/\/readtrends.com\/ko\/capsaicin-nrf2-gastric-protection\/"},"modified":"2026-06-17T21:02:22","modified_gmt":"2026-06-17T12:02:22","slug":"capsaicin-nrf2-gastric-protection","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/capsaicin-nrf2-gastric-protection\/","title":{"rendered":"\u201c\ub9e4\uc6b4\ub9db\uc758 \ubc18\uc804\u201d\u2026 \ucea1\uc0ac\uc774\uc2e0, \uc54c\ucf54\uc62c\uc131 \uc704 \uc190\uc0c1 \uc904\uc778\ub2e4?"},"content":{"rendered":"<article>\n<p><strong>\ud575\uc2ec \uc694\uc57d<\/strong><\/p>\n<p>\uc911\uad6d \ud188\uc9c4\ub300\ud559\uad50 \uc5f0\uad6c\uc9c4\uc740 \ub9e4\uc6b4\ub9db \uc131\ubd84\uc778 \ucea1\uc0ac\uc774\uc2e0\uc774 \uc54c\ucf54\uc62c(\uc5d0\ud0c4\uc62c)\ub85c \uc720\ubc1c\ub41c \uc704 \uc810\ub9c9 \uc190\uc0c1\uc744 \uc5b5\uc81c\ud55c\ub2e4\uace0 \ubcf4\uace0\ud588\ub2e4. \uc5f0\uad6c\ub294 \uc0ac\ub78c \uc704 \uc810\ub9c9 \uc0c1\ud53c\uc138\ud3ec\uc640 \uc950(\ub9c8\uc6b0\uc2a4) \ubaa8\ub378\uc744 \ud65c\uc6a9\ud588\uc73c\uba70, \ucea1\uc0ac\uc774\uc2e0\uc744 \ub098\ub178\uc785\uc790 \ud615\ud0dc\ub85c \ud22c\uc5ec\ud55c \ub4a4 \uace0\ub18d\ub3c4 \uc54c\ucf54\uc62c\uc5d0 \ub178\ucd9c\uc2dc\ucf1c \ud6a8\uacfc\ub97c \ube44\uad50\ud588\ub2e4. \uc2e4\ud5d8 \uacb0\uacfc \uc54c\ucf54\uc62c \ub2e8\ub3c5 \ub178\ucd9c\uad70\uc758 \uc704\uada4\uc591 \uc9c0\uc218\ub294 36.0\uae4c\uc9c0 \uc0c1\uc2b9\ud55c \ubc18\uba74, \ucea1\uc0ac\uc774\uc2e0 \uc804\ucc98\ub9ac\uad70\uc740 5.3\uc73c\ub85c \ub0ae\uc544\uc9c0\ub294 \ub4f1 \ub69c\ub837\ud55c \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubcf4\uc600\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774 \ud6a8\uacfc\uac00 \ud56d\uc0b0\ud654 \ud0d0\uc9c0\u00b7\uc870\uc808 \ub2e8\ubc31\uc9c8\uc778 NRF2\uc758 \ud65c\uc131\ud654(KEAP1-NRF2 \uc0c1\ud638\uc791\uc6a9\uc758 \uc5b5\uc81c)\ub97c \ud1b5\ud574 \ub098\ud0c0\ub09c\ub2e4\uace0 \ud574\uc11d\ud588\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c \uc8fc\uccb4: \uc911\uad6d \ud188\uc9c4\ub300\ud559\uad50 \uc5f0\uad6c\ud300\uc774 \uc0ac\ub78c \uc704 \uc810\ub9c9 \uc0c1\ud53c\uc138\ud3ec(in vitro)\uc640 \uc950(in vivo) \ubaa8\ub378\uc744 \uc0ac\uc6a9\ud574 \uc2e4\ud5d8\uc744 \uc218\ud589\ud588\ub2e4.<\/li>\n<li>\ud22c\uc5ec \ubc29\uc2dd: \ucea1\uc0ac\uc774\uc2e0\uc744 \ub098\ub178\uc785\uc790 \ud615\ud0dc\ub85c \uc81c\uc870\ud574 \ud761\uc218\uc728\uacfc \uc804\ub2ec \ud6a8\uc728\uc744 \ub192\uc778 \ub4a4 \uc2e4\ud5d8\ub3d9\ubb3c\uc5d0 \ud22c\uc5ec\ud588\ub2e4.<\/li>\n<li>\uc2e4\ud5d8 \uc870\uac74: \uc950\ub97c 24\uc2dc\uac04 \uae08\uc2dd\uc2dc\ud0a8 \ub4a4 \uc77c\ubd80\uc5d0 \ucea1\uc0ac\uc774\uc2e0 \ub098\ub178\uc785\uc790\ub97c \ud22c\uc5ec\ud558\uace0, 45\ubd84 \ud6c4 \uace0\ub18d\ub3c4 \uc5d0\ud0c4\uc62c\uc744 \ud22c\uc5ec\ud574 \uc704 \uc190\uc0c1\uc744 \uc720\ubc1c\ud588\ub2e4.<\/li>\n<li>\uc8fc\uc694 \uacb0\uacfc(\uada4\uc591 \uc9c0\uc218): \uc5d0\ud0c4\uc62c \ub2e8\ub3c5 \ub178\ucd9c\uad70\uc758 \uc704\uada4\uc591 \uc9c0\uc218\ub294 36.0, \ucea1\uc0ac\uc774\uc2e0 \uc804\ucc98\ub9ac\uad70\uc740 5.3\uc73c\ub85c \ubcf4\uace0\ub3fc \ud070 \ucc28\uc774\ub97c \ubcf4\uc600\ub2e4.<\/li>\n<li>\uc138\ud3ec \uc218\uc900 \uc601\ud5a5: \ud65c\uc131\uc0b0\uc18c(ROS) \uc0dd\uc131\uc740 \uc57d 37% \uac10\uc18c\ud588\uace0, \uc9c0\uc9c8 \uacfc\uc0b0\ud654(\uc138\ud3ec\ub9c9 \uc190\uc0c1 \uc9c0\ud45c)\ub294 \uc57d 73% \uc5b5\uc81c\ub410\ub2e4.<\/li>\n<li>\uc791\ub3d9 \uae30\uc804: \ucea1\uc0ac\uc774\uc2e0\uc774 KEAP1\uc758 \ud2b9\uc815 \ubd80\uc704\uc5d0 \uacb0\ud569\ud574 KEAP1-NRF2 \uacb0\ud569\uc744 \uc57d\ud654\uc2dc\ud0a4\uace0, \uc790\uc720\ub85c\uc6cc\uc9c4 NRF2\uac00 \ud575\uc73c\ub85c \uc774\ub3d9\ud574 \ud56d\uc0b0\ud654 \uc720\uc804\uc790\ub97c \ud65c\uc131\ud654\uc2dc\ud0a8\ub2e4.<\/li>\n<li>\ud559\uc220 \uac8c\uc7ac: \ud574\ub2f9 \uc5f0\uad6c\ub294 2026\ub144 4\uc6d4 \uad6d\uc81c \ud559\uc220\uc9c0 eLife\uc5d0 \uac8c\uc7ac\ub418\uc5c8\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\uc704 \uc810\ub9c9\uc740 \uc54c\ucf54\uc62c, \uc57d\ubb3c, \uac10\uc5fc \ub4f1 \uc5ec\ub7ec \uc2a4\ud2b8\ub808\uc2a4 \uc694\uc778\uc5d0 \uc758\ud574 \uc27d\uac8c \uc190\uc0c1\ub420 \uc218 \uc788\ub2e4. \ud2b9\ud788 \uc5d0\ud0c4\uc62c\uc740 \uc704 \uc810\ub9c9 \uc138\ud3ec\uc5d0 \uc9c1\uc811\uc801\uc778 \uc0b0\ud654\uc801 \uc190\uc0c1\uc744 \uc720\ubc1c\ud574 \ucd9c\ud608\uacfc \uada4\uc591\uc744 \ucd08\ub798\ud558\uba70, \uae09\uc131 \uc704\uc7a5 \uc190\uc0c1 \ubaa8\ub378\uc5d0\uc11c \ub110\ub9ac \uc0ac\uc6a9\ub41c\ub2e4. \uc778\uccb4\uc5d0\uc11c\uc758 \uc190\uc0c1 \ubc29\uc9c0\ub97c \uc704\ud574 \ud56d\uc0b0\ud654 \ubc29\uc5b4 \uc2dc\uc2a4\ud15c\uc774 \uc911\uc694\ud558\uba70, \uadf8 \uac00\uc6b4\ub370 NRF2 \uacbd\ub85c\ub294 \ud575\uc2ec\uc801\uc778 \ubcf4\ud638 \uc5ed\ud560\uc744 \uc218\ud589\ud55c\ub2e4.<\/p>\n<p>NRF2\ub294 \ud3c9\uc0c1\uc2dc KEAP1\uc5d0 \uc758\ud574 \uc138\ud3ec\uc9c8\uc5d0\uc11c \uc5b5\uc81c\ub418\uace0 \ubd84\ud574\ub418\uc9c0\ub9cc, \uc0b0\ud654\uc801 \uc2a4\ud2b8\ub808\uc2a4\ub098 \ud2b9\uc815 \ud654\ud569\ubb3c\uc5d0 \uc758\ud574 KEAP1-NRF2 \uacb0\ud569\uc774 \ud574\uc81c\ub418\uba74 NRF2\uac00 \ud575\uc73c\ub85c \uc774\ub3d9\ud574 \ud56d\uc0b0\ud654\u00b7\ud574\ub3c5 \uc720\uc804\uc790\ub97c \ubc1c\ud604\uc2dc\ud0a8\ub2e4. \uc774\uc5d0 \ub530\ub77c NRF2\ub97c \ud45c\uc801\ud654\ud55c \uc57d\ubb3c \uac1c\ubc1c\uc740 \ub178\ud654, \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658, \uc2ec\ud608\uad00 \uc9c8\ud658 \ub4f1 \uad11\ubc94\uc704\ud55c \ubd84\uc57c\uc758 \uc5f0\uad6c \uc8fc\uc81c\uac00 \ub410\ub2e4.<\/p>\n<p>\ucea1\uc0ac\uc774\uc2e0\uc740 \uc804\ud1b5\uc801\uc73c\ub85c \ud1b5\uac01\u00b7\uc18c\ud654\uacc4 \uc790\uadf9 \ubb3c\uc9c8\ub85c \uc54c\ub824\uc838 \uc654\uc9c0\ub9cc, \ucd5c\uadfc\uc5d0\ub294 \ud56d\uc5fc\u00b7\ud56d\uc0b0\ud654 \uc791\uc6a9\uc774 \ubcf4\uace0\ub418\uace0 \uc788\ub2e4. \ub2e4\ub9cc \uae30\uc874 \uc5f0\uad6c\ub4e4\uc740 \ubaa8\ub378\uacfc \uc870\uac74\uc774 \ub2e4\uc591\ud574 \uc77c\uad00\ub41c \uae30\uc804 \uaddc\uba85\uc774 \ubd80\uc871\ud588\ub294\ub370, \uc774\ubc88 \uc5f0\uad6c\ub294 \ucea1\uc0ac\uc774\uc2e0\uc774 KEAP1-NRF2 \uc0c1\ud638\uc791\uc6a9\uc744 \uc9c1\uc811 \ubc29\ud574\ud558\ub294 \ubd84\uc790\uc801 \uadfc\uac70\ub97c \uc81c\uc2dc\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ubbf8\uac00 \uc788\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\ud300\uc740 \uba3c\uc800 \uc778\uac04 \uc704 \uc810\ub9c9 \uc0c1\ud53c\uc138\ud3ec\ub97c \uc774\uc6a9\ud55c \uc138\ud3ec \uc2e4\ud5d8\uc5d0\uc11c \ucea1\uc0ac\uc774\uc2e0 \ucc98\ub9ac \uc2dc \ud65c\uc131\uc0b0\uc18c \uc0dd\uc131\uacfc \uc9c0\uc9c8 \uacfc\uc0b0\ud654\uac00 \uc720\uc758\ud558\uac8c \uc5b5\uc81c\ub418\ub294 \uac83\uc744 \ud655\uc778\ud588\ub2e4. \uc774\uc5b4 \uc950 \ubaa8\ub378\uc5d0\uc11c\ub294 \ucea1\uc0ac\uc774\uc2e0\uc744 \ub098\ub178\uc785\uc790\ub85c \uc81c\uc870\ud574 \uccb4\ub0b4 \uc804\ub2ec \ud6a8\uc728\uc744 \ub192\uc778 \ud6c4, \uae08\uc2dd \uc0c1\ud0dc\uc5d0\uc11c 45\ubd84 \ub4a4 \uc5d0\ud0c4\uc62c\uc744 \ud22c\uc5ec\ud574 \uc704 \uc190\uc0c1 \uc815\ub3c4\ub97c \ube44\uad50\ud588\ub2e4.<\/p>\n<p>\uc870\uc9c1\ud559\uc801 \ubd84\uc11d\uc5d0\uc11c \uc5d0\ud0c4\uc62c \ub2e8\ub3c5 \ub178\ucd9c\uad70\uc740 \ucd9c\ud608\u00b7\uad34\uc0ac\u00b7\uada4\uc591\uc744 \ud3ec\ud568\ud55c \uc2ec\uac01\ud55c \uc810\ub9c9 \uc190\uc0c1\uc774 \uad00\ucc30\ub41c \ubc18\uba74, \ucea1\uc0ac\uc774\uc2e0 \uc804\ucc98\ub9ac\uad70\uc740 \uc810\ub9c9 \ubcf4\uc874\uc774 \ub69c\ub837\ud588\uace0 \uada4\uc591 \uc9c0\uc218\uac00 36.0\uc5d0\uc11c 5.3\uc73c\ub85c \ud06c\uac8c \ub0ae\uc544\uc84c\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774\ub7ec\ud55c \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc138\ud3ec \uc218\uc900\uc758 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uac10\uc18c\uc640 \uc77c\uce58\ud55c\ub2e4\uace0 \ubcf4\uace0\ud588\ub2e4.<\/p>\n<p>\ubd84\uc790\uc801 \ubd84\uc11d\uc5d0\uc11c\ub294 \ucea1\uc0ac\uc774\uc2e0\uc774 KEAP1\uc758 \ud2b9\uc815 \uacb0\ud569 \ubd80\uc704\uc5d0 \uc790\ub9ac\ud574 KEAP1-NRF2 \uacb0\ud569\uc744 \ubc29\ud574\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \uadf8 \uacb0\uacfc NRF2\uac00 \uc138\ud3ec\ud575\uc73c\ub85c \uc774\ub3d9\ud574 \ud56d\uc0b0\ud654 \ubc29\uc5b4 \uc720\uc804\uc790\ub4e4\uc744 \ubc1c\ud604\uc2dc\ud0a4\uba74\uc11c, \uc138\ud3ec \uc218\uc900\uc758 \ud56d\uc0b0\ud654 \ub2a5\ub825\uc774 \uc0c1\uc2b9\ud55c \uac83\uc73c\ub85c \ud574\uc11d\ud588\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uccab\uc9f8, \uc774 \uc5f0\uad6c\ub294 \ucea1\uc0ac\uc774\uc2e0\uc774 \ub2e8\uc21c\ud55c \uad6d\uc18c \uc790\uadf9 \ubb3c\uc9c8\uc744 \ub118\uc5b4 NRF2\ub97c \ub9e4\uac1c\ub85c \ud55c \ud56d\uc0b0\ud654 \ubc29\uc5b4\ub97c \ucd09\uc9c4\ud55c\ub2e4\ub294 \ubd84\uc790\uc801 \uadfc\uac70\ub97c \uc81c\uc2dc\ud55c\ub2e4. KEAP1-NRF2 \uc0c1\ud638\uc791\uc6a9\uc744 \uc9c1\uc811 \ud45c\uc801\ud558\ub294 \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc774\ub77c\ub294 \uc810\uc740 \uc57d\ubb3c \uac1c\ubc1c \uad00\uc810\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uac00\ub2a5\uc131\uc744 \uc5f4\uc5b4\uc900\ub2e4.<\/p>\n<p>\ub458\uc9f8, \ub3d9\ubb3c \ubaa8\ub378\uacfc \uc138\ud3ec \uc2e4\ud5d8\uc5d0\uc11c \uad00\ucc30\ub41c \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc784\uc0c1\uc801 \uc774\ub4dd\uc73c\ub85c \uc9c1\uacb0\ub418\ub824\uba74 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4. \uc950\uc5d0\uc11c \uc0ac\uc6a9\ud55c \ud22c\uc5ec \ubc29\uc2dd(\ub098\ub178\uc785\uc790), \uc6a9\ub7c9, \ud22c\uc5ec \uc2dc\uac04\uacfc \uc778\uac04\uc758 \uc12d\ucde8 \ubc29\uc2dd \ubc0f \uc548\uc804\uc131\uc740 \ub2e4\ub97c \uc218 \uc788\uc73c\uba70, \ub3c5\uc131\u00b7\ub300\uc0ac\u00b7\uc7a5\uae30 \uc548\uc804\uc131\uc5d0 \uad00\ud55c \uccb4\uacc4\uc801 \ud3c9\uac00\uac00 \uc120\ud589\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n<p>\uc14b\uc9f8, NRF2 \ud65c\uc131\ud654\ub294 \ub178\ud654, \uc554, \ud1f4\ud589\uc131 \uc9c8\ud658 \ub4f1 \uad11\ubc94\uc704\ud55c \ubcd1\ub9ac\uc5d0\uc11c \uc720\ub9ac\ud558\uac8c \uc791\uc6a9\ud560 \uc218 \uc788\uc9c0\ub9cc, \ub9cc\uc131\uc801\u00b7\uacfc\ub3c4\ud55c \ud65c\uc131\ud654\ub294 \uc554\uc138\ud3ec\uc758 \ud56d\uc0b0\ud654 \ubc29\uc5b4\ub97c \ub3d5\ub294 \ub4f1 \uc774\uc911\uc801 \ud6a8\uacfc\ub97c \uac00\uc9c8 \uc218 \uc788\ub2e4. \ub530\ub77c\uc11c \uc784\uc0c1 \uc801\uc6a9\uc744 \uc704\ud55c \uc57d\ubb3c\ud654 \uacfc\uc815\uc5d0\uc11c\ub294 \ud45c\uc801 \ud2b9\uc774\uc131\u00b7\uc6a9\ub7c9 \ubc18\uc751\uc131\u00b7\uc7a5\uae30 \uc601\ud5a5 \ud3c9\uac00\uac00 \uc911\uc694\ud558\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\uc9c0\ud45c<\/th>\n<th>\uc5d0\ud0c4\uc62c \ub2e8\ub3c5<\/th>\n<th>\ucea1\uc0ac\uc774\uc2e0 \uc804\ucc98\ub9ac<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\uc704\uada4\uc591 \uc9c0\uc218<\/td>\n<td>36.0<\/td>\n<td>5.3<\/td>\n<\/tr>\n<tr>\n<td>\ud65c\uc131\uc0b0\uc18c(ROS) \uc0dd\uc131<\/td>\n<td>\uae30\uc900\uce58 \ub300\ube44<\/td>\n<td>\uc57d 37% \uac10\uc18c<\/td>\n<\/tr>\n<tr>\n<td>\uc9c0\uc9c8 \uacfc\uc0b0\ud654(\uc138\ud3ec\ub9c9 \uc190\uc0c1)<\/td>\n<td>\uae30\uc900\uce58 \ub300\ube44<\/td>\n<td>\uc57d 73% \uc5b5\uc81c<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \ub17c\ubb38\uc5d0 \ubcf4\uace0\ub41c \uc8fc\uc694 \uc218\uce58\ub97c \ub2e8\uc21c \ube44\uad50\ud55c \uac83\uc774\ub2e4. \uc2e4\ud5d8\uad70\ubcc4 \ud45c\ubcf8\uc218, \ud1b5\uacc4\uc801 \uc720\uc758\uc131(p\uac12) \ub4f1 \uc0c1\uc138 \uc218\uce58\uc640 \uc2e4\ud5d8 \uc870\uac74\uc740 \uc6d0\ubb38\uc744 \ud1b5\ud574 \ud655\uc778\ud560 \ud544\uc694\uac00 \uc788\ub2e4. \ud2b9\ud788 \ub3d9\ubb3c \uc5f0\uad6c\uc758 \uc9c0\ud45c\ub294 \uc2e4\ud5d8 \uc124\uc815(\ud22c\uc5ec \uc6a9\ub7c9, \uc2dc\uac04 \ub4f1)\uc5d0 \ubbfc\uac10\ud558\ubbc0\ub85c \uc9c1\uc811 \ube44\uad50 \uc2dc \uc8fc\uc758\uac00 \ud544\uc694\ud558\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c\ud300\uc740 \ub17c\ubb38\uacfc \ubcf4\ub3c4\uc790\ub8cc\ub97c \ud1b5\ud574 \ucea1\uc0ac\uc774\uc2e0\uc758 \ubd84\uc790\uc801 \uc791\ub3d9\uae30\uc804\uc744 \uac15\uc870\ud588\ub2e4. \uad50\uc2e0\uc800\uc790 \uc785\uc7a5\uc744 \uc778\uc6a9\ud558\uba74 \ub2e4\uc74c\uacfc \uac19\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\ucea1\uc0ac\uc774\uc2e0\uc740 KEAP1\uacfc NRF2\uc758 \uc0c1\ud638\uc791\uc6a9\uc744 \uc9c1\uc811 \uc5b5\uc81c\ud558\ub294 \ucd5c\ucd08\uc758 \ucc9c\uc5f0 \ubb3c\uc9c8\uc774 \ub420 \uc218 \uc788\ub2e4.&#8221;<\/p>\n<p><cite>\uac15 \uc900 \uad50\uc218(\ud188\uc9c4\ub300\ud559\uad50, \uad50\uc2e0\uc800\uc790)<\/cite><\/p><\/blockquote>\n<p>\ud559\uacc4\uc640 \uc784\uc0c1\uacc4\uc5d0\uc11c\ub294 \ub300\uccb4\ub85c \uae30\ub300\uc640 \uc2e0\uc911\ud568\uc774 \uacf5\uc874\ud55c\ub2e4. \ud55c \uc18c\ud654\uae30\ub0b4\uacfc \uc804\ubb38\uac00\ub294 \uc774\ubc88 \uacb0\uacfc\uac00 \uae30\ucd08\uc5f0\uad6c\ub85c\uc11c\ub294 \uc758\ubbf8\uac00 \ud06c\uc9c0\ub9cc, \uc0ac\ub78c\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uc548\uc804\uc131\u00b7\uc720\ud6a8\uc131 \uac80\uc99d\uc774 \uc120\ud589\ub418\uc5b4\uc57c \ud55c\ub2e4\uace0 \uc9c0\uc801\ud588\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\ub3d9\ubb3c \ubc0f \uc138\ud3ec \uacb0\uacfc\ub294 \uace0\ubb34\uc801\uc774\uc9c0\ub9cc, \uc784\uc0c1 \uc801\uc6a9 \uc804\uc5d0\ub294 \uc6a9\ub7c9 \uc124\uc815\uacfc \uc548\uc804\uc131 \uc790\ub8cc\uac00 \ucda9\ubd84\ud788 \ucd95\uc801\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.&#8221;<\/p>\n<p><cite>\uad6d\ub0b4 \uc18c\ud654\uae30\ub0b4\uacfc \uc804\ubb38\uc758(\uc775\uba85 \uc694\uccad)<\/cite><\/p><\/blockquote>\n<h2>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>NRF2\ub294 \uc138\ud3ec \ub0b4 \ud56d\uc0b0\ud654 \ubc18\uc751\uc758 \ud575\uc2ec \uc804\uc0ac\uc778\uc790\ub85c, \ud65c\uc131\ud654\ub418\uba74 \ud56d\uc0b0\ud654\u00b7\ud574\ub3c5 \uc720\uc804\uc790\ub97c \ubc1c\ud604\uc2dc\ud0a8\ub2e4. KEAP1\uc740 NRF2\ub97c \uc5b5\uc81c\ud558\ub294 \ub2e8\ubc31\uc9c8\ub85c, KEAP1-NRF2 \uacb0\ud569\uc774 \ub04a\uae30\uba74 NRF2\uac00 \ud575\uc73c\ub85c \uc774\ub3d9\ud55c\ub2e4. \ub098\ub178\uc785\uc790\ub294 \uc57d\ubb3c\uc758 \uc0dd\uccb4\uc774\uc6a9\ub960\uacfc \ud45c\uc801 \uc804\ub2ec\uc744 \uac1c\uc120\ud558\uae30 \uc704\ud574 \uc0ac\uc6a9\ub418\ub294 \uc804\ub2ec\uccb4\ub85c, \uc57d\ubb3c\uc758 \ubd84\ud3ec\uc640 \ud761\uc218\ub97c \ubcc0\ud654\uc2dc\ud0ac \uc218 \uc788\ub2e4. \uc5d0\ud0c4\uc62c \uc720\ubc1c \uc704 \uc190\uc0c1 \ubaa8\ub378\uc740 \uae09\uc131 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \uc810\ub9c9 \uc190\uc0c1\uc744 \uc7ac\ud604\ud558\uae30 \uc704\ud574 \ub110\ub9ac \uc4f0\uc774\uba70, \uada4\uc591 \uc9c0\uc218\ub294 \uc870\uc9c1\ud559\uc801 \uc190\uc0c1 \uc815\ub3c4\ub97c \uc218\uce58\ud654\ud55c \uc9c0\ud45c\uc774\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<\/h2>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\uc778\uccb4 \uc801\uc6a9 \uac00\ub2a5\uc131: \uc950 \ubaa8\ub378\uc5d0\uc11c \uad00\ucc30\ub41c \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc778\uac04 \uc784\uc0c1\uc5d0\uc11c \ub3d9\uc77c\ud558\uac8c \uc7ac\ud604\ub420\uc9c0\ub294 \ubd88\ud655\uc2e4\ud558\ub2e4.<\/li>\n<li>\ud22c\uc5ec \ubc29\uc2dd\uacfc \uc6a9\ub7c9: \ub098\ub178\uc785\uc790 \ud615\ud0dc\uc758 \ucd5c\uc801 \uc6a9\ub7c9\u00b7\ud22c\uc5ec \uacbd\ub85c\uc640 \uc7a5\uae30 \uc548\uc804\uc131 \ub370\uc774\ud130\uac00 \ubd80\uc871\ud558\ub2e4.<\/li>\n<li>\uc7a5\uae30 \uc601\ud5a5: \uc7a5\uae30\uc801 NRF2 \ud65c\uc131\ud654\uc758 \uc774\uc911\uc801 \uc601\ud5a5(\uc608: \uc77c\ubd80 \uc554\uc5d0\uc11c\uc758 \ubcf4\ud638 \ud6a8\uacfc \uc5ed\ud589 \uac00\ub2a5\uc131)\uc5d0 \ub300\ud55c \ubd88\ud655\uc2e4\uc131\uc774 \ub0a8\uc544 \uc788\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ucea1\uc0ac\uc774\uc2e0\uc774 KEAP1-NRF2 \uc0c1\ud638\uc791\uc6a9\uc744 \uc57d\ud654\uc2dc\ucf1c NRF2\ub97c \ud65c\uc131\ud654\ud568\uc73c\ub85c\uc368 \uc54c\ucf54\uc62c \uc720\ubc1c \uc704 \uc810\ub9c9 \uc190\uc0c1\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\ub2e4\ub294 \ubd84\uc790\uc801 \uadfc\uac70\ub97c \uc81c\uc2dc\ud588\ub2e4. \ub3d9\ubb3c \ubc0f \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \uad00\ucc30\ub41c \uc218\uce58(\uada4\uc591 \uc9c0\uc218 36.0\u21925.3, ROS \uc57d 37% \uac10\uc18c, \uc9c0\uc9c8 \uacfc\uc0b0\ud654 \uc57d 73% \uc5b5\uc81c)\ub294 \ubcf4\ud638 \ud6a8\uacfc\uc758 \uaddc\ubaa8\ub97c \ubcf4\uc5ec\uc900\ub2e4.<\/p>\n<p>\ub2e4\ub9cc \uc784\uc0c1\uc801 \ud65c\uc6a9\uc744 \uc704\ud574\uc11c\ub294 \uc778\uccb4 \ub0b4 \uc57d\ub3d9\ud559\u00b7\uc548\uc804\uc131\u00b7\ud6a8\ub2a5 \uac80\uc99d\uc774 \ud544\uc694\ud558\uba70, \uc81c\ud488\ud654 \ub2e8\uacc4\uc5d0\uc11c\ub294 \ud22c\uc5ec \ud615\ud0dc(\ub098\ub178\uc785\uc790 \ud3ec\ud568)\uc640 \uc7a5\uae30 \uc601\ud5a5\uc5d0 \ub300\ud55c \ucca0\uc800\ud55c \uac80\ud1a0\uac00 \ud544\uc218\uc801\uc774\ub2e4. \ud5a5\ud6c4 \uc5f0\uad6c\ub294 \uc0ac\ub78c \ub300\uc0c1 \uc784\uc0c1\uc2dc\ud5d8\uacfc \ub2e4\uc591\ud55c \uc9c8\ud658 \ubaa8\ub378\uc5d0\uc11c\uc758 \uc7ac\ud604\uc131 \ud3c9\uac00\uc5d0 \ucd08\uc810\uc744 \ub9de\ucdb0\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"https:\/\/news.hidoc.co.kr\/news\/articleView.html?idxno=63748\" target=\"_blank\" rel=\"noopener\">\uc758\ud559\uc804\ubb38\ub9e4\uccb4 \ud558\uc774\ub2e5(\uc5b8\ub860 \ubcf4\ub3c4)<\/a><\/li>\n<li><a href=\"https:\/\/elifesciences.org\/\" target=\"_blank\" rel=\"noopener\">eLife(\ud559\uc220\uc9c0, 2026\ub144 4\uc6d4 \uac8c\uc7ac \ubcf4\uace0)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \uc911\uad6d \ud188\uc9c4\ub300\ud559\uad50 \uc5f0\uad6c\uc9c4\uc740 \ub9e4\uc6b4\ub9db \uc131\ubd84\uc778 \ucea1\uc0ac\uc774\uc2e0\uc774 \uc54c\ucf54\uc62c(\uc5d0\ud0c4\uc62c)\ub85c \uc720\ubc1c\ub41c \uc704 \uc810\ub9c9 \uc190\uc0c1\uc744 \uc5b5\uc81c\ud55c\ub2e4\uace0 \ubcf4\uace0\ud588\ub2e4. \uc5f0\uad6c\ub294 \uc0ac\ub78c \uc704 \uc810\ub9c9 \uc0c1\ud53c\uc138\ud3ec\uc640 \uc950(\ub9c8\uc6b0\uc2a4) \ubaa8\ub378\uc744 \ud65c\uc6a9\ud588\uc73c\uba70, \ucea1\uc0ac\uc774\uc2e0\uc744 \ub098\ub178\uc785\uc790 \ud615\ud0dc\ub85c \ud22c\uc5ec\ud55c \ub4a4 \uace0\ub18d\ub3c4 \uc54c\ucf54\uc62c\uc5d0 \ub178\ucd9c\uc2dc\ucf1c \ud6a8\uacfc\ub97c \ube44\uad50\ud588\ub2e4. \uc2e4\ud5d8 \uacb0\uacfc \uc54c\ucf54\uc62c \ub2e8\ub3c5 \ub178\ucd9c\uad70\uc758 \uc704\uada4\uc591 \uc9c0\uc218\ub294 36.0\uae4c\uc9c0 \uc0c1\uc2b9\ud55c \ubc18\uba74, \ucea1\uc0ac\uc774\uc2e0 \uc804\ucc98\ub9ac\uad70\uc740 5.3\uc73c\ub85c \ub0ae\uc544\uc9c0\ub294 \ub4f1 \ub69c\ub837\ud55c \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubcf4\uc600\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774 \ud6a8\uacfc\uac00 &#8230; <a title=\"\u201c\ub9e4\uc6b4\ub9db\uc758 \ubc18\uc804\u201d\u2026 \ucea1\uc0ac\uc774\uc2e0, \uc54c\ucf54\uc62c\uc131 \uc704 \uc190\uc0c1 \uc904\uc778\ub2e4?\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/capsaicin-nrf2-gastric-protection\/\" aria-label=\"\u201c\ub9e4\uc6b4\ub9db\uc758 \ubc18\uc804\u201d\u2026 \ucea1\uc0ac\uc774\uc2e0, \uc54c\ucf54\uc62c\uc131 \uc704 \uc190\uc0c1 \uc904\uc778\ub2e4?\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":12478,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\u201c\ub9e4\uc6b4\ub9db\uc758 \ubc18\uc804\u201d\u2026 \ucea1\uc0ac\uc774\uc2e0, \uc54c\ucf54\uc62c\uc131 \uc704 \uc190\uc0c1 \uc904\uc778\ub2e4? - \ud558\uc774\ub2e5","rank_math_description":"\ud188\uc9c4\ub300 \uc5f0\uad6c\uc9c4\uc774 \uc0ac\ub78c \uc138\ud3ec\u00b7\uc950 \ubaa8\ub378\uc5d0\uc11c \ucea1\uc0ac\uc774\uc2e0 \ub098\ub178\uc785\uc790\uac00 \uc54c\ucf54\uc62c \uc720\ubc1c \uc704 \uc190\uc0c1\uc744 \uc5b5\uc81c\ud558\uace0 NRF2 \ud65c\uc131\ud654\ub97c \ud1b5\ud574 \ud56d\uc0b0\ud654 \ubc29\uc5b4\ub97c \ucd09\uc9c4\ud55c\ub2e4\uace0 \ubcf4\uace0\ud588\ub2e4. \uc784\uc0c1 \uc801\uc6a9 \uc2dc \uac80\uc99d \uacfc\uc81c\uac00 \ub0a8\uc544\uc788\ub2e4.","rank_math_focus_keyword":"\ucea1\uc0ac\uc774\uc2e0,NRF2,KEAP1,\uc704\uc810\ub9c9,\uc54c\ucf54\uc62c","footnotes":""},"categories":[2],"tags":[],"class_list":["post-12479","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/12479","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=12479"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/12479\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/12478"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=12479"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=12479"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=12479"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}