{"id":3997,"date":"2025-12-01T14:06:34","date_gmt":"2025-12-01T05:06:34","guid":{"rendered":"https:\/\/readtrends.com\/ko\/dgist-clpb-huntington-therapy\/"},"modified":"2025-12-01T14:06:34","modified_gmt":"2025-12-01T05:06:34","slug":"dgist-clpb-huntington-therapy","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/dgist-clpb-huntington-therapy\/","title":{"rendered":"DGIST \uc5f0\uad6c\ud300, \ud5cc\ud305\ud134\ubcd1 \ub4f1 \ud1f4\ud589\uc131 \ub1cc\uc9c8\ud658 \uce58\ub8cc \uc0c8 \ubc29\ud5a5 \uc81c\uc2dc"},"content":{"rendered":"<article>\n<h2>\ud575\uc2ec \uc694\uc57d<\/h2>\n<p>DGIST \ub1cc\uacfc\ud559\uacfc \uc5c4\uc9c0\uc6d0\u00b7\uace0\uc7ac\uc6d0 \uad50\uc218 \uc5f0\uad6c\ud300(\uc81c1\uc800\uc790 \uae40\ud604\ud638 \ubc15\uc0ac\ud6c4\uc5f0\uc218\uc5f0\uad6c\uc6d0)\uc774 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub2e8\ubc31\uc9c8 ClpB\uac00 \ud5cc\ud305\ud134\ubcd1\uc758 \ub3c5\uc131 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\ub97c \uc9c1\uc811 \ud480\uc5b4 \uc81c\uac70\ud558\uace0 \uc190\uc0c1\ub41c \uc2e0\uacbd\uc138\ud3ec \uae30\ub2a5\uc744 \ud68c\ubcf5\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \uc138\ud3ec\u00b7\uc0dd\uc950 \ubaa8\ub378\uc5d0\uc11c \uaddc\uba85\ud588\ub2e4. \uc774 \uc5f0\uad6c\ub294 \uad6d\uc81c \ud559\uc220\uc9c0 Theranostics\uc5d0 \uac8c\uc7ac\ub418\uc5c8\uc73c\uba70 \uacfc\ud559\uae30\uc220\uc815\ubcf4\ud1b5\uc2e0\ubd80\uc640 \ud55c\uad6d\uc5f0\uad6c\uc7ac\ub2e8\uc758 \uc9c0\uc6d0\uc744 \ubc1b\uc558\ub2e4. \uae30\uc874\uc758 &#8216;\uc751\uc9d1 \uc608\ubc29&#8217; \uc804\ub7b5\uc744 \ub118\uc5b4 \uc774\ubbf8 \ud615\uc131\ub41c \uc751\uc9d1\uccb4\ub97c \ubd84\ud574\ud558\ub294 \uce58\ub8cc \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud55c\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c\uc9c4: DGIST(\ub300\uad6c\uacbd\ubd81\uacfc\ud559\uae30\uc220\uc6d0) \ub1cc\uacfc\ud559\uacfc \uc5c4\uc9c0\uc6d0\u00b7\uace0\uc7ac\uc6d0 \uad50\uc218\ud300 \ubc0f \uc81c1\uc800\uc790 \uae40\ud604\ud638 \ubc15\uc0ac\ud6c4\uc5f0\uc218\uc5f0\uad6c\uc6d0.<\/li>\n<li>\uc8fc\uc694 \ub2e8\ubc31\uc9c8: \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub2e8\ubc31\uc9c8 ClpB\uac00 \ub3c5\uc131 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\ub97c \ud574\uccb4\ud558\ub294 \uae30\ub2a5\uc744 \uc138\uacc4 \ucd5c\ucd08\ub85c \uaddc\uba85.<\/li>\n<li>\ubaa8\ub378: \ud5cc\ud305\ud134\ubcd1 \uc720\ub798 \uc138\ud3ec\ubaa8\ub378\uacfc \uc0dd\uc950\ubaa8\ub378\uc5d0\uc11c ClpB \ubc1c\ud604\uc744 \uc870\uc808\ud574 \uae30\ub2a5\uc744 \ubd84\uc11d\ud568.<\/li>\n<li>\uc2e4\ud5d8 \uacb0\uacfc: ClpB \uacfc\ubc1c\ud604 \uc2dc \ub3cc\uc5f0\ubcc0\uc774 \ud5cc\ud305\ud2f4 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\uac00 \uac10\uc18c\ud558\uace0 \uc2e0\uacbd\uc138\ud3ec \uc190\uc0c1\uc774 \uc644\ud654\ub428\uc744 \ud655\uc778.<\/li>\n<li>\uc758\uc758: \ud5cc\ud305\ud134\ubcd1\ubfd0 \uc544\ub2c8\ub77c \uc54c\uce20\ud558\uc774\uba38\u00b7\ud30c\ud0a8\uc2a8\u00b7\ub8e8\uac8c\ub9ad\ubcd1(ALS) \ub4f1 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\ud615 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc5d0 \uc801\uc6a9 \uac00\ub2a5\uc131 \uc81c\uc2dc.<\/li>\n<li>\ud559\uc220 \uac8c\uc7ac: \uc5f0\uad6c \uacb0\uacfc\ub294 Theranostics\uc5d0 \ucd9c\ud310\ub418\uc5b4 \uad6d\uc81c\uc801\uc73c\ub85c \uac80\ud1a0\u00b7\uacf5\uac1c\ub428.<\/li>\n<li>\uc9c0\uc6d0: \uacfc\uae30\uc815\ud1b5\ubd80\u00b7\ud55c\uad6d\uc5f0\uad6c\uc7ac\ub2e8\uc758 \uc5ec\ub7ec \uc5f0\uad6c\uc9c0\uc6d0\uc0ac\uc5c5\uacfc \uc138\uc885\uacfc\ud559\ud3a0\ub85c\uc6b0\uc2ed\uc758 \uc9c0\uc6d0\uc744 \ubc1b\uc74c.<\/li>\n<li>\uc784\uc0c1\uc801 \uc758\ubbf8: \uc774\ubbf8 \ucd95\uc801\ub41c \ub2e8\ubc31\uc9c8 \ub369\uc5b4\ub9ac\ub97c &#8216;\uc9c1\uc811 \ubd84\ud574&#8217;\ud574 \uc190\uc0c1\ub41c \uc2e0\uacbd \uae30\ub2a5\uc744 \ud68c\ubcf5\ud560 \uc218 \uc788\ub2e4\ub294 \uc810\uc774 \ud575\uc2ec\uc801 \ubc1c\uacac.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\ud5cc\ud305\ud134\ubcd1\uc740 \uc0c1\uc5fc\uc0c9\uccb4 \uc6b0\uc131 \uc720\uc804 \uc9c8\ud658\uc73c\ub85c \ubd80\ubaa8\ub85c\ubd80\ud130 \uc790\uc2dd\uc5d0\uac8c 50%\uc758 \ud655\ub960\ub85c \uc720\uc804\ub41c\ub2e4. \ubc1c\ubcd1\ud558\uba74 \uae30\uc5b5\ub825 \uc800\ud558\uc640 \uc6b4\ub3d9\uc7a5\uc560\uac00 \uc11c\uc11c\ud788 \uc9c4\ud589\ub418\uc5b4 \uc77c\uc0c1\uc0dd\ud65c\uc5d0 \uc2ec\uac01\ud55c \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4. \ud604\uc7ac\uae4c\uc9c0\ub294 \uc9c8\ubcd1\uc758 \uc9c4\ud589\uc744 \ub9c9\uac70\ub098 \uc774\ubbf8 \ubc1c\uc0dd\ud55c \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uc744 \ub418\ub3cc\ub9ac\ub294 \ud655\ub9bd\ub41c \uce58\ub8cc\ubc95\uc774 \uc5c6\ub2e4. \uc774\uc5d0 \ub530\ub77c \uae30\uc874 \uc5f0\uad6c\ub294 \uc8fc\ub85c \ub2e8\ubc31\uc9c8 \uc751\uc9d1 \uc790\uccb4\ub97c \uc608\ubc29\ud558\uac70\ub098 \ub2a6\ucd94\ub294 \ubc29\ud5a5\uc5d0 \ucd08\uc810\uc744 \ub9de\ucdb0 \uc654\ub2e4.<\/p>\n<p>\ub2e8\ubc31\uc9c8 \uc751\uc9d1\uc740 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc758 \uacf5\ud1b5 \ubcd1\ud0dc\uc0dd\ub9ac\ub85c \uc778\uc2dd\ub418\uc5b4 \uc654\uc73c\uba70, \uac01 \uc9c8\ud658\ub9c8\ub2e4 \ud575\uc2ec \uc751\uc9d1 \ub2e8\ubc31\uc9c8(\uc608: \ud5cc\ud305\ud2f4, \ubca0\ud0c0\uc544\ubc00\ub85c\uc774\ub4dc, \uc54c\ud30c-\uc2dc\ub274\ud074\ub808\uc778, TDP-43 \ub4f1)\uc774 \ud655\uc778\ub418\uc5b4 \uc654\ub2e4. \uadf8\ub7ec\ub098 &#8216;\ud55c\ubc88 \ub9cc\ub4e4\uc5b4\uc9c4 \uace0\ubd84\uc790 \uc751\uc9d1\uccb4\ub97c \uc5b4\ub5bb\uac8c \ubd84\ud574\ud560 \uac83\uc778\uac00&#8217;\ub294 \uae30\uc220\uc801\u00b7\uc0dd\ubb3c\ud559\uc801 \ud55c\uacc4 \ub54c\ubb38\uc5d0 \ubbf8\ud574\uacb0 \uacfc\uc81c\uc600\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub0b4\ubd80\uc5d0\ub294 \uc2a4\ud2b8\ub808\uc2a4\uc5d0 \ub300\uc751\ud574 \ub2e8\ubc31\uc9c8 \uc5c9\ud0b4\uc744 \ud480\uc5b4\ub0b4\ub294 \ubd84\uc790\ub4e4\uc774 \uc874\uc7ac\ud55c\ub2e4\ub294 \ubcf4\uace0\uac00 \uc788\uc5c8\uc73c\ub098, \uc911\ucd94\uc2e0\uacbd\uacc4 \ubcd1\ub9ac \ud658\uacbd\uc5d0\uc11c\uc758 \uc5ed\ud560\uc740 \uba85\ud655\ud558\uc9c0 \uc54a\uc558\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\ud300\uc740 \uba3c\uc800 \ud5cc\ud305\ud134\ubcd1 \uc138\ud3ec\ubaa8\ub378\uc5d0\uc11c ClpB\uc758 \ubc1c\ud604\ub7c9\uc744 \uc870\uc791\ud574 \uc751\uc9d1\uccb4 \ud615\uc131\uacfc \uc138\ud3ec \uc190\uc0c1 \uc218\uc900\uc744 \ube44\uad50\ud588\ub2e4. ClpB\uac00 \uacb0\ud54d\ub41c \uc0c1\ud0dc\uc5d0\uc11c\ub294 \uc815\uc0c1 \ud5cc\ud305\ud2f4 \ub2e8\ubc31\uc9c8\uc870\ucc28 \uc751\uc9d1\uc774 \ucd09\uc9c4\ub418\uace0 \uc138\ud3ec \uc190\uc0c1\uc774 \uc99d\uac00\ud558\ub294 \uacbd\ud5a5\uc744 \uad00\ucc30\ud588\ub2e4. \ubc18\ub300\ub85c ClpB\ub97c \uacfc\ubc1c\ud604\ud558\uba74 \ub3cc\uc5f0\ubcc0\uc774 \ud5cc\ud305\ud2f4\uc758 \ub3c5\uc131 \uc751\uc9d1\uccb4\uac00 \ud604\uc800\ud788 \uc904\uc5b4\ub4dc\ub294 \uacb0\uacfc\ub97c \uc5bb\uc5c8\ub2e4.<\/p>\n<p>\uc0dd\uc950\ubaa8\ub378\uc5d0\uc11c\ub3c4 \uc720\uc0ac\ud55c \ud6a8\uacfc\uac00 \ud655\uc778\ub418\uc5c8\ub2e4. ClpB \uc218\uc900\uc744 \ub192\uc778 \ub3d9\ubb3c\uc5d0\uc11c\ub294 \ub1cc \uc870\uc9c1 \ub0b4 \uc751\uc9d1\uccb4 \uc591\uc774 \uac10\uc18c\ud588\uace0 \uc2e0\uacbd\uc138\ud3ec \uae30\ub2a5 \uc9c0\ud45c\ub4e4\uc774 \ubd80\ubd84\uc801\uc73c\ub85c \ud68c\ubcf5\ub418\ub294 \uc9d5\ud6c4\uac00 \ub098\ud0c0\ub0ac\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \ubd84\uc790\uc0dd\ubb3c\ud559\uc801\u00b7\ud604\ubbf8\uacbd\uc801 \ubd84\uc11d\uc744 \ud1b5\ud574 \uc751\uc9d1\uccb4\uac00 \ud574\uccb4\ub418\ub294 \uacfc\uc815\uc744 \uc9c1\uc811 \uad00\ucc30\ud588\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uc2e4\ud5d8 \uacb0\uacfc\ub97c \ubc14\ud0d5\uc73c\ub85c ClpB\uc758 \uc791\uc6a9 \uba54\ucee4\ub2c8\uc998\uc744 \uc81c\uc2dc\ud588\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub0b4\ubd80\uc5d0\uc11c ClpB\uac00 \ud45c\uc801 \ub2e8\ubc31\uc9c8\uc744 \uc778\uc2dd\ud574 ATP \uc758\uc874\uc801\uc73c\ub85c \uc751\uc9d1\uccb4\ub97c \ubd84\ud574\ud558\uace0, \uc774 \uacfc\uc815\uc774 \uc138\ud3ec \ub0b4 \ub2e8\ubc31\uc9c8 \ud488\uc9c8\uad00\ub9ac\uc640 \uc2e0\uacbd\uc138\ud3ec \uc0dd\uc874\uc5d0 \uae30\uc5ec\ud55c\ub2e4\uace0 \uc124\uba85\ud55c\ub2e4. \ud574\ub2f9 \uae30\uc804\uc740 \ub17c\ubb38\uc5d0\uc11c \uc0dd\ud654\ud559\uc801\u00b7\uc138\ud3ec \uc0dd\ubb3c\ud559\uc801 \ub370\uc774\ud130\ub85c \ub4b7\ubc1b\uce68\ub418\uc5c8\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uc774\ubc88 \ubc1c\uacac\uc740 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\ud615 \uc9c8\ud658 \uc5f0\uad6c\uc5d0 \uc788\uc5b4 \uc804\ub7b5\uc801 \uc804\ud658\uc810\uc744 \uc81c\uacf5\ud55c\ub2e4. \uc9c0\uae08\uae4c\uc9c0\ub294 &#8216;\uc751\uc9d1\uc744 \ub9c9\ub294 \uac83&#8217;\uc774 \uc8fc\ub41c \uc5f0\uad6c \ubaa9\ud45c\uc600\uc73c\ub098, \uc774\ubbf8 \ud615\uc131\ub41c \uc751\uc9d1\uccb4\ub97c \uc81c\uac70\ud560 \uc218 \uc788\ub2e4\uba74 \uc9c8\ud658\uc758 \uc9c4\ud589\ub41c \ub2e8\uacc4\uc5d0\uc11c\ub3c4 \uae30\ub2a5 \ud68c\ubcf5\uc744 \ub3c4\ubaa8\ud560 \uc218 \uc788\ub2e4. \uc774\ub294 \ud658\uc790 \uce58\ub8cc \ud0c0\uc774\ubc0d\uc758 \ubc94\uc704\ub97c \ub113\ud788\ub294 \uc758\ubbf8\ub97c \uac16\ub294\ub2e4.<\/p>\n<p>\uc784\uc0c1 \uc801\uc6a9\uc744 \uc704\ud574\uc11c\ub294 \ub118\uc5b4\uc57c \ud560 \uacfc\uc81c\uac00 \ub0a8\uc544 \uc788\ub2e4. \uc6b0\uc120 ClpB\ub97c \uc5b4\ub5bb\uac8c \uc548\uc804\ud558\uace0 \uc120\ud0dd\uc801\uc73c\ub85c \ub1cc\uc5d0 \uc804\ub2ec\ud560\uc9c0, \uc7a5\uae30\uc801 \ubc1c\ud604 \uc870\uc808\uc774 \uc2e0\uacbd\uacc4\uc5d0 \ubbf8\uce60 \uc601\ud5a5\uc740 \ubb34\uc5c7\uc778\uc9c0 \ub4f1\uc774 \uac80\uc99d\ub418\uc5b4\uc57c \ud55c\ub2e4. \ub610\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub0b4\ubd80\uc5d0\uc11c\uc758 \uc791\ub3d9 \ud2b9\uc131\uc0c1 \ubd80\uc791\uc6a9 \uac00\ub2a5\uc131\uc744 \uba74\ubc00\ud788 \ud3c9\uac00\ud574\uc57c \ud55c\ub2e4.<\/p>\n<p>\uad6d\ub0b4\uc678 \uc81c\uc57d\u00b7\ubc14\uc774\uc624 \uc0b0\uc5c5\uc5d0\uc11c\ub294 \uc774\ubc88 \uc5f0\uad6c\ub97c \uae30\ubc18\uc73c\ub85c \ub2e8\ubc31\uc9c8 \ubd84\ud574\ub97c \ucd09\uc9c4\ud558\ub294 \uce58\ub8cc\ubc95 \uac1c\ubc1c\uc5d0 \uad00\uc2ec\uc744 \uac00\uc9c8 \uac00\ub2a5\uc131\uc774 \ud06c\ub2e4. \ub2e4\ub9cc \uae30\ucd08\uc5f0\uad6c \ub2e8\uacc4\uc758 \uc131\uacfc\uac00 \uace7\ubc14\ub85c \uc57d\ubb3c\u00b7\uce58\ub8cc\ubc95\uc73c\ub85c \uc804\ud658\ub418\uc9c0\ub294 \uc54a\uc73c\ubbc0\ub85c \uc804\uc784\uc0c1\u00b7\uc784\uc0c1\uc2dc\ud5d8 \uacfc\uc815\uc5d0\uc11c\uc758 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc218\uc801\uc774\ub2e4. \uc131\uacf5 \uc2dc \uc54c\uce20\ud558\uc774\uba38\u00b7\ud30c\ud0a8\uc2a8\u00b7ALS \ub4f1 \ub2e4\ub978 \uc751\uc9d1\uc131 \uc9c8\ud658\uc73c\ub85c\uc758 \ud655\uc7a5\ub3c4 \uae30\ub300\ub41c\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\uc9c8\ud658<\/th>\n<th>\ud575\uc2ec \uc751\uc9d1 \ub2e8\ubc31\uc9c8<\/th>\n<th>\ud604\uc7ac \uce58\ub8cc \ucd08\uc810<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\ud5cc\ud305\ud134\ubcd1<\/td>\n<td>\ub3cc\uc5f0\ubcc0\uc774 \ud5cc\ud305\ud2f4<\/td>\n<td>\uc99d\uc0c1 \uc644\ud654\u00b7\uc751\uc9d1 \uc608\ubc29 \uc5f0\uad6c \uc911\uc2ec<\/td>\n<\/tr>\n<tr>\n<td>\uc54c\uce20\ud558\uc774\uba38\ubcd1<\/td>\n<td>\ubca0\ud0c0\uc544\ubc00\ub85c\uc774\ub4dc\u00b7\ud0c0\uc6b0<\/td>\n<td>\uc751\uc9d1 \uc5b5\uc81c\u00b7\uba74\uc5ed \uce58\ub8cc \uc5f0\uad6c \ud65c\ubc1c<\/td>\n<\/tr>\n<tr>\n<td>\ud30c\ud0a8\uc2a8\ubcd1<\/td>\n<td>\uc54c\ud30c-\uc2dc\ub274\ud074\ub808\uc778<\/td>\n<td>\ub2e8\ubc31\uc9c8 \uc81c\uac70\u00b7\uc2e0\uacbd\ubcf4\ud638 \uc5f0\uad6c \uc9c4\ud589<\/td>\n<\/tr>\n<tr>\n<td>\ub8e8\uac8c\ub9ad\ubcd1(ALS)<\/td>\n<td>TDP-43 \ub4f1<\/td>\n<td>\ubd84\uc790 \ud45c\uc801 \uce58\ub8cc \ubc0f \uc99d\uc0c1 \uad00\ub9ac<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \uc8fc\uc694 \ud1f4\ud589\uc131 \uc2e0\uacbd\uc9c8\ud658\uc5d0\uc11c \uc751\uc9d1 \ub2e8\ubc31\uc9c8\uacfc \uc5f0\uad6c\u00b7\uce58\ub8cc \ucd08\uc810\uc744 \ube44\uad50\ud55c \uac83\uc774\ub2e4. \uae30\uc874 \uc811\uadfc\uc740 \ub300\uccb4\ub85c \uc751\uc9d1 \ud615\uc131\uc744 \uc5b5\uc81c\ud558\uac70\ub098 \uc2e0\uacbd\uc138\ud3ec \uc190\uc0c1\uc744 \ub2a6\ucd94\ub294 \ub370 \uc9d1\uc911\ub418\uc5b4 \uc654\ub2e4. ClpB\ub97c \ud1b5\ud55c &#8216;\uc9c1\uc811 \ubd84\ud574&#8217;\ub294 \uc774\ub7ec\ud55c \uae30\uc874 \uc804\ub7b5\uacfc \ubcf4\uc644\uc801\uc73c\ub85c \uc791\uc6a9\ud560 \uc218 \uc788\ub2e4. \ub2e4\ub9cc \uac01 \uc9c8\ud658\uc758 \ubcd1\ub9ac\uc801 \ud2b9\uc774\uc131 \ub54c\ubb38\uc5d0 \uc801\uc6a9 \uac00\ub2a5\uc131\uc740 \uc9c8\ud658\ubcc4 \ucd94\uac00 \uc5f0\uad6c\ub85c \ud655\uc778\ud574\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uc774\ubc88 \uc131\uacfc\uac00 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\ub97c \ud574\uccb4\ud574 \uc2e0\uacbd \uae30\ub2a5\uc744 \ud68c\ubcf5\ud560 \uc218 \uc788\uc74c\uc744 \uc2e4\ud5d8\uc801\uc73c\ub85c \uc785\uc99d\ud588\ub2e4\ub294 \uc810\uc744 \uac15\uc870\ud588\ub2e4. \uc774\ub294 \uae30\uc874\uc758 \uc608\ubc29 \uc911\uc2ec \uc5f0\uad6c\uc5d0\uc11c \ud55c \ub2e8\uacc4 \ub098\uc544\uac04 \uacb0\uacfc\ub85c \ud3c9\uac00\ub41c\ub2e4.<\/p>\n<blockquote>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ub1cc \uc548\uc5d0 \uc774\ubbf8 \uc313\uc5ec\ubc84\ub9b0 \ub3c5\uc131 \ub2e8\ubc31\uc9c8 \ub369\uc5b4\ub9ac\ub97c \uc9c1\uc811 \ud480\uc5b4\ub0bc \uc218 \uc788\ub294 \uae30\uc804\uc774 \uc2e4\uc81c\ub85c \uc874\uc7ac\ud55c\ub2e4\ub294 \uac83\uc744 \ud655\uc778\ud55c \ub9e4\uc6b0 \uc758\ubbf8 \uc788\ub294 \uacb0\uacfc\uc785\ub2c8\ub2e4.<\/p>\n<p><cite>\uc5c4\uc9c0\uc6d0 \uad50\uc218, DGIST(\uc5f0\uad6c\ucc45\uc784\uc790)<\/cite><\/p><\/blockquote>\n<p>\uc5f0\uad6c\ud300\uc740 \ud5a5\ud6c4 \uc804\ub2ec \ubc29\uc2dd\uacfc \uc548\uc804\uc131 \uac80\uc99d\uc744 \ud3ec\ud568\ud574 \uc784\uc0c1 \uc804 \ub2e8\uacc4 \uc5f0\uad6c\ub97c \ud655\ub300\ud560 \uacc4\ud68d\uc774\ub77c\uace0 \ubc1d\ud614\ub2e4. \ud559\uacc4\uc5d0\uc11c\ub294 \uae30\ucd08\uc801 \uba54\ucee4\ub2c8\uc998 \uaddc\uba85\uc774\uc9c0\ub9cc \uc7a0\uc7ac\ub825\uc774 \ud06c\ub2e4\ub294 \ubc18\uc751\uc774 \ub098\uc624\uace0 \uc788\ub2e4.<\/p>\n<blockquote>\n<p>\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ubc18\uc758 \uc751\uc9d1\uccb4 \ubd84\ud574 \uc811\uadfc\uc740 \uc0c8\ub85c\uc6b4 \uce58\ub8cc \ubaa8\ub2ec\ub9ac\ud2f0\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\uc73c\ub098, \ub1cc \uc804\ub2ec \ubc0f \uc7a5\uae30 \uc548\uc804\uc131 \uac80\uc99d\uc774 \uc6b0\uc120\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n<p><cite>\uad6d\ub0b4 \uc2e0\uacbd\uacfc\ud559 \uc5f0\uad6c\uc790(\uc775\uba85\u00b7\uc804\ubb38\uac00 \uc758\uacac)<\/cite><\/p><\/blockquote>\n<h2>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>ClpB\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0 \uc874\uc7ac\ud558\ub294 \ub2e8\ubc31\uc9c8\ub85c, \uc138\ud3ec \uc2a4\ud2b8\ub808\uc2a4 \uc0c1\ud669\uc5d0\uc11c \ub2e8\ubc31\uc9c8 \uc5c9\ud0b4\uc744 \ud480\uc5b4\ub0b4\ub294 \uc0e4\ud398\ub860\uacc4 \ub2e8\ubc31\uc9c8\uc758 \uc77c\uc885\uc774\ub2e4. \ud5cc\ud305\ud2f4\uc740 CAG \ubc18\ubcf5 \ud655\uc7a5\uc5d0 \uc758\ud574 \ubcc0\ud615\ub418\uba74 \ub3c5\uc131 \uc751\uc9d1\uccb4\ub97c \ud615\uc131\ud574 \uc2e0\uacbd\uc138\ud3ec\ub97c \uc190\uc0c1\uc2dc\ud0a8\ub2e4. \uc138\ud3ec\ubaa8\ub378\uacfc \uc0dd\uc950\ubaa8\ub378\uc740 \uc720\uc804\uc790 \uc870\uc791\uc744 \ud1b5\ud574 \uc9c8\ud658 \ud45c\uc9c0\uc790\ub97c \uc7ac\ud604\ud558\uba70, \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uc758 \uc591\u00b7\uad6c\uc870\u00b7\uc138\ud3ec \uae30\ub2a5 \uc9c0\ud45c\ub97c \ubd84\uc790\u00b7\ud604\ubbf8\uacbd \uae30\ubc95\uc73c\ub85c \ud3c9\uac00\ud55c\ub2e4. \ubcf8 \uc5f0\uad6c\ub294 ClpB \ubc1c\ud604 \uc870\uc808\uacfc \ubd84\uc790\uc801 \uc0c1\ud638\uc791\uc6a9 \ubd84\uc11d\uc744 \ud1b5\ud574 \uc791\ub3d9 \uae30\uc804\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<\/h2>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>ClpB\ub97c \uc778\uccb4 \ub1cc\uc5d0 \uc548\uc804\ud558\uac8c \uc804\ub2ec\ud558\ub294 \uad6c\uccb4\uc801 \ubc29\ubc95\uc740 \uc544\uc9c1 \ud655\ub9bd\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc7a5\uae30\uc801 ClpB \ubc1c\ud604 \uc870\uc808\uc774 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \ubc0f \uc138\ud3ec \ud56d\uc0c1\uc131\uc5d0 \ubbf8\uce60 \uc601\ud5a5\uc740 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4.<\/li>\n<li>\ub3d9\ubb3c\ubaa8\ub378\uc5d0\uc11c \ud655\uc778\ub41c \ud6a8\uacfc\uac00 \uc0ac\ub78c \ud658\uc790\uc5d0\uc11c \ub3d9\uc77c\ud558\uac8c \uc7ac\ud604\ub420\uc9c0\ub294 \uc784\uc0c1\uc2dc\ud5d8\uc744 \ud1b5\ud574 \uc785\uc99d\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>DGIST \uc5f0\uad6c\uc9c4\uc774 \ubc1d\ud78c ClpB\uc758 \uc751\uc9d1\uccb4 \ud574\uccb4 \ub2a5\ub825\uc740 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\ud615 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658 \uc5f0\uad6c\uc5d0 \uc804\ub7b5\uc801 \uc804\ud658\uc744 \uc694\uad6c\ud55c\ub2e4. \ud575\uc2ec\uc740 \uc774\ubbf8 \ud615\uc131\ub41c \ubcd1\uc801 \uc751\uc9d1\uccb4\ub97c \uc81c\uac70\ud574 \uc190\uc0c1\ub41c \uc2e0\uacbd \uae30\ub2a5\uc744 \ud68c\ubcf5\ud560 \uc218 \uc788\ub2e4\ub294 \uc810\uc774\ub2e4. \uadf8\ub7ec\ub098 \uae30\ucd08 \uc5f0\uad6c \uc131\uacfc\uac00 \uc784\uc0c1\uc801 \uce58\ub8cc\uc81c\ub85c \uc774\uc5b4\uc9c0\ub824\uba74 \uc804\ub2ec \uae30\uc220, \uc548\uc804\uc131, \ud6a8\ub2a5\uc758 \ub2e4\ub2e8\uacc4 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p>\ud5a5\ud6c4 \uc5f0\uad6c\ub294 ClpB\ub97c \ud45c\uc801\uc73c\ub85c \ud55c \uc57d\ubb3c \uac1c\ubc1c, \uc720\uc804\uc790 \uc804\ub2ec \ud50c\ub7ab\ud3fc, \uadf8\ub9ac\uace0 \ub2e4\ub978 \uc751\uc9d1\uc131 \uc9c8\ud658\uc73c\ub85c\uc758 \ud655\uc7a5 \uac00\ub2a5\uc131 \ud3c9\uac00\uc5d0 \uc9d1\uc911\ub420 \uac83\uc774\ub2e4. \uc774\ub7ec\ud55c \uacfc\uc815\uc774 \uc131\uacf5\ud558\uba74 \ud658\uc790 \uce58\ub8cc\uc758 \ud68c\ubcf5 \uac00\ub2a5\uc131\uc744 \ud604\uc2e4\ud654\ud558\ub294 \uc911\uc694\ud55c \uc804\ud658\uc810\uc774 \ub420 \uc218 \uc788\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.smnews.co.kr\/default\/index_view_page.php?idx=282289\" target=\"_blank\" rel=\"noopener\">\uc138\uba85\uc77c\ubcf4(\uc5b8\ub860 \ubcf4\ub3c4)<\/a><\/li>\n<li><a href=\"https:\/\/www.dgist.ac.kr\" target=\"_blank\" rel=\"noopener\">DGIST(\uae30\uad00\u00b7\uacf5\uc2dd \ubc1c\ud45c)<\/a><\/li>\n<li><a href=\"https:\/\/www.theranostics.com\" target=\"_blank\" rel=\"noopener\">Theranostics(\ud559\uc220\uc9c0\u00b7\ub17c\ubb38 \uac8c\uc7ac)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d DGIST \ub1cc\uacfc\ud559\uacfc \uc5c4\uc9c0\uc6d0\u00b7\uace0\uc7ac\uc6d0 \uad50\uc218 \uc5f0\uad6c\ud300(\uc81c1\uc800\uc790 \uae40\ud604\ud638 \ubc15\uc0ac\ud6c4\uc5f0\uc218\uc5f0\uad6c\uc6d0)\uc774 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub2e8\ubc31\uc9c8 ClpB\uac00 \ud5cc\ud305\ud134\ubcd1\uc758 \ub3c5\uc131 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\ub97c \uc9c1\uc811 \ud480\uc5b4 \uc81c\uac70\ud558\uace0 \uc190\uc0c1\ub41c \uc2e0\uacbd\uc138\ud3ec \uae30\ub2a5\uc744 \ud68c\ubcf5\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \uc138\ud3ec\u00b7\uc0dd\uc950 \ubaa8\ub378\uc5d0\uc11c \uaddc\uba85\ud588\ub2e4. \uc774 \uc5f0\uad6c\ub294 \uad6d\uc81c \ud559\uc220\uc9c0 Theranostics\uc5d0 \uac8c\uc7ac\ub418\uc5c8\uc73c\uba70 \uacfc\ud559\uae30\uc220\uc815\ubcf4\ud1b5\uc2e0\ubd80\uc640 \ud55c\uad6d\uc5f0\uad6c\uc7ac\ub2e8\uc758 \uc9c0\uc6d0\uc744 \ubc1b\uc558\ub2e4. \uae30\uc874\uc758 &#8216;\uc751\uc9d1 \uc608\ubc29&#8217; \uc804\ub7b5\uc744 \ub118\uc5b4 \uc774\ubbf8 \ud615\uc131\ub41c \uc751\uc9d1\uccb4\ub97c \ubd84\ud574\ud558\ub294 \uce58\ub8cc \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud55c\ub2e4. \ud575\uc2ec \uc0ac\uc2e4 \uc5f0\uad6c\uc9c4: DGIST(\ub300\uad6c\uacbd\ubd81\uacfc\ud559\uae30\uc220\uc6d0) \ub1cc\uacfc\ud559\uacfc &#8230; <a title=\"DGIST \uc5f0\uad6c\ud300, \ud5cc\ud305\ud134\ubcd1 \ub4f1 \ud1f4\ud589\uc131 \ub1cc\uc9c8\ud658 \uce58\ub8cc \uc0c8 \ubc29\ud5a5 \uc81c\uc2dc\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/dgist-clpb-huntington-therapy\/\" aria-label=\"DGIST \uc5f0\uad6c\ud300, \ud5cc\ud305\ud134\ubcd1 \ub4f1 \ud1f4\ud589\uc131 \ub1cc\uc9c8\ud658 \uce58\ub8cc \uc0c8 \ubc29\ud5a5 \uc81c\uc2dc\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":3990,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"DGIST, ClpB\ub85c \ud5cc\ud305\ud134\ubcd1 \uc751\uc9d1\uccb4 \ud574\uccb4 \uaddc\uba85 \u2014 \uc138\uba85\uc77c\ubcf4","rank_math_description":"DGIST \uc5f0\uad6c\uc9c4\uc774 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub2e8\ubc31\uc9c8 ClpB\uac00 \ud5cc\ud305\ud134\ubcd1\uc758 \ub3c5\uc131 \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\ub97c \ubd84\ud574\ud558\uace0 \uc190\uc0c1\ub41c \uc2e0\uacbd \uae30\ub2a5\uc744 \ud68c\ubcf5\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \uc138\ud3ec\u00b7\uc0dd\uc950 \ubaa8\ub378\uc5d0\uc11c \uaddc\uba85\ud574 \uce58\ub8cc \uc804\ub7b5\uc758 \uc804\ud658 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud588\ub2e4.","rank_math_focus_keyword":"DGIST,ClpB,\ud5cc\ud305\ud134\ubcd1,\ub2e8\ubc31\uc9c8\uc751\uc9d1,\ud1f4\ud589\uc131\ub1cc\uc9c8\ud658","footnotes":""},"categories":[2],"tags":[],"class_list":["post-3997","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/3997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=3997"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/3997\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/3990"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=3997"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=3997"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=3997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}