{"id":4573,"date":"2025-12-16T11:07:23","date_gmt":"2025-12-16T02:07:23","guid":{"rendered":"https:\/\/readtrends.com\/ko\/microplastic-rheumatoid-arthritis\/"},"modified":"2025-12-16T11:07:23","modified_gmt":"2025-12-16T02:07:23","slug":"microplastic-rheumatoid-arthritis","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/microplastic-rheumatoid-arthritis\/","title":{"rendered":"\ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc\uc5d0 \uc874\uc7ac\ud574 \uc99d\uc0c1 \uc545\ud654\uc2dc\ucf1c &#8211; \uba54\ub4dc\uc6d4\ub4dc\ub274\uc2a4"},"content":{"rendered":"<article>\n<h2>\ud575\uc2ec \uc694\uc57d<\/h2>\n<p>\uac00\ud1a8\ub9ad\ub300\u00b7\ud3ec\uc2a4\ud14d\u00b7\ub300\uad6c\ub300 \uacf5\ub3d9\uc5f0\uad6c\ud300\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc(RA) \ud658\uc790\uc758 \ud65c\uc561\uc5d0\uc11c \ud3f4\ub9ac\uc2a4\ud2f0\ub80c \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1(PS-MPs)\uc744 \uc138\uacc4 \ucd5c\ucd08\ub85c \uac80\ucd9c\ud588\ub2e4. \uc5f0\uad6c\ub294 Py-GC\/MS\/MS\ub85c PS-MPs\ub97c \uc815\ub7c9\ud654\ud558\uace0, 5\u03bcm \ud06c\uae30\uc758 PS-MPs\uac00 \ud65c\ub9c9\uc12c\uc720\uc544\uc138\ud3ec\uc5d0 \ub0b4\uc7ac\ud654\ub418\uc5b4 NF-\u03baB\u00b7MAPK \uc2e0\ud638\ub97c \ud65c\uc131\ud654\ud568\uc73c\ub85c\uc368 \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778(IL-6, IL-8)\uacfc \uc870\uc9c1\ud30c\uad34 \ud6a8\uc18c(MMP3, MMP9) \ubc1c\ud604\uc744 \ub192\uc5ec \uad00\uc808 \uc190\uc0c1\uc744 \ucd09\uc9c4\ud568\uc744 \uc138\ud3ec \ubc0f \ub3d9\ubb3c\uc2e4\ud5d8\uc73c\ub85c \uc785\uc99d\ud588\ub2e4. \ud574\ub2f9 \uc131\uacfc\ub294 Journal of Hazardous Materials(IF 11.3)\uc5d0 \uac8c\uc7ac\ub418\uc5b4 \uad6d\uc81c \ud559\uacc4\uc758 \uc8fc\ubaa9\uc744 \ubc1b\uc558\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c\uc9c4: \uc720\uc2b9\uc544 \uad50\uc218(\uac00\ud1a8\ub9ad\ub300 \uc758\uc0dd\uba85\uacfc\ud559\uad50\uc2e4, \uacf5\ub3d9 \uad50\uc2e0\uc800\uc790), \uc774\uc218\ud604 \uc5f0\uad6c\uc6d0(\uc81c1\uc800\uc790), \uae40\uc644\uc6b1 \uad50\uc218(\ud3ec\uc2a4\ud14d-\uac00\ud1a8\ub9ad\ub300\uc0dd\uba85\uacf5\ud559\uc5f0\uad6c\uc6d0, \uacf5\ub3d9 \uad50\uc2e0\uc800\uc790), \uae40\uc601\ubbfc \uad50\uc218(\ub300\uad6c\ub300 \ud658\uacbd\uae30\uc220\uacf5\ud559\uacfc) \ub4f1\uc774 \uacf5\ub3d9 \uc218\ud589\ud588\ub2e4.<\/li>\n<li>\ud559\uc220\uac8c\uc7ac: \uc5f0\uad6c \uacb0\uacfc\ub294 Journal of Hazardous Materials(Impact Factor 11.3)\uc5d0 \uc2e4\ub838\ub2e4.<\/li>\n<li>\uac80\ucd9c \ubb3c\uc9c8\uacfc \ud06c\uae30: \ud65c\uc561\uc5d0\uc11c \uac80\ucd9c\ub41c \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc740 \ud3f4\ub9ac\uc2a4\ud2f0\ub80c(PS) \uacc4\uc5f4\ub85c, \uc2e4\ud5d8\uc5d0\ub294 \ub300\ud45c \ud06c\uae30\uc778 5\u03bcm \uc785\uc790\uac00 \uc0ac\uc6a9\ub410\ub2e4(\uba38\ub9ac\uce74\ub77d \uad75\uae30 \uc57d 70\u03bcm \ub300\ube44 \ud6e8\uc52c \uc791\uc740 \ud06c\uae30).<\/li>\n<li>\ubd84\uc11d \uae30\ubc95: \ud658\uc790 \ud65c\uc561\uc758 PS-MPs \uc815\ub7c9\u00b7\ub3d9\uc815\uc5d0\ub294 Py-GC\/MS\/MS(\uc5f4\ubd84\ud574-\uac00\uc2a4\ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\/\uc9c8\ub7c9\ubd84\uc11d)\uac00 \ud65c\uc6a9\ub410\ub2e4.<\/li>\n<li>\uc138\ud3ec \uc2e4\ud5d8: PS-MPs\ub294 \ud658\uc790 \uc720\ub798 \ud65c\ub9c9\uc12c\uc720\uc544\uc138\ud3ec(RA-FLS)\uc5d0 \ub0b4\uc7ac\ud654\ub418\uc5b4 NF-\u03baB\u00b7MAPK \uc2e0\ud638\ub97c \uc720\ub3c4\ud558\uace0, IL-6\u00b7IL-8 \ubc0f MMP3\u00b7MMP9\uc758 \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ucf30\ub2e4.<\/li>\n<li>\ub3d9\ubb3c \uc2e4\ud5d8: \uc7a5\uae30 \ub178\ucd9c\ub41c \uad00\uc808\uc5fc \ubaa8\ub378\uc5d0\uc11c \uad00\uc808 \uc5fc\uc99d\uc774 \uc545\ud654\ub418\uc5c8\uace0, PS-MPs \uc790\uadf9 RA-FLS\ub97c \uc774\uc2dd\ud55c \uc81c\ub178\uadf8\ub798\ud504\ud2b8 \ubaa8\ub378\uc5d0\uc11c\ub294 \uc5f0\uace8 \uce68\uc2dd\uacfc \ub300\uc2dd\uc138\ud3ec \uce68\uc724\uc774 \uc720\uc758\ud558\uac8c \uc99d\uac00\ud588\ub2e4.<\/li>\n<li>\uc758\ubbf8: \uc774\ubc88 \uc5f0\uad6c\ub294 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \ub0b4\ubd80 \uc870\uc9c1\uc5d0 \ucd95\uc801\ub420 \uc218 \uc788\uc73c\uba70 \uc790\uac00\uba74\uc5ed\uc131 \uad00\uc808\uc5fc\uc758 \ubcd1\ud0dc\ub97c \uc2e4\ud5d8\uc801\uc73c\ub85c \uc545\ud654\uc2dc\ud0a8\ub2e4\ub294 \uc9c1\uc811\uc801 \uc99d\uac70\ub97c \uc81c\uc2dc\ud588\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc\uc740 \uba74\uc5ed\uccb4\uacc4\uac00 \uc790\uae30 \uc870\uc9c1\uc744 \uacf5\uaca9\ud574 \ub9cc\uc131 \uc5fc\uc99d\uacfc \uc5f0\uace8\u00b7\uace8 \uc190\uc0c1\uc744 \ucd08\ub798\ud558\ub294 \uc790\uac00\uba74\uc5ed\uc9c8\ud658\uc774\ub2e4. \uae30\uc874 \uc5f0\uad6c\ub294 \uc720\uc804\uc801 \uc694\uc778\uacfc \uba74\uc5ed\ubc18\uc751 \uc911\uc2ec\uc73c\ub85c \uc9c4\ud589\ub3fc \uc654\uc73c\ub098 \ud658\uacbd\uc801 \uc694\uc778\uc774 \uc9c8\ud658 \uacbd\uacfc\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc5d0 \ub300\ud55c \uc2e4\ud5d8\uc801 \uadfc\uac70\ub294 \uc81c\ud55c\uc801\uc774\uc5c8\ub2e4. \ud55c\ud3b8 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc740 \uc0dd\ud65c\u00b7\uc0b0\uc5c5 \uc804\ubc18\uc5d0\uc11c \ube48\ubc88\ud788 \ub178\ucd9c\ub418\uba70, \uccb4\ub0b4 \uc794\ub958\uc640 \uc870\uc9c1 \ucd95\uc801 \uac00\ub2a5\uc131\uc5d0 \ub300\ud55c \uc6b0\ub824\uac00 \ucee4\uc9c0\uace0 \uc788\uc5c8\ub2e4. \uc774\ub7f0 \ubc30\uacbd\uc5d0\uc11c \uc5f0\uad6c\uc9c4\uc740 \ud658\uc790 \ud65c\uc561\uc744 \uc9c1\uc811 \ubd84\uc11d\ud574 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc758 \uc874\uc7ac \uc5ec\ubd80\uc640 \ubcd1\ud0dc\uc0dd\ub9ac\uc801 \uc5ed\ud560\uc744 \uaddc\uba85\ud558\ub294 \ub370 \uc9d1\uc911\ud588\ub2e4.<\/p>\n<p>\ubd84\uc11d \uae30\uc220\uc758 \ubc1c\uc804\ub3c4 \ubcf8 \uc5f0\uad6c\ub97c \uac00\ub2a5\ud558\uac8c \ud588\ub2e4. Py-GC\/MS\/MS\uc640 \uac19\uc740 \uace0\uac10\ub3c4 \uc815\ub7c9\uae30\ubc95\uc740 \ud3f4\ub9ac\uba38 \uc131\ubd84\uc744 \ubd84\ud574\ud574 \uad6c\uc131 \ub2e8\uc704\ubcc4\ub85c \uac80\ucd9c\u00b7\uacc4\ub7c9\ud560 \uc218 \uc788\uc5b4 \uc870\uc9c1 \ub0b4 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc744 \uc815\ud655\ud788 \ub3d9\uc815\ud560 \uc218 \uc788\ub2e4. \ub610\ud55c RA-FLS\ub97c \uc774\uc6a9\ud55c \ud658\uc790 \uc720\ub798 \uc138\ud3ec \ubaa8\ub378\uacfc \uc81c\ub178\uadf8\ub798\ud504\ud2b8\u00b7\uad00\uc808\uc5fc \ub3d9\ubb3c\ubaa8\ub378\uc744 \uc5f0\uacc4\ud574 \uc778\uccb4 \ubcd1\ud0dc\uc640\uc758 \uad00\ub828\uc131\uc744 \uc785\uc99d\ud558\ub294 \ub2e4\uce35\uc801 \uc811\uadfc\uc774 \uc2dc\ub3c4\ub410\ub2e4. \uc774\ub7ec\ud55c \ub2e4\ud559\uc81c\uc801 \ud611\uc5c5\uc740 \ud658\uacbd\uc5ed\ud559\u00b7\uba74\uc5ed\ud559\u00b7\uc0dd\uccb4\ubd84\uc11d \uae30\uc220\uc774 \uacb0\ud569\ud55c \uacb0\uacfc\ubb3c\uc774\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uccab \ub2e8\uacc4\ub85c \uc5f0\uad6c\uc9c4\uc740 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc \ud658\uc790\uc5d0\uc11c \ucc44\ucde8\ud55c \ud65c\uc561\uc744 Py-GC\/MS\/MS\ub85c \ubd84\uc11d\ud574 \ud3f4\ub9ac\uc2a4\ud2f0\ub80c \uacc4\uc5f4\uc758 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc744 \uc815\ub7c9\uc801\uc73c\ub85c \uac80\ucd9c\ud588\ub2e4. \uac80\ucd9c\uc740 \ub2e8\uc21c \uad00\ucc30 \uc218\uc900\uc744 \ub118\uc5b4 \uc131\ubd84\ubcc4 \ub3d9\uc815\uacfc \uc591\uc801 \uce21\uc815\uc744 \ud3ec\ud568\ud574 \uae30\uc874\uc758 \ucd94\uc815 \uac00\uc124\uc744 \uad6c\uccb4\uc801 \ub370\uc774\ud130\ub85c \uc804\ud658\ud588\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774 \uac80\ucd9c \uacb0\uacfc\ub97c \ud1a0\ub300\ub85c \uc138\ud3ec\u00b7\ub3d9\ubb3c\uc2e4\ud5d8 \uc124\uacc4\ub97c \uc9c4\ud589\ud588\ub2e4.<\/p>\n<p>\uc138\ud3ec \uc218\uc900\uc5d0\uc11c\ub294 5\u03bcm \ud06c\uae30\uc758 \ud3f4\ub9ac\uc2a4\ud2f0\ub80c \uc785\uc790\ub97c RA-FLS\uc5d0 \ub178\ucd9c\uc2dc\ud0a8 \uacb0\uacfc \uc785\uc790\uac00 \uc138\ud3ec \ub0b4\ub85c \uc720\uc785\ub418\uc5c8\uace0, \uadf8 \uacb0\uacfc NF-\u03baB\uc640 MAPK \uc2e0\ud638\uc804\ub2ec \uacbd\ub85c\uac00 \ud65c\uc131\ud654\ub418\uc5c8\ub2e4. \uc774\ub85c \uc778\ud574 \uc5fc\uc99d\uc131 \ub9e4\uac1c\ubb3c\uc9c8\uc778 IL-6\u00b7IL-8\uacfc \uc870\uc9c1\ubd84\ud574 \ud6a8\uc18c MMP3\u00b7MMP9\uc758 \ubc1c\ud604\uc774 \uc99d\uac00\ud588\uace0, \uc138\ud3ec\uc758 \uc774\ub3d9\uc131\u00b7\uce68\uc2b5\uc131 \ub610\ud55c \ub192\uc544\uc84c\ub2e4. \uc774\ub7ec\ud55c \ubcc0\ud654\ub294 \uad00\uc808 \uc870\uc9c1\uc758 \uc5fc\uc99d \ubc0f \uad6c\uc870\uc801 \uc190\uc0c1\uc744 \ucd09\uc9c4\ud560 \uc218 \uc788\ub294 \uae30\uc804\uc744 \uc81c\uc2dc\ud55c\ub2e4.<\/p>\n<p>\ub3d9\ubb3c\ubaa8\ub378\uc5d0\uc11c\ub3c4 PS-MPs \uc7a5\uae30\ub178\ucd9c\uc740 \uad00\uc808\uc5fc \uc9c0\ud45c\ub97c \uc545\ud654\uc2dc\ucf30\ub2e4. \ud2b9\ud788 PS-MPs\uc5d0 \uc790\uadf9\ub41c \ud658\uc790 \uc720\ub798 RA-FLS\ub97c \uba74\uc5ed\uacb0\ud54d \ub9c8\uc6b0\uc2a4\uc5d0 \uc774\uc2dd\ud55c \uc81c\ub178\uadf8\ub798\ud504\ud2b8 \ubaa8\ub378\uc5d0\uc11c \uc5f0\uace8 \uce68\uc2dd\uacfc \ub300\uc2dd\uc138\ud3ec\uc758 \uce68\uc724\uc774 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ud558\uac8c \uc99d\uac00\ud588\ub2e4. \uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \uad00\ucc30\ub41c \uc2e0\ud638 \ud65c\uc131\ud654\uac00 \uc870\uc9c1 \uc218\uc900\uc758 \ubcd1\ubcc0 \uc545\ud654\ub85c \uc774\uc5b4\uc9d0\uc744 \ubcf4\uc5ec\uc900\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \ub2e8\uc21c\ud55c \uc624\uc5fc\ubb3c\uc9c8\uc744 \ub118\uc5b4 \uba74\uc5ed \ub9e4\uac1c\uc131 \uc9c8\ud658\uc758 \uc545\ud654 \uc778\uc790\ub85c \uc791\uc6a9\ud560 \uc218 \uc788\uc74c\uc744 \uc2e4\ud5d8\uc801\uc73c\ub85c \uc785\uc99d\ud588\ub2e4. PS-MPs\uc758 \ud06c\uae30(5\u03bcm)\ub294 \uc138\ud3ec \ub0b4 \uc811\uadfc\uc131\uc744 \ub192\uc5ec \ud65c\ub9c9\uc138\ud3ec\uc5d0 \uc9c1\uc811\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\ucce4\uace0, NF-\u03baB\u00b7MAPK \uacbd\ub85c\ub77c\ub294 \ud575\uc2ec \uc5fc\uc99d \uc2e0\ud638\ucd95\uc744 \ud1b5\ud574 \uc0ac\uc774\ud1a0\uce74\uc778 \ubc0f \ub2e8\ubc31\ubd84\ud574 \ud6a8\uc18c\ub97c \uc720\ubc1c\ud588\ub2e4. \uc774\ub7ec\ud55c \ubd84\uc790 \uae30\uc804\uc740 \uad00\uc808 \ub0b4 \uc5fc\uc99d \uc99d\ud3ed\uacfc \uad6c\uc870\uc801 \uc190\uc0c1\uc73c\ub85c \uc5f0\uacb0\ub41c\ub2e4.<\/p>\n<p>\uacf5\uc911\ubcf4\uac74\uc801 \uad00\uc810\uc5d0\uc11c \ubcf4\uba74 \uc0dd\ud65c\ud658\uacbd\uc73c\ub85c\ubd80\ud130\uc758 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1 \ub178\ucd9c\uc774 \ub9cc\uc131 \uc5fc\uc99d\uc9c8\ud658\uc758 \uc911\uc99d\ub3c4\uc5d0 \uae30\uc5ec\ud560 \uac00\ub2a5\uc131\uc740 \uc815\ucc45\uc801\u00b7\uc784\uc0c1\uc801 \ud568\uc758\ub97c \ub9cc\ub4e0\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \ubcd1\uc6d0 \ud658\uacbd \uad00\ub9ac, \uc758\ub8cc\uae30\uae30\u00b7\uc0dd\ud65c\uc6a9\ud488\uc758 \uc18c\uc7ac \uaddc\uc81c, \ud658\uc790 \ub300\uc0c1 \ud658\uacbd \ub178\ucd9c \ucd5c\uc18c\ud654 \uad8c\uace0 \ub4f1\uc774 \ucd94\uac00\ub85c \uac80\ud1a0\ub420 \uc218 \uc788\ub2e4. \ub2e4\ub9cc \uc778\uccb4 \uc5ed\ud559\uc801 \ub178\ucd9c \uc218\uc900\uacfc \uc9c8\ud658 \uc545\ud654\uc758 \uc778\uacfc\uad00\uacc4\ub97c \uc778\uad6c\uc9d1\ub2e8 \uc218\uc900\uc5d0\uc11c \ud655\ub9bd\ud558\ub824\uba74 \ucd94\uac00\uc801\uc778 \uc5ed\ud559 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.<\/p>\n<p>\uad6d\uc81c \ud559\uc220\uc9c0 \ub4f1\uc7ac\ub294 \uc5f0\uad6c\uc758 \ubc29\ubc95\ub860\uc801 \uc5c4\ubc00\uc131\uacfc \uacb0\uacfc\uc758 \uc911\uc694\uc131\uc744 \ub4b7\ubc1b\uce68\ud55c\ub2e4. \uadf8\ub7ec\ub098 \ud55c \uc5f0\uad6c\ub9cc\uc73c\ub85c \ubaa8\ub4e0 \ud658\uacbd \uc694\uc778\uc744 \uc77c\ubc18\ud654\ud560 \uc218\ub294 \uc5c6\uc73c\ubbc0\ub85c \ub2e4\uae30\uad00\u00b7\ub300\uaddc\ubaa8 \ud658\uc790 \ucf54\ud638\ud2b8 \uc5f0\uad6c\uc640 \uc7a5\uae30 \ucd94\uc801\uc774 \ub4a4\ub530\ub77c\uc57c \ud55c\ub2e4. \ub610\ud55c \ub2e4\uc591\ud55c \ud50c\ub77c\uc2a4\ud2f1 \uc720\ud615\uacfc \ud06c\uae30, \ud45c\uba74 \ud2b9\uc131\uc5d0 \ub530\ub978 \uba74\uc5ed\ud559\uc801 \ud6a8\uacfc \ucc28\uc774\ub97c \uaddc\uba85\ud558\ub294 \ud6c4\uc18d \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\ud56d\ubaa9<\/th>\n<th>\uac12\/\uad00\ucc30<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\uac80\ucd9c \ubb3c\uc9c8<\/td>\n<td>\ud3f4\ub9ac\uc2a4\ud2f0\ub80c(PS) \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1<\/td>\n<\/tr>\n<tr>\n<td>\uc8fc\uc694 \ud06c\uae30<\/td>\n<td>5\u03bcm<\/td>\n<\/tr>\n<tr>\n<td>\ubd84\uc11d\ubc95<\/td>\n<td>Py-GC\/MS\/MS<\/td>\n<\/tr>\n<tr>\n<td>\ud65c\uc131\ud654\ub41c \uc2e0\ud638\uacbd\ub85c<\/td>\n<td>NF-\u03baB, MAPK<\/td>\n<\/tr>\n<tr>\n<td>\uc720\ub3c4\ub41c \ubd84\uc790<\/td>\n<td>IL-6, IL-8, MMP3, MMP9<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \ubcf8 \uc5f0\uad6c\uc5d0\uc11c \ud575\uc2ec\uc801\uc73c\ub85c \ud655\uc778\ub41c \ud56d\ubaa9\uc744 \uc694\uc57d\ud55c \uac83\uc774\ub2e4. \ub2e4\ub9cc \ud658\uc790\ubcc4 \uac80\ucd9c\ub7c9 \ubd84\ud3ec, \ub3d9\ubb3c \ubaa8\ub378\uc758 \ub178\ucd9c \ub18d\ub3c4\u00b7\uae30\uac04 \ub4f1 \uc138\ubd80 \uc218\uce58\ub294 \ub17c\ubb38 \ubcf8\ubb38 \ubc0f \ubcf4\uc870\uc790\ub8cc\ub97c \ud655\uc778\ud574\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<blockquote>\n<p>\u201c\uc774\ubc88 \uc5f0\uad6c\ub294 \ud658\uacbd \ub178\ucd9c \ubb3c\uc9c8\uc774 \uba74\uc5ed\uc9c8\ud658\uc758 \ubcd1\ud0dc\uc0dd\ub9ac\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \uc138\ud3ec\uc640 \ub3d9\ubb3c \uc218\uc900\uc5d0\uc11c \uccb4\uacc4\uc801\uc73c\ub85c \uaddc\uba85\ud588\ub2e4.\u201d<\/p>\n<p><cite>\uc720\uc2b9\uc544 \uad50\uc218(\uac00\ud1a8\ub9ad\ub300, \uacf5\ub3d9 \uad50\uc2e0\uc800\uc790)<\/cite><\/p><\/blockquote>\n<p>\uc704 \ubc1c\uc5b8\uc740 \uc5f0\uad6c\uc758 \uc758\uc758\uc640 \ud5a5\ud6c4 \ud658\uacbd\uad00\ub9ac\u00b7\uc9c8\ubcd1 \uc608\ubc29 \uc804\ub7b5\uc5d0 \ub300\ud55c \uae30\ub300\ub97c \uac04\uacb0\ud788 \uc124\uba85\ud55c \uac83\uc774\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uacb0\uacfc\ub97c \uce58\ub8cc \uc9c0\uce68 \ubcc0\uacbd\ubcf4\ub2e4\ub294 \ucd94\uac00 \uc5f0\uad6c\uc640 \uc815\ucc45 \uac80\ud1a0\uc758 \uadfc\uac70\ub85c \uc81c\uc2dc\ud588\ub2e4.<\/p>\n<blockquote>\n<p>\u201c\uc138\ud3ec \uc218\uc900\uc758 \uc2e0\ud638 \ud65c\uc131\ud654\uac00 \uc870\uc9c1 \uc190\uc0c1\uc73c\ub85c \uc774\uc5b4\uc9c4\ub2e4\ub294 \uc2e4\ud5d8\uc801 \uc99d\uac70\ub294 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc758 \uba74\uc5ed\ub3c5\uc131 \uac00\ub2a5\uc131\uc744 \ubd80\uac01\uc2dc\ud0a8\ub2e4.\u201d<\/p>\n<p><cite>\uc5f0\uad6c\ud300 \uacf5\ub3d9\uc131\uba85(\uc5f0\uad6c\uc9c4)<\/cite><\/p><\/blockquote>\n<p>\uacf5\ub3d9\uc131\uba85\uc740 \uc5f0\uad6c \ubc29\ubc95\uc758 \uc5c4\ubc00\uc131\uacfc \ub2e4\uce35\uc801 \uac80\uc99d\uc744 \uac15\uc870\ud558\uba70, \uc778\uacfc\uad00\uacc4 \ud574\uc11d\uc5d0\ub294 \uc2e0\uc911\uc744 \uae30\ud560 \uac83\uc744 \ub367\ubd99\uc600\ub2e4.<\/p>\n<h2>\n<aside>\ubcf4\uc870 \ubaa8\ub4c8<\/aside>\n<\/h2>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>Py-GC\/MS\/MS\ub294 \uc5f4\ubd84\ud574(Pyrolysis)\ub85c \uc2dc\ub8cc\ub97c \ubd84\ud574\ud55c \ub4a4 \uac00\uc2a4\ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c(GC)\uc640 \uc9c8\ub7c9\ubd84\uc11d\uae30(MS)\ub97c \uacb0\ud569\ud574 \uace0\ubd84\uc790 \ubb3c\uc9c8\uc758 \uad6c\uc131 \uc131\ubd84\uc744 \ub3d9\uc815\u00b7\uc815\ub7c9\ud558\ub294 \uae30\ubc95\uc774\ub2e4. \uc774 \ubc29\ubc95\uc740 \uc870\uc9c1\uc774\ub098 \ubcf5\ud569 \ub9e4\ud2b8\ub9ad\uc2a4\uc5d0\uc11c \uc720\ub798\ud55c \ubbf8\ub7c9\uc758 \ud50c\ub77c\uc2a4\ud2f1 \uc131\ubd84\uc744 \uac80\ucd9c\ud558\ub294 \ub370 \uc7a5\uc810\uc774 \uc788\ub2e4. NF-\u03baB\uc640 MAPK\ub294 \uc138\ud3ec \ub0b4\uc5d0\uc11c \uc5fc\uc99d \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc870\uc808\ud558\ub294 \uc8fc\uc694 \uc2e0\ud638\uc804\ub2ec\uacc4\ub85c, \uc774\ub4e4\uc774 \ud65c\uc131\ud654\ub418\uba74 \uc0ac\uc774\ud1a0\uce74\uc778 \ubd84\ube44\uc640 \uc870\uc9c1\ud30c\uad34 \ud6a8\uc18c\uc758 \ud569\uc131\uc774 \uc99d\uac00\ud55c\ub2e4. RA-FLS\ub294 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc \ud658\uc790\uc758 \ud65c\ub9c9\uc5d0\uc11c \uc720\ub798\ud55c \uc12c\uc720\uc544\uc138\ud3ec\ub85c \uad00\uc808 \ub0b4 \uc5fc\uc99d\uacfc \uce68\uc2b5\uc131 \ubcd1\ubcc0 \ud615\uc131\uc5d0 \ud575\uc2ec\uc801 \uc5ed\ud560\uc744 \ud55c\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\ud658\uc790\ubcc4 PS-MPs \ub18d\ub3c4 \ubd84\ud3ec\uc640 \uc784\uc0c1\uc99d\uc0c1 \uc545\ud654\uc758 \uc9c1\uc811\uc801 \uc0c1\uad00\uad00\uacc4\ub294 \ub300\uaddc\ubaa8 \uc5ed\ud559 \uc790\ub8cc\ub85c \ucd94\uac00 \ud655\uc778\uc774 \ud544\uc694\ud558\ub2e4.<\/li>\n<li>\ud3f4\ub9ac\uc2a4\ud2f0\ub80c \uc678 \ub2e4\ub978 \ud50c\ub77c\uc2a4\ud2f1 \uc885\ub958(\uc608: \ud3f4\ub9ac\uc5d0\ud2f8\ub80c, \ud3f4\ub9ac\ud504\ub85c\ud544\ub80c)\uc758 \uad00\uc808 \ub0b4 \uc874\uc7ac \uc5ec\ubd80\uc640 \ubcd1\ud0dc \uc601\ud5a5\uc740 \uc544\uc9c1 \ucda9\ubd84\ud788 \uaddc\uba85\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc2e4\uc81c \uc778\uccb4 \ub178\ucd9c \uacbd\ub85c(\ud761\uc785\u00b7\uc12d\ucde8\u00b7\uc8fc\uc0ac \ub4f1)\ubcc4 \uc870\uc9c1 \ucd95\uc801 \uba54\ucee4\ub2c8\uc998\uacfc \uc7a5\uae30\uc801 \uc601\ud5a5\uc740 \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \uc778\uac04 \ub0b4\ubd80 \uc870\uc9c1\uc5d0 \ucd95\uc801\ub420 \uc218 \uc788\uc73c\uba70, \ud2b9\uc815 \ud06c\uae30\u00b7\uc131\ubd84\uc758 \uc785\uc790\uac00 \uc790\uac00\uba74\uc5ed\uc131 \uad00\uc808\uc5fc\uc758 \ubcd1\ud0dc\ub97c \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \uc2e4\ud5d8\uc801\uc73c\ub85c \uc81c\uc2dc\ud588\ub2e4. \uc5f0\uad6c\ub294 \uac80\ucd9c\u00b7\ubd84\uc790\uae30\uc804\u00b7\ub3d9\ubb3c\ubaa8\ub378\uc744 \uc5f0\uacc4\ud55c \ub2e4\uce35\uc801 \uadfc\uac70\ub97c \uc81c\uacf5\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\uc758\uac00 \ud06c\ub2e4.<\/p>\n<p>\ub2e4\ub9cc \ud55c \uc5f0\uad6c \uacb0\uacfc\ub9cc\uc73c\ub85c \uc77c\ubc18 \uc778\uad6c\uc758 \ub178\ucd9c \uad00\ub9ac \uae30\uc900\uc744 \ubc14\ub85c \ubcc0\uacbd\ud558\uae30\ubcf4\ub2e4\ub294, \ud6c4\uc18d \ub300\uaddc\ubaa8 \uc5ed\ud559\uc5f0\uad6c\uc640 \ub2e4\uc591\ud55c \ubb3c\uc9c8\u00b7\ub178\ucd9c \uc2dc\ub098\ub9ac\uc624\ub97c \ud3ec\uad04\ud558\ub294 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4. \uc784\uc0c1\uacfc \uc815\ucc45 \uce21\uba74\uc5d0\uc11c\ub294 \ud658\uc790 \uad50\uc721\uacfc \ud658\uacbd \ub178\ucd9c \ucd5c\uc18c\ud654 \uc804\ub7b5, \uc758\ub8cc\uae30\uae30\u00b7\uc18c\ube44\uc7ac\uc758 \uc18c\uc7ac \uac80\ud1a0 \ub4f1\uc774 \uc7a5\uae30\uc801\uc73c\ub85c \ub17c\uc758\ub418\uc5b4\uc57c \ud560 \uc0ac\uc548\uc774\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"http:\/\/www.medworld.co.kr\/news\/articleView.html?idxno=254095\" target=\"_blank\" rel=\"noopener\">\uba54\ub4dc\uc6d4\ub4dc\ub274\uc2a4(\uc5b8\ub860)<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/journal\/journal-of-hazardous-materials\" target=\"_blank\" rel=\"noopener\">Journal of Hazardous Materials(\ud559\uc220\uc9c0, \uad6d\uc81c)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \uac00\ud1a8\ub9ad\ub300\u00b7\ud3ec\uc2a4\ud14d\u00b7\ub300\uad6c\ub300 \uacf5\ub3d9\uc5f0\uad6c\ud300\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc(RA) \ud658\uc790\uc758 \ud65c\uc561\uc5d0\uc11c \ud3f4\ub9ac\uc2a4\ud2f0\ub80c \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1(PS-MPs)\uc744 \uc138\uacc4 \ucd5c\ucd08\ub85c \uac80\ucd9c\ud588\ub2e4. \uc5f0\uad6c\ub294 Py-GC\/MS\/MS\ub85c PS-MPs\ub97c \uc815\ub7c9\ud654\ud558\uace0, 5\u03bcm \ud06c\uae30\uc758 PS-MPs\uac00 \ud65c\ub9c9\uc12c\uc720\uc544\uc138\ud3ec\uc5d0 \ub0b4\uc7ac\ud654\ub418\uc5b4 NF-\u03baB\u00b7MAPK \uc2e0\ud638\ub97c \ud65c\uc131\ud654\ud568\uc73c\ub85c\uc368 \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778(IL-6, IL-8)\uacfc \uc870\uc9c1\ud30c\uad34 \ud6a8\uc18c(MMP3, MMP9) \ubc1c\ud604\uc744 \ub192\uc5ec \uad00\uc808 \uc190\uc0c1\uc744 \ucd09\uc9c4\ud568\uc744 \uc138\ud3ec \ubc0f \ub3d9\ubb3c\uc2e4\ud5d8\uc73c\ub85c \uc785\uc99d\ud588\ub2e4. \ud574\ub2f9 \uc131\uacfc\ub294 Journal of Hazardous Materials(IF 11.3)\uc5d0 \uac8c\uc7ac\ub418\uc5b4 \uad6d\uc81c \ud559\uacc4\uc758 \uc8fc\ubaa9\uc744 \ubc1b\uc558\ub2e4. \ud575\uc2ec \uc0ac\uc2e4 \uc5f0\uad6c\uc9c4: \uc720\uc2b9\uc544 &#8230; <a title=\"\ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc\uc5d0 \uc874\uc7ac\ud574 \uc99d\uc0c1 \uc545\ud654\uc2dc\ucf1c &#8211; \uba54\ub4dc\uc6d4\ub4dc\ub274\uc2a4\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/microplastic-rheumatoid-arthritis\/\" aria-label=\"\ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc\uc5d0 \uc874\uc7ac\ud574 \uc99d\uc0c1 \uc545\ud654\uc2dc\ucf1c &#8211; \uba54\ub4dc\uc6d4\ub4dc\ub274\uc2a4\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":4570,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc \uc545\ud654 \uaddc\uba85 - \uba54\ub4dc\uc6d4\ub4dc\ub274\uc2a4","rank_math_description":"\uac00\ud1a8\ub9ad\ub300\u00b7\ud3ec\uc2a4\ud14d\u00b7\ub300\uad6c\ub300 \uacf5\ub3d9\uc5f0\uad6c\ud300\uc774 \ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc \ud658\uc790 \ud65c\uc561\uc5d0\uc11c 5\u03bcm \ud3f4\ub9ac\uc2a4\ud2f0\ub80c \ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1\uc744 Py-GC\/MS\/MS\ub85c \uc138\uacc4 \ucd5c\ucd08 \uac80\ucd9c\ud558\uace0, NF-\u03baB\u00b7MAPK \uacbd\ub85c\ub97c \ud1b5\ud574 \uc5fc\uc99d\uacfc \uc5f0\uace8 \ud30c\uad34\ub97c \ucd09\uc9c4\ud568\uc744 \uc2e4\ud5d8\uc801\uc73c\ub85c \uaddc\uba85\ud588\ub2e4.","rank_math_focus_keyword":"\ubbf8\uc138\ud50c\ub77c\uc2a4\ud2f1,\ub958\ub9c8\ud2f0\uc2a4\uad00\uc808\uc5fc,\ud3f4\ub9ac\uc2a4\ud2f0\ub80c,Py-GC\/MS\/MS,NF-kB,MAPK","footnotes":""},"categories":[2],"tags":[],"class_list":["post-4573","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/4573","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=4573"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/4573\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/4570"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=4573"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=4573"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=4573"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}