{"id":5296,"date":"2025-12-23T18:04:01","date_gmt":"2025-12-23T09:04:01","guid":{"rendered":"https:\/\/readtrends.com\/ko\/fsp1-inhibitor-lung-adenocarcinoma\/"},"modified":"2025-12-23T18:04:01","modified_gmt":"2025-12-23T09:04:01","slug":"fsp1-inhibitor-lung-adenocarcinoma","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/fsp1-inhibitor-lung-adenocarcinoma\/","title":{"rendered":"\ud3d0 \uc120\uc554 \uce58\ub8cc\uc5d0 \ud6a8\uacfc\uc801\uc778 &#8216;FSP1 \uc5b5\uc81c\uc81c&#8217;"},"content":{"rendered":"<article>\n<p><strong>\ud575\uc2ec \uc694\uc57d<\/strong><\/p>\n<p>\ubbf8\uad6d \uc5f0\uad6c\uc9c4\uc774 \ucca0-\uc758\uc874\uc131 \uc138\ud3ec\uc0ac\uba78\uc778 \ud398\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\ub294 \ub2e8\ubc31\uc9c8 FSP1\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \ud3d0\uc120\uc554\uc744 \uce58\ub8cc\ud560 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud588\ub2e4\ub294 \uc5f0\uad6c\uac00 \ubcf4\uace0\ub410\ub2e4. 2025\ub144 12\uc6d4 23\uc77c \ubcf4\ub3c4\uc5d0 \ub530\ub974\uba74, \uc950 \uc2e4\ud5d8\uc5d0\uc11c FSP1 \uc720\uc804\uc790\uac00 \uacb0\ud54d\ub418\uac70\ub098 FSP1 \uc5b5\uc81c\uc81c(icFSP1)\ub97c \ud22c\uc5ec\ud558\uba74 \uc885\uc591 \ud06c\uae30\uac00 \uc904\uc5b4\ub4dc\ub294 \uacb0\uacfc\uac00 \ud655\uc778\ub410\ub2e4. \uc774 \uc5f0\uad6c\ub294 \ud559\uc220\uc9c0 Nature\uc5d0 \ubc1c\ud45c\ub41c \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc14\ud0d5\uc73c\ub85c \ud558\uba70, \uc5f0\uad6c\uc9c4 \uc18c\uc18d\uc740 NYU Langone Health\/NYU Grossman School of Medicine\uc774\ub2e4. \ube44\ud761\uc5f0\uc790 \ud3d0\uc554 \ud658\uc790 \uac00\uc6b4\ub370 \uc57d 40%\uac00 \ud3d0\uc120\uc554\uc774\ub77c\ub294 \uc810\uc5d0\uc11c \uc784\uc0c1\uc801 \ud30c\uae09\ub825\uc774 \uc8fc\ubaa9\ub41c\ub2e4.<\/p>\n<p><strong>\ud575\uc2ec \uc0ac\uc2e4<\/strong><\/p>\n<ul>\n<li>\uc5b8\ub860 \ubcf4\ub3c4\uc77c: 2025\ub144 12\uc6d4 23\uc77c, \uad00\ub828 \ubcf4\ub3c4\ub294 \ud6c4\uc0dd\uc2e0\ubcf4\uc5d0 \uac8c\uc7ac\ub418\uc5c8\ub2e4.<\/li>\n<li>\uc5f0\uad6c \uac8c\uc7ac\uc9c0: \uc5f0\uad6c \uacb0\uacfc\ub294 Nature \uad00\ub828 \ubcf4\uace0\ub85c \uc18c\uac1c\ub418\uc5c8\ub2e4(\uc5b8\ub860 \ubcf4\ub3c4 \uae30\uc900).<\/li>\n<li>\ud45c\uc801 \ub2e8\ubc31\uc9c8: FSP1(ferroptosis suppressor protein 1)\uc740 \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uc800\ud574 \uc5ed\ud560\uc744 \ud558\ub294 \ub2e8\ubc31\uc9c8\ub85c \uc9c0\ubaa9\ub418\uc5c8\ub2e4.<\/li>\n<li>\uc2e4\ud5d8 \uacb0\uacfc: FSP1 \uc720\uc804\uc790\uac00 \uacb0\uc190\ub41c \uc950\uc758 \uc554\uc138\ud3ec\uc5d0\uc11c\ub294 \uc138\ud3ec\uc0ac\uba78\uc774 \uc99d\uac00\ud558\uace0 \uc885\uc591 \ud06c\uae30\uac00 \uac10\uc18c\ud588\ub2e4\ub294 \ubcf4\uace0\uac00 \uc788\ub2e4.<\/li>\n<li>\uc57d\ubb3c \ud6c4\ubcf4: icFSP1\uc774\ub77c\ub294 FSP1 \uc5b5\uc81c\uc81c\ub97c \uc950\uc5d0 \ud22c\uc5ec\ud588\uc744 \ub54c \uc720\uc0ac\ud55c \ud56d\uc885\uc591 \ud6a8\uacfc\uac00 \uad00\ucc30\ub418\uc5c8\ub2e4.<\/li>\n<li>\ube44\uad50 \ud45c\uc801: GPX4(glutathione peroxidase 4)\ub294 \uae30\uc874\uc5d0 \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uad00\ub828 \ud56d\uc554 \ud45c\uc801\uc73c\ub85c \uad00\uc2ec\uc744 \ubc1b\uc544\uc654\uc73c\uba70, \uc5f0\uad6c\uc9c4\uc740 FSP1 \uc5b5\uc81c\uac00 \uc815\uc0c1\uc138\ud3ec \uc601\ud5a5\uc740 \uc801\uace0 \uc554\uc138\ud3ec\uc5d0 \ub354 \ucde8\uc57d\ud558\ub2e4\uace0 \ud3c9\uac00\ud588\ub2e4.<\/li>\n<li>\uc784\uc0c1\uc801 \ub9e5\ub77d: \ube44\ud761\uc5f0\uc790 \ud3d0\uc554 \ud658\uc790 \uc911 \uc57d 40%\uac00 \ud3d0\uc120\uc554\uc73c\ub85c \ubd84\ub958\ub418\uc5b4 \uc0c8\ub85c\uc6b4 \ud45c\uc801 \uce58\ub8cc\uc758 \ud544\uc694\uc131\uc774 \ud06c\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\ud398\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc138\ud3ec \ub0b4 \ucca0\uacfc \uc9c0\uc9c8 \uc0b0\ud654\uc5d0 \uc758\ud574 \ucd09\ubc1c\ub418\ub294 \ube44\uc804\ud615\uc801 \uc138\ud3ec\uc0ac\uba78 \uacbd\ub85c\ub85c, \ucd5c\uadfc \uc218\ub144\uac04 \uc554 \uce58\ub8cc\uc758 \uc0c8\ub85c\uc6b4 \uc811\uadfc\ubc95\uc73c\ub85c \ub5a0\uc62c\ub790\ub2e4. \uc804\ud1b5\uc801 \ud56d\uc554\uc81c\ub294 DNA \ud569\uc131 \uc5b5\uc81c\ub098 \uc138\ud3ec\ubd84\uc5f4 \ucc28\ub2e8\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd94\uc9c0\ub9cc, \ud398\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud558\uba74 \uae30\uc874 \uce58\ub8cc\uc5d0 \ub0b4\uc131\uc744 \ubcf4\uc774\ub294 \uc554\uc138\ud3ec\ub97c \ucd94\uac00\ub85c \uc81c\uac70\ud560 \uc218 \uc788\ub2e4\ub294 \uae30\ub300\uac00 \uc788\ub2e4. \ud2b9\ud788 GPX4\uac00 \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c \uae30\uc804\uc758 \uc8fc\uc694 \uc778\uc790\ub85c \uc54c\ub824\uc9c0\uba74\uc11c GPX4 \uc5b5\uc81c\ub97c \ud1b5\ud55c \ud56d\uc554 \uc804\ub7b5\uc774 \uc5f0\uad6c\ub418\uc5b4 \uc654\ub2e4. \uadf8\ub7ec\ub098 GPX4 \uc5b5\uc81c\ub294 \uc815\uc0c1\uc138\ud3ec \ub3c5\uc131 \uc704\ud5d8\uc774 \uc788\uace0, \uc120\ud0dd\uc801 \ud45c\uc801\ud654\uac00 \uacfc\uc81c\ub85c \uc9c0\uc801\ub418\uc5b4 \uc654\ub2e4.<\/p>\n<p>\uc774\ub7ec\ud55c \ub9e5\ub77d\uc5d0\uc11c FSP1\uc740 \ud398\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\ub294 \ub610 \ub2e4\ub978 \ubd84\uc790 \uacbd\ub85c\ub85c \uc8fc\ubaa9\ubc1b\uae30 \uc2dc\uc791\ud588\ub2e4. FSP1\uc758 \uc5b5\uc81c\uac00 \uc554\uc138\ud3ec\uc5d0\uc11c \uc120\ud0dd\uc801\uc73c\ub85c \ud398\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ucd09\ubc1c\ud560 \uc218 \uc788\ub2e4\uba74, \uce58\ub8cc \ud6a8\uacfc\ub294 \uc720\uc9c0\ud558\uba74\uc11c \uc815\uc0c1\uc870\uc9c1 \ud53c\ud574\ub294 \uc904\uc774\ub294 \uac00\ub2a5\uc131\uc774 \uc788\ub2e4. \ud3d0\uc120\uc554\uc740 \ube44\ud761\uc5f0\uc790\uc5d0\uc11c\ub3c4 \ube48\ub3c4\uac00 \ub192\uace0 \ud45c\uc801 \uce58\ub8cc\uac00 \ud56d\uc0c1 \uc801\uc6a9 \uac00\ub2a5\ud55c \uac83\uc740 \uc544\ub2c8\uc5b4\uc11c \uc0c8\ub85c\uc6b4 \ubd84\uc790\ud45c\uc801\uc758 \ud544\uc694\uc131\uc774 \uc9c0\uc18d\ub418\uc5b4 \uc654\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774\ub7ec\ud55c \uc784\uc0c1\uc801 \ud544\uc694\uc131 \uc704\uc5d0\uc11c FSP1\uc744 \ud3c9\uac00\ud588\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\ud300\uc740 \uc720\uc804\uc790 \uc870\uc791 \uc950 \ubaa8\ub378\uc5d0\uc11c FSP1 \uacb0\uc190 \uc0c1\ud0dc\ub97c \ub9cc\ub4e0 \ub4a4 \uc554\uc138\ud3ec\uc758 \uc0dd\uc874\ub960\uacfc \uc885\uc591 \uc131\uc7a5 \ubcc0\ud654\ub97c \uad00\ucc30\ud588\ub2e4. \uadf8 \uacb0\uacfc FSP1\uc774 \uacb0\ud54d\ub41c \uc885\uc591\uc5d0\uc11c\ub294 \uc9c0\uc9c8 \uacfc\uc0b0\ud654\uc640 \ud65c\uc131\uc0b0\uc18c \uc99d\uac00\ub85c \uc778\ud55c \uc138\ud3ec\uc0ac\uba78\uc774 \uc99d\uac00\ud588\uace0, \uc804\uccb4\uc801\uc778 \uc885\uc591 \ubd80\ud53c\uac00 \uc720\uc758\ud558\uac8c \uac10\uc18c\ud588\ub2e4. \ub3d9\uc77c\ud55c \uc2e4\ud5d8 \uc870\uac74\uc5d0\uc11c icFSP1\uc774\ub77c\ub294 \uc18c\ubd84\uc790 \uc5b5\uc81c\uc81c\ub97c \ud22c\uc5ec\ud55c \uc950\uc5d0\uc11c\ub3c4 \uc885\uc591 \ucd95\uc18c \ud6a8\uacfc\uac00 \uc7ac\ud604\ub418\uc5c8\ub2e4\ub294 \uc810\uc774 \ubcf4\uace0\ub418\uc5c8\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 FSP1 \uc5b5\uc81c\uac00 GPX4 \ud45c\uc801\ud654\uc640\ub294 \ub2e4\ub978 \uae30\uc804\uc801 \ud2b9\uc131\uc744 \ubcf4\uc778\ub2e4\uace0 \uc124\uba85\ud588\ub2e4. \ubcf4\ub3c4\uc5d0 \ub530\ub974\uba74 FSP1 \uc5b5\uc81c\ub294 \uc554\uc138\ud3ec\uc758 \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uc720\ub3c4\uc5d0 \ub354 \ubbfc\uac10\ud558\uba74\uc11c\ub3c4 \uc815\uc0c1\uc138\ud3ec\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc740 \uc0c1\ub300\uc801\uc73c\ub85c \uc801\uc5c8\ub2e4\uace0 \ud55c\ub2e4. \ub2e4\ub9cc, \ub3d9\ubb3c \uc2e4\ud5d8 \uc218\uc900\uc758 \uacb0\uacfc\ub85c \uc784\uc0c1 \uc801\uc6a9 \uc804 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4\ub294 \uc810\ub3c4 \ud568\uaed8 \uc81c\uc2dc\ub418\uc5c8\ub2e4.<\/p>\n<p>\uc5f0\uad6c \ub0b4\uc5ed\uc5d0\ub294 \uc57d\ubb3c \uc804\ub2ec \ubc29\ubc95, \ud22c\uc5ec \uc6a9\ub7c9 \ubc0f \uce58\ub8cc \uc9c0\uc18d\uc131 \ub4f1 \uc804\uc784\uc0c1 \ub2e8\uacc4\uc5d0\uc11c \ud3c9\uac00\ud574\uc57c \ud560 \uc694\uc18c\ub4e4\uc774 \ud3ec\ud568\ub418\uc5b4 \uc788\ub2e4. \uc5f0\uad6c\ub294 \uae30\ubcf8\uc801\uc73c\ub85c \uae30\ucd08\u00b7\uc804\uc784\uc0c1 \uc131\uaca9\uc744 \ub760\uba70, \uc778\uac04 \ub300\uc0c1 \uc784\uc0c1\uc2dc\ud5d8\uc73c\ub85c \uc774\uc5b4\uc9c0\uae30\uae4c\uc9c0 \ucd94\uac00 \uc790\ub8cc\uc640 \uc548\uc804\uc131 \uac80\uc99d\uc774 \uc694\uad6c\ub41c\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uacfc\ud559\uc801\uc73c\ub85c \uc774\ubc88 \uacb0\uacfc\ub294 \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \ub2e4\ubcc0\ud654 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc900\ub2e4. GPX4 \uc911\uc2ec\uc758 \uc811\uadfc\uc5d0 \ub354\ud574 FSP1\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc804\ub7b5\uc740 \uce58\ub8cc \uc120\ud0dd\uc9c0\ub97c \ub113\ud790 \ubfd0 \uc544\ub2c8\ub77c, \uc11c\ub85c \ub2e4\ub978 \uae30\uc804\uc744 \ubcd1\uc6a9\ud588\uc744 \ub54c \uc0c1\uc2b9\ud6a8\uacfc\ub97c \ub0bc \uc7a0\uc7ac\ub825\uc774 \uc788\ub2e4. \ud2b9\ud788 \uc57d\ubb3c \ubbfc\uac10\ub3c4\uac00 \uc11c\ub85c \ub2e4\ub978 \ud658\uc790\uad70\uc744 \uc2dd\ubcc4\ud574 \ub9de\ucda4\ud615 \uce58\ub8cc\ub85c \ud655\uc7a5\ud560 \uc218 \uc788\ub294 \uc5ec\uc9c0\uac00 \uc788\ub2e4.<\/p>\n<p>\uc784\uc0c1\uc801 \uad00\uc810\uc5d0\uc11c\ub294 \ube44\ud761\uc5f0\uc790 \uc911\uc2ec\uc758 \ud3d0\uc120\uc554 \uce58\ub8cc\uc5d0\uc11c \uc911\uc694\ud55c \uc9c4\uc804\uc774 \ub420 \uc218 \uc788\ub2e4. \ud604\uc7ac \ud45c\uc801\uce58\ub8cc\uac00 \uac00\ub2a5\ud55c \uc720\uc804\uc790 \ubcc0\uc774\ub97c \uac16\uc9c0 \uc54a\uc740 \ud658\uc790\uad70\uc774\ub098 \uae30\uc874 \ud45c\uc900\uc694\ubc95\uc5d0 \ubc18\uc751\ud558\uc9c0 \uc54a\ub294 \ud658\uc790\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \uc635\uc158\uc744 \uc81c\uc2dc\ud560 \uc218 \uc788\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ubbf8\uac00 \ud06c\ub2e4. \ub2e4\ub9cc \ub3d9\ubb3c \uc2e4\ud5d8 \uacb0\uacfc\ub294 \uc778\uac04\uc5d0\uc11c \uadf8\ub300\ub85c \uc7ac\ud604\ub418\uc9c0 \uc54a\uc744 \uc218 \uc788\uc5b4, \ub3c5\uc131 \ud3c9\uac00\uc640 \uc6a9\ub7c9 \uc124\uc815\uc774 \ud575\uc2ec \ubcc0\uc218\uac00 \ub420 \uac83\uc774\ub2e4.<\/p>\n<p>\uc57d\ubb3c \uac1c\ubc1c \uce21\uba74\uc5d0\uc11c\ub294 icFSP1\uacfc \uac19\uc740 FSP1 \uc5b5\uc81c\uc81c\uc758 \uc57d\ub3d9\ud559, \uc57d\ub825\ud559, \uc7a5\uae30 \ub3c5\uc131 \uc5ec\ubd80\ub97c \uccb4\uacc4\uc801\uc73c\ub85c \uac80\uc99d\ud574\uc57c \ud55c\ub2e4. \ub610\ud55c \ub0b4\uc131 \ubc1c\uc0dd \uac00\ub2a5\uc131\uacfc \ubcd1\uc6a9\uc694\ubc95(\uc608: \uba74\uc5ed\ud56d\uc554\uc81c, \ud45c\uc801\uce58\ub8cc\uc81c)\uacfc\uc758 \uc0c1\ud638\uc791\uc6a9\uc5d0 \ub300\ud55c \uc804\uc784\uc0c1 \uc5f0\uad6c\uac00 \ub530\ub77c\uc57c \ud55c\ub2e4. \uaddc\uc81c \uc2b9\uc778 \ubc0f \uc784\uc0c1\uc2dc\ud5d8 \ub2e8\uacc4\ub85c\uc758 \uc774\ud589\uc5d0\ub294 \uc218\ub144\uc758 \uc2dc\uac04\uc774 \uc18c\uc694\ub420 \uac83\uc73c\ub85c \uc608\uc0c1\ub41c\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\ud56d\ubaa9<\/th>\n<th>GPX4 \ud45c\uc801\ud654<\/th>\n<th>FSP1 \ud45c\uc801\ud654<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\uc8fc\uc694 \uae30\ub2a5<\/td>\n<td>\uae00\ub8e8\ud0c0\uce58\uc628 \uc758\uc874\uc801 \uc9c0\uc9c8\uacfc\uc0b0\ud654 \uc5b5\uc81c<\/td>\n<td>\ud398\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\uc758 \ub300\uccb4 \uacbd\ub85c<\/td>\n<\/tr>\n<tr>\n<td>\ub3d9\ubb3c\uc2e4\ud5d8 \uacb0\uacfc<\/td>\n<td>\ud56d\uc554 \ud6a8\uacfc \ubcf4\uace0 \ub2e4\uc218<\/td>\n<td>FSP1 \uacb0\ud54d\/\uc5b5\uc81c\ub85c \uc885\uc591 \ucd95\uc18c \uad00\ucc30<\/td>\n<\/tr>\n<tr>\n<td>\uc815\uc0c1\uc138\ud3ec \uc601\ud5a5<\/td>\n<td>\ub3c5\uc131 \uc6b0\ub824<\/td>\n<td>\uc5f0\uad6c\uc9c4\uc740 \uc601\ud5a5\uc774 \uc801\ub2e4\uace0 \uc81c\uc2dc<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ube44\uad50\ud45c\ub294 \uc5b8\ub860 \ubcf4\ub3c4\uc640 \uc5f0\uad6c\uc9c4 \uc124\uba85\uc744 \ubc14\ud0d5\uc73c\ub85c \uc694\uc57d\ud55c \uac83\uc73c\ub85c, \uac01 \ud45c\uc801\uc758 \uc804\uc784\uc0c1\u00b7\uc784\uc0c1 \ub370\uc774\ud130\uc758 \ubc94\uc704\uc640 \uc131\uaca9\uc740 \uc0c1\uc774\ud558\ub2e4. \ud2b9\ud788 FSP1 \uad00\ub828 \ub370\uc774\ud130\ub294 \ud604\uc7ac \uc804\uc784\uc0c1 \uc218\uc900\uc774 \ub300\ubd80\ubd84\uc774\uba70, \uc784\uc0c1\uc801 \uc548\uc804\uc131\uacfc \ud6a8\uc6a9\uc131\uc740 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c\uc9c4\uc758 \uc124\uba85\uacfc \uc678\ubd80 \uc804\ubb38\uac00\uc758 \ud3c9\uac00\ub294 \uc2e0\uc911\ud558\uc9c0\ub9cc \uae30\ub300\uac10\uc744 \ub3d9\uc2dc\uc5d0 \ubcf4\uc5ec\uc900\ub2e4.<\/p>\n<blockquote>\n<p>\uc950 \ubaa8\ub378\uc5d0\uc11c FSP1 \uc5b5\uc81c\uac00 \uc885\uc591 \uac10\uc18c\ub97c \uc77c\uad00\ub418\uac8c \uc720\ub3c4\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc784\uc0c1 \uc804\uac1c \uac00\ub2a5\uc131\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n<p><cite>NYU Langone \uc5f0\uad6c\ud300(\ud559\uacc4\u00b7\uc5f0\uad6c\uc9c4)<\/cite><\/p><\/blockquote>\n<p>\uc774 \ubc1c\uc5b8\uc740 \uc5f0\uad6c \uacb0\uacfc\uc758 \ud575\uc2ec \uc131\uacfc\ub97c \uc694\uc57d\ud55c \uac83\uc73c\ub85c, \uc5f0\uad6c\uc9c4\uc740 \uc778\uac04 \ub300\uc0c1 \uc801\uc6a9 \uc804 \ucd94\uac00 \uc548\uc804\uc131 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n<blockquote>\n<p>\ub3d9\ubb3c \uc2e4\ud5d8\uc740 \uc720\ub9dd\ud558\uc9c0\ub9cc, \uc778\uac04\uc5d0\uc11c\uc758 \uc57d\ub3d9\ud559\uacfc \ub3c5\uc131 \ud504\ub85c\ud544\uc740 \ubcc4\ub3c4\uc758 \uac80\uc99d\uc744 \uc694\ud55c\ub2e4. \uc784\uc0c1\uc801 \uae30\ub300\ub97c \ud604\uc2e4\ud654\ud558\ub824\uba74 \ub2e4\ub2e8\uacc4 \uc2dc\ud5d8\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p><cite>\uc784\uc0c1\uc885\uc591\ud559 \uc804\ubb38\uac00(\ud559\uacc4)<\/cite><\/p><\/blockquote>\n<p>\ud574\uc678\u00b7\uad6d\ub0b4 \ud658\uc790\ub2e8\uccb4 \ubc0f \uc784\uc0c1\uc758\ub4e4\uc740 \uc0c8 \ud45c\uc801\uc758 \ub4f1\uc7a5\uc744 \ud658\uc601\ud558\uba74\uc11c\ub3c4 \uc784\uc0c1\uc2dc\ud5d8\uc774 \ud22c\uba85\ud558\uac8c \uc9c4\ud589\ub420 \uac83\uc744 \uc694\uad6c\ud558\ub294 \ubaa9\uc18c\ub9ac\ub97c \ub0c8\ub2e4.<\/p>\n<h2>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>\ud398\ub86d\ud1a0\uc2dc\uc2a4(ferroptosis)\ub294 \ucca0 \uc758\uc874\uc801 \uc9c0\uc9c8 \uacfc\uc0b0\ud654\uc5d0 \uc758\ud574 \ucd09\ubc1c\ub418\ub294 \uc138\ud3ec\uc0ac\uba78 \ud615\ud0dc\ub85c, \uae30\uc874\uc758 \uc544\ud3fd\ud1a0\uc2dc\uc2a4\ub098 \uad34\uc0ac\uc640 \uad6c\ubcc4\ub41c\ub2e4. GPX4\ub294 \uae00\ub8e8\ud0c0\uce58\uc628 \uc758\uc874\uc801 \ud6a8\uc18c\ub85c \uc9c0\uc9c8 \uacfc\uc0b0\ud654\ub97c \uc5b5\uc81c\ud574 \ud398\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ub9c9\uc544\uc654\ub2e4. FSP1\uc740 GPX4\uc640\ub294 \ub2e4\ub978 \uacbd\ub85c\ub85c \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\uc5d0 \uad00\uc5ec\ud558\uba70, \uc774 \uc5b5\uc81c\ub97c \ud574\uc81c\ud558\uba74 \uc9c0\uc9c8 \uacfc\uc0b0\ud654\uac00 \uc99d\uac00\ud574 \uc138\ud3ec\uc0ac\uba78\uc774 \ucd09\uc9c4\ub420 \uc218 \uc788\ub2e4. icFSP1\uc740 \uc5f0\uad6c\uc5d0\uc11c \uc0ac\uc6a9\ub41c FSP1 \uc5b5\uc81c\uc81c \ud6c4\ubcf4\ubb3c\uc9c8\uc758 \uc774\ub984\uc774\ub2e4. \uc804\uc784\uc0c1 \uc5f0\uad6c\ub294 \ubcf4\ud1b5 \uc138\ud3ec\uc8fc \uc2e4\ud5d8, \ub3d9\ubb3c\ubaa8\ub378, \uc57d\ub9ac\u00b7\ub3c5\uc131 \ud3c9\uac00\uc758 \uc21c\uc11c\ub85c \uc9c4\ud589\ub41c\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<\/h2>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\uc5f0\uad6c\uac00 \ub3d9\ubb3c\uc2e4\ud5d8 \uc911\uc2ec\uc774\ubbc0\ub85c \uc778\uac04\uc5d0\uc11c \ub3d9\uc77c\ud55c \ud6a8\ub2a5\uacfc \uc548\uc804\uc131\uc774 \ud655\ubcf4\ub420\uc9c0\ub294 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>icFSP1\uc758 \uc7a5\uae30 \ub3c5\uc131, \uc57d\ubb3c\uc0c1\ud638\uc791\uc6a9, \uc801\uc815 \uc6a9\ub7c9 \ub4f1\uc740 \uc544\uc9c1 \ubcf4\uace0\uc11c \ub610\ub294 \ubcf4\ub3c4\uc5d0\uc11c \ucda9\ubd84\ud788 \uc81c\uc2dc\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc5f0\uad6c\uc5d0\uc11c \uad00\ucc30\ub41c \uc815\uc0c1\uc138\ud3ec\uc5d0 \ub300\ud55c \ub0ae\uc740 \uc601\ud5a5\uc774\ub77c\ub294 \uc8fc\uc7a5\uc740 \ub354 \ub9ce\uc740 \ub3c5\uc131 \ub370\uc774\ud130\ub85c \uac80\uc99d\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \ubcf4\ub3c4\ub294 \ud398\ub86d\ud1a0\uc2dc\uc2a4 \uc870\uc808 \uc778\uc790\uc778 FSP1\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\ub294 \uc804\ub7b5\uc774 \ud3d0\uc120\uc554 \uce58\ub8cc\uc758 \uc0c8\ub85c\uc6b4 \uac00\ub2a5\uc131\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4. \uc804\uc784\uc0c1 \uc218\uc900\uc5d0\uc11c\uc758 \uc885\uc591 \ucd95\uc18c \uacb0\uacfc\ub294 \uace0\ubb34\uc801\uc774\uc9c0\ub9cc, \uc774\ub97c \uc784\uc0c1\uc801 \uc131\uacf5\uc73c\ub85c \uc5f0\uacb0\ud558\ub824\uba74 \uc548\uc804\uc131\u00b7\uc57d\ub3d9\ud559\u00b7\ub0b4\uc131 \ubb38\uc81c\ub97c \ud574\uacb0\ud574\uc57c \ud55c\ub2e4. \ud2b9\ud788 \ud658\uc790\uad70 \uc120\ubcc4, \ubcd1\uc6a9\uc694\ubc95 \uc124\uacc4, \uc7a5\uae30 \uc548\uc804\uc131 \ubaa8\ub2c8\ud130\ub9c1\uc774 \ud5a5\ud6c4 \uc5f0\uad6c\uc758 \ud575\uc2ec \uacfc\uc81c\uac00 \ub420 \uac83\uc774\ub2e4.<\/p>\n<p>\ub3c5\uc790\ub294 \uc774\ubc88 \uc5f0\uad6c\ub97c \u2018\uc720\ub9dd\ud55c \uc804\uc784\uc0c1 \uc131\uacfc\u2019\ub85c \uc774\ud574\ud558\ub418, \uc784\uc0c1 \uc801\uc6a9\uae4c\uc9c0\ub294 \uc218\ub144\uc758 \uac80\uc99d\uacfc \uaddc\uc81c \uc808\ucc28\uac00 \ud544\uc694\ud558\ub2e4\ub294 \uc810\uc744 \uae30\uc5b5\ud574\uc57c \ud55c\ub2e4. \ud5a5\ud6c4 \uc784\uc0c1\uc2dc\ud5d8 \uc9c4\ud589 \uc0c1\ud669\uacfc \ub3c5\ub9bd\uc801 \ub370\uc774\ud130 \uacf5\uac1c\ub97c \ud1b5\ud574 \uc2e4\ud6a8\uc131\uc774 \ud655\uc778\ub418\ub294\uc9c0 \uc9c0\uc18d\uc801\uc73c\ub85c \uc810\uac80\ud560 \ud544\uc694\uac00 \uc788\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"http:\/\/www.whosaeng.com\/166818\" target=\"_blank\" rel=\"noopener\">\ud6c4\uc0dd\uc2e0\ubcf4 \ubcf4\ub3c4(\uc5b8\ub860 \ubcf4\ub3c4, 2025-12-23)<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\" target=\"_blank\" rel=\"noopener\">Nature(\ud559\uc220\uc9c0, \uad00\ub828 \uc5f0\uad6c \uac8c\uc7ac\uc9c0)<\/a><\/li>\n<li><a href=\"https:\/\/nyulangone.org\" target=\"_blank\" rel=\"noopener\">NYU Langone Health\/NYU Grossman School of Medicine(\ud559\uacc4\u00b7\uc5f0\uad6c\uae30\uad00)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \ubbf8\uad6d \uc5f0\uad6c\uc9c4\uc774 \ucca0-\uc758\uc874\uc131 \uc138\ud3ec\uc0ac\uba78\uc778 \ud398\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\ub294 \ub2e8\ubc31\uc9c8 FSP1\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \ud3d0\uc120\uc554\uc744 \uce58\ub8cc\ud560 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud588\ub2e4\ub294 \uc5f0\uad6c\uac00 \ubcf4\uace0\ub410\ub2e4. 2025\ub144 12\uc6d4 23\uc77c \ubcf4\ub3c4\uc5d0 \ub530\ub974\uba74, \uc950 \uc2e4\ud5d8\uc5d0\uc11c FSP1 \uc720\uc804\uc790\uac00 \uacb0\ud54d\ub418\uac70\ub098 FSP1 \uc5b5\uc81c\uc81c(icFSP1)\ub97c \ud22c\uc5ec\ud558\uba74 \uc885\uc591 \ud06c\uae30\uac00 \uc904\uc5b4\ub4dc\ub294 \uacb0\uacfc\uac00 \ud655\uc778\ub410\ub2e4. \uc774 \uc5f0\uad6c\ub294 \ud559\uc220\uc9c0 Nature\uc5d0 \ubc1c\ud45c\ub41c \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc14\ud0d5\uc73c\ub85c \ud558\uba70, \uc5f0\uad6c\uc9c4 \uc18c\uc18d\uc740 NYU Langone Health\/NYU Grossman School of Medicine\uc774\ub2e4. \ube44\ud761\uc5f0\uc790 &#8230; <a title=\"\ud3d0 \uc120\uc554 \uce58\ub8cc\uc5d0 \ud6a8\uacfc\uc801\uc778 &#8216;FSP1 \uc5b5\uc81c\uc81c&#8217;\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/fsp1-inhibitor-lung-adenocarcinoma\/\" aria-label=\"\ud3d0 \uc120\uc554 \uce58\ub8cc\uc5d0 \ud6a8\uacfc\uc801\uc778 &#8216;FSP1 \uc5b5\uc81c\uc81c&#8217;\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":5291,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\ud3d0 \uc120\uc554 \uce58\ub8cc \uac00\ub2a5\uc131 \uc5f4\uc5b4\uc8fc\ub294 FSP1 \uc5b5\uc81c\uc81c \uc5f0\uad6c - \ud6c4\uc0dd\uc2e0\ubcf4","rank_math_description":"Nature \uae30\ubc18 \uc5f0\uad6c\uc5d0\uc11c FSP1 \uc5b5\uc81c\uac00 \uc950 \ubaa8\ub378\uc758 \ud3d0\uc120\uc554 \uc885\uc591\uc744 \uac10\uc18c\uc2dc\ucf30\ub2e4. icFSP1 \uc804\uc784\uc0c1 \uacb0\uacfc\uc640 \uc784\uc0c1 \uc801\uc6a9\uc744 \ub458\ub7ec\uc2fc \uc7a5\ub2e8\uc810\uacfc \ud5a5\ud6c4 \uacfc\uc81c\ub97c \uc815\ub9ac\ud55c\ub2e4.","rank_math_focus_keyword":"FSP1,\ud398\ub86d\ud1a0\uc2dc\uc2a4,\ud3d0\uc120\uc554,icFSP1,GPX4","footnotes":""},"categories":[2],"tags":[],"class_list":["post-5296","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/5296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=5296"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/5296\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/5291"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=5296"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=5296"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=5296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}