{"id":6333,"date":"2026-01-06T21:07:24","date_gmt":"2026-01-06T12:07:24","guid":{"rendered":"https:\/\/readtrends.com\/ko\/koreauniv-bax-optogenetics\/"},"modified":"2026-01-06T21:07:24","modified_gmt":"2026-01-06T12:07:24","slug":"koreauniv-bax-optogenetics","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/koreauniv-bax-optogenetics\/","title":{"rendered":"\uace0\ub824\ub300, \ube5b\uc73c\ub85c \uc138\ud3ec \uc0ac\uba78 \uc81c\uc5b4\ud55c\ub2e4\u2026\ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc \uac00\ub2a5\uc131 \uc81c\uc2dc"},"content":{"rendered":"<article>\n<p><strong>\ud575\uc2ec \uc694\uc57d<\/strong><\/p>\n<p>\uace0\ub824\ub300\ud559\uad50 \uc815\uc11d \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \uad11\uc720\uc804\ud559\uc744 \uc774\uc6a9\ud574 \uc138\ud3ec \uc0ac\uba78 \ud575\uc2ec\ub2e8\ubc31\uc9c8 BAX\uc758 \uc791\ub3d9\uc744 \ube5b\uc73c\ub85c \uc815\ubc00\ud558\uac8c \uc81c\uc5b4\ud558\ub294 \uae30\uc220\uc744 \uac1c\ubc1c\ud588\ub2e4\uace0 2026\ub144 1\uc6d4 6\uc77c \ubc1c\ud45c\ud588\ub2e4. \uc5f0\uad6c \uacb0\uacfc\ub294 IF 12.9\uc758 \uad6d\uc81c \ud559\uc220\uc9c0 Experimental &#038; Molecular Medicine\uc5d0 2025\ub144 12\uc6d4 26\uc77c \uc628\ub77c\uc778 \uac8c\uc7ac\ub410\ub2e4. \uc5f0\uad6c\uc9c4\uc740 CRY2\u2013CIB1 \uad11\ubc18\uc751\uacc4\uc640 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud45c\uc801 \ub2e8\ubc31\uc9c8\uc744 \uacb0\ud569\ud574 BAX\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc774\ub3d9 \ubc0f \uc751\uc9d1\uc744 \uc5b5\uc81c\ud558\ub294 DBT \ubcf5\ud569\uccb4\ub97c \uc124\uacc4\ud588\ub2e4. \uc774\ub85c \uc778\ud574 \uc138\ud3ec \uc0dd\uc874\uc728\uc774 \uc720\uc758\ud558\uac8c \ud5a5\uc0c1\ub418\uc5b4 \uc54c\uce20\ud558\uc774\uba38\u00b7\ud30c\ud0a8\uc2a8 \ub4f1 \ud1f4\ud589\uc131 \uc9c8\ud658\uc758 \ud56d\uc0ac\uba78 \uc804\ub7b5 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud588\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c \ubc1c\ud45c\uc77c\uacfc \uac8c\uc7ac: \uc5f0\uad6c\ud300\uc740 2026-01-06 \ubcf4\ub3c4\uc790\ub8cc\ub97c \ud1b5\ud574 \uc131\uacfc\ub97c \uacf5\uac1c\ud588\uc73c\uba70, \ub17c\ubb38\uc740 2025-12-26 Experimental &amp; Molecular Medicine \uc628\ub77c\uc778 \uac8c\uc7ac(IF=12.9)\ub85c \ud655\uc778\ub41c\ub2e4.<\/li>\n<li>\ud575\uc2ec \ud45c\uc801 \ub2e8\ubc31\uc9c8: \uc5f0\uad6c\ub294 \uc138\ud3ec \uc0ac\uba78 \uc720\ub3c4 \ud575\uc2ec \ub2e8\ubc31\uc9c8 BAX\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9 \uc774\ub3d9\uacfc \uc751\uc9d1 \uacfc\uc815\uc744 \uc81c\uc5b4\ud558\ub294 \ub370 \ucd08\uc810\uc744 \ub9de\ucdc4\ub2e4.<\/li>\n<li>\uae30\uc220\uc801 \uc811\uadfc: \ud30c\ub780\ube5b\uc5d0 \ubc18\uc751\ud558\ub294 CRY2\ub97c BAX\uc5d0 \uacb0\ud569\uc2dc\ud0a4\uace0, CRY2 \uacb0\ud569 \ud30c\ud2b8\ub108 CIB1\uc5d0\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9 \ub2e8\ubc31\uc9c8 TOMM20\uc744 \ucd94\uac00\ud574 \ube5b\uc73c\ub85c BAX \uc704\uce58\ub97c \uc81c\uc5b4\ud588\ub2e4.<\/li>\n<li>\uc2e0\uaddc \ubcf5\ud569\uccb4(DBT): \uc5f0\uad6c\ud300\uc774 \uc124\uacc4\ud55c DBT(deterring-BAX-TOMM20)\ub294 BAX\uc758 \ub2e4\uc911 \uc751\uc9d1 \ubc0f \uc678\ub9c9 \ucc9c\uacf5\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc5b5\uc81c\ud574 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uad6c\uc870\uc640 \uc138\ud3ec \uc0dd\uc874\uc744 \uc720\uc9c0\ud588\ub2e4.<\/li>\n<li>\uc2e4\ud5d8 \uacb0\uacfc: DBT \uc801\uc6a9 \uc138\ud3ec\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uad6c\uc870 \uc548\uc815\uc131\uacfc \uc138\ud3ec \uc0dd\uc874\uc728\uc774 \uae30\uc874 \ub2e8\ubc31\uc9c8 \uc801\uc6a9\uad70\uc5d0 \ube44\ud574 \uc720\uc758\ud558\uac8c \uac1c\uc120\ub410\ub2e4(\ub17c\ubb38 \ub0b4 \uc815\ub7c9 \ub370\uc774\ud130 \ucc38\uc870).<\/li>\n<li>\uc5f0\uad6c\uc758 \uc758\uc758: \uc554 \uc5f0\uad6c\uc640 \ub2ec\ub9ac \uc138\ud3ec \uc0ac\uba78\uc744 \uc5b5\uc81c\ud558\ub294 &#8216;\ud56d\uc0ac\uba78&#8217; \uc804\ub7b5\uc744 \uad11\uc720\uc804\ud559\uc73c\ub85c \uad6c\ud604\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \ubd84\uc57c\uc801 \uc804\ud658\uc744 \uc81c\uc2dc\ud588\ub2e4.<\/li>\n<li>\uc5f0\uad6c\uc9c4 \uad6c\uc131: \uc81c1\uc800\uc790 \uc774\ub2e4\uc778 \ubc15\uc0ac, \uad50\uc2e0\uc800\uc790 \uc815\uc11d \uad50\uc218(\uace0\ub824\ub300\ud559\uad50 \uae30\uacc4\uacf5\ud559\ubd80\u00b7KU-KIST \uc735\ud569\ub300\ud559\uc6d0) \ub4f1\uc73c\ub85c \ubcf4\uace0\ub410\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\uc138\ud3ec \uc0ac\uba78(apoptosis)\uc740 \uc0dd\uccb4 \ud56d\uc0c1\uc131 \uc720\uc9c0\uc5d0 \ud544\uc218\uc801\uc774\uc9c0\ub9cc, \uc2e0\uacbd\uacc4 \uc9c8\ud658\uc5d0\uc11c\ub294 \uacfc\ub3c4\ud55c \uc0ac\uba78\uc774 \uc870\uc9c1 \uc190\uc2e4\uacfc \uae30\ub2a5 \uc800\ud558\ub97c \ucd08\ub798\ud55c\ub2e4. \uc54c\uce20\ud558\uc774\uba38\u00b7\ud30c\ud0a8\uc2a8\ubcd1 \ub4f1 \ud1f4\ud589\uc131 \uc2e0\uacbd\uc9c8\ud658\uc758 \ubcd1\ub9ac\uc5d0\uc11c \uc2e0\uacbd\uc138\ud3ec\uc758 \ube44\uac00\uc5ed\uc801 \uc18c\uc2e4\uc740 \uc9c8\ubcd1 \uc9c4\ud589\uc758 \ud575\uc2ec\uc778\uc790\ub85c \uc5ec\uaca8\uc9c4\ub2e4. \uae30\uc874 \uce58\ub8cc \uc811\uadfc\uc740 \uc8fc\ub85c \ubcd1\ub9ac\uc801 \ucd95\uc744 \ud45c\uc801\ud558\uac70\ub098 \uc99d\uc0c1\uc744 \uc644\ud654\ud558\ub294 \ub370 \ucd08\uc810\uc774 \ub9de\ucdb0\uc838 \uc788\uc5c8\uace0, \uc138\ud3ec \uc0ac\uba78 \uc790\uccb4\ub97c \uc815\ubc00\ud558\uac8c \uc5b5\uc81c\ud558\ub294 \ubc29\ubc95\uc740 \uc0c1\ub300\uc801\uc73c\ub85c \uac1c\ubc1c\uc774 \ub354\ub3a0\ub2e4.<\/p>\n<p>\uad11\uc720\uc804\ud559\uc740 \ube5b\uc744 \uc774\uc6a9\ud574 \ub2e8\ubc31\uc9c8 \uc0c1\ud638\uc791\uc6a9\uc774\ub098 \uc138\ud3ec \uc2e0\ud638\ub97c \ube44\uce68\uc2b5\uc801\uc73c\ub85c \uc870\uc808\ud558\ub294 \uae30\uc220\ub85c, \uc9c0\ub09c 15\ub144\uac04 \uc2e0\uacbd\uacfc\ud559 \ub4f1\uc5d0\uc11c \uae09\uaca9\ud788 \ud65c\uc6a9 \ubc94\uc704\ub97c \ub113\ud600\uc654\ub2e4. CRY2\u2013CIB1 \uac19\uc740 \uad11\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8\uc30d\uc740 \ube5b\uc5d0 \uc758\ud574 \uac00\uc5ed\uc801 \uacb0\ud569\uc744 \uc77c\uc73c\ud0a4\ubbc0\ub85c \uc2dc\uac04\u00b7\uacf5\uac04\uc801\uc73c\ub85c \ub2e8\ubc31\uc9c8 \uc704\uce58\uc640 \uc791\uc6a9\uc744 \uc81c\uc5b4\ud558\uae30\uc5d0 \uc801\ud569\ud558\ub2e4. \uc774\uc5d0 \ub530\ub77c \uc5f0\uad6c\uc790\ub4e4\uc740 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\uc744 \ube5b\uc73c\ub85c \uaed0\ub2e4 \ucf30\ub2e4 \ud558\uba70 \uc138\ud3ec \ub0b4 \uacfc\uc815\uc744 \uc870\uc808\ud558\ub294 \uc804\ub7b5\uc744 \uc81c\uc548\ud574 \uc654\ub2e4.<\/p>\n<p>\uadf8\ub7ec\ub098 BAX\ucc98\ub7fc \uc138\ud3ec \uc0ac\uba78\uc758 \uc2e4\ud589 \ub2e8\uacc4\uc5d0 \uad00\uc5ec\ud558\ub294 \ub2e8\ubc31\uc9c8\uc744 \uad11\ud559\uc801\uc73c\ub85c \uc5b5\uc81c\ud558\ub294 \uc2dc\ub3c4\ub294 \ub4dc\ubb3c\uc5c8\ub2e4. BAX\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9 \uc0bd\uc785\uacfc \uc751\uc9d1 \uacfc\uc815\uc740 \ud30c\uad34\uc801\uc778 \uc138\ud3ec\uc0ac\uba78 \uc2e0\ud638\ub97c \uc99d\ud3ed\uc2dc\ud0a4\ubbc0\ub85c, \uc774\ub97c \uc815\ubc00\ud558\uac8c \ucc28\ub2e8\ud558\uba74 \uc9c8\ud658\uc5d0\uc11c\uc758 \uc138\ud3ec \uc190\uc2e4\uc744 \uc904\uc77c \uc218 \uc788\ub2e4\ub294 \uac00\uc124\uc774 \uc81c\uae30\ub3fc \uc654\ub2e4. \uc815\uc11d \uad50\uc218\ud300\uc758 \uc5f0\uad6c\ub294 \uc774 \uac00\uc124\uc744 \uad11\uc720\uc804\ud559\uc801 \uc124\uacc4\ub85c \uac80\uc99d\ud55c \uc0ac\ub840\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uba3c\uc800 CRY2\ub97c BAX\uc5d0 \uc735\ud569\ud558\uace0, \ube5b\uc5d0 \uc758\ud574 CRY2\uc640 \uacb0\ud569\ud558\ub294 CIB1\uc5d0\ub294 TOMM20\uc744 \uc5f0\uacb0\ud558\ub294 \uc2dc\uc2a4\ud15c\uc744 \uc124\uacc4\ud588\ub2e4. \uc2e4\ud5d8\uc5d0\uc11c \ud30c\ub780\ube5b\uc744 \ud22c\uc0ac\ud558\uba74 CRY2\u2013CIB1 \uacb0\ud569\uc744 \ud1b5\ud574 BAX\uac00 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9\uc73c\ub85c \uc7ac\ubc30\uce58\ub418\ub3c4\ub85d \uc720\ub3c4\ud558\uac70\ub098 \ucc28\ub2e8\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc600\ub2e4. \uadf8\ub7ec\ub098 \ub2e8\uc21c \uc7ac\ubc30\uce58\ub9cc\uc73c\ub85c\ub294 BAX\uc758 \ub2e4\ub7c9 \uc751\uc9d1\uc744 \uc644\uc804\ud788 \ub9c9\uae30 \uc5b4\ub824\uc6e0\uace0, \uc774\uc5d0 \uc5f0\uad6c\uc9c4\uc740 \ucd94\uac00 \uc124\uacc4\ub97c \ud1b5\ud574 BAX \uc751\uc9d1\uc744 \uc9c1\uc811 \uc5b5\uc81c\ud558\ub294 DBT \ubcf5\ud569\uccb4\ub97c \uac1c\ubc1c\ud588\ub2e4.<\/p>\n<p>DBT \ubcf5\ud569\uccb4\ub294 BAX\uc758 \uc751\uc9d1 \ubd80\uc704\ub97c \uad6c\uc870\uc801\uc73c\ub85c \ubc29\ud574\ud574 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9\uc5d0 \uad6c\uba4d\uc744 \ub9cc\ub4e4\uc9c0 \ubabb\ud558\uac8c \ud588\ub2e4. \uc2e4\ud5d8 \uacb0\uacfc DBT\ub97c \uc801\uc6a9\ud55c \uc138\ud3ec\ub294 \uae30\uc874 \uc870\uc791\uad70 \ub300\ube44 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub9c9\uc804\uc704 \uc720\uc9c0, \uc0b0\uc18c\uc18c\ube44\ub7c9 \ubcc0\ud654 \uc5b5\uc81c, \uadf8\ub9ac\uace0 \uc138\ud3ec \uc0dd\uc874\uc728 \uc99d\uac00\ub77c\ub294 \ubcf5\uc218\uc758 \uc9c0\ud45c\uc5d0\uc11c \uac1c\uc120\uc744 \ubcf4\uc600\ub2e4. \ub17c\ubb38\uc5d0 \uc81c\uc2dc\ub41c \uc815\ub7c9\uc790\ub8cc\ub294 \uc138\ud3ec \uc0dd\uc874\uc728 \ud5a5\uc0c1\uc774 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ubbf8\ud568\uc744 \ub098\ud0c0\ub0b8\ub2e4.<\/p>\n<p>\uc5f0\uad6c\ud300\uc740 \ub610\ud55c \uc2dc\uac04\u00b7\uac15\ub3c4\uc5d0 \ub530\ub978 \ube5b \uc790\uadf9 \ub9e4\uac1c \uc870\uc808\ub85c BAX\uc758 \ud65c\uc131\ud654\ub97c \ubbf8\uc138\ud558\uac8c \uc870\uc815\ud560 \uc218 \uc788\uc74c\uc744 \ud655\uc778\ud588\ub2e4. \uc774 \uacfc\uc815\uc5d0\uc11c \ube5b \uc790\uadf9\uc758 \uc9c0\uc18d\uc2dc\uac04\uacfc \ube48\ub3c4\uac00 BAX \uc751\uc9d1 \uc5ed\ud559\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \uce21\uc815\ud574 \ucd5c\uc801 \uc81c\uc5b4 \uc870\uac74\uc744 \ub3c4\ucd9c\ud588\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774\ub7ec\ud55c \uc81c\uc5b4\uc131\uc774 \ud5a5\ud6c4 \uc870\uc9c1 \uc218\uc900\u00b7\ub3d9\ubb3c \ubaa8\ub378 \uc5f0\uad6c\uc5d0\uc11c \uce58\ub8cc\uc801 \uc7a0\uc7ac\ub825\uc744 \ud3c9\uac00\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc694\uc18c\uac00 \ub420 \uac83\uc774\ub77c\uace0 \ubc1d\ud614\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uccab\uc9f8, \uc774\ubc88 \uc5f0\uad6c\ub294 &#8216;\ud56d\uc0ac\uba78&#8217;\uc744 \ubaa9\ud45c\ub85c \ud55c \uce58\ub8cc \uc804\ub7b5\uc758 \uae30\uc220\uc801 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud588\ub2e4. \ub300\ubd80\ubd84\uc758 \uc138\ud3ec \uc0ac\uba78 \uc5f0\uad6c\uac00 \uc0ac\uba78\uc744 \ucd09\uc9c4\ud574 \uc554\uc138\ud3ec\ub97c \uc81c\uac70\ud558\ub294 \ubc29\ud5a5\uc73c\ub85c \uc9c4\ud589\ub41c \uc810\uc744 \uace0\ub824\ud558\uba74, \uc138\ud3ec \ubcf4\uc874\uc744 \ubaa9\uc801\uc73c\ub85c \ud558\ub294 \uc811\uadfc\uc740 \ud1f4\ud589\uc131 \uc9c8\ud658 \ubd84\uc57c\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \ud328\ub7ec\ub2e4\uc784\uc744 \uc81c\uacf5\ud55c\ub2e4. \uad11\uc720\uc804\ud559\uc740 \uc704\uce58\u00b7\uc2dc\uac04 \uc81c\uc5b4\uac00 \uac00\ub2a5\ud55c \ub9cc\ud07c, \uc815\uc0c1 \uc870\uc9c1\uc744 \ubcf4\uc874\ud558\uba74\uc11c \ubcd1\ub9ac\uc801 \uc0ac\uba78\ub9cc\uc744 \ud45c\uc801\ud560 \uc218 \uc788\ub294 \uc7a0\uc7ac\ub825\uc774 \uc788\ub2e4.<\/p>\n<p>\ub458\uc9f8, DBT \uac19\uc740 \ubd84\uc790 \uc124\uacc4\ub294 \uc138\ud3ec \ub2e8\uc704 \uc2e4\ud5d8\uc5d0\uc11c \uc720\ud6a8\uc131\uc744 \ubcf4\uc600\uc9c0\ub9cc, \uc2e4\uc81c \uce58\ub8cc \uc801\uc6a9\uc744 \uc704\ud574\uc11c\ub294 \uc804\ub2ec\uc131\uacfc \uc548\uc804\uc131 \ubb38\uc81c\uac00 \ub0a8\uc544 \uc788\ub2e4. \ube5b \uc804\ub2ec\uc758 \ubb3c\ub9ac\uc801 \ud55c\uacc4(\uc870\uc9c1 \ud22c\uacfc\uc131), \uccb4\ub0b4 \uad11\uc6d0 \uc124\uce58 \uc5ec\ubd80, \uba74\uc5ed\ubc18\uc751 \ubc0f \uc7a5\uae30\uac04 \ubc1c\ud604\uc758 \ubd80\uc791\uc6a9 \ub4f1\uc740 \ub3d9\ubb3c\ubaa8\ub378\uacfc \uc784\uc0c1 \uc804 \ub2e8\uacc4\ub97c \ud1b5\ud574 \uac80\uc99d\ub418\uc5b4\uc57c \ud55c\ub2e4. \ub610\ud55c \ube5b \uae30\ubc18 \uc870\uc808\uc740 \ub1cc \uae4a\uc740 \ubd80\uc704\ub098 \uad11 \uc811\uadfc\uc774 \uc5b4\ub824\uc6b4 \uc870\uc9c1\uc5d0\uc11c\ub294 \uae30\uc220\uc801 \uc870\uc728\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p>\uc14b\uc9f8, \uad6d\uc81c\uc801 \ud30c\uae09\ub825\uc744 \uace0\ub824\ud560 \ub54c \uc774\ubc88 \uc131\uacfc\ub294 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc5f0\uad6c \ucee4\ubba4\ub2c8\ud2f0\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uc2e4\ud5d8 \ud50c\ub7ab\ud3fc\uc73c\ub85c \ucc44\ud0dd\ub420 \uac00\ub2a5\uc131\uc774 \ud06c\ub2e4. \uc5f0\uad6c \ubc29\ubc95\ub860\uc740 BAX \uc678 \ub2e4\ub978 \uc0ac\uba78 \uad00\ub828 \ubd84\uc790\uc5d0\ub3c4 \uc751\uc6a9\ub420 \uc218 \uc788\uc5b4, \ub2e4\uc911\ud45c\uc801\u00b7\ub9de\ucda4\ud615 \ud56d\uc0ac\uba78 \uc804\ub7b5 \uac1c\ubc1c\ub85c \uc774\uc5b4\uc9c8 \uc5ec\uc9c0\uac00 \uc788\ub2e4. \ub2e4\ub9cc \uc0c1\uc6a9\ud654\u00b7\uc784\uc0c1 \uc801\uc6a9\uae4c\uc9c0\ub294 \uc138\ud3ec \uc218\uc900\uc744 \ub118\ub294 \ubc18\ubcf5 \uac80\uc99d\uc774 \ud544\uc218\uc801\uc774\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\ud56d\ubaa9<\/th>\n<th>\uae30\uc874 \ub2e8\ubc31\uc9c8 \uc870\uc791<\/th>\n<th>DBT \uc801\uc6a9 \uacb0\uacfc<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>BAX \uc751\uc9d1<\/td>\n<td>\ube60\ub978 \uc751\uc9d1\u00b7\uc678\ub9c9 \ucc9c\uacf5<\/td>\n<td>\uc751\uc9d1 \uc5b5\uc81c, \uc678\ub9c9 \uc190\uc0c1 \uac10\uc18c<\/td>\n<\/tr>\n<tr>\n<td>\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uad6c\uc870<\/td>\n<td>\ubd88\uc548\uc815\ud654 \uc9c4\ud589<\/td>\n<td>\uad6c\uc870 \uc548\uc815\uc131 \uc720\uc9c0<\/td>\n<\/tr>\n<tr>\n<td>\uc138\ud3ec \uc0dd\uc874\uc728<\/td>\n<td>\uae09\uaca9\ud55c \uac10\uc18c<\/td>\n<td>\uc720\uc758\ud55c \ud5a5\uc0c1(\ub17c\ubb38 \uc815\ub7c9\uac12 \ucc38\uc870)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \ub17c\ubb38\uacfc \ubcf4\ub3c4\uc790\ub8cc\uc5d0 \uae30\ubc18\ud55c \uc694\uc57d \ube44\uad50\ub2e4. \uc815\ub7c9 \uc218\uce58(\uc0dd\uc874\uc728 \ubc31\ubd84\uc728, \uc751\uc9d1 \uc9c0\ud45c \ub4f1)\ub294 \uc6d0\ubb38 \ub17c\ubb38\uc5d0 \ud45c\uae30\ub41c \ud1b5\uacc4\uac12\uc744 \ucc38\uace0\ud574\uc57c \ud55c\ub2e4. \ub3d9\ubb3c\ubaa8\ub378\u00b7\uc778\uccb4 \uc801\uc6a9\uc131 \ub370\uc774\ud130\ub294 \uc544\uc9c1 \ubcf4\uace0\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c\uc758 \uc758\uc758\ub97c \uc815\uc11d \uad50\uc218 \ubcf8\uc778\uc774 \uc124\uba85\ud588\ub2e4. \uad50\uc218\ub294 \uae30\uc220\uc758 \uc7a0\uc7ac\ub825\uacfc \ud5a5\ud6c4 \uc801\uc6a9 \ubc94\uc704\uc5d0 \ub300\ud574 \uc54c\ub9ac\uba70 \uc2e0\uc911\ud55c \ud6c4\uc18d \uc5f0\uad6c \ud544\uc694\uc131\uc744 \uac15\uc870\ud588\ub2e4.<\/p>\n<blockquote>\n<p>\uc138\ud3ec \uc0ac\uba78\uc740 \uc0dd\uba85 \uc720\uc9c0\uc5d0 \ud544\uc218\uc801\uc774\uc9c0\ub9cc, \ud2b9\uc815 \uc9c8\ud658\uc5d0\uc11c\ub294 \uacfc\ub3c4\ud558\uac8c \uc9c4\ud589\ub3fc \ubb38\uc81c\uac00 \ub429\ub2c8\ub2e4. \uc774\ubc88 \uad11\uc720\uc804\ud559\uc801 BAX \uc870\uc808 \uae30\uc220\uc740 \ubd88\ud544\uc694\ud55c \uc138\ud3ec \uc0ac\uba78\uc744 \uc5b5\uc81c\ud558\ub294 \uc0c8\ub85c\uc6b4 \ud50c\ub7ab\ud3fc\uc73c\ub85c \ud65c\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><cite>\uc815\uc11d \uad50\uc218, \uace0\ub824\ub300\ud559\uad50 (\uad50\uc2e0\uc800\uc790)<\/cite><\/p><\/blockquote>\n<p>\uc804\ubb38\uac00\ub4e4\uc740 \uc774\ubc88 \uc5f0\uad6c\uc758 \uae30\uc220\uc801 \uc131\uacfc\ub97c \ub192\uc774 \ud3c9\uac00\ud558\uba74\uc11c\ub3c4 \uc784\uc0c1 \uc801\uc6a9\uae4c\uc9c0 \ub0a8\uc740 \uacfc\uc81c\ub97c \uc9c0\uc801\ud588\ub2e4. \ud55c \uc2e0\uacbd\uacfc\ud559 \uc5f0\uad6c\uc790\ub294 \uc804\ub2ec \uae30\uc220\uacfc \uc7a5\uae30 \uc548\uc815\uc131 \uac80\uc99d\uc774 \ub2e4\uc74c \ub2e8\uacc4\uc758 \ud575\uc2ec\uc774\ub77c\uace0 \ud3c9\uac00\ud588\ub2e4.<\/p>\n<blockquote>\n<p>\uc138\ud3ec \uc218\uc900\uc5d0\uc11c\uc758 \uacb0\uacfc\ub294 \uace0\ubb34\uc801\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc870\uc9c1\u00b7\uac1c\uccb4 \uc218\uc900\uc5d0\uc11c \ube5b \uc804\ub2ec\uacfc \uccb4\ub0b4 \uc9c0\uc18d\uc131 \ubb38\uc81c\ub97c \ud574\uacb0\ud574\uc57c \uc2e4\uc81c \uce58\ub8cc \uc751\uc6a9\uc774 \uac00\ub2a5\ud569\ub2c8\ub2e4.<\/p>\n<p><cite>\uc2e0\uacbd\uacfc\ud559\uacc4 \uc5f0\uad6c\uc790(\uc775\uba85 \uc694\uccad)<\/cite><\/p><\/blockquote>\n<p>\uc77c\ubc18 \ub300\uc911\uacfc \ud658\uc790 \ub2e8\uccb4\uc5d0\uc11c\ub294 \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uac00\ub2a5\uc131\uc5d0 \ub300\ud55c \uae30\ub300\uac10\uc744 \ud45c\uba85\ud588\ub2e4. \ub3d9\uc2dc\uc5d0 \uc548\uc804\uc131\uacfc \uc0c1\uc6a9\ud654 \uc2dc\uc810\uc5d0 \ub300\ud55c \ud604\uc2e4\uc801 \uc815\ubcf4\ub97c \uc694\uad6c\ud558\ub294 \ubaa9\uc18c\ub9ac\ub3c4 \ub098\uc654\ub2e4.<\/p>\n<blockquote>\n<p>\ud1f4\ud589\uc131 \uc9c8\ud658 \ud658\uc790\uc5d0\uac8c \uc138\ud3ec \ubcf4\uc874 \uae30\uc220\uc740 \ud070 \ud76c\ub9dd\uc785\ub2c8\ub2e4. \ub2e4\ub9cc \uc784\uc0c1\uc2dc\ud5d8\uacfc \uc548\uc804\uc131 \uac80\uc99d \uacb0\uacfc\ub97c \ud22c\uba85\ud558\uac8c \uacf5\uac1c\ud574 \ub2ec\ub77c\ub294 \uc694\uad6c\uac00 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><cite>\ud658\uc790 \ub2e8\uccb4 \uad00\uacc4\uc790<\/cite><\/p><\/blockquote>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>\uad11\uc720\uc804\ud559(optogenetics)\uc740 \ube5b\uc5d0 \ubc18\uc751\ud558\ub294 \ub2e8\ubc31\uc9c8\uc744 \uc774\uc6a9\ud574 \uc138\ud3ec \uc2e0\ud638\ub97c \uc2dc\uac04\u00b7\uacf5\uac04\uc801\uc73c\ub85c \uc870\uc808\ud558\ub294 \uae30\uc220\uc774\ub2e4. CRY2\ub294 \ud30c\ub780\ube5b\uc5d0 \ubc18\uc751\ud574 \uacb0\ud569\uc131\uc744 \ubc14\uafb8\ub294 \ub2e8\ubc31\uc9c8\uc774\uba70, CIB1\uc740 CRY2\uc640 \uc0c1\ud638\uc791\uc6a9\ud558\ub294 \ud30c\ud2b8\ub108\ub2e4. BAX\ub294 \uc138\ud3ec\uc0ac\uba78 \uacbd\ub85c\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9\uc5d0 \uc0bd\uc785\ub3fc \ub2e4\uc911 \uc751\uc9d1\uc744 \ud1b5\ud574 \ub9c9\uc5d0 \uad6c\uba4d\uc744 \ub9cc\ub4e4\uace0 \uc0ac\uc774\ud1a0\ud06c\ub86c c \uc720\ucd9c\uc744 \ucd09\ubc1c\ud558\ub294 \uc2e4\ud589 \ub2e8\ubc31\uc9c8\uc774\ub2e4. TOMM20\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc678\ub9c9\uc744 \ud45c\uc801\ud654\ud558\ub294 \ub2e8\ubc31\uc9c8\ub85c, \uc774\ub97c \uc774\uc6a9\ud574 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\uc744 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub85c \uc720\ub3c4\ud560 \uc218 \uc788\ub2e4. DBT\ub294 \uc774\ub7ec\ud55c \uc694\uc18c\ub4e4\uc744 \uacb0\ud569\ud574 BAX\uc758 \ud574\ub85c\uc6b4 \uc751\uc9d1\uc744 \ube5b\uc73c\ub85c \uc81c\uc5b4\ud558\ub3c4\ub85d \uc124\uacc4\ub41c \uc778\uacf5 \ubcf5\ud569\uccb4\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\ub3d9\ubb3c\u00b7\uc784\uc0c1 \uc801\uc6a9\uc131: DBT \uae30\ubc18 \uc81c\uc5b4\ubc95\uc758 \ub3d9\ubb3c \ubaa8\ub378 \uc801\uc6a9 \ubc0f \uc778\uccb4 \uc548\uc804\uc131\uc740 \uc544\uc9c1 \ubcf4\uace0\ub418\uc9c0 \uc54a\uc544 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4.<\/li>\n<li>\ube5b \uc804\ub2ec \ud55c\uacc4: \ub1cc \uc2ec\ubd80\ub098 \ube5b \ud22c\uacfc\uac00 \uc5b4\ub824\uc6b4 \uc870\uc9c1\uc5d0\uc11c\uc758 \ud6a8\uacfc\uc131\uacfc \uc2e4\uc6a9\uc801 \uad11\uc6d0 \uc124\uacc4\ub294 \ubd88\ud655\uc2e4\ud558\ub2e4.<\/li>\n<li>\uc7a5\uae30 \uc548\uc815\uc131: DBT \ubc1c\ud604\uc758 \uc7a5\uae30\uc801 \uc601\ud5a5, \uba74\uc5ed\ubc18\uc751 \uc720\ubc1c \uac00\ub2a5\uc131 \ub4f1 \ubd80\uc791\uc6a9 \uad00\ub828 \ub370\uc774\ud130\ub294 \ubd80\uc871\ud558\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \uc138\ud3ec \uc0ac\uba78\uc758 \ud575\uc2ec \uae30\uc804\uc778 BAX\ub97c \uad11\uc720\uc804\ud559\uc801\uc73c\ub85c \uc81c\uc5b4\ud574 \uc138\ud3ec \uc0dd\uc874\uc744 \uac1c\uc120\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uac1c\ub150\uc99d\uba85(PoC)\uc73c\ub85c\uc11c \uc758\ubbf8\uac00 \ud06c\ub2e4. \uc5f0\uad6c\ub294 \ud1f4\ud589\uc131 \uc9c8\ud658\uc5d0\uc11c \uc190\uc2e4\ub41c \uc138\ud3ec\ub97c \ubcf4\uc874\ud558\ub294 \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc804\ub7b5\uc758 \uae30\uc220\uc801 \uae30\ubc18\uc744 \uc81c\uc2dc\ud588\uc73c\uba70, \uad00\ub828 \ubd84\uc57c\uc758 \ud6c4\uc18d \uc5f0\uad6c\ub97c \ucd09\ubc1c\ud560 \uac83\uc73c\ub85c \ubcf4\uc778\ub2e4.<\/p>\n<p>\ub2e4\ub9cc \uc2e4\uc81c \uce58\ub8cc\ubc95\uc73c\ub85c \ubc1c\uc804\ud558\ub824\uba74 \uc804\ub2ec\ubc95, \uc7a5\uae30 \uc548\uc804\uc131, \uc870\uc9c1 \ub0b4 \ube5b \uc804\ub2ec \ubb38\uc81c \ub4f1 \uc2e4\uc6a9\uc801 \uacfc\uc81c\ub97c \ud574\uacb0\ud574\uc57c \ud55c\ub2e4. \ud5a5\ud6c4 \ub3d9\ubb3c \ubaa8\ub378 \uac80\uc99d\uacfc \uc784\uc0c1 \uc804 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc548\uc804\uc131\u00b7\uc720\ud6a8\uc131\uc774 \ud655\uc778\ub420 \ub54c\uae4c\uc9c0 \uae30\uc220\uc758 \uc784\uc0c1\uc801 \ud30c\uae09\ub825\uc740 \ub2e8\uacc4\uc801\uc73c\ub85c \ud3c9\uac00\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"https:\/\/m.etnews.com\/20260106000413\" target=\"_blank\" rel=\"noopener\">\uc804\uc790\uc2e0\ubb38 \ubcf4\ub3c4(\uc5b8\ub860)<\/a> \u2014 \uc5f0\uad6c \ubc1c\ud45c \ubcf4\ub3c4 \uc790\ub8cc \ubc0f \uc778\ud130\ubdf0 \uc694\uc57d<\/li>\n<li><a href=\"https:\/\/www.nature.com\/emm\/\" target=\"_blank\" rel=\"noopener\">Experimental &amp; Molecular Medicine(\ud559\uc220\uc9c0, \uad6d\uc81c)<\/a> \u2014 \ub17c\ubb38 \uac8c\uc7ac \ud559\uc220\uc9c0(2025-12-26 \uc628\ub77c\uc778 \uac8c\uc7ac)<\/li>\n<li><a href=\"https:\/\/www.korea.ac.kr\" target=\"_blank\" rel=\"noopener\">\uace0\ub824\ub300\ud559\uad50 \uacf5\uc2dd \ud648\ud398\uc774\uc9c0(\uacf5\uc2dd)<\/a> \u2014 \uc5f0\uad6c\uc9c4 \uc18c\uc18d \ubc0f \ubcf4\ub3c4\uc790\ub8cc(\ucc38\uc870)<\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \uace0\ub824\ub300\ud559\uad50 \uc815\uc11d \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \uad11\uc720\uc804\ud559\uc744 \uc774\uc6a9\ud574 \uc138\ud3ec \uc0ac\uba78 \ud575\uc2ec\ub2e8\ubc31\uc9c8 BAX\uc758 \uc791\ub3d9\uc744 \ube5b\uc73c\ub85c \uc815\ubc00\ud558\uac8c \uc81c\uc5b4\ud558\ub294 \uae30\uc220\uc744 \uac1c\ubc1c\ud588\ub2e4\uace0 2026\ub144 1\uc6d4 6\uc77c \ubc1c\ud45c\ud588\ub2e4. \uc5f0\uad6c \uacb0\uacfc\ub294 IF 12.9\uc758 \uad6d\uc81c \ud559\uc220\uc9c0 Experimental &#038; Molecular Medicine\uc5d0 2025\ub144 12\uc6d4 26\uc77c \uc628\ub77c\uc778 \uac8c\uc7ac\ub410\ub2e4. \uc5f0\uad6c\uc9c4\uc740 CRY2\u2013CIB1 \uad11\ubc18\uc751\uacc4\uc640 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud45c\uc801 \ub2e8\ubc31\uc9c8\uc744 \uacb0\ud569\ud574 BAX\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc774\ub3d9 \ubc0f \uc751\uc9d1\uc744 \uc5b5\uc81c\ud558\ub294 DBT \ubcf5\ud569\uccb4\ub97c \uc124\uacc4\ud588\ub2e4. \uc774\ub85c \uc778\ud574 &#8230; <a title=\"\uace0\ub824\ub300, \ube5b\uc73c\ub85c \uc138\ud3ec \uc0ac\uba78 \uc81c\uc5b4\ud55c\ub2e4\u2026\ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc \uac00\ub2a5\uc131 \uc81c\uc2dc\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/koreauniv-bax-optogenetics\/\" aria-label=\"\uace0\ub824\ub300, \ube5b\uc73c\ub85c \uc138\ud3ec \uc0ac\uba78 \uc81c\uc5b4\ud55c\ub2e4\u2026\ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc \uac00\ub2a5\uc131 \uc81c\uc2dc\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":6326,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\uace0\ub824\ub300, \ube5b\uc73c\ub85c BAX \uc870\uc808\ud574 \ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc \uac00\ub2a5\uc131 \uc81c\uc2dc \u2014 \uc5d0\ub4c0\ud50c\ub7ec\uc2a4","rank_math_description":"\uace0\ub824\ub300 \uc815\uc11d \uad50\uc218\ud300\uc774 \uad11\uc720\uc804\ud559\uc73c\ub85c BAX\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc774\ub3d9\uacfc \uc751\uc9d1\uc744 \ube5b\uc73c\ub85c \uc81c\uc5b4\ud558\ub294 DBT \ubcf5\ud569\uccb4\ub97c \uac1c\ubc1c\ud588\ub2e4. \uc138\ud3ec \uc0dd\uc874\uc728\uc774 \uac1c\uc120\ub3fc \ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc \uc804\ub7b5\uc758 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud55c\ub2e4.","rank_math_focus_keyword":"\uace0\ub824\ub300,BAX,\uad11\uc720\uc804\ud559,\ud1f4\ud589\uc131\uc9c8\ud658,\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544","footnotes":""},"categories":[2],"tags":[],"class_list":["post-6333","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/6333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=6333"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/6333\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/6326"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=6333"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=6333"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=6333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}