{"id":7419,"date":"2026-01-27T07:08:01","date_gmt":"2026-01-26T22:08:01","guid":{"rendered":"https:\/\/readtrends.com\/ko\/tremfya-stelara-psoriasis\/"},"modified":"2026-01-27T07:08:01","modified_gmt":"2026-01-26T22:08:01","slug":"tremfya-stelara-psoriasis","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/tremfya-stelara-psoriasis\/","title":{"rendered":"\ud2b8\ub818\ud53c\uc5b4 vs \uc2a4\ud154\ub77c\ub77c, \uc911\uc99d \uac74\uc120\uc11c &#8216;\uc11c\ub85c \ub2e4\ub978&#8217; \uac15\uc810 &#8211; \uba54\ub514\uce7c\uc5c5\uc800\ubc84"},"content":{"rendered":"<article>\n<h2>\ud575\uc2ec \uc694\uc57d<\/h2>\n<p>\uacbd\ubd81\ub300\ubcd1\uc6d0 \uc7a5\uc6a9\ud604 \uad50\uc218\ud300\uc774 \ub300\ud55c\ud53c\ubd80\uacfc\ud559\ud68c\uc9c0 Annals of Dermatology\uc5d0 \ubc1c\ud45c\ud55c \uad6d\ub0b4 \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5 \ubd84\uc11d(2013-01~2022-07, \ud658\uc790 108\uba85)\uc740 \ud2b8\ub818\ud53c\uc5b4(\uad6c\uc140\ucfe0\ub9d9, 74\uba85)\uc640 \uc2a4\ud154\ub77c\ub77c(\uc6b0\uc2a4\ud14c\ud0a4\ub204\ub9d9, 34\uba85)\uc758 \uc911\uc99d \uac74\uc120 \uce58\ub8cc \uacb0\uacfc\ub97c \ube44\uad50\ud588\ub2e4. 28\uc8fc \ud3c9\uac00 \uc2dc \ud2b8\ub818\ud53c\uc5b4\ub294 \ud53c\ubd80 \ubcd1\ubcc0 \uac1c\uc120(PASI \uac10\uc18c)\uc5d0\uc11c \ud1b5\uacc4\uc801\uc73c\ub85c \ub354 \uc6b0\uc218\ud588\uace0(P=0.040), \uc2a4\ud154\ub77c\ub77c\ub294 \uac00\ub824\uc6c0\uc99d(NRS \ubcc0\ud654) \uc644\ud654 \ud3ed\uc774 \ub354 \ucef8\ub2e4(P=0.033). \uc5f0\uad6c\ub294 \ud658\uc790 \uc0b6\uc758 \uc9c8\uacfc \ubc00\uc811\ud55c \uac00\ub824\uc6c0\uc99d \uc9c0\ud45c\ub97c \uc784\uc0c1\uc801 \uc758\uc0ac\uacb0\uc815\uc5d0 \ubc18\uc601\ud560 \ud544\uc694\ub97c \uc81c\uae30\ud55c\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c \ub300\uc0c1\uc740 2013\ub144 1\uc6d4~2022\ub144 7\uc6d4 \uce58\ub8cc\ubc1b\uc740 \uc911\uc99d \uac74\uc120 \ud658\uc790 108\uba85\uc73c\ub85c, \ud2b8\ub818\ud53c\uc5b4 74\uba85\u00b7\uc2a4\ud154\ub77c\ub77c 34\uba85\uc774\uc5c8\ub2e4.<\/li>\n<li>\uc911\uc99d \uae30\uc900\uc740 PASI 10 \ucd08\uacfc \ubc0f BSA 10 \ucd08\uacfc\ub85c \uc815\uc758\ub418\uc5c8\uace0, \ud6a8\ub2a5 \ud3c9\uac00\ub294 28\uc8fc\ucc28\uc5d0 \uc218\ud589\ub410\ub2e4.<\/li>\n<li>\uce58\ub8cc \uc2dc\uc791 \uc2dc\uc810\uc5d0 \uc911\ub4f1\ub3c4~\uc911\uc99d \uac00\ub824\uc6c0(NRS \u22654)\uc744 \ud638\uc18c\ud55c \ud658\uc790\ub294 108\uba85 \uc911 77\uba85(71.3%)\uc774\uc5c8\ub2e4.<\/li>\n<li>77\uba85 \uc911 \uac00\ub824\uc6c0\uc99d\uc774 \uc0ac\uc804 \uc815\uc758\ud55c \uae30\uc900(NRS 4\uc810 \uc774\uc0c1 \uac10\uc18c)\uc73c\ub85c \uac1c\uc120\ub41c \ud658\uc790\ub294 63\uba85(81.8%)\uc774\uc5c8\ub2e4.<\/li>\n<li>\uac00\ub824\uc6c0\uc99d \uac1c\uc120 \ud3ed(NRS \ubcc0\ud654)\uc740 \uc2a4\ud154\ub77c\ub77c\uac00 \ud2b8\ub818\ud53c\uc5b4\ubcf4\ub2e4 \uc720\uc758\ud558\uac8c \ucef8\ub2e4(P=0.033).<\/li>\n<li>PASI \uac10\uc18c\ub294 \ud2b8\ub818\ud53c\uc5b4\uac00 \uc2a4\ud154\ub77c\ub77c\ubcf4\ub2e4 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ud55c \uac1c\uc120\uc744 \ubcf4\uc600\ub2e4(P=0.040).<\/li>\n<li>\uac00\ub824\uc6c0\uc99d\uc774 \uac1c\uc120\ub41c \uad70\uc758 \ud3c9\uade0 NRS\ub294 8.0\uc5d0\uc11c 1.4\ub85c \ud06c\uac8c \uac10\uc18c\ud588\uc73c\ub098, \uac1c\uc120\ub418\uc9c0 \uc54a\uc740 \uad70\uc740 6.1\uc5d0\uc11c 4.6\uc73c\ub85c \uac10\uc18c \ud3ed\uc774 \uc81c\ud55c\uc801\uc774\uc5c8\ub2e4.<\/li>\n<li>\uc804\uccb4 \uc911\ub4f1\ub3c4~\uc911\uc99d \uac00\ub824\uc6c0 \ud658\uc790\uc758 18.2%(14\uba85)\ub294 \ud53c\ubd80 \ubcd1\ubcc0(PASI 75 \uc774\uc0c1 \uac10\uc18c \ud3ec\ud568)\uc774 \ud638\uc804\ub418\uc5c8\uc74c\uc5d0\ub3c4 \uac00\ub824\uc6c0\uc99d \uac10\uc18c\ub294 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ud558\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\uac74\uc120 \uce58\ub8cc\uc5d0\uc11c \ucd5c\uadfc \uc218\ub144\uac04 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc758 \ub3c4\uc785\uc740 \ud53c\ubd80 \ubcd1\ubcc0 \uac1c\uc120\uc5d0 \ud070 \uc9c4\uc804\uc744 \uac00\uc838\uc654\ub2e4. \ub300\ud45c\uc801\uc778 \ud3c9\uac00\uc9c0\ud45c\uc778 PASI(Psoriasis Area and Severity Index)\ub294 \ubcd1\ubcc0\uc758 \ubc94\uc704\uc640 \uc5fc\uc99d \uc815\ub3c4\ub97c \uc218\uce58\ud654\ud574 \uc57d\ubb3c \ud6a8\ub2a5\uc744 \ube44\uad50\ud558\ub294 \ub370 \ud45c\uc900\uc73c\ub85c \uc790\ub9ac\uc7a1\uc558\ub2e4. \uadf8\ub7ec\ub098 \ud658\uc790\ub4e4\uc774 \ud53c\ubd80 \ubcd1\ubcc0\ub9cc\ud07c \uad34\ub85c\uc6cc\ud558\ub294 \uc99d\uc0c1 \uc911 \ud558\ub098\uc778 \uac00\ub824\uc6c0\uc99d(pruritus)\uc740 \uc2dc\uac01\uc801 \uc9c0\ud45c\ub85c \ud3ec\ucc29\ub418\uc9c0 \uc54a\uc544 \uc784\uc0c1\uc801 \uc6b0\uc120\uc21c\uc704\uc5d0\uc11c \uc0c1\ub300\uc801\uc73c\ub85c \uc18c\uc678\ub3fc \uc654\ub2e4. \uac00\ub824\uc6c0\uc99d\uc740 \uc218\uba74\uc7a5\uc560\u00b7\uc815\uc2e0\uac74\uac15 \ubb38\uc81c\u00b7\uc9c1\uc5c5\ud65c\ub3d9 \uc800\ud558 \ub4f1 \uc0b6\uc758 \uc9c8\uc5d0 \uad11\ubc94\uc704\ud55c \uc601\ud5a5\uc744 \ubbf8\uce58\ubbc0\ub85c, \uc774\ub97c \uc5bc\ub9c8\ub098 \uc644\ud654\ud558\ub290\ub0d0\ub294 \uce58\ub8cc \uc120\ud0dd\uc5d0\uc11c \uc911\uc694\ud55c \uc694\uc18c\ub85c \ubd80\uac01\ub418\uace0 \uc788\ub2e4.<\/p>\n<p>\uc81c\uc81c\ubcc4 \uc791\uc6a9\uae30\uc804\ub3c4 \uce58\ub8cc \ud6a8\uacfc\uc758 \uc2a4\ud399\ud2b8\ub7fc\uc744 \uac00\ub974\ub294 \uc694\uc778\uc774\ub2e4. 1\uc138\ub300 \uc57d\ubb3c\ub85c \ubd84\ub958\ub418\ub294 \uc2a4\ud154\ub77c\ub77c\ub294 IL-12\uc640 IL-23\uc744 \ub3d9\uc2dc\uc5d0 \uc5b5\uc81c\ud558\ub294 \ubc18\uba74, \ud2b8\ub818\ud53c\uc5b4\ub294 IL-23\ub9cc\uc744 \uc120\ud0dd\uc801\uc73c\ub85c \ucc28\ub2e8\ud55c\ub2e4. \ub450 \uae30\uc804\uc758 \ucc28\uc774\uac00 \uc5fc\uc99d\uc131 \uacbd\ub85c\ubfd0 \uc544\ub2c8\ub77c \uac00\ub824\uc6c0\uc99d\uacfc \uad00\ub828\ub41c \uc2e0\uacbd\uba74\uc5ed\ud559\uc801 \ubc18\uc751\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc5d0\uc11c \ucc28\uc774\ub97c \ub9cc\ub4e4 \uac00\ub2a5\uc131\uc774 \uc81c\uae30\ub418\uc5b4 \uc654\ub2e4. \ud558\uc9c0\ub9cc \uae30\uc804\uacfc \uc784\uc0c1 \uc99d\uc0c1(\ud2b9\ud788 \uac00\ub824\uc6c0\uc99d) \uac04\uc758 \uc9c1\uc811\uc801 \uc5f0\uacc4\ub294 \uc544\uc9c1 \uba85\ud655\ud788 \uaddc\uba85\ub418\uc9c0 \uc54a\uc544 \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud55c \uc0c1\ud0dc\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\ud300\uc740 2013\ub144 1\uc6d4\ubd80\ud130 2022\ub144 7\uc6d4\uae4c\uc9c0 \uc911\uc99d \uac74\uc120\uc73c\ub85c \uc9c4\ub2e8\ub41c \ud658\uc790 \uac00\uc6b4\ub370 \ud2b8\ub818\ud53c\uc5b4 \ub610\ub294 \uc2a4\ud154\ub77c\ub77c\ub85c \uce58\ub8cc\ubc1b\uc740 \ud658\uc790 108\uba85\uc744 \ud6c4\ud5a5\uc801\uc73c\ub85c \ubd84\uc11d\ud588\ub2e4. \uce58\ub8cc \ud3c9\uac00\ub294 28\uc8fc\ucc28\uc5d0 \uc774\ub904\uc84c\uace0, \uc774\ub294 \uc138 \ucc28\ub840\uc758 \ucd94\uac00 \uc8fc\uc0ac \ud6c4 \uccab \ud6a8\ub2a5\ud3c9\uac00 \uc2dc\uc810\uc5d0 \ud574\ub2f9\ud55c\ub2e4. \ud658\uc790 \uc911 \ub300\ubd80\ubd84\uc774 \uac00\ub824\uc6c0\uc99d\uc744 \ud638\uc18c\ud588\uc73c\uba70, \uc784\uc0c1 \ub370\uc774\ud130\ub294 PASI, BSA, NRS(\uc22b\uc790\ub4f1\uae09\ucc99\ub3c4) \ub4f1 \ud45c\uc900 \uc9c0\ud45c\ub85c \uc815\ub7c9\ud654\ub410\ub2e4.<\/p>\n<p>\ubd84\uc11d \uacb0\uacfc, \uc804\uccb4 \uac00\ub824\uc6c0\uc99d \uac1c\uc120 \ube44\uc728\uc740 \ub192\uc740 \ud3b8\uc73c\ub85c 77\uba85\uc758 \uc911\ub4f1\ub3c4~\uc911\uc99d \uac00\ub824\uc6c0 \ud658\uc790 \uc911 63\uba85(81.8%)\uc774 \uc0ac\uc804 \uc815\uc758\ud55c \uac1c\uc120 \uae30\uc900\uc744 \ucda9\uc871\ud588\ub2e4. \uadf8\ub7ec\ub098 \uad70\ubcc4 \ube44\uad50\uc5d0\uc11c \uac00\ub824\uc6c0\uc99d \uac1c\uc120 \ud3ed\uc740 \uc2a4\ud154\ub77c\ub77c \uadf8\ub8f9\uc5d0\uc11c \ub354 \ucef8\uace0(P=0.033), \ubc18\ub300\ub85c \ud53c\ubd80 \ubcd1\ubcc0 \uac1c\uc120(PASI \uac10\uc18c)\uc740 \ud2b8\ub818\ud53c\uc5b4\uc5d0\uc11c \ub354 \ub69c\ub837\ud55c \uc6b0\uc704\ub97c \ubcf4\uc600\ub2e4(P=0.040). \uc774\ub294 \ub450 \uc57d\uc81c\uac00 \uc11c\ub85c \ub2e4\ub978 \uc784\uc0c1\uc801 \uac15\uc810\uc744 \uac16\uace0 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4.<\/p>\n<p>\ud2b9\uc774\ud55c \uc18c\uadf8\ub8f9 \uacb0\uacfc\ub85c\ub294, \ud53c\ubd80 \ubcd1\ubcc0\uc774 \ub69c\ub837\ud558\uac8c \ud638\uc804\ub41c \ud658\uc790 \uc911 \uc57d 18.2%(14\uba85)\ub294 \uac00\ub824\uc6c0\uc99d \uc9c0\ud45c\uc0c1\uc758 \uc720\uc758\ud55c \uac1c\uc120\uc744 \ubcf4\uc774\uc9c0 \uc54a\uc558\ub2e4. \uc774 \uc9d1\ub2e8\uc740 \uae30\uc800 PASI\uac00 \ubaa8\ub450 10 \uc774\uc0c1\uc774\uc5c8\uace0 \ub2e4\uc218\uc5d0\uc11c PASI 75 \uc774\uc0c1\uc758 \ud53c\ubd80 \uac1c\uc120\uc774 \uad00\ucc30\ub418\uc5c8\uc73c\ub098 VAS\u00b7NRS\u00b7VRS \ub4f1 \uac00\ub824\uc6c0\uc9c0\ud45c\ub294 \uc81c\ud55c\uc801 \ubcc0\ud654\ub97c \ubcf4\uc600\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774 \uac19\uc740 \ubd88\uc77c\uce58\uac00 \ud658\uc790 \ub9de\ucda4 \uce58\ub8cc\uc758 \ud544\uc694\uc131\uc744 \ubd80\uac01\ud55c\ub2e4\uace0 \uc9c0\uc801\ud588\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ub3d9\uc77c \uacc4\uc5f4\uc758 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub77c\ub3c4 \ud45c\uc900 \ud6a8\ub2a5 \uc9c0\ud45c\uc640 \ud658\uc790 \uacbd\ud5d8(\uac00\ub824\uc6c0\uc99d) \uce21\uba74\uc5d0\uc11c \uc11c\ub85c \ub2e4\ub978 \uc7a5\ub2e8\uc810\uc744 \ubcf4\uc77c \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc900\ub2e4. \ud2b8\ub818\ud53c\uc5b4\uc758 PASI \uc6b0\uc704\ub294 \ud53c\ubd80 \ubcd1\ubcc0\uc758 \uc5fc\uc99d\uc801 \uce21\uba74\uc744 \ud6a8\uc728\uc801\uc73c\ub85c \uc5b5\uc81c\ud55c\ub2e4\ub294 \uc810\uc744 \ubc18\uc601\ud558\uba70, \uc2a4\ud154\ub77c\ub77c\uc758 \uac00\ub824\uc6c0 \uac1c\uc120 \uc6b0\uc704\ub294 \uac00\ub824\uc6c0\uc99d \uad00\ub828 \uacbd\ub85c\uc5d0 \ub300\ud55c \uc0c1\ub300\uc801 \ud6a8\uacfc\ub97c \uc2dc\uc0ac\ud55c\ub2e4. \ub2e4\ub9cc \uc778\uacfc\uad00\uacc4 \uaddc\uba85\uc744 \uc704\ud574\uc11c\ub294 \uae30\uc804 \uc5f0\uad6c\uc640 \uc804\ud5a5\uc801 \ube44\uad50 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.<\/p>\n<p>\uc784\uc0c1\uc801 \uad00\uc810\uc5d0\uc11c \ubcf8 \uc5f0\uad6c\uc758 \ud568\uc758\ub294 \ubd84\uba85\ud558\ub2e4. \uc911\uc99d \uac74\uc120 \ud658\uc790\uc5d0\uac8c \uc57d\uc81c\ub97c \uc120\ud0dd\ud560 \ub54c\ub294 \ub2e8\uc21c\ud55c \ubcd1\ubcc0 \uac1c\uc120 \ubaa9\ud45c\ubfd0 \uc544\ub2c8\ub77c \ud658\uc790\uac00 \ud638\uc18c\ud558\ub294 \uc8fc\uad00\uc801 \uc99d\uc0c1\u2014\ud2b9\ud788 \uac00\ub824\uc6c0\uc99d\u2014\uc744 \uce58\ub8cc \uc6b0\uc120\uc21c\uc704\uc5d0 \ud3ec\ud568\uc2dc\ucf1c\uc57c \ud55c\ub2e4. \ud658\uc790\uc5d0 \ub530\ub77c \ubcd1\ubcc0 \uc6b0\uc120\uce58\ub8cc\uac00 \ud544\uc694\ud560 \uc218\ub3c4 \uc788\uace0, \uc0b6\uc758 \uc9c8\uc744 \uac1c\uc120\ud558\uae30 \uc704\ud574 \uac00\ub824\uc6c0 \uc911\uc2ec \uce58\ub8cc \uc804\ub7b5\uc744 \uc120\ud0dd\ud560 \uc218\ub3c4 \uc788\ub2e4. \ube44\uc6a9\u00b7\uc548\uc804\uc131\u00b7\ud22c\uc5ec \ud3b8\uc758\uc131 \ub4f1\ub3c4 \uc885\ud569\uc801\uc73c\ub85c \uace0\ub824\ub3fc\uc57c \ud55c\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc758 \uc77c\ubc18\ud654 \uac00\ub2a5\uc131\uc5d0\ub294 \uc81c\ud55c\uc774 \uc788\ub2e4. \ub2e8\uc77c\uae30\uad00\u00b7\ud6c4\ud5a5 \uc5f0\uad6c \ud2b9\uc131\uc0c1 \uc120\ud0dd \ud3b8\ud5a5\uacfc \uad00\ucc30\uc790 \ud3b8\ud5a5\uc774 \uac1c\uc785\ub420 \uc218 \uc788\uace0, \ucd94\uc801 \uae30\uac04\uc774 28\uc8fc\ub85c \uc7a5\uae30 \ud6a8\uacfc\ub098 \ub0b4\uc131\u00b7\uc7ac\ubc1c \ud328\ud134\uc744 \ud3c9\uac00\ud558\uae30\uc5d0\ub294 \ud55c\uacc4\uac00 \uc788\ub2e4. \ub530\ub77c\uc11c \ub2e4\uae30\uad00 \uc804\ud5a5\uc801 \ubb34\uc791\uc704\ube44\uad50 \uc5f0\uad6c\uc640 \uc7a5\uae30 \ucd94\uc801 \ub370\uc774\ud130\uac00 \ubcf4\uc644\ub418\uc5b4\uc57c \uc784\uc0c1 \uad8c\uace0\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\uc9c0\ud45c<\/th>\n<th>\uc804\uccb4\/\uc138\ubd80<\/th>\n<th>\uc218\uce58<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\ud658\uc790\uc218<\/td>\n<td>\uc804\uccb4<\/td>\n<td>108\uba85 (\ud2b8\ub818\ud53c\uc5b4 74, \uc2a4\ud154\ub77c\ub77c 34)<\/td>\n<\/tr>\n<tr>\n<td>\ucd08\uae30 \uc911\ub4f1\ub3c4\u00b7\uc911\uc99d \uac00\ub824\uc6c0(NRS \u22654)<\/td>\n<td>\ub300\uc0c1<\/td>\n<td>77\uba85(71.3%)<\/td>\n<\/tr>\n<tr>\n<td>\uac00\ub824\uc6c0 \uac1c\uc120(\uc815\uc758: NRS 4\uc810 \uc774\uc0c1 \uac10\uc18c)<\/td>\n<td>\uc131\ucde8<\/td>\n<td>63\uba85(81.8%)<\/td>\n<\/tr>\n<tr>\n<td>NRS \ubcc0\ud654(\uac1c\uc120\uad70 \ud3c9\uade0)<\/td>\n<td>\uac1c\uc120\uad70<\/td>\n<td>8.0 \u2192 1.4<\/td>\n<\/tr>\n<tr>\n<td>NRS \ubcc0\ud654(\ube44\uac1c\uc120\uad70 \ud3c9\uade0)<\/td>\n<td>\ube44\uac1c\uc120\uad70<\/td>\n<td>6.1 \u2192 4.6<\/td>\n<\/tr>\n<tr>\n<td>\uce58\ub8cc\ubcc4 \ud1b5\uacc4<\/td>\n<td>\uac00\ub824\uc6c0(P\uac12)<\/td>\n<td>\uc2a4\ud154\ub77c\ub77c \uc6b0\uc218, P=0.033<\/td>\n<\/tr>\n<tr>\n<td>\uce58\ub8cc\ubcc4 \ud1b5\uacc4<\/td>\n<td>PASI(P\uac12)<\/td>\n<td>\ud2b8\ub818\ud53c\uc5b4 \uc6b0\uc218, P=0.040<\/td>\n<\/tr>\n<\/tbody>\n<\/table><figcaption>\ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5 \ubd84\uc11d \uc8fc\uc694 \uc218\uce58(28\uc8fc \ud3c9\uac00 \uae30\uc900). \ud45c\ub294 \uc6d0\ubb38 \uacb0\uacfc\ub97c \uc694\uc57d\ud55c \uac83\uc784.<\/figcaption><\/figure>\n<p>\uc704 \ud45c\ub294 \uc5f0\uad6c\uc5d0\uc11c \ubcf4\uace0\ud55c \ud575\uc2ec \uc218\uce58\uc640 p\uac12\uc744 \uc694\uc57d\ud55c \uac83\uc774\ub2e4. \ud1b5\uacc4\uc801 \uc720\uc758\uc131\uc740 P\uac12 \uae30\uc900\uc73c\ub85c \uc81c\uc2dc\ub410\uc9c0\ub9cc, \uc784\uc0c1\uc801 \uc758\ubbf8(\uc608: \ud658\uc790 \uac1c\uac1c\uc778\uc758 \uc99d\uc0c1 \uac1c\uc120 \uccb4\uac10)\ub294 \ucd94\uac00\uc801 \ud574\uc11d\uc774 \ud544\uc694\ud558\ub2e4. \ud2b9\ud788 \uac00\ub824\uc6c0\uc99d \uac1c\uc120\uc740 \uc808\ub300 \uc218\uce58 \uac10\uc18c\uc640 \ud658\uc790\uac00 \uccb4\uac10\ud558\ub294 \ud638\uc804 \uc0ac\uc774\uc5d0 \ucc28\uc774\uac00 \uc788\uc744 \uc218 \uc788\uc5b4 \ubcf4\uc870 \ud3c9\uac00(\uc218\uba74, \uc0b6\uc758 \uc9c8 \uc9c0\uc218 \ub4f1)\ub97c \ud3ec\ud568\ud55c \ubcf5\ud569 \ud3c9\uac00\uac00 \ubc14\ub78c\uc9c1\ud558\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c \uacb0\uacfc\ub294 \uce58\ub8cc \uc120\ud0dd \uc2dc \ud658\uc790 \uc99d\uc0c1 \ud504\ub85c\ud30c\uc77c\uc744 \ubc18\uc601\ud574\uc57c \ud55c\ub2e4\ub294 \uc810\uc744 \ub2e4\uc2dc \ud658\uae30\uc2dc\ucf30\ub2e4. \uc5f0\uad6c\ub97c \uc8fc\ub3c4\ud55c \uc7a5\uc6a9\ud604 \uad50\uc218\ub294 \uacb0\uacfc\uc758 \uc784\uc0c1\uc801 \ud568\uc758\ub97c \uac15\uc870\ud558\uba70 \ub9de\ucda4\ud615 \uc811\uadfc\uc758 \ud544\uc694\uc131\uc744 \uc81c\uc548\ud588\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\ud2b8\ub818\ud53c\uc5b4\ub294 \ud53c\ubd80 \ubcd1\ubcc0 \uce58\ub8cc\uc5d0 \ud0c1\uc6d4\ud55c \ud6a8\uacfc\ub97c \ubcf4\uc600\uace0 \uc2a4\ud154\ub77c\ub77c\ub294 \uac00\ub824\uc6c0\uc99d \uc644\ud654\uc5d0 \ub354 \ud6a8\uacfc\uc801\uc774\uc5c8\ub2e4.&#8221;<\/p>\n<p>    <cite>\uc7a5\uc6a9\ud604 \uad50\uc218(\uacbd\ubd81\ub300\ubcd1\uc6d0 \ud53c\ubd80\uacfc)<\/cite>\n  <\/p><\/blockquote>\n<p>\uc774 \ubc1c\uc5b8\uc740 \ub17c\ubb38 \uacb0\uacfc\ub97c \uc694\uc57d\ud55c \uac83\uc73c\ub85c, \ub450 \uc57d\uc81c\uc758 \uc0c1\ub300\uc801 \uac15\uc810\uc744 \uc784\uc0c1\uc801 \uc758\uc0ac\uacb0\uc815\uc5d0 \ubc18\uc601\ud558\uc790\ub294 \ucde8\uc9c0\ub2e4. \ub2e4\ub9cc \uad50\uc218\ub294 \ucd94\uac00 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uac00\ub824\uc6c0\uc99d\uc758 \uae30\uc804 \uaddc\uba85\uacfc \ud658\uc790 \ud2b9\uc131\ubcc4 \uc57d\ubb3c \ubc18\uc751\uc744 \ubc1d\ud600\uc57c \ud55c\ub2e4\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n<p>\uc5f0\uad6c\ud300\uc758 \ub17c\ubb38 \uc790\uccb4\ub3c4 \uacb0\uacfc \ud574\uc11d\uc5d0 \uc2e0\uc911\uc744 \uae30\ud560 \uac83\uc744 \uad8c\uace0\ud588\ub2e4. \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5 \ubd84\uc11d\uc758 \ud55c\uacc4\ub97c \uc778\uc815\ud558\uba74\uc11c\ub3c4 \uc784\uc0c1 \ud604\uc7a5\uc5d0\uc11c \ud754\ud788 \uac04\uacfc\ub418\ub294 \uac00\ub824\uc6c0\uc99d \uc9c0\ud45c\ub97c \uccb4\uacc4\uc801\uc73c\ub85c \ud3c9\uac00\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ubbf8\uac00 \uc788\ub2e4\ub294 \ud3c9\uac00\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\uac74\uc120\uc131 \uac00\ub824\uc6c0\uc99d\uc758 \ub9de\ucda4\ud615 \uce58\ub8cc\ub97c \uc704\ud55c \ucd94\uac00\uc801\uc778 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.&#8221;<\/p>\n<p>    <cite>\uc5f0\uad6c\ud300(Annals of Dermatology \uac8c\uc7ac \ub17c\ubb38)<\/cite>\n  <\/p><\/blockquote>\n<p>\uc5f0\uad6c\ud300\uc740 \ub17c\ubb38\uc5d0\uc11c \uc81c\ud55c\uc810\uc744 \uba85\uc2dc\ud558\uace0 \ub2e4\uae30\uad00\u00b7\uc804\ud5a5\uc801 \uc5f0\uad6c\uc758 \ud544\uc694\uc131\uc744 \uc81c\uae30\ud588\ub2e4. \uc784\uc0c1\ud604\uc7a5\uc5d0\uc11c\ub294 \uc774 \uac19\uc740 \uc99d\uac70\ub97c \ubc14\ud0d5\uc73c\ub85c \ud658\uc790\uc640\uc758 \ucda9\ubd84\ud55c \uc0c1\ub2f4\uc744 \ud1b5\ud574 \uc57d\uc81c\ub97c \uc120\ud0dd\ud574\uc57c \ud55c\ub2e4\ub294 \ud574\uc11d\uc774 \ub530\ub978\ub2e4.<\/p>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>IL-12\/23 \uc5b5\uc81c\uc81c\ub294 IL-12\uc640 IL-23 \ub450 \uc0ac\uc774\ud1a0\uce74\uc778\uc744 \ub3d9\uc2dc\uc5d0 \ucc28\ub2e8\ud574 \uad11\ubc94\uc704\ud55c \uc5fc\uc99d \uacbd\ub85c\ub97c \uc5b5\uc81c\ud55c\ub2e4. IL-23 \ub2e8\uc77c \uc5b5\uc81c\uc81c\ub294 \ubcf4\ub2e4 \ud45c\uc801\ud654\ub41c \uae30\uc804\uc73c\ub85c \uc5fc\uc99d\ubc18\uc751\uc758 \ud575\uc2ec \ucd95 \uc911 \ud558\ub098\uc778 Th17 \uacbd\ub85c\ub97c \uc9c1\uc811 \uc5b5\uc81c\ud55c\ub2e4. PASI\ub294 \ubcd1\ubcc0\uc758 \uba74\uc801\uacfc \ud64d\ubc18\u00b7\ub450\uaed8\u00b7\ube44\ub298 \ub4f1\uc744 \uc885\ud569\ud574 \uc810\uc218\ud654\ud558\ub294 \uc9c0\ud45c\ub85c, \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \uc8fc\uc694 \ud6a8\ub2a5 \uc9c0\ud45c\ub85c \uc0ac\uc6a9\ub41c\ub2e4. NRS(\uc22b\uc790 \ub4f1\uae09 \ucc99\ub3c4)\ub294 \ud658\uc790\uac00 \uc8fc\uad00\uc801\uc73c\ub85c \ubcf4\uace0\ud558\ub294 \uac00\ub824\uc6c0\uc758 \uac15\ub3c4\ub97c 0~10 \uc0ac\uc774\ub85c \ud45c\uae30\ud574 \uce58\ub8cc \uc804\ud6c4 \ubcc0\ud654\ub97c \ube44\uad50\ud558\ub294 \uac04\ub2e8\ud55c \ub3c4\uad6c\ub2e4. \ud6c4\ud5a5 \uc5f0\uad6c\ub294 \uc2e4\uc81c \uc9c4\ub8cc \ub370\uc774\ud130\ub97c \ud65c\uc6a9\ud574 \ud604\uc2e4\uc801 \uc99d\uac70\ub97c \uc81c\uacf5\ud558\uc9c0\ub9cc \ubb34\uc791\uc704\ubc30\uc815\uc774 \uc5c6\uc5b4 \uad50\ub780\uc694\uc778\uc744 \uc644\uc804\ud788 \ubc30\uc81c\ud558\uae30 \uc5b4\ub835\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\uac00\ub824\uc6c0\uc99d \ucc28\uc774\uac00 \uc57d\ubb3c\uc758 \uc815\ud655\ud55c \uba74\uc5ed\ud559\uc801 \uae30\uc804\uc5d0 \uc758\ud574 \ubc1c\uc0dd\ud558\ub294\uc9c0 \uc5ec\ubd80\ub294 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\ub2e8\uc77c\uae30\uad00\u00b7\ud6c4\ud5a5 \uc124\uacc4\ub85c \uc778\ud55c \uc120\ud0dd \ud3b8\ud5a5\uacfc \uc7a0\uc7ac\uc801 \uad50\ub780\uc694\uc778\uc758 \uc601\ud5a5\uc774 \uc644\uc804\ud788 \ubc30\uc81c\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc7a5\uae30 \uc720\uc9c0\uc694\ubc95\uc5d0 \ub530\ub978 \uc9c0\uc18d\uc801 \ud6a8\uacfc\uc640 \uc548\uc804\uc131, \uc7ac\ubc1c\ub960 \ube44\uad50\ub294 \ubcf8 \uc5f0\uad6c\uc5d0\uc11c \ub2e4\ub8e8\uc5b4\uc9c0\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5 \ubd84\uc11d\uc740 \ud2b8\ub818\ud53c\uc5b4(\uad6c\uc140\ucfe0\ub9d9)\uc640 \uc2a4\ud154\ub77c\ub77c(\uc6b0\uc2a4\ud14c\ud0a4\ub204\ub9d9)\uac00 \uc911\uc99d \uac74\uc120 \uce58\ub8cc\uc5d0\uc11c \uc11c\ub85c \ub2e4\ub978 \uc784\uc0c1\uc801 \uac15\uc810\uc744 \ubcf4\uc778\ub2e4\ub294 \uc810\uc744 \uc81c\uc2dc\ud588\ub2e4. \ud2b8\ub818\ud53c\uc5b4\ub294 \ud45c\uc900\uc801 \ubcd1\ubcc0 \uc9c0\ud45c(PASI) \uac1c\uc120\uc5d0\uc11c \uc6b0\uc704\ub97c \ubcf4\uc600\uace0, \uc2a4\ud154\ub77c\ub77c\ub294 \ud658\uc790\uac00 \uc9c1\uc811 \ud638\uc18c\ud558\ub294 \uac00\ub824\uc6c0\uc99d \uc644\ud654\uc5d0\uc11c \ub354 \ud070 \ud3ed\uc758 \uac1c\uc120\uc744 \ubcf4\uc600\ub2e4. \uc774\ub294 \uce58\ub8cc \uc120\ud0dd \uc2dc \ud658\uc790 \uac1c\ubcc4 \uc99d\uc0c1\uacfc \uc0b6\uc758 \uc9c8 \uc694\uc18c\ub97c \ubc18\uc601\ud55c \ub9de\ucda4\ud615 \uc811\uadfc\uc758 \ud544\uc694\uc131\uc744 \ub4b7\ubc1b\uce68\ud55c\ub2e4.<\/p>\n<p>\ud5a5\ud6c4 \uad8c\uace0\ub294 \ub2e4\uae30\uad00 \uc804\ud5a5\uc801 \ube44\uad50 \uc5f0\uad6c\uc640 \uc7a5\uae30 \ucd94\uc801 \ub370\uc774\ud130\ub97c \ud1b5\ud574 \ubcf4\uc644\ub418\uc5b4\uc57c \ud55c\ub2e4. \uc784\uc0c1\uac00\ub294 \ud604\uc7ac \uc218\uc900\uc758 \uadfc\uac70\ub97c \ubc14\ud0d5\uc73c\ub85c \ud658\uc790\uc640 \uc99d\uc0c1 \uc6b0\uc120\uc21c\uc704\uc5d0 \ub300\ud574 \ucda9\ubd84\ud788 \uc0c1\ub2f4\ud558\uace0, \uce58\ub8cc \ubaa9\ud45c\ub97c \uba85\ud655\ud788 \uc124\uc815\ud55c \ub4a4 \uc57d\uc81c\ub97c \uc120\ud0dd\ud558\ub294 \uac83\uc774 \ubc14\ub78c\uc9c1\ud558\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.monews.co.kr\/news\/articleView.html?idxno=409086\" target=\"_blank\" rel=\"noopener\">\uba54\ub514\uce7c\uc5c5\uc800\ubc84 \ubcf4\ub3c4(\uc5b8\ub860)<\/a><\/li>\n<li><a href=\"https:\/\/doi.org\/10.5021\/ad.25.012\" target=\"_blank\" rel=\"noopener\">Annals of Dermatology(\ud559\uc220\uc9c0, \ub17c\ubb38 DOI)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \uacbd\ubd81\ub300\ubcd1\uc6d0 \uc7a5\uc6a9\ud604 \uad50\uc218\ud300\uc774 \ub300\ud55c\ud53c\ubd80\uacfc\ud559\ud68c\uc9c0 Annals of Dermatology\uc5d0 \ubc1c\ud45c\ud55c \uad6d\ub0b4 \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5 \ubd84\uc11d(2013-01~2022-07, \ud658\uc790 108\uba85)\uc740 \ud2b8\ub818\ud53c\uc5b4(\uad6c\uc140\ucfe0\ub9d9, 74\uba85)\uc640 \uc2a4\ud154\ub77c\ub77c(\uc6b0\uc2a4\ud14c\ud0a4\ub204\ub9d9, 34\uba85)\uc758 \uc911\uc99d \uac74\uc120 \uce58\ub8cc \uacb0\uacfc\ub97c \ube44\uad50\ud588\ub2e4. 28\uc8fc \ud3c9\uac00 \uc2dc \ud2b8\ub818\ud53c\uc5b4\ub294 \ud53c\ubd80 \ubcd1\ubcc0 \uac1c\uc120(PASI \uac10\uc18c)\uc5d0\uc11c \ud1b5\uacc4\uc801\uc73c\ub85c \ub354 \uc6b0\uc218\ud588\uace0(P=0.040), \uc2a4\ud154\ub77c\ub77c\ub294 \uac00\ub824\uc6c0\uc99d(NRS \ubcc0\ud654) \uc644\ud654 \ud3ed\uc774 \ub354 \ucef8\ub2e4(P=0.033). \uc5f0\uad6c\ub294 \ud658\uc790 \uc0b6\uc758 \uc9c8\uacfc \ubc00\uc811\ud55c \uac00\ub824\uc6c0\uc99d \uc9c0\ud45c\ub97c \uc784\uc0c1\uc801 \uc758\uc0ac\uacb0\uc815\uc5d0 \ubc18\uc601\ud560 \ud544\uc694\ub97c \uc81c\uae30\ud55c\ub2e4. &#8230; <a title=\"\ud2b8\ub818\ud53c\uc5b4 vs \uc2a4\ud154\ub77c\ub77c, \uc911\uc99d \uac74\uc120\uc11c &#8216;\uc11c\ub85c \ub2e4\ub978&#8217; \uac15\uc810 &#8211; \uba54\ub514\uce7c\uc5c5\uc800\ubc84\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/tremfya-stelara-psoriasis\/\" aria-label=\"\ud2b8\ub818\ud53c\uc5b4 vs \uc2a4\ud154\ub77c\ub77c, \uc911\uc99d \uac74\uc120\uc11c &#8216;\uc11c\ub85c \ub2e4\ub978&#8217; \uac15\uc810 &#8211; \uba54\ub514\uce7c\uc5c5\uc800\ubc84\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":7411,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\ud2b8\ub818\ud53c\uc5b4 vs \uc2a4\ud154\ub77c\ub77c, \uc911\uc99d \uac74\uc120\uc11c \ub2e4\ub978 \uac15\uc810 | \uba54\ub514\uce7c\uc5c5\uc800\ubc84","rank_math_description":"\uad6d\ub0b4 \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5 \ubd84\uc11d(108\uba85, 28\uc8fc)\uc5d0\uc11c \ud2b8\ub818\ud53c\uc5b4\ub294 PASI \uac1c\uc120 \uc6b0\uc704, \uc2a4\ud154\ub77c\ub77c\ub294 \uac00\ub824\uc6c0\uc99d \uc644\ud654 \uc6b0\uc704\ub97c \ubcf4\uc600\ub2e4(PASI P=0.040, NRS P=0.033). \ub9de\ucda4\ud615 \uce58\ub8cc\uc758 \ud544\uc694\uc131\uc744 \ubd84\uc11d\ud569\ub2c8\ub2e4.","rank_math_focus_keyword":"\uac74\uc120, \ud2b8\ub818\ud53c\uc5b4, \uc2a4\ud154\ub77c\ub77c, \uac00\ub824\uc6c0\uc99d, PASI","footnotes":""},"categories":[2],"tags":[],"class_list":["post-7419","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/7419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=7419"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/7419\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/7411"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=7419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=7419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=7419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}