{"id":8101,"date":"2026-02-06T19:08:57","date_gmt":"2026-02-06T10:08:57","guid":{"rendered":"https:\/\/readtrends.com\/ko\/edinburgh-ctnnb1-342-variants-map\/"},"modified":"2026-02-06T19:08:57","modified_gmt":"2026-02-06T10:08:57","slug":"edinburgh-ctnnb1-342-variants-map","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/edinburgh-ctnnb1-342-variants-map\/","title":{"rendered":"\uc5d0\ub4e0\ubc84\ub7ec\ub300, \uc8fc\uc694 \uc554 \uc720\uc804\uc790 342\uac00\uc9c0 \ub3cc\uc5f0\ubcc0\uc774 \ud6a8\uacfc \uc644\uc804 \ub9e4\ud551 \uc131\uacf5"},"content":{"rendered":"<article>\n<p><time>2026\ub144 2\uc6d4 6\uc77c<\/time> \u2014 \uc601\uad6d \uc5d0\ub4e0\ubc84\ub7ec \ub300\ud559\uad50 \uc5f0\uad6c\ud300\uc774 \uc554\uc5d0\uc11c \ube48\ubc1c\ud558\ub294 \uc720\uc804\uc790 CTNNB1\uc758 \ud575\uc2ec \ubd80\uc704\uc5d0\uc11c \uac00\ub2a5\ud55c 342\uac00\uc9c0 \ub2e8\uc77c \uc5fc\uae30 \ub3cc\uc5f0\ubcc0\uc774\ub97c \ubaa8\ub450 \uc2e4\ud5d8\uc801\uc73c\ub85c \uac80\uc0ac\ud574, \uac01 \ubcc0\uc774\uac00 \u03b2-\uce74\ud14c\ub2cc \uc2e0\ud638\ub97c \uc5bc\ub9c8\ub098 \uac15\ud558\uac8c \ud65c\uc131\ud654\ud558\ub294\uc9c0 \uce21\uc815\ud55c \uc804\uc218 \uc9c0\ub3c4\ub97c \ubc1c\ud45c\ud588\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \ub9c8\uc6b0\uc2a4 \uc904\uae30\uc138\ud3ec \ubaa8\ub378\uacfc \ucca8\ub2e8 \uc720\uc804\uccb4 \ud3b8\uc9d1\u00b7\ud615\uad11 \ubd84\uc11d\uc744 \ud65c\uc6a9\ud574 \ub3cc\uc5f0\ubcc0\uc774\ubcc4 \ud65c\uc131\ub3c4 \uc810\uc218\ub97c \uc0b0\ucd9c\ud558\uace0, \uc218\ucc9c \uba85\uc758 \uc554 \ud658\uc790 \uc720\uc804\uc790 \ub370\uc774\ud130\uc640 \ube44\uad50\ud574 \uc9c0\ub3c4\uc758 \uc608\uce21\ub825\uc774 \ud658\uc790\uad70\uc5d0\uc11c \uc7ac\ud604\ub428\uc744 \ud655\uc778\ud588\ub2e4. \uc774\ubc88 \uacb0\uacfc\ub294 \ud2b9\uc815 \ub3cc\uc5f0\ubcc0\uc774\uc758 \uac15\ub3c4\uac00 \uc885\uc591\uc758 \uba74\uc5ed \ud658\uacbd\uacfc \uc870\uc9c1\ubcc4 \ubc1c\uc0dd \uc591\uc0c1\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4\ub294 \uadfc\uac70\ub97c \uc81c\uacf5\ud558\uba70, \ub9de\ucda4\ud615 \uce58\ub8cc \uc804\ub7b5 \uc218\ub9bd\uc5d0 \ud65c\uc6a9\ub420 \uc218 \uc788\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c\ud300\uc740 CTNNB1 \uc720\uc804\uc790 \ud575\uc2ec \uc601\uc5ed\uc5d0\uc11c \uac00\ub2a5\ud55c \ubaa8\ub4e0 342\uac1c \ub2e8\uc77c \uc5fc\uae30 \ubcc0\uc774\ub97c \uc2e4\ud5d8\uc801\uc73c\ub85c \uc0dd\uc131\u00b7\ud3c9\uac00\ud588\ub2e4. \uac01 \ubcc0\uc774\uc5d0 \ub300\ud574 \u03b2-\uce74\ud14c\ub2cc \uacbd\ub85c \ud65c\uc131\ud654 \uac15\ub3c4\ub97c \uc815\ub7c9\ud654\ud588\ub2e4.<\/li>\n<li>\uc2e4\ud5d8\uc5d0\ub294 \uc778\uac04 \u03b2-\uce74\ud14c\ub2cc \uc2e0\ud638\ub97c \uc798 \ubc18\uc601\ud558\ub294 \ub9c8\uc6b0\uc2a4 \uc904\uae30\uc138\ud3ec \ubaa8\ub378\uacfc \uc720\uc804\uccb4 \ud3b8\uc9d1, \ud615\uad11 \uae30\ubc18 \ubd84\ub958(\ud50c\ub85c\uc6b0 \uc0ac\uc774\ud1a0\uba54\ud2b8\ub9ac \ub4f1)\uac00 \uc0ac\uc6a9\ub410\ub2e4.<\/li>\n<li>\uacfc\uac70 \uad00\ucc30\ub41c CTNNB1 \ubcc0\uc774 70\uac1c \uc774\uc0c1\uc740 \uc11c\ub85c \ub2e4\ub978 \ud65c\uc131\ub3c4\ub97c \ubcf4\uc600\uc73c\uba70, \uc77c\ubd80\ub294 \uc57d\ud55c \ud65c\uc131 \uc99d\uac00\uc5d0 \uadf8\uce5c \ubc18\uba74 \ub2e4\ub978 \ubcc0\uc774\ub294 \ub9e4\uc6b0 \uac15\ud55c \uc2e0\ud638\ub97c \uc720\ubc1c\ud588\ub2e4.<\/li>\n<li>\uc5f0\uad6c \uacb0\uacfc\ub294 \uc218\ucc9c \uba85\uc758 \uc554 \ud658\uc790 \uc720\uc804\uccb4 \ub370\uc774\ud130(\uc554\uc885 \ud1b5\ud569 \ub370\uc774\ud130\ubca0\uc774\uc2a4 \ube44\uad50)\ub97c \ud1b5\ud574 \uac80\uc99d\ub3fc, \uc2e4\ud5d8 \uc810\uc218\uc640 \ud658\uc790\uad70\uc5d0\uc11c\uc758 \ub3cc\uc5f0\ubcc0\uc774 \ubc1c\uc0dd \uc591\uc0c1\uc774 \ub192\uc740 \uc0c1\uad00\uc131\uc744 \ubcf4\uc600\ub2e4.<\/li>\n<li>\uac04\uc554 \uc0d8\ud50c\uc5d0\uc11c\ub294 \uc57d\ud55c \ud65c\uc131\uc758 CTNNB1 \ubcc0\uc774\ub97c \uac00\uc9c4 \uc885\uc591\uc5d0\uc11c \uba74\uc5ed\uc138\ud3ec \uce68\uc724\uc774 \ub354 \ub192\uc558\uace0, \uac15\ud55c \ud65c\uc131\uc758 \ubcc0\uc774\ub97c \uac00\uc9c4 \uc885\uc591\uc5d0\uc11c\ub294 \uba74\uc5ed\uc138\ud3ec\uac00 \uc801\uac8c \uad00\ucc30\ub418\ub294 \ub450 \uadf8\ub8f9\uc774 \ud655\uc778\ub410\ub2e4.<\/li>\n<li>\ud574\ub2f9 \ub17c\ubb38\uc740 \ud559\uc220\uc9c0 Nature Genetics\uc5d0 \uac8c\uc7ac\ub410\uace0, \uc5f0\uad6c\ube44\ub294 \uc758\ud559\uc5f0\uad6c\uc704\uc6d0\ud68c(MRC)\uc640 \uc0dd\uba85\uacf5\ud559\u00b7\uc0dd\ubb3c\uacfc\ud559\uc5f0\uad6c\uc704\uc6d0\ud68c(BBSRC)\uac00 \uc9c0\uc6d0\ud588\ub2e4.<\/li>\n<li>\uc5f0\uad6c\ub294 \uc5d0\ub4e0\ubc84\ub7ec \ub300\ud559\uad50 \uc8fc\ub3c4\ud558\uc5d0 \ub77c\uc774\ub374 \ub300\ud559 \uc758\ub8cc\uc13c\ud130\uc640 \ucf54\uce58 \ub300\ud559\uad50 \uc5f0\uad6c\ud300\uc774 \uacf5\ub3d9 \uc218\ud589\ud588\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>CTNNB1 \uc720\uc804\uc790\ub294 \u03b2-\uce74\ud14c\ub2cc \ub2e8\ubc31\uc9c8\uc744 \uc554\ud638\ud654\ud558\uba70, \u03b2-\uce74\ud14c\ub2cc\uc740 \uc815\uc0c1 \uc870\uc9c1\uc5d0\uc11c \uc138\ud3ec \uc131\uc7a5\uacfc \uc7ac\uc0dd\uc744 \uc870\uc808\ud558\ub294 \ud575\uc2ec \uc2e0\ud638\uc804\ub2ec\uc790\ub2e4. \uc815\uc0c1 \uc0c1\ud0dc\uc5d0\uc11c\ub294 \ud2b9\uc815 \uc601\uc5ed\uc5d0 \ud45c\uc801\ub41c \ubd84\ud574 \uc2e0\ud638\uac00 \u03b2-\uce74\ud14c\ub2cc\uc758 \uc801\uc808\ud55c \uc81c\uac70\ub97c \uc720\ub3c4\ud558\uc9c0\ub9cc, \uc774 \ubd80\uc704\uc5d0 \ub3cc\uc5f0\ubcc0\uc774\uac00 \uc0dd\uae30\uba74 \ubd84\ud574 \uc2e0\ud638\uac00 \uc190\uc0c1\ub418\uc5b4 \ub2e8\ubc31\uc9c8\uc774 \ucd95\uc801\ub41c\ub2e4. \ucd95\uc801\ub41c \u03b2-\uce74\ud14c\ub2cc\uc740 \ud575\uc73c\ub85c \uc774\ub3d9\ud574 \uc99d\uc2dd \uad00\ub828 \uc720\uc804\uc790\ub4e4\uc744 \ud65c\uc131\ud654\ud568\uc73c\ub85c\uc368 \uc885\uc591 \ubc1c\uc0dd\uacfc \uc131\uc7a5\uc744 \ucd09\uc9c4\ud55c\ub2e4.<\/p>\n<p>\uc784\uc0c1\uc801\uc73c\ub85c CTNNB1\uc758 &#8216;\ud56b\uc2a4\ud31f&#8217; \ub3cc\uc5f0\ubcc0\uc774\ub294 \uac04\uc554, \ud53c\ubd80\uc554, \ubd80\uc2e0\uc885\uc591 \ub4f1 \ub2e4\uc591\ud55c \uc554\uc885\uc5d0\uc11c \ube48\ubc1c\ud574 \uc654\uc73c\ub098, \ub3d9\uc77c \uc704\uce58\uc758 \uc11c\ub85c \ub2e4\ub978 \ub3cc\uc5f0\ubcc0\uc774\ub4e4\uc774 \uae30\ub2a5\uc801\uc73c\ub85c \ub3d9\uc77c\ud55c\uc9c0 \uc5ec\ubd80\ub294 \ubd88\uba85\ud655\ud588\ub2e4. \uacfc\uac70 \uc5f0\uad6c\ub4e4\uc740 \uac1c\ubcc4 \ubcc0\uc774\uc5d0 \ub300\ud55c \ub2e8\ud3b8\uc801 \ud3c9\uac00\uc5d0 \uba38\ubb3c\ub800\uace0, \ub300\uaddc\ubaa8 \uc804\uc218 \uac80\uc0ac\ub294 \ubd80\uc871\ud588\ub2e4. \uc774\ub7f0 \ubc30\uacbd\uc5d0\uc11c \ubcc0\uc774\ubcc4 \uae30\ub2a5 \ucc28\uc774\ub97c \uccb4\uacc4\uc801\uc73c\ub85c \uaddc\uba85\ud558\ub824\ub294 \uc694\uad6c\uac00 \ucee4\uc84c\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5d0\ub4e0\ubc84\ub7ec\ub300 \uc720\uc804\ud559 \ubc0f \uc554 \uc5f0\uad6c\uc18c\uc758 \uc564\ub4dc\ub958 \uc6b0\ub4dc \uc5f0\uad6c\ud300\uc740 CTNNB1\uc758 \ubd84\ud574 \uc2e0\ud638 \ubd80\uc704(\ud56b\uc2a4\ud31f)\ub97c \ud45c\uc801\ud574 \uac00\ub2a5\ud55c \ubaa8\ub4e0 \ub2e8\uc77c \uc5fc\uae30 \uce58\ud658\uc744 \uc124\uacc4\u00b7\uc0dd\uc131\ud588\ub2e4. \uac01 \ubcc0\uc774\uc758 \u03b2-\uce74\ud14c\ub2cc \uacbd\ub85c \ud65c\uc131\ud654 \uc815\ub3c4\ub294 \ud615\uad11 \ub9ac\ud3ec\ud130\ub97c \uc774\uc6a9\ud55c \uc815\ub7c9\uc801 \ud310\ub3c5\uc73c\ub85c \uce21\uc815\ub410\uace0, \uc774\ub97c \ud1b5\ud574 \ubcc0\uc774\ubcc4 &#8216;\ud65c\uc131\ub3c4 \uc810\uc218&#8217;\uac00 \uc0b0\ucd9c\ub410\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774 \uc2e4\ud5d8\uc801 \uc810\uc218\uc640 \uc784\uc0c1 \ud658\uc790 \ub370\uc774\ud130\uc758 \ub3cc\uc5f0\ubcc0\uc774 \ubd84\ud3ec\ub97c \ube44\uad50\ud574 \uc9c0\ub3c4\uc758 \uc608\uce21\ub825\uc744 \uac80\uc99d\ud588\ub2e4.<\/p>\n<p>\uc2e4\ud5d8 \uacb0\uacfc\ub294 \ub3cc\uc5f0\ubcc0\uc774\ub4e4 \uc0ac\uc774\uc5d0 \ud070 \ud65c\uc131\ub3c4 \ucc28\uc774\uac00 \uc788\uc74c\uc744 \ubd84\uba85\ud788 \ud588\ub2e4. \uc77c\ubd80 \ubcc0\uc774\ub294 \uacbd\ubbf8\ud55c \uacbd\ub85c \ud65c\uc131\ud654\ub9cc\uc744 \uc720\ubc1c\ud588\uc73c\ub098, \ub2e4\ub978 \ubcc0\uc774\ub294 \uac15\ub825\ud55c \uc2e0\ud638\ub97c \uc77c\uc73c\ucf1c \uc885\uc591 \uc131\uc7a5 \uad00\ub828 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \ud06c\uac8c \uc99d\uac00\uc2dc\ucf30\ub2e4. \uc870\uc9c1\ubcc4\ub85c\ub294 \ud2b9\uc815 \uc218\uc900\uc758 \u03b2-\uce74\ud14c\ub2cc \ud65c\uc131\ud654\ub97c \uc0dd\uc131\ud558\ub294 \ubcc0\uc774\uac00 \uc120\ud638\ub418\ub294 \uacbd\ud5a5\uc774 \uad00\ucc30\ub418\uc5b4, \uac19\uc740 \uc720\uc804\uc790 \ub0b4\uc5d0\uc11c\ub3c4 \uc554\uc885\uc5d0 \ub530\ub978 \uc120\ud0dd \uc555\ub825 \ucc28\uc774\uac00 \uc788\ub2e4\ub294 \uc810\uc744 \uc2dc\uc0ac\ud588\ub2e4.<\/p>\n<p>\uac04\uc554 \uc0ac\ub840 \ubd84\uc11d\uc5d0\uc11c\ub294 \uc57d\ud55c \ud65c\uc131 \ubcc0\uc774\uad70\uacfc \uac15\ud55c \ud65c\uc131 \ubcc0\uc774\uad70 \uac04\uc5d0 \uba74\uc5ed \ubbf8\uc138\ud658\uacbd \ucc28\uc774\uac00 \ud655\uc778\ub410\ub2e4. \uc57d\ud55c \ud65c\uc131 \ubcc0\uc774\uad70\uc740 \uba74\uc5ed\uc138\ud3ec(\uc608: T\uc138\ud3ec)\uc758 \uce68\uc724\uc774 \uc0c1\ub300\uc801\uc73c\ub85c \ub192\uc558\uace0, \uac15\ud55c \ud65c\uc131 \ubcc0\uc774\uad70\uc740 \uba74\uc5ed\uc138\ud3ec\uac00 \uc801\uc5b4 \uba74\uc5ed \ud68c\ud53c \uc131\ud5a5\uc744 \ubcf4\uc600\ub2e4. \uc774\ub7ec\ud55c \uc0c1\uad00\uc131\uc740 \ub3cc\uc5f0\ubcc0\uc774\uc758 \uae30\ub2a5\uc801 \ub4f1\uae09\uc774 \uba74\uc5ed\uce58\ub8cc \ubc18\uc751\uc131\uacfc \uc5f0\uacb0\ub420 \uac00\ub2a5\uc131\uc744 \uc81c\uae30\ud55c\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uccab\uc9f8, \uc774\ubc88 \uc804\uc218 \uc9c0\ub3c4\ub294 \ub2e8\uc77c \uc5fc\uae30 \uc218\uc900\uc758 \uc138\ubc00\ud55c \uae30\ub2a5 \ucc28\uc774\ub97c \uaddc\uba85\ud568\uc73c\ub85c\uc368 &#8216;\ub3d9\uc77c \uc720\uc804\uc790, \ub3d9\uc77c \uc704\uce58&#8217;\ub77c\ub294 \uad00\uce21\uc774 \ud56d\uc0c1 \ub3d9\uc77c\ud55c \uae30\ub2a5\uc801 \uacb0\uacfc\ub97c \ub73b\ud558\uc9c0 \uc54a\uc74c\uc744 \uc2e4\ud5d8\uc801\uc73c\ub85c \uc785\uc99d\ud588\ub2e4. \uc784\uc0c1 \ubcc0\uc774 \ud574\uc11d\uc5d0\uc11c \ub2e8\uc21c \uc704\uce58 \uae30\ubc18 \ubd84\ub958\ub97c \ub118\uc5b4 \ubcc0\uc774\ubcc4 \uae30\ub2a5 \uc815\ubcf4\ub97c \ud1b5\ud569\ud560 \ud544\uc694\uac00 \ucee4\uc84c\ub2e4.<\/p>\n<p>\ub458\uc9f8, \uc870\uc9c1\ubcc4 \ubcc0\uc774 \uc120\ud638\uc131\uc740 \uc885\uc591 \ubc1c\uc0dd \ud658\uacbd\uacfc \uc120\ud0dd \uc555\ub825\uc758 \ub2e4\uc591\uc131\uc744 \ubc18\uc601\ud55c\ub2e4. \uc608\ucee8\ub300 \uac04\uc870\uc9c1\uc5d0\uc11c\ub294 \uc911\uac04 \uc218\uc900\uc758 \u03b2-\uce74\ud14c\ub2cc \ud65c\uc131\ub9cc\uc73c\ub85c\ub3c4 \uc885\uc591 \uc131\uc7a5\uc5d0 \uc720\ub9ac\ud560 \uc218 \uc788\uace0, \ud53c\ubd80\ub098 \uc2e0\uacbd\uacc4\uc5d0\uc11c\ub294 \ub2e4\ub978 \uc218\uc900\uc758 \ud65c\uc131\ub3c4\uac00 \uc720\ub9ac\ud560 \uc218 \uc788\ub2e4. \uc774\ub294 \ud5a5\ud6c4 \ud45c\uc801\uce58\ub8cc\ub098 \uc608\ud6c4 \uc608\uce21 \ubaa8\ub378\uc744 \uc870\uc9c1 \ud2b9\uc774\uc801\uc73c\ub85c \uc124\uacc4\ud574\uc57c \ud568\uc744 \ub73b\ud55c\ub2e4.<\/p>\n<p>\uc14b\uc9f8, \uba74\uc5ed\ud658\uacbd\uacfc\uc758 \uc5f0\uad00\uc131\uc740 \uc2e4\uc6a9\uc801 \ud568\uc758\ub97c \uac16\ub294\ub2e4. \ub9cc\uc57d \uac15\ud55c \ud65c\uc131 \ubcc0\uc774\ub97c \uac00\uc9c4 \uc885\uc591\uc774 \uba74\uc5ed\uc138\ud3ec \uce68\uc724\uc774 \ub0ae\uc544 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \ubc18\uc751\uc774 \ub5a8\uc5b4\uc9c4\ub2e4\uba74, \ub3cc\uc5f0\ubcc0\uc774 \uae30\ub2a5 \ub4f1\uae09\uc740 \uce58\ub8cc \uc120\ud0dd \uae30\uc900\uc5d0 \ud3ec\ud568\ub420 \uc218 \uc788\ub2e4. \uc784\uc0c1\uc2dc\ud5d8 \uc124\uacc4\ub098 \ud658\uc790 \uacc4\uce35\ud654(stratification)\uc5d0\uc11c \ubcc0\uc774\ubcc4 \uae30\ub2a5 \uc810\uc218\uac00 \ubcf4\uc870 \uc9c0\ud45c\ub85c \ud65c\uc6a9\ub420 \uc5ec\uc9c0\uac00 \uc788\ub2e4.<\/p>\n<p>\ub9c8\uc9c0\ub9c9\uc73c\ub85c, \uc5f0\uad6c\uc758 \ubc94\uc6a9\uc131 \ubc0f \ud55c\uacc4\ub3c4 \ud568\uaed8 \uace0\ub824\ud574\uc57c \ud55c\ub2e4. \ub9c8\uc6b0\uc2a4 \uc904\uae30\uc138\ud3ec \ubaa8\ub378\uacfc \ud615\uad11 \ub9ac\ud3ec\ud130\ub294 \uc778\uac04 \uc0dd\uccb4 \ud658\uacbd\uc744 \uc644\ubcbd\ud788 \uc7ac\ud604\ud558\uc9c0 \ubabb\ud558\ubbc0\ub85c, \uc77c\ubd80 \ubcc0\uc774\uc5d0 \ub300\ud574 \uc870\uc9c1 \ud2b9\uc774\uc801 \ubcf4\uc815\uc774 \ud544\uc694\ud560 \uc218 \uc788\ub2e4. \ub2e4\ub9cc \uc218\ucc9c \uba85 \uaddc\ubaa8\uc758 \ud658\uc790 \ub370\uc774\ud130\uc640\uc758 \uc0c1\uad00\uc131 \uac80\uc99d\uc740 \uc2e4\ud5d8 \uacb0\uacfc\uc758 \uc784\uc0c1\uc801 \uad00\ub828\uc131\uc744 \uc0c1\ub2f9 \ubd80\ubd84 \ub4b7\ubc1b\uce68\ud55c\ub2e4.<\/p>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\uc9c0\ud45c<\/th>\n<th>\uac12<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\ud3c9\uac00\ub41c \ub2e8\uc77c \uc5fc\uae30 \ub3cc\uc5f0\ubcc0\uc774 \uc218<\/td>\n<td>342\uac1c<\/td>\n<\/tr>\n<tr>\n<td>\uacfc\uac70 \uad00\ucc30\ub41c \ud56b\uc2a4\ud31f \ubcc0\uc774<\/td>\n<td>70\uac1c \uc774\uc0c1<\/td>\n<\/tr>\n<tr>\n<td>\ud658\uc790 \ub370\uc774\ud130 \ube44\uad50 \uaddc\ubaa8<\/td>\n<td>\uc218\ucc9c \uba85(\ud1b5\ud569 \uc554 \ub370\uc774\ud130\ubca0\uc774\uc2a4)<\/td>\n<\/tr>\n<tr>\n<td>\uac8c\uc7ac \ud559\uc220\uc9c0<\/td>\n<td>Nature Genetics<\/td>\n<\/tr>\n<tr>\n<td>\uc5f0\uad6c \uc790\uae08<\/td>\n<td>MRC, BBSRC<\/td>\n<\/tr>\n<\/tbody>\n<\/table><figcaption>\uc5f0\uad6c\uc758 \uc8fc\uc694 \uc218\uce58 \uc694\uc57d. \uc2e4\ud5d8\uc801 \uc804\uc218 \ud3c9\uac00(342\uac1c)\uc640 \ud658\uc790 \ub370\uc774\ud130 \uac80\uc99d(\uc218\ucc9c \uba85)\uc744 \uacb0\ud569\ud588\ub2e4.<\/figcaption><\/figure>\n<p>\uc704 \ud45c\ub294 \ubcf8 \uc5f0\uad6c\uc758 \ud575\uc2ec \uc218\uce58\ub4e4\uc744 \uac04\uacb0\ud788 \uc815\ub9ac\ud55c \uac83\uc774\ub2e4. \uc2e4\ud5d8\uc801 \uce21\uc815\uce58\uc640 \uc784\uc0c1 \ub370\uc774\ud130 \ube44\uad50\ub77c\ub294 2\ucd95 \uac80\uc99d\uc744 \ud1b5\ud574 \uacb0\uacfc\uc758 \uc2e0\ub8b0\uc131\uc744 \ub192\uc600\ub2e4\ub294 \uc810\uc774 \ud2b9\uc9d5\uc774\ub2e4. \ub2e4\ub9cc \ud45c\uc5d0 \uc81c\uc2dc\ub41c \ud658\uc790 \uaddc\ubaa8\ub294 \uc5ec\ub7ec \uacf5\uac1c \ub370\uc774\ud130\ubca0\uc774\uc2a4\ub97c \ud1b5\ud569\ud55c \uac12\uc73c\ub85c, \uac1c\ubcc4 \ucf54\ud638\ud2b8\ubcc4 \ucc28\uc774\ub294 \uc874\uc7ac\ud55c\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c \uacb0\uacfc \ubc1c\ud45c \uc9c1\ud6c4 \uc5f0\uad6c\ucc45\uc784\uc790\uc640 \ud559\uacc4\uc758 \ubc18\uc751\uc774 \uc774\uc5b4\uc84c\ub2e4. \ub2e4\uc74c \ubc1c\uc5b8\ub4e4\uc740 \uc5f0\uad6c \uc804\ud6c4 \ub9e5\ub77d\uc744 \ud568\uaed8 \uc18c\uac1c\ud55c\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\uc774 \uc0c8\ub85c\uc6b4 \uc9c0\ub3c4\ub294 \ud2b9\uc815 CTNNB1 \ub3cc\uc5f0\ubcc0\uc774\uac00 \uc554\uc758 \ud589\ub3d9 \uc591\uc0c1\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \uc608\uce21\ud558\ub294 \uac15\ub825\ud55c \ub3c4\uad6c\uac00 \ub420 \uac83\uc785\ub2c8\ub2e4.&#8221;<\/p>\n<p><cite>\uc564\ub4dc\ub958 \uc6b0\ub4dc \ubc15\uc0ac(\uc5d0\ub4e0\ubc84\ub7ec\ub300, \uc5f0\uad6c\ucc45\uc784\uc790)<\/cite><\/p><\/blockquote>\n<p>\uc6b0\ub4dc \ubc15\uc0ac\uc758 \uc5b8\uae09\uc740 \uc774\ubc88 \uc9c0\ub3c4\uac00 \uae30\ucd08\uc5f0\uad6c\ubfd0 \uc544\ub2c8\ub77c \uc784\uc0c1\uc801 \uc758\uc0ac\uacb0\uc815 \uc9c0\uc6d0\uae4c\uc9c0 \ud655\ub300 \uc801\uc6a9\ub420 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c\uc9c4\uc758 \uae30\ub300\ub97c \ubc18\uc601\ud55c\ub2e4. \uc5f0\uad6c\ud300\uc740 \uc9c0\ub3c4 \uae30\ubc18\uc758 \ubcc0\uc774 \ub4f1\uae09\uc774 \ud658\uc790 \uacc4\uce35\ud654 \ubc0f \uce58\ub8cc \uc120\ud0dd\uc5d0 \ud65c\uc6a9\ub420 \uc218 \uc788\uc74c\uc744 \uac15\uc870\ud588\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\uc791\uc740 \uc720\uc804\uc801 \ubcc0\ud654\uac00 \ub9e4\uc6b0 \ub2e4\ub978 \uc554 \ud589\ub3d9 \uc591\uc0c1\uc73c\ub85c \uc774\uc5b4\uc9c4\ub2e4\ub294 \uc810\uc744 \uba85\ud655\ud788 \ubcf4\uc5ec\uc900\ub2e4.&#8221;<\/p>\n<p><cite>Nature Genetics(\ub17c\ubb38 \uc694\uc9c0)<\/cite><\/p><\/blockquote>\n<p>\ud559\uc220\uc9c0\uc5d0 \uc2e4\ub9b0 \ub17c\ubb38 \uc694\uc9c0\ub294 \uc2e4\ud5d8\uc801 \ub370\uc774\ud130\uc640 \uc784\uc0c1 \uad00\ucc30\uc758 \uc77c\uce58\uc131\uc774 \uc5f0\uad6c\uc758 \ud575\uc2ec \uc99d\uac70\uc784\uc744 \uc694\uc57d\ud55c\ub2e4. \ud3b8\uc9d1\uc790 \ucf54\uba58\ud2b8\ub294 \uc5f0\uad6c\uc758 \ubc29\ubc95\ub860\uc801 \uc5c4\ubc00\uc131\uacfc \ub370\uc774\ud130 \uac80\uc99d\uc758 \ud3ed\uc744 \uadfc\uac70\ub85c \uc5f0\uad6c \uac00\uce58\ub97c \ud3c9\uac00\ud588\ub2e4.<\/p>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>CTNNB1\uc740 \u03b2-\uce74\ud14c\ub2cc\uc744 \uc554\ud638\ud654\ud558\ub294 \uc720\uc804\uc790\uba85\uc774\uba70, \u03b2-\uce74\ud14c\ub2cc\uc740 \uc138\ud3ec \ub0b4 \uc2e0\ud638\uc804\ub2ec(\ud2b9\ud788 Wnt \uacbd\ub85c)\uc5d0\uc11c \ud575\uc2ec \uc5ed\ud560\uc744 \ud55c\ub2e4. \uc774\ubc88 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ubaa8\ub4e0 \uac00\ub2a5\ud55c \ub2e8\uc77c \uc5fc\uae30 \uce58\ud658\uc744 \uc0dd\uc131\ud55c \ub4a4 \ud615\uad11 \uae30\ubc18 \ub9ac\ud3ec\ud130\ub85c \u03b2-\uce74\ud14c\ub2cc \uacbd\ub85c \ud65c\uc131\ub3c4\ub97c \uc815\ub7c9\ud588\ub2e4. \uc0ac\uc6a9\ub41c \ubaa8\ub378\uc740 \ub9c8\uc6b0\uc2a4 \uc904\uae30\uc138\ud3ec\ub85c\uc11c \uc778\uac04 \uc2e0\ud638\uc804\ub2ec \ud2b9\uc131\uc744 \uc0c1\ub2f9 \ubd80\ubd84 \ubc18\uc601\ud558\uc9c0\ub9cc, \uc870\uc9c1 \ud2b9\uc774\uc801 \uc694\uc18c\ub294 \ucd94\uac00 \ubcf4\uc815\uc774 \ud544\uc694\ud560 \uc218 \uc788\ub2e4. \ud658\uc790 \ub370\uc774\ud130 \uac80\uc99d\uc740 \uacf5\uac1c \uc554 \ub370\uc774\ud130\ubca0\uc774\uc2a4\uc758 \ub3cc\uc5f0\ubcc0\uc774 \ubd84\ud3ec\uc640 \uc2e4\ud5d8 \uc810\uc218 \uac04 \uc0c1\uad00\uc131 \ubd84\uc11d\uc73c\ub85c \uc218\ud589\ub410\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\ub9c8\uc6b0\uc2a4 \uc904\uae30\uc138\ud3ec \ubaa8\ub378\uc774 \uc778\uac04 \uc131\uccb4 \uc870\uc9c1\uc758 \ubaa8\ub4e0 \uc138\ud3ec\ud658\uacbd\uc744 \uc7ac\ud604\ud55c\ub2e4\uace0 \ub2e8\uc815\ud560 \uc218\ub294 \uc5c6\ub2e4. \uc77c\ubd80 \ubcc0\uc774\ub294 \uc778\uac04 \ud2b9\uc815 \uc870\uc9c1\uc5d0\uc11c \uc0c1\uc774\ud55c \ud6a8\uacfc\ub97c \ub0bc \uac00\ub2a5\uc131\uc774 \uc788\ub2e4.<\/li>\n<li>\ud658\uc790 \ub370\uc774\ud130\ub294 \uc5ec\ub7ec \ucf54\ud638\ud2b8\ub97c \ud1b5\ud569\ud55c \uacb0\uacfc\ub85c, \uac1c\ubcc4 \uc784\uc0c1\uad70(\uce58\ub8cc \uc774\ub825\u00b7\ubcd1\uae30 \ub4f1)\uc5d0 \ub530\ub978 \uc138\ubd80 \ucc28\uc774\ub294 \ucd94\uac00 \ubd84\uc11d\uc774 \ud544\uc694\ud558\ub2e4.<\/li>\n<li>\ub3cc\uc5f0\ubcc0\uc774 \ud65c\uc131\ub3c4\uc640 \uba74\uc5ed\uce58\ub8cc \ubc18\uc751 \uac04\uc758 \uc778\uacfc\uad00\uacc4\ub294 \uc544\uc9c1 \uc784\uc0c1\uc801 \uac80\uc99d\uc774 \ud544\uc694\ud558\uba70, \ud604\uc7ac\ub294 \uc0c1\uad00\uc131 \uc218\uc900\uc758 \uadfc\uac70\uac00 \uc8fc\ub97c \uc774\ub8ec\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 CTNNB1\uc758 \ud575\uc2ec \ubd80\uc704\uc5d0\uc11c \uac00\ub2a5\ud55c \ubaa8\ub4e0 \ub2e8\uc77c \uc5fc\uae30 \ub3cc\uc5f0\ubcc0\uc774\ub97c \uccb4\uacc4\uc801\uc73c\ub85c \ud3c9\uac00\ud574 \ubcc0\uc774\ubcc4 \uae30\ub2a5 \ucc28\uc774\ub97c \uc815\ub7c9\ud654\ud55c \uccab \ub300\uaddc\ubaa8 \uc2e4\ud5d8\uc801 \uc804\uc218\uc9c0\ub3c4\ub2e4. \uc218\ucc9c \uba85 \uaddc\ubaa8\uc758 \ud658\uc790 \ub370\uc774\ud130\uc640\uc758 \ube44\uad50 \uac80\uc99d\uc740 \uc2e4\ud5d8 \uacb0\uacfc\uc758 \uc784\uc0c1\uc801 \uad00\ub828\uc131\uc744 \ud655\ubcf4\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ubbf8\uac00 \ud06c\ub2e4.<\/p>\n<p>\uc2e4\ubb34\uc801\uc73c\ub85c\ub294 \ubcc0\uc774\ubcc4 \uae30\ub2a5 \uc810\uc218\uac00 \ud5a5\ud6c4 \uc784\uc0c1 \uc720\uc804\uc790 \ud310\ub3c5\u00b7\ud658\uc790 \uacc4\uce35\ud654\u00b7\uce58\ub8cc \uc120\ud0dd\uc758 \ubcf4\uc870 \uc9c0\ud45c\ub85c \ud65c\uc6a9\ub420 \uc218 \uc788\ub2e4. \ub2e4\ub9cc \ubaa8\ub378\uc758 \ud55c\uacc4\uc640 \ud658\uc790 \ucf54\ud638\ud2b8\uc758 \uc774\uc9c8\uc131\uc740 \ucd94\uac00 \uc5f0\uad6c\ub85c \ubcf4\uc644\ud574\uc57c \ud55c\ub2e4. \uc5f0\uad6c\uc9c4\uacfc \ud6c4\uc18d \uc784\uc0c1\uc2dc\ud5d8 \uacb0\uacfc\ub97c \ud1b5\ud574 \ubcf8 \uc9c0\ub3c4\uc758 \uc801\uc6a9 \ubc94\uc704\uc640 \ud55c\uacc4\uac00 \ubcf4\ub2e4 \uba85\ud655\ud574\uc9c8 \uac83\uc774\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.technologyreview.kr\/deeptech\/%EC%98%81%EA%B5%AD-%EC%97%90%EB%93%A0%EB%B2%84%EB%9F%AC%EB%8C%80-%EC%A3%BC%EC%9A%94-%EC%95%94-%EC%9C%A0%EC%A0%84%EC%9E%90-342%EA%B0%80%EC%A7%80-%EB%8F%8C%EC%97%B0%EB%B3%80%EC%9D%B4-%ED%9A%A8%EA%B3%BC\/\" target=\"_blank\" rel=\"noopener\">MIT \ud14c\ud06c\ub180\ub85c\uc9c0 \ub9ac\ubdf0<\/a> &#8211; \uc5b8\ub860 \ubcf4\ub3c4(\uc6d0\ubb38 \uae30\uc0ac)<\/li>\n<li><a href=\"https:\/\/www.nature.com\/natgenet\/\" target=\"_blank\" rel=\"noopener\">Nature Genetics<\/a> &#8211; \ud559\uc220\uc9c0(\ub17c\ubb38 \uac8c\uc7ac\ucc98, \ub17c\ubb38\ubcf8\ubb38 \ucc38\uc870)<\/li>\n<li><a href=\"https:\/\/www.ukri.org\/councils\/mrc\/\" target=\"_blank\" rel=\"noopener\">Medical Research Council (MRC)<\/a> &#8211; \uc5f0\uad6c \uc790\uae08 \uc9c0\uc6d0(\uacf5\uc2dd \uae30\uad00)<\/li>\n<li><a href=\"https:\/\/www.ukri.org\/councils\/bbsrc\/\" target=\"_blank\" rel=\"noopener\">Biotechnology and Biological Sciences Research Council (BBSRC)<\/a> &#8211; \uc5f0\uad6c \uc790\uae08 \uc9c0\uc6d0(\uacf5\uc2dd \uae30\uad00)<\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>2026\ub144 2\uc6d4 6\uc77c \u2014 \uc601\uad6d \uc5d0\ub4e0\ubc84\ub7ec \ub300\ud559\uad50 \uc5f0\uad6c\ud300\uc774 \uc554\uc5d0\uc11c \ube48\ubc1c\ud558\ub294 \uc720\uc804\uc790 CTNNB1\uc758 \ud575\uc2ec \ubd80\uc704\uc5d0\uc11c \uac00\ub2a5\ud55c 342\uac00\uc9c0 \ub2e8\uc77c \uc5fc\uae30 \ub3cc\uc5f0\ubcc0\uc774\ub97c \ubaa8\ub450 \uc2e4\ud5d8\uc801\uc73c\ub85c \uac80\uc0ac\ud574, \uac01 \ubcc0\uc774\uac00 \u03b2-\uce74\ud14c\ub2cc \uc2e0\ud638\ub97c \uc5bc\ub9c8\ub098 \uac15\ud558\uac8c \ud65c\uc131\ud654\ud558\ub294\uc9c0 \uce21\uc815\ud55c \uc804\uc218 \uc9c0\ub3c4\ub97c \ubc1c\ud45c\ud588\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \ub9c8\uc6b0\uc2a4 \uc904\uae30\uc138\ud3ec \ubaa8\ub378\uacfc \ucca8\ub2e8 \uc720\uc804\uccb4 \ud3b8\uc9d1\u00b7\ud615\uad11 \ubd84\uc11d\uc744 \ud65c\uc6a9\ud574 \ub3cc\uc5f0\ubcc0\uc774\ubcc4 \ud65c\uc131\ub3c4 \uc810\uc218\ub97c \uc0b0\ucd9c\ud558\uace0, \uc218\ucc9c \uba85\uc758 \uc554 \ud658\uc790 \uc720\uc804\uc790 \ub370\uc774\ud130\uc640 \ube44\uad50\ud574 \uc9c0\ub3c4\uc758 \uc608\uce21\ub825\uc774 &#8230; <a title=\"\uc5d0\ub4e0\ubc84\ub7ec\ub300, \uc8fc\uc694 \uc554 \uc720\uc804\uc790 342\uac00\uc9c0 \ub3cc\uc5f0\ubcc0\uc774 \ud6a8\uacfc \uc644\uc804 \ub9e4\ud551 \uc131\uacf5\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/edinburgh-ctnnb1-342-variants-map\/\" 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