{"id":9469,"date":"2026-03-04T12:08:13","date_gmt":"2026-03-04T03:08:13","guid":{"rendered":"https:\/\/readtrends.com\/ko\/single-cell-aging-atlas\/"},"modified":"2026-03-04T12:08:13","modified_gmt":"2026-03-04T03:08:13","slug":"single-cell-aging-atlas","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/single-cell-aging-atlas\/","title":{"rendered":"\uc6b0\ub9ac \ubab8\uc740 \uc5b4\ub5bb\uac8c \ub299\ub098: 21\uac1c \uc7a5\uae30\u00b7700\ub9cc \uc138\ud3ec \ub2e8\uc77c\uc138\ud3ec \uc544\ud2c0\ub77c\uc2a4 \uacf5\uac1c"},"content":{"rendered":"<article>\n<p><strong>\ud575\uc2ec \uc694\uc57d<\/strong><\/p>\n<p>\ubbf8\uad6d \ub85d\ud3a0\ub7ec\ub300 \uc8fc\ub2c8\uc6e8 \ucc28\uc624 \uad50\uc218\ud300\uc774 \ud559\uc220\uc9c0 \uc0ac\uc774\uc5b8\uc2a4\uc5d0 21\uac1c \uc7a5\uae30\uc5d0\uc11c \uc57d 700\ub9cc \uac1c \uc138\ud3ec\ub97c \ub2e8\uc77c\uc138\ud3ec \uc218\uc900\uc73c\ub85c \ubd84\uc11d\ud55c \uacb0\uacfc\ub97c \ubcf4\uace0\ud588\ub2e4. \uc5f0\uad6c\ub294 \uc0dd\ud6c4 1\uac1c\uc6d4\u00b75\uac1c\uc6d4\u00b721\uac1c\uc6d4\uc758 \uc0dd\uc950 32\ub9c8\ub9ac\ub97c \ub300\uc0c1\uc73c\ub85c \uc9c4\ud589\ub410\uc73c\uba70, \ub178\ud654 \uc2e0\ud638\uac00 \uc608\uc0c1\ubcf4\ub2e4 \uc774\ub974\uac8c \uc2dc\uc791\ub418\uace0 \uc5ec\ub7ec \uc7a5\uae30\uc5d0\uc11c \ub3d9\uae30\ud654\ub41c \ubc29\uc2dd\uc73c\ub85c \uc9c4\ud589\ub41c\ub2e4\ub294 \uacb0\ub860\uc744 \uc81c\uc2dc\ud55c\ub2e4. \ub610\ud55c \uc138\ud3ec \uc720\ud615 \uad6c\uc131 \uc790\uccb4\uac00 \uc7ac\ud3b8\ub418\ub294 \ud604\uc0c1\uacfc \uc131\ubcc4\uc5d0 \ub530\ub978 \ucc28\uc774\ub97c \ud655\uc778\ud588\ub2e4. \uc5f0\uad6c \uacb0\uacfc\uc640 \ub370\uc774\ud130\ub294 \uacf5\uac1c \ud50c\ub7ab\ud3fc\uc744 \ud1b5\ud574 \uc5f0\uad6c\uc790\ub4e4\uc5d0\uac8c \uc81c\uacf5\ub41c\ub2e4.<\/p>\n<p><strong>\ud575\uc2ec \uc0ac\uc2e4<\/strong><\/p>\n<ul>\n<li>\ubd84\uc11d \ub300\uc0c1\uc740 \uc0dd\ud6c4 1\uac1c\uc6d4(\uc80a\uc740 \uc131\uccb4), 5\uac1c\uc6d4(\uc911\ub144), 21\uac1c\uc6d4(\ub178\ub144)\uc758 \uc0dd\uc950 32\ub9c8\ub9ac\uc5d0\uc11c \ucc44\ucde8\ud55c 21\uac1c \uc870\uc9c1\uc73c\ub85c, \ucd1d \uc57d 700\ub9cc \uac1c \uc138\ud3ec\ub97c \ud3ec\ud568\ud55c\ub2e4.<\/li>\n<li>\ub2e8\uc77c\uc138\ud3ec ATAC-seq\ub97c \uc774\uc6a9\ud574 \uc138\ud3ec \ub0b4 \uc720\uc804\uccb4 \uc811\uadfc\uc131 \ubcc0\ud654\ub97c \uce21\uc815\ud588\uace0, 1,800\uac1c \uc774\uc0c1\uc758 \uc11c\ub85c \ub2e4\ub978 \uc138\ud3ec \uc544\ud615\uc744 \ubd84\ub958\ud588\ub2e4.<\/li>\n<li>\uc138\ud3ec \uc218 \uc790\uccb4\uc758 \ubcc0\ud654\uac00 \ub69c\ub837\ud558\uc5ec \uc804\uccb4 \uc138\ud3ec \uc720\ud615\uc758 \uc57d 4\ubd84\uc758 1\uc5d0\uc11c \ub098\uc774\uc640 \ud568\uaed8 \uc720\uc758\ud55c \uc99d\uac10\uc774 \uad00\ucc30\ub410\ub2e4; \uc608\ub85c \uc77c\ubd80 \uadfc\uc721\u00b7\uc2e0\uc7a5 \uc138\ud3ec\ub294 \uac10\uc18c\ud588\uace0 \uba74\uc5ed\uc138\ud3ec\ub294 \uc99d\uac00\ud588\ub2e4.<\/li>\n<li>\uc0dd\ud6c4 5\uac1c\uc6d4(\uc911\ub144) \ub2e8\uacc4\uc5d0\uc11c \uc774\ubbf8 \ud2b9\uc815 \uc138\ud3ec \uc9d1\ub2e8\uc758 \uac10\uc18c\uac00 \uc2dc\uc791\ub3fc, \ub178\ud654\uac00 \ub178\ub144\uae30 \ub3cc\uc5f0 \ubc1c\uc0dd\ud558\ub294 \ud604\uc0c1\uc774 \uc544\ub2c8\ub77c \uc810\uc9c4\uc801 \uc5f0\uc18d \uacfc\uc815\uc784\uc744 \uc2dc\uc0ac\ud55c\ub2e4.<\/li>\n<li>\uc57d 130\ub9cc \uac1c \uc720\uc804\uccb4 \uc601\uc5ed\uc744 \uc870\uc0ac\ud574 \uadf8\uc911 \uc57d 30\ub9cc \uac1c\uc5d0\uc11c \ub178\ud654 \uad00\ub828 \ubcc0\ud654\uac00 \ud655\uc778\ub418\uc5c8\uace0, \uc57d 1,000\uac1c \uc601\uc5ed\uc740 \uc5ec\ub7ec \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \uacf5\ud1b5\uc801\uc73c\ub85c \ubcc0\ud654\ub97c \ubcf4\uc600\ub2e4.<\/li>\n<li>\ub178\ud654 \uad00\ub828 \ubcc0\ud654\uc758 \uc57d 40%\uac00 \uc131\ubcc4\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc84c\uace0, \ud2b9\ud788 \uc5ec\uc131\uc5d0\uc11c \uba74\uc5ed \ud65c\uc131\ud654 \uc2e0\ud638\uac00 \ub354 \uad11\ubc94\uc704\ud558\uac8c \uad00\ucc30\ub418\uc5c8\ub2e4.<\/li>\n<li>\uc5f0\uad6c\uc9c4\uc740 \uc0ac\uc774\ud1a0\uce74\uc778 \ub4f1 \ud608\uc911 \uc21c\ud658 \ubb3c\uc9c8\uc774 \uc7a5\uae30 \uac04 \ub3d9\uae30\ud654\uc5d0 \uad00\uc5ec\ud560 \uac00\ub2a5\uc131\uc744 \uc81c\uae30\ud588\uc73c\uba70, \ub370\uc774\ud130\ub294 \uacf5\uac1c \ud50c\ub7ab\ud3fc(epiage.net)\uc744 \ud1b5\ud574 \uc81c\uacf5\ub41c\ub2e4.<\/li>\n<\/ul>\n<p><strong>\uc0ac\uac74 \ubc30\uacbd<\/strong><\/p>\n<p>\uc804\ud1b5\uc801\uc73c\ub85c \ub178\ud654\ub294 \uc138\ud3ec\u00b7\uc870\uc9c1\uc758 \uae30\ub2a5 \uc800\ud558\ub85c \uc774\ud574\ub3fc \uc654\uace0, \uc784\uc0c1\uc801 \uc99d\uc0c1(\uc8fc\ub984, \uadfc\ub825 \uc800\ud558, \uc9c8\ubcd1 \uc99d\uac00)\uc740 \uc8fc\ub85c \uc5f0\ub839\uacfc \uc5f0\uad00\ub3fc \uc124\uba85\ub410\ub2e4. \uadf8\ub7ec\ub098 &#8216;\uc5b8\uc81c&#8217;, &#8216;\uc5b4\ub514\uc11c&#8217;\ubd80\ud130 \ub178\ud654\uac00 \uc2dc\uc791\ub418\ub294\uc9c0, \uadf8\ub9ac\uace0 \uc7a5\uae30\ubcc4\ub85c \uac1c\ubcc4\uc801\uc73c\ub85c \uc77c\uc5b4\ub098\ub294\uc9c0 \uc804\uc2e0\uc801\uc73c\ub85c \uc870\uc728\ub418\ub294\uc9c0\uc5d0 \ub300\ud55c \uc815\ubc00\ud55c \uc9c0\ub3c4\ub294 \ubd80\uc871\ud588\ub2e4. \ucd5c\uadfc \ub2e8\uc77c\uc138\ud3ec \uae30\uc220\uc758 \ubc1c\ub2ec\ub85c \uac1c\ubcc4 \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \uc720\uc804\uc790\uc758 \ubc1c\ud604\uacfc \uc720\uc804\uccb4 \uc0c1\ud0dc\ub97c \ub4e4\uc5ec\ub2e4\ubcfc \uc218 \uc788\uac8c \ub418\uc5c8\uace0, \uc774\ub97c \uc804\uccb4 \uc7a5\uae30\ub9dd\uc73c\ub85c \ud655\uc7a5\ud558\ub824\ub294 \uc2dc\ub3c4\uac00 \ud65c\ubc1c\ud574\uc84c\ub2e4. \ub3d9\ubb3c \ubaa8\ub378 \uc5f0\uad6c\ub294 \uc778\uac04\uacfc \uc9c1\uc811 \uc77c\ub300\uc77c \ub300\uc751\uc740 \uc5b4\ub835\uc9c0\ub9cc, \uc0dd\uc560 \ub2e8\uacc4\ubcc4 \ubcc0\ud654\ub97c \uccb4\uacc4\uc801\uc73c\ub85c \ube44\uad50\ud560 \uc218 \uc788\ub294 \uc7a5\uc810\uc774 \uc788\uc5b4 \ub178\ud654 \uba54\ucee4\ub2c8\uc998 \uc5f0\uad6c\uc758 \ud575\uc2ec \ub3c4\uad6c\ub85c \ud65c\uc6a9\ub3fc \uc654\ub2e4.<\/p>\n<p>\ub610\ud55c \ub178\ud654 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uba74\uc5ed\uacc4\uc758 \ubcc0\ud654\uc640 \uc5fc\uc99d\uc131 \uc2e0\ud638\uc758 \uc5ed\ud560\uc774 \uc911\uc694\ud558\uac8c \uc81c\uae30\ub3fc \uc654\uc73c\uba70, \uc21c\ud658 \uc778\uc790\uc758 \ubcc0\ud654\uac00 \uc6d0\uaca9 \uc7a5\uae30\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4\ub294 \uac00\uc124\uc774 \ubc18\ubcf5\uc801\uc73c\ub85c \uc81c\uc2dc\ub3fc \uc654\ub2e4. \uacfc\uac70 \uc5f0\uad6c\ub4e4\uc740 \uc8fc\ub85c \ud2b9\uc815 \uc7a5\uae30\ub098 \uc870\uc9c1\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd94\uc5c8\uc73c\ub098, \uc774\ubc88 \uc5f0\uad6c\ub294 \ub2e4\uae30\uad00\uc744 \ud6a1\ub2e8\ud558\ub294 \ub2e8\uc77c\uc138\ud3ec \uc544\ud2c0\ub77c\uc2a4\ub97c \uad6c\ucd95\ud574 \uc7a5\uae30 \uac04 \uacf5\ud1b5 \uc2e0\ud638\uc640 \ucc28\uc774\uc810\uc744 \ub3d9\uc2dc\uc5d0 \ud3c9\uac00\ud588\ub2e4. \uc774\ub7ec\ud55c \uc804\uc2e0\uc801 \uad00\uc810\uc740 \ub098\uc774 \uad00\ub828 \uc9c8\ud658\uc758 \uc608\ubc29\u00b7\uce58\ub8cc \uc804\ub7b5\uc744 \ub2e4\uac01\ud654\ud558\ub294 \ub370 \uae30\ucd08 \uc790\ub8cc\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\ub2e4.<\/p>\n<p><strong>\uc8fc\uc694 \uc0ac\uac74<\/strong><\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uc0dd\uc950 32\ub9c8\ub9ac\uc5d0\uc11c 21\uac1c \uc870\uc9c1\uc744 \ud45c\uc900\ud654\ub41c \ubc29\uc2dd\uc73c\ub85c \uc218\uc9d1\ud55c \ub4a4, \ub2e8\uc77c\uc138\ud3ec ATAC-seq\uc73c\ub85c \uc720\uc804\uccb4 \uc811\uadfc\uc131 \ud328\ud134\uc744 \uce21\uc815\ud588\ub2e4. \ubd84\uc11d \uacb0\uacfc, 1,800\uac1c\uac00 \ub118\ub294 \uc138\ud3ec \uc544\ud615\uc744 \ud655\uc778\ud588\uace0 \uc774 \uc911 \uc77c\ubd80\ub294 \uc774\uc804\uc5d0 \ucda9\ubd84\ud788 \uae30\uc220\ub418\uc9c0 \uc54a\uc558\ub358 \ud76c\uadc0 \uc138\ud3ec \uc9d1\ub2e8\uc774\uc5c8\ub2e4. \uc5f0\ub839\uc5d0 \ub530\ub978 \ube44\uad50\uc5d0\uc11c \uc804\uccb4 \uc138\ud3ec \uad6c\uc131\uc758 \uc57d 25%\uac00 \uc218\uc801 \ubcc0\ud654\ub97c \ubcf4\uc600\uc73c\uba70, \ud2b9\ud788 \uba74\uc5ed\uc138\ud3ec\uc758 \uc99d\uac00\ub294 \uac70\uc758 \ubaa8\ub4e0 \uc7a5\uae30\uc5d0\uc11c \uacf5\ud1b5\uc801\uc73c\ub85c \uad00\ucc30\ub410\ub2e4.<\/p>\n<p>\uc5f0\uad6c\ub294 \uc911\ub144 \ub2e8\uacc4(\uc0dd\ud6c4 5\uac1c\uc6d4)\uc5d0\uc11c \uc774\ubbf8 \uac00\uc2dc\uc801 \ubcc0\ud654\uac00 \uc2dc\uc791\ub41c \uc810\uc744 \uac15\uc870\ud55c\ub2e4. \uc774\ub294 \ub178\ud654\uac00 \ubc1c\ub2ec \uacfc\uc815\uacfc \uc5f0\uc18d\uc120\uc0c1\uc5d0 \uc788\uc73c\uba70, \ud2b9\uc815 \uc138\ud3ec\uad70\uc758 \uc18c\uc2e4\uc774\ub098 \uc99d\uc2dd\uc774 \uc77c\ucc0d\ubd80\ud130 \ucd95\uc801\ub418\uc5b4 \uc7a5\uae30 \uae30\ub2a5 \ubcc0\ud654\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4. \ud765\ubbf8\ub86d\uac8c\ub3c4 \uc11c\ub85c \ub2e4\ub978 \uc7a5\uae30\uc5d0\uc11c \uc720\uc0ac\ud55c \uc138\ud3ec \uc0c1\ud0dc \ubcc0\ud654\uac00 \ub3d9\uc2dc\ub2e4\ubc1c\uc801\uc73c\ub85c \ub098\ud0c0\ub098\ub294 &#8216;\ub3d9\uae30\ud654&#8217; \ud328\ud134\uc774 \ud3ec\ucc29\ub410\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774 \ub3d9\uae30\ud654\uc5d0 \ud608\uc911 \uc21c\ud658\uc778\uc790, \uc0ac\uc774\ud1a0\uce74\uc778 \ub610\ub294 \uc804\uc2e0\uc801 \ub300\uc0ac \ubcc0\ud654\uac00 \uad00\uc5ec\ud560 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud588\ub2e4.<\/p>\n<p>\ub610\ud55c \uc720\uc804\uccb4 \uc218\uc900 \ubd84\uc11d\uc5d0\uc11c \uc57d 30\ub9cc \uac1c\uc758 \ub178\ud654 \uad00\ub828 \uc601\uc5ed\uc774 \uad00\ucc30\ub410\uace0, \uadf8\uc911 \uc57d 1,000\uac1c \uc601\uc5ed\uc740 \ub2e4\uc591\ud55c \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \uacf5\ud1b5\uc801\uc73c\ub85c \ubcc0\ud654\ub97c \ubcf4\uc600\ub2e4. \uc774\ub4e4 \uacf5\ud1b5 \uc601\uc5ed\uc740 \uba74\uc5ed\u00b7\uc5fc\uc99d \ubc18\uc751 \ubc0f \uc904\uae30\uc138\ud3ec \uc720\uc9c0\uc640 \uad00\ub828\ub41c \uc870\uc808 \ubd80\uc704\uc640 \uc5f0\uacb0\ub418\uc5b4 \uc788\uc5b4, \ub178\ud654\uac00 \ubb34\uc791\uc704 \uc190\uc0c1\uc774 \uc544\ub2c8\ub77c \ud2b9\uc815 \uc870\uc808 \ud56b\uc2a4\ud3ff\uc5d0\uc11c \ubc18\ubcf5\uc801\uc73c\ub85c \uc77c\uc5b4\ub0a0 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc900\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc774\ub7ec\ud55c \uacb0\uacfc\uac00 \ud45c\uc801 \uce58\ub8cc \uac1c\ubc1c\uc758 \ucd9c\ubc1c\uc810\uc774 \ub420 \uc218 \uc788\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n<p><strong>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/strong><\/p>\n<p>\uccab\uc9f8, \ub178\ud654\uc758 \uc870\uae30 \uc2dc\uc791\uacfc \uc810\uc9c4\uc801 \uc9c4\ud589\uc740 &#8216;\ub178\ub144\uae30\uc758 \uae09\uaca9\ud55c \uc1e0\ud1f4&#8217;\ub77c\ub294 \uc9c1\uad00\uc744 \uc7ac\uace0\ud558\uac8c \ud55c\ub2e4. \uc911\ub144 \ub2e8\uacc4\uc5d0\uc11c \uc774\ubbf8 \uc138\ud3ec \uad6c\uc131\uc758 \ubcc0\ud654\uac00 \uc2dc\uc791\ub41c\ub2e4\uba74, \uc608\ubc29\uc801 \uac1c\uc785 \uc2dc\uc810\ub3c4 \uc774\ub97c \ubc18\uc601\ud574 \uc55e\ub2f9\uaca8\uc57c \ud560 \uac00\ub2a5\uc131\uc774 \ucee4\uc9c4\ub2e4. \ub458\uc9f8, \uc7a5\uae30 \uac04 \ub3d9\uae30\ud654 \ubc1c\uacac\uc740 \ub178\ud654\ub97c \uc7a5\uae30\ubcc4\ub85c \ubd84\ub9ac\ud574 \uce58\ub8cc\ud558\ub294 \uc811\uadfc\uc758 \ud55c\uacc4\ub97c \ubcf4\uc5ec\uc900\ub2e4. \uc804\uc2e0\uc744 \ud1b5\ud574 \uc791\ub3d9\ud558\ub294 \uc2e0\ud638\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\ub294 \uc804\ub7b5, \uc608\ucee8\ub300 \ud608\uc911 \uc0ac\uc774\ud1a0\uce74\uc778\uc774\ub098 \ub300\uc0ac \uc778\uc790\ub97c \uc870\uc808\ud558\ub294 \uce58\ub8cc\ubc95\uc774 \uc758\ubbf8\ub97c \uac00\uc9c8 \uc218 \uc788\ub2e4.<\/p>\n<p>\uc14b\uc9f8, \uc131\ubcc4 \ucc28\uc774\ub294 \ub9de\ucda4\ud615 \uc811\uadfc\uc758 \ud544\uc694\uc131\uc744 \ubd80\uac01\ud55c\ub2e4. \uc5f0\uad6c\uc5d0\uc11c \uad00\ucc30\ub41c \uc57d 40%\uc758 \uc131\ubcc4 \ucc28\uc774\ub294 \uc784\uc0c1\uc2dc\ud5d8 \uc124\uacc4\uc640 \uce58\ub8cc \ud45c\uc801 \uc120\uc815\uc5d0\uc11c \ub0a8\ub140 \ucc28\uc774\ub97c \uace0\ub824\ud574\uc57c \ud55c\ub2e4\ub294 \uadfc\uac70\ub97c \uc81c\uacf5\ud55c\ub2e4. \ub137\uc9f8, \uc720\uc804\uccb4 \uc870\uc808 \ubd80\uc704\uc758 \uacf5\ud1b5\uc801 \ubcc0\ud654\ub294 \ub178\ud654 \uad00\ub828 \ubc14\uc774\uc624\ub9c8\ucee4 \ubc1c\uad74\uacfc \uc57d\ubb3c \ud45c\uc801 \ubc1c\uacac\uc5d0 \uc2e4\uc9c8\uc801 \ub2e8\uc11c\ub97c \uc900\ub2e4. \ub2e4\ub9cc \uc774\ub7ec\ud55c \uae30\uc804\uacfc \uce58\ub8cc \uac00\ub2a5\uc131\uc740 \uc0dd\uc950 \ubaa8\ub378\uc5d0\uc11c \ub3c4\ucd9c\ub41c \uacb0\uacfc\uc774\ubbc0\ub85c \uc778\uac04\uc5d0\uc11c\uc758 \uc7ac\ud604\uc131\uacfc \uc778\uacfc\uad00\uacc4 \uaddc\uba85\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p><strong>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/strong><\/p>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\ud56d\ubaa9<\/th>\n<th>\uc218\uce58\/\ub0b4\uc6a9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\ub300\uc0c1 \ub3d9\ubb3c<\/td>\n<td>\uc0dd\uc950 32\ub9c8\ub9ac (1m, 5m, 21m)<\/td>\n<\/tr>\n<tr>\n<td>\uc870\uc9c1 \uc218<\/td>\n<td>21\uac1c \uc7a5\uae30<\/td>\n<\/tr>\n<tr>\n<td>\uc138\ud3ec \uc218<\/td>\n<td>\uc57d 700\ub9cc \uac1c<\/td>\n<\/tr>\n<tr>\n<td>\ubd84\ub958\ub41c \uc138\ud3ec \uc544\ud615<\/td>\n<td>1,800\uac1c \uc774\uc0c1<\/td>\n<\/tr>\n<tr>\n<td>\uc870\uc0ac \uc720\uc804\uccb4 \uc601\uc5ed<\/td>\n<td>\uc57d 130\ub9cc \uac1c (\ubcc0\ud654 \uad00\ucc30 \uc57d 30\ub9cc \uac1c)<\/td>\n<\/tr>\n<\/tbody>\n<\/table><figcaption>\uc5f0\uad6c\uc758 \ud575\uc2ec \uc218\uce58 \uc694\uc57d. \uc0dd\uc950 \ubaa8\ub378 \uae30\ubc18 \ub300\uaddc\ubaa8 \ub2e8\uc77c\uc138\ud3ec ATAC-seq \ubd84\uc11d\uc774\ub2e4.<\/figcaption><\/figure>\n<p>\uc704 \ud45c\ub294 \uc5f0\uad6c\uc5d0\uc11c \ubcf4\uace0\ud55c \ud575\uc2ec \uc218\uce58\ub97c \uc815\ub9ac\ud55c \uac83\uc774\ub2e4. \ud45c\uc5d0 \ub098\ud0c0\ub09c \uc22b\uc790\ub294 \uc0dd\uc950 \ubaa8\ub378\uc5d0\uc11c \uc5bb\uc740 \uacb0\uacfc\uc774\uba70 \uc5f0\uad6c\uc9c4\ub3c4 \uc778\uac04\uacfc\uc758 \uc9c1\uc811\uc801\uc778 1:1 \ub300\uc751\uc740 \uc5b4\ub835\ub2e4\uace0 \uba85\uc2dc\ud588\ub2e4. \ub530\ub77c\uc11c \uc784\uc0c1 \uc801\uc6a9\uc774\ub098 \uc778\uac04\uc758 \uc5f0\ub839\ub300 \ub300\uc751\uc740 \ubcc4\ub3c4 \uac80\uc99d\uc774 \uc694\uad6c\ub41c\ub2e4.<\/p>\n<p><strong>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/strong><\/p>\n<p>\uc5f0\uad6c\uc758 \uc8fc\uc694 \uacb0\ub860\uacfc \uacf5\uac1c\uc5d0 \ub300\ud574 \uc5f0\uad6c\uc9c4\uc740 \uc5f0\uad6c\uc758 \uc758\uc758\uc640 \ud55c\uacc4\ub97c \ub3d9\uc2dc\uc5d0 \uc124\uba85\ud588\ub2e4.<\/p>\n<blockquote>\n<p>\uc774\ubc88 \uc544\ud2c0\ub77c\uc2a4\ub294 \ub178\ud654\uc758 \uc2dc\u00b7\uacf5\uac04\uc801 \ud328\ud134\uc744 \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \ubcf4\uc5ec\uc8fc\uba70, \ub178\ud654 \uc5f0\uad6c\uc758 \ub370\uc774\ud130 \uc778\ud504\ub77c\ub97c \ud06c\uac8c \ud655\uc7a5\ud55c\ub2e4.<\/p>\n<p><cite>\uc8fc\ub2c8\uc6e8 \ucc28\uc624 \uc5f0\uad6c\ud300(\ub85d\ud3a0\ub7ec\ub300, \uacf5\uc2dd \ubc1c\ud45c)<\/cite><\/p><\/blockquote>\n<p>\ud574\ub2f9 \ub370\uc774\ud130 \uacf5\uac1c\ub294 \ub2e4\ub978 \uc5f0\uad6c\uc790\ub4e4\uc774 \ucd94\uac00 \ubd84\uc11d\uc744 \ud1b5\ud574 \uae30\uc804 \uaddc\uba85\uacfc \ud45c\uc801 \ubc1c\uad74\uc5d0 \ucc38\uc5ec\ud560 \uc218 \uc788\uac8c \ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \ud658\uc601\ubc1b\uace0 \uc788\ub2e4.<\/p>\n<blockquote>\n<p>\ub370\uc774\ud130 \uacf5\uac1c\ub294 \uacf5\ub3d9 \uac80\uc99d\uacfc \uc0c8\ub85c\uc6b4 \uac00\uc124 \uc0dd\uc131\uc5d0 \uc911\uc694\ud55c \ucd9c\ubc1c\uc810\uc774 \ub41c\ub2e4. \uadf8\ub7ec\ub098 \uc0dd\uc950 \ubaa8\ub378 \uacb0\uacfc\ub97c \uc778\uac04 \uc784\uc0c1\uc5d0 \uc9c1\uc811 \uc801\uc6a9\ud558\uae30 \uc804\uc5d0 \uad50\ucc28 \uc885 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p><cite>\uc5f0\uad6c \uacf5\uac1c \ud50c\ub7ab\ud3fc \ubc0f \uc5f0\uad6c\uc790 \ubc18\uc751(\ud559\uacc4)<\/cite><\/p><\/blockquote>\n<p>\ub300\uc911\uacfc \uc784\uc0c1 \uc5f0\uad6c\uc790\ub4e4\uc740 \uc131\ubcc4 \ucc28\uc774\uc640 \ub3d9\uae30\ud654\ub41c \uc7a5\uae30 \ubcc0\ud654\ub97c \uc8fc\ubaa9\ud558\uba70 \ud6c4\uc18d \uc5f0\uad6c\ub97c \uc694\uad6c\ud558\ub294 \ubaa9\uc18c\ub9ac\ub97c \ub0c8\ub2e4.<\/p>\n<blockquote>\n<p>\uc131\ubcc4 \ucc28\uc774\ub294 \uc784\uc0c1\uc801 \uad00\ucc30\uacfc\ub3c4 \uc5f0\uacb0\ub420 \uc218 \uc788\uc5b4, \ud5a5\ud6c4 \ub9de\ucda4\ud615 \uc608\ubc29\u00b7\uce58\ub8cc \uc804\ub7b5 \uc124\uacc4\uc5d0 \uc720\uc6a9\ud55c \ub2e8\uc11c\uac00 \ub420 \uac83\uc774\ub2e4.<\/p>\n<p><cite>\ud559\uacc4 \uc804\ubb38\uac00(\uc885\ud569 \uc758\uacac)<\/cite><\/p><\/blockquote>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>\ub2e8\uc77c\uc138\ud3ec ATAC-seq\ub294 \uac1c\ubcc4 \uc138\ud3ec \ub0b4\uc5d0\uc11c \uc5fc\uc0c9\uc9c8 \uc811\uadfc\uc131\uc744 \uce21\uc815\ud574 \uc5b4\ub5a4 \uc720\uc804\uc790 \uc870\uc808 \ubd80\uc704\uac00 \uac1c\ubc29\ub3fc \uc788\ub294\uc9c0\ub97c \ud655\uc778\ud558\ub294 \uae30\ubc95\uc774\ub2e4. \uc5fc\uc0c9\uc9c8\uc774 \uc5f4\ub824 \uc788\uc73c\uba74 \ud574\ub2f9 \uc720\uc804\uc790 \ubc1c\ud604\uc774 \uc77c\uc5b4\ub0a0 \uac00\ub2a5\uc131\uc774 \ub192\uc544, \uc138\ud3ec \uc0c1\ud0dc\uc640 \uae30\ub2a5 \uc900\ube44\uc131\uc744 \ucd94\uc815\ud560 \uc218 \uc788\ub2e4. \uc774 \ubc29\ubc95\uc740 \uc804\ud1b5\uc801 \uc804\uc0ac\uccb4 \ubd84\uc11d(RNA-seq)\uacfc \ubcf4\uc644\uc801\uc73c\ub85c \uc0ac\uc6a9\ub418\uba70, \uc138\ud3ec \uc720\ud615 \ubd84\ub958\uc640 \uc870\uc808 \uc694\uc18c\uc758 \uc5f0\ub839 \uad00\ub828 \ubcc0\ud654\ub97c \ub3d9\uc2dc\uc5d0 \ud30c\uc545\ud558\ub294 \ub370 \uc720\ub9ac\ud558\ub2e4. \uc544\ud2c0\ub77c\uc2a4\ub294 \ub2e4\uc591\ud55c \uc870\uc9c1\uc5d0\uc11c \uc5bb\uc740 \ub2e8\uc77c\uc138\ud3ec \ub370\uc774\ud130\ub97c \ud1b5\ud569\ud574 \uc138\ud3ec \uc720\ud615 \uc9c0\ub3c4\ub97c \uc81c\uacf5\ud55c\ub2e4. \ub2e4\ub9cc \uae30\uc220\uc801 \ud3b8\ud5a5\uacfc \ud574\uc11d\uc0c1\uc758 \ud55c\uacc4\ub294 \uc5f0\uad6c\ub9c8\ub2e4 \ub2e4\ub974\ubbc0\ub85c \uad50\ucc28 \uac80\uc99d\uc774 \ud544\uc218\uc801\uc774\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<p><strong>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/strong><\/p>\n<ul>\n<li>\uc0dd\uc950 \uacb0\uacfc\ub97c \uc778\uac04 \uc5f0\ub839\u00b7\uc9c8\ubcd1\uc73c\ub85c \uc9c1\uc811 \ub300\uc751\ud560 \uc218 \uc788\ub294\uc9c0 \uc5ec\ubd80\ub294 \ucd94\uac00 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4.<\/li>\n<li>\uc7a5\uae30 \uac04 \ub3d9\uae30\ud654\ub97c \uc77c\uc73c\ud0a4\ub294 \uad6c\uccb4\uc801 \ub9e4\uac1c\uccb4(\ud2b9\uc815 \uc0ac\uc774\ud1a0\uce74\uc778\u00b7\ub300\uc0ac\ubb3c\uc9c8)\uc758 \uc778\uacfc\uad00\uacc4\ub294 \uc544\uc9c1 \ud655\uc815\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc0ac\uc774\ud1a0\uce74\uc778 \uc870\uc808 \uc57d\ubb3c\uc774 \uc804\uc2e0\uc801 \ub178\ud654\ub97c \uc9c0\uc5f0\uc2dc\ud0ac \uc218 \uc788\ub2e4\ub294 \uac00\ub2a5\uc131\uc740 \uc81c\uae30\ub418\uc5c8\uc73c\ub098 \uc784\uc0c1\uc801 \ud6a8\ub2a5\uacfc \uc548\uc804\uc131\uc740 \ubbf8\ud655\uc778\uc774\ub2e4.<\/li>\n<li>\uc138\ud3ec \uc544\ud615 \uc7ac\ud3b8\uc758 \uc7a5\uae30\uc801 \uae30\ub2a5\uc801 \uc601\ud5a5(\uc608: \uc870\uc9c1 \uc7ac\uc0dd\ub825 \uc800\ud558 \ub610\ub294 \uc9c8\ud658 \ubbfc\uac10\ub3c4 \uc99d\ub300)\uc740 \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.<\/li>\n<\/ul>\n<p><strong>\ucd1d\ud3c9<\/strong><\/p>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ub178\ud654\uac00 \ud2b9\uc815 \uc2dc\uc810\uc5d0 \uac11\uc790\uae30 \ubc1c\uc0dd\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \ubc1c\ub2ec\uacfc \uc5f0\uc18d\ub41c \ub2e8\uacc4\ub85c\uc11c \uc77c\ucc0d\ubd80\ud130 \uc2dc\uc791\ub418\uace0, \uc7a5\uae30 \uac04\uc5d0 \ub3d9\uae30\ud654\ub41c \ubcc0\ud654\uac00 \uc874\uc7ac\ud560 \uc218 \uc788\uc74c\uc744 \uc81c\uc2dc\ud588\ub2e4. \ub2e8\uc77c\uc138\ud3ec \uc218\uc900\uc758 \ub300\uaddc\ubaa8 \uc9c0\ub3c4\ub294 \ub178\ud654 \uba54\ucee4\ub2c8\uc998 \uc5f0\uad6c\uc640 \ud45c\uc801 \uce58\ub8cc \uac1c\ubc1c\uc758 \uadc0\uc911\ud55c \uc790\uc6d0\uc774 \ub418\uba70, \uacf5\uac1c \ub370\uc774\ud130\ub294 \ud559\uacc4\uc758 \ucd94\uac00 \ubd84\uc11d\uc744 \ucd09\uc9c4\ud560 \uac83\uc774\ub2e4. \uadf8\ub7ec\ub098 \ub3d9\ubb3c \ubaa8\ub378\uc758 \ud55c\uacc4\uc640 \uc778\uacfc\uad00\uacc4 \ubbf8\ud655\uc815\uc131\uc740 \uc5ec\uc804\ud788 \uc8fc\uc694 \uc81c\uc57d\uc73c\ub85c \ub0a8\uc544 \uc788\uc73c\uba70, \uc778\uac04 \ub300\uc0c1 \uad50\ucc28 \uac80\uc99d\uacfc \uc784\uc0c1\uc801 \uc5f0\uacb0 \uace0\ub9ac \ud655\ubcf4\uac00 \ub2e4\uc74c \ub2e8\uacc4 \uacfc\uc81c\ub85c \ub0a8\uc544 \uc788\ub2e4.<\/p>\n<p><strong>\ucd9c\ucc98<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/kormedi.com\/2794201\/\" target=\"_blank\" rel=\"noopener\">\ucf54\uba54\ub514\ub2f7\ucef4 \ubcf4\ub3c4<\/a> (\uc5b8\ub860 \ubcf4\ub3c4)<\/li>\n<li><a href=\"https:\/\/www.science.org\" target=\"_blank\" rel=\"noopener\">\uc0ac\uc774\uc5b8\uc2a4(Science) \uac8c\uc7ac \ub17c\ubb38<\/a> (\ud559\uc220\uc9c0)<\/li>\n<li><a href=\"https:\/\/epiage.net\" target=\"_blank\" rel=\"noopener\">epiage.net<\/a> (\uc5f0\uad6c \uacf5\uac1c \ud50c\ub7ab\ud3fc, \uacf5\uc2dd \ub370\uc774\ud130)<\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \ubbf8\uad6d \ub85d\ud3a0\ub7ec\ub300 \uc8fc\ub2c8\uc6e8 \ucc28\uc624 \uad50\uc218\ud300\uc774 \ud559\uc220\uc9c0 \uc0ac\uc774\uc5b8\uc2a4\uc5d0 21\uac1c \uc7a5\uae30\uc5d0\uc11c \uc57d 700\ub9cc \uac1c \uc138\ud3ec\ub97c \ub2e8\uc77c\uc138\ud3ec \uc218\uc900\uc73c\ub85c \ubd84\uc11d\ud55c \uacb0\uacfc\ub97c \ubcf4\uace0\ud588\ub2e4. \uc5f0\uad6c\ub294 \uc0dd\ud6c4 1\uac1c\uc6d4\u00b75\uac1c\uc6d4\u00b721\uac1c\uc6d4\uc758 \uc0dd\uc950 32\ub9c8\ub9ac\ub97c \ub300\uc0c1\uc73c\ub85c \uc9c4\ud589\ub410\uc73c\uba70, \ub178\ud654 \uc2e0\ud638\uac00 \uc608\uc0c1\ubcf4\ub2e4 \uc774\ub974\uac8c \uc2dc\uc791\ub418\uace0 \uc5ec\ub7ec \uc7a5\uae30\uc5d0\uc11c \ub3d9\uae30\ud654\ub41c \ubc29\uc2dd\uc73c\ub85c \uc9c4\ud589\ub41c\ub2e4\ub294 \uacb0\ub860\uc744 \uc81c\uc2dc\ud55c\ub2e4. \ub610\ud55c \uc138\ud3ec \uc720\ud615 \uad6c\uc131 \uc790\uccb4\uac00 \uc7ac\ud3b8\ub418\ub294 \ud604\uc0c1\uacfc \uc131\ubcc4\uc5d0 \ub530\ub978 \ucc28\uc774\ub97c \ud655\uc778\ud588\ub2e4. \uc5f0\uad6c \uacb0\uacfc\uc640 \ub370\uc774\ud130\ub294 \uacf5\uac1c \ud50c\ub7ab\ud3fc\uc744 &#8230; <a title=\"\uc6b0\ub9ac \ubab8\uc740 \uc5b4\ub5bb\uac8c \ub299\ub098: 21\uac1c \uc7a5\uae30\u00b7700\ub9cc \uc138\ud3ec \ub2e8\uc77c\uc138\ud3ec \uc544\ud2c0\ub77c\uc2a4 \uacf5\uac1c\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/single-cell-aging-atlas\/\" aria-label=\"\uc6b0\ub9ac \ubab8\uc740 \uc5b4\ub5bb\uac8c \ub299\ub098: 21\uac1c \uc7a5\uae30\u00b7700\ub9cc \uc138\ud3ec \ub2e8\uc77c\uc138\ud3ec \uc544\ud2c0\ub77c\uc2a4 \uacf5\uac1c\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":9465,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\uc6b0\ub9ac \ubab8\uc740 \uc5b4\ub5bb\uac8c \ub299\ub098: 21\uac1c \uc7a5\uae30\u00b7700\ub9cc \uc138\ud3ec \uc544\ud2c0\ub77c\uc2a4 \uacf5\uac1c - \ud5ec\uc2a4\uc778\uc0ac\uc774\ud2b8","rank_math_description":"\ub85d\ud3a0\ub7ec\ub300 \uc5f0\uad6c\uc9c4\uc774 21\uac1c \uc7a5\uae30 \uc57d 700\ub9cc \uc138\ud3ec\ub97c \ub2e8\uc77c\uc138\ud3ec \uc218\uc900\uc73c\ub85c \ubd84\uc11d\ud574 \ub178\ud654\uac00 \uc911\ub144\ubd80\ud130 \uc2dc\uc791\ub418\uace0 \uc7a5\uae30 \uac04 \ub3d9\uae30\ud654\ub41c \ud328\ud134\uc744 \ubcf4\uc778\ub2e4\ub294 \uacb0\uacfc\ub97c \uacf5\uac1c\ud588\ub2e4. \ub370\uc774\ud130\ub294 \uacf5\uac1c \ud50c\ub7ab\ud3fc\uc5d0\uc11c \ud655\uc778\ud560 \uc218 \uc788\ub2e4.","rank_math_focus_keyword":"\ub178\ud654,\ub2e8\uc77c\uc138\ud3ec,\uc544\ud2c0\ub77c\uc2a4,ATAC-seq,\uba74\uc5ed","footnotes":""},"categories":[2],"tags":[],"class_list":["post-9469","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=9469"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9469\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/9465"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=9469"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=9469"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=9469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}