{"id":9638,"date":"2026-03-06T12:07:13","date_gmt":"2026-03-06T03:07:13","guid":{"rendered":"https:\/\/readtrends.com\/ko\/pembrolizumab-nivolumab-gastric\/"},"modified":"2026-03-06T12:07:13","modified_gmt":"2026-03-06T03:07:13","slug":"pembrolizumab-nivolumab-gastric","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/pembrolizumab-nivolumab-gastric\/","title":{"rendered":"\ud0a4\ud2b8\ub8e8\ub2e4\u00b7\uc635\ub514\ubcf4 \uc704\uc554 1\ucc28 \uce58\ub8cc \uae09\uc5ec \ud655\ub300 &#8216;\uccad\uc2e0\ud638&#8217; &#8211; \uc758\ud611\uc2e0\ubb38"},"content":{"rendered":"<article>\n<h2>\ud575\uc2ec \uc694\uc57d<\/h2>\n<p>\uac74\uac15\ubcf4\ud5d8\uc2ec\uc0ac\ud3c9\uac00\uc6d0(\uc2ec\ud3c9\uc6d0) \uc57d\uc81c\uae09\uc5ec\ud3c9\uac00\uc704\uc6d0\ud68c\ub294 5\uc77c \uba74\uc5ed\ud56d\uc554\uc81c \ud0a4\ud2b8\ub8e8\ub2e4(\ud3a8\ube0c\ub864\ub9ac\uc8fc\ub9d9)\uc640 \uc635\ub514\ubcf4(\ub2c8\ubcfc\ub8e8\ub9d9)\uc5d0 \ub300\ud574 \uc704\uc554 1\ucc28 \uce58\ub8cc\uc81c \uae09\uc5ec\ubc94\uc704 \ud655\ub300\uc758 \uc801\uc815\uc131\uc774 \uc788\ub2e4\ub294 \uacb0\ub860\uc744 \ub0b4\ub838\ub2e4. \uae09\uc5ec \ud655\ub300 \ub300\uc0c1\uc740 \uc218\uc220 \ubd88\uac00\ub2a5\ud558\uac70\ub098 \uc9c4\ud589\uc131\u00b7\uc804\uc774\uc131 \uc704\uc120\uc554 \ubc0f \uc704\uc2dd\ub3c4 \uc811\ud569\ubd80 \uc120\uc554 \uc911 dMMR \ub610\ub294 MSI-H \uc591\uc131(\ub2e8, HER2 \uc591\uc131 \uc81c\uc678) \ud658\uc790\ub2e4. \uac19\uc740 \ud68c\uc758\uc5d0\uc11c \ub274\ubca0\uce74, \ube0c\ub9ac\ubca0\ud0c0, \uc2dc\uc2a4\ud3f4 \ub4f1\uc740 \uc81c\uc57d\uc0ac\uac00 \ud3c9\uac00\uae08\uc561 \uc774\ud558\ub85c \uc218\uc6a9\ud560 \uacbd\uc6b0 \uc870\uac74\ubd80 \uae09\uc5ec\ub97c \uc778\uc815\ud558\ub294 \uacb0\uc815\uc744 \ubc1b\uc558\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc2ec\ud3c9\uc6d0 \uc57d\uc81c\uae09\uc5ec\ud3c9\uac00\uc704\uc6d0\ud68c\ub294 5\uc77c \ud68c\uc758\ub97c \uc5f4\uace0 \ud0a4\ud2b8\ub8e8\ub2e4\uc640 \uc635\ub514\ubcf4\uc758 \uc704\uc554 1\ucc28 \uce58\ub8cc \uae09\uc5ec\ud655\ub300 \uc801\uc815\uc131\uc774 \uc788\ub2e4\uace0 \ud310\ub2e8\ud588\ub2e4.<\/li>\n<li>\uae09\uc5ec\ud655\ub300 \ubc94\uc704\ub294 \ubd88\uc77c\uce58 \ubcf5\uad6c \uacb0\ud568(dMMR) \ub610\ub294 \uace0\ube48\ub3c4 \ud604\ubbf8\ubd80\uc218\uccb4 \ubd88\uc548\uc815\uc131(MSI-H)\uc744 \ubcf4\uc774\ub294 \uc218\uc220 \ubd88\uac00\ub2a5\u00b7\uc9c4\ud589\uc131\u00b7\uc804\uc774\uc131 \uc704\uc120\uc554 \ubc0f \uc704\uc2dd\ub3c4 \uc811\ud569\ubd80 \uc120\uc554\uc774\uba70, HER2 \uc591\uc131 \ud658\uc790\ub294 \uc81c\uc678\ub41c\ub2e4.<\/li>\n<li>\ub274\ubca0\uce74(\ub2e4\ub85c\ub8e8\ud0c0\ub9c8\uc774\ub4dc), \ube0c\ub9ac\ubca0\ud0c0(\ube0c\ub9ac\ubc14\ub77c\uc138\ud0d0), \uc2dc\uc2a4\ud3f4\uc5d0 \ub300\ud574\uc11c\ub294 \uc81c\uc57d\uc0ac\uac00 \ud3c9\uac00\uae08\uc561 \uc774\ud558\ub85c \uc218\uc6a9\ud560 \uacbd\uc6b0 \uae09\uc5ec \uc801\uc815\uc131\uc744 \uc778\uc815\ud558\ub294 \uc870\uac74\ubd80 \uacb0\uc815\uc744 \ub0b4\ub838\ub2e4.<\/li>\n<li>\ub274\ubca0\uce74\uc758 \uc2e0\uccad \uc801\uc751\uc99d\uc740 nmCRPC(\uace0\uc704\ud5d8 \ube44\uc804\uc774\uc131 \uac70\uc138\uc800\ud56d\uc131 \uc804\ub9bd\uc120\uc554)\uc640 mHSPC(\ud638\ub974\ubaac \ubc18\uc751\uc131 \uc804\uc774\uc131 \uc804\ub9bd\uc120\uc554) \uad00\ub828 \ubcd1\uc6a9 \uc694\ubc95 \ub4f1\uc774\ub2e4.<\/li>\n<li>\ube0c\ub9ac\ubca0\ud0c0\ub294 16\uc138 \uc774\uc0c1 \ub1cc\uc804\uc99d \ud658\uc790\uc758 \ubd80\ubd84 \ubc1c\uc791 \ubcf4\uc870\uc694\ubc95\uc73c\ub85c \uc2e0\uccad\ub410\uace0, \uc2dc\uc2a4\ud3f4\uc740 \uc77c\uc2dc\uc801 \uc548\uad6c \ubd88\ud3b8\uac10 \uc644\ud654 \uc6a9\ub3c4\ub85c \uae09\uc5ec \uc801\uc815\uc131\uc744 \uc2ec\uc758\ud588\ub2e4.<\/li>\n<li>\uc57d\ud3c9\uc704\uc758 \uc774\ubc88 \ud310\ub2e8\uc740 \ucd5c\uc885 \uae09\uc5ec \ub4f1\uc7ac\ub97c \uc704\ud55c \uc801\uc815\uc131 \ud3c9\uac00 \uacb0\uacfc\uc774\uba70, \uc2e4\uc81c \uae09\uc5ec \uc801\uc6a9\uc740 \uac00\uaca9 \ud611\uc0c1\uacfc \ud589\uc815 \uc808\ucc28\ub97c \uac70\uccd0 \uacb0\uc815\ub41c\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>PD-1 \uacc4\uc5f4 \ud56d\uc554\uc81c\uc778 \ud3a8\ube0c\ub864\ub9ac\uc8fc\ub9d9\uacfc \ub2c8\ubcfc\ub8e8\ub9d9\uc740 \uc5ec\ub7ec \uace0\ud615\uc554\uc5d0\uc11c \uba74\uc5ed\uce58\ub8cc\uc758 \ud45c\uc900\uc694\ubc95\uc73c\ub85c \uc790\ub9ac\uc7a1\uc544 \uc654\ub2e4. \ud2b9\ud788 dMMR\u00b7MSI-H \ud45c\uc9c0\uc790\ub294 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \ubc18\uc751\ub960\uc774 \ub192\uc740 \ud558\uc704\uad70\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc5b4, \uc774 \ud45c\uc9c0\uc790\ub97c \uac00\uc9c4 \uc704\uc554 \ud658\uc790\uc5d0\uc11c \ud56d\uc554\uc81c\uc758 \ud6a8\uacfc\uac00 \uc8fc\ubaa9\ubc1b\uc544 \uc654\ub2e4. \uad6d\ub0b4\uc5d0\uc11c\ub294 \ube44\uc6a9 \ud6a8\uacfc\uc131\uacfc \uc7ac\uc815 \uc601\ud5a5\uc5d0 \ub300\ud55c \uc2ec\uc0ac\uac00 \uc5c4\uaca9\ud558\uac8c \uc801\uc6a9\ub418\uba70, \uc57d\ud3c9\uc704\ub294 \uc774\ub7ec\ud55c \uc784\uc0c1\uc801 \uc720\ud6a8\uc131\ubfd0 \uc544\ub2c8\ub77c \uc804\uccb4 \uc758\ub8cc\uc7ac\uc815\uc5d0 \ubbf8\uce60 \uc601\ud5a5\uae4c\uc9c0 \uace0\ub824\ud574 \uc801\uc815\uc131\uc744 \uc2ec\uc758\ud55c\ub2e4.<\/p>\n<p>\uc57d\uc81c \uae09\uc5ec\ud654 \uacfc\uc815\uc740 \uc801\uc815\uc131 \ud3c9\uac00, \uac00\uaca9\ud611\uc0c1, \uae09\uc5ec \uacb0\uc815\uc73c\ub85c \uc774\uc5b4\uc9c4\ub2e4. \uc774\ubc88 \uc57d\ud3c9\uc704\uc758 \uc801\uc815\uc131 \ud310\ub2e8\uc740 \uadf8 \uccab \ub2e8\uacc4\uc778 \ud3c9\uac00\ub97c \ud1b5\uacfc\ud55c \uc758\ubbf8\ub97c \uac00\uc9c0\uba70, \uc774\ud6c4 \uc81c\uc57d\uc0ac\uc640\uc758 \uc57d\uac00 \ud611\uc0c1\uc5d0\uc11c \uac00\uaca9\u00b7\uc801\uc751\uc99d \ubc94\uc704\uac00 \ucd5c\uc885\uc801\uc73c\ub85c \ud655\uc815\ub41c\ub2e4. \ub3d9\uc2dc\uc5d0 \uc758\ub8cc\ud604\uc7a5\uc5d0\uc11c\ub294 \uc720\uc804\uc790 \uac80\uc0ac(MSI\/dMMR) \uc2dc\ud589 \ud655\ub300 \ubc0f \ud658\uc790 \uc120\ubcc4 \uae30\uc900\uc758 \ud45c\uc900\ud654\uac00 \ud544\uc694\ud574\uc9c8 \uc804\ub9dd\uc774\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74 \uc804\uac1c<\/h2>\n<p>\uc2ec\ud3c9\uc6d0\uc740 5\uc77c \uac1c\ucd5c\ud55c \uc57d\ud3c9\uc704\uc5d0\uc11c \uad00\ub828 \uc790\ub8cc\uc640 \uc784\uc0c1 \uadfc\uac70\ub97c \uac80\ud1a0\ud55c \ub4a4 \ub450 \uc57d\uc81c\uc5d0 \ub300\ud574 \uae09\uc5ec\ud655\ub300 \uc801\uc815\uc131 \uc758\uacac\uc744 \ubaa8\uc558\ub2e4. \uc704\uc554 1\ucc28 \uce58\ub8cc\uc5d0\uc11c \ub450 \uc57d\uc81c\uc758 \uc0ac\uc6a9\uc744 \ud5c8\uc6a9\ud560 \uacbd\uc6b0 \ub300\uc0c1 \ud658\uc790\ub294 dMMR \ub610\ub294 MSI-H \uc591\uc131\uc790 \uc911\uc2ec\uc73c\ub85c \ud55c\uc815\ub410\ub2e4. \uc704\uc6d0\ud68c\ub294 HER2 \uc591\uc131 \ud658\uc790\ub294 \uc81c\uc678\ud558\ub294 \ub4f1 \uce58\ub8cc \ub300\uc0c1 \ubc94\uc704\ub97c \uad6c\uccb4\ud654\ud588\ub2e4.<\/p>\n<p>\ub3d9\uc77c \ud68c\uc758\uc5d0\uc11c \ub274\ubca0\uce74, \ube0c\ub9ac\ubca0\ud0c0, \uc2dc\uc2a4\ud3f4\uc5d0 \ub300\ud574\uc120 \uc81c\uc57d\uc0ac\uac00 \uc81c\uc2dc\ud55c \ud3c9\uac00\uae08\uc561\uc744 \uc218\uc6a9\ud558\uc9c0 \uc54a\uc744 \uacbd\uc6b0 \uae09\uc5ec\ub97c \uc778\uc815\ud558\uae30 \uc5b4\ub835\ub2e4\ub294 \ud310\ub2e8\uc744 \ud588\uc73c\ub098, \uc81c\uc57d\uc0ac\uac00 \ud3c9\uac00\uae08\uc561 \uc774\ud558\ub85c \uac00\uaca9\uc744 \uc870\uc815\ud558\uba74 \uc870\uac74\ubd80\ub85c \uae09\uc5ec \uc801\uc815\uc131\uc744 \uc778\uc815\ud558\uae30\ub85c \ud588\ub2e4. \uc774 \uacb0\uc815\uc740 \ud5a5\ud6c4 \uc57d\uac00\ud611\uc0c1\uc5d0\uc11c \uc81c\uc57d\uc0ac\uc5d0 \uac00\uaca9\uc870\uc815 \uc555\ub825\uc744 \uac00\ud558\ub294 \uc2e0\ud638\ub85c \ud574\uc11d\ub41c\ub2e4.<\/p>\n<p>\uc2ec\ud3c9\uc6d0\uc758 \uc801\uc815\uc131 \ud310\ub2e8 \ubc1c\ud45c \uc774\ud6c4 \ubcd1\uc6d0\uacfc \uc784\uc0c1\ud604\uc7a5\uc5d0\uc11c\ub294 \ub300\uc0c1 \ud658\uc790 \uc120\ubcc4\uc744 \uc704\ud55c MSI\/dMMR \uac80\uc0ac \uc218\uc694\uac00 \uc99d\uac00\ud560 \uac00\ub2a5\uc131\uc774 \uc81c\uae30\ub410\ub2e4. \ub3d9\uc2dc\uc5d0 \ud658\uc790\ub2e8\uccb4\uc640 \uc758\ub8cc\uacc4\ub294 \uc2e4\uc81c \uae09\uc5ec \uc801\uc6a9 \uc2dc\uc810\uacfc \ubcf8\uc778\ubd80\ub2f4\ub960 \ub4f1\uc5d0 \ucd09\uac01\uc744 \uace4\ub450\uc138\uc6b0\uace0 \uc788\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uc774\ubc88 \uc801\uc815\uc131 \ud310\ub2e8\uc740 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uac00 \uc704\uc554 1\ucc28 \uce58\ub8cc\uc758 \uc120\ud0dd\uc9c0\ub85c \uacf5\uc2dd\uc801\uc73c\ub85c \uac80\ud1a0\ub418\ub294 \uc804\ud658\uc810\uc774 \ub420 \uc218 \uc788\ub2e4. dMMR\u00b7MSI-H\ub294 \uc804\uccb4 \uc704\uc554 \ud658\uc790 \uc911 \ube44\uc728\uc774 \ud06c\uc9c0 \uc54a\uc9c0\ub9cc(\uc77c\ubc18\uc801\uc73c\ub85c \uc18c\uc218 \uc9d1\ub2e8), \uc774\ub4e4\uc5d0\uac90 \ud56d\uc554\uc81c\uc758 \uce58\ub8cc\ud6a8\uacfc\uac00 \ube44\uad50\uc801 \ub192\uc544 \ud658\uc790\uc784\uc0c1 \uacb0\uacfc \uac1c\uc120\uc5d0 \uae30\uc5ec\ud560 \uac00\ub2a5\uc131\uc774 \ud06c\ub2e4. \ub530\ub77c\uc11c \ud45c\uc801\ud654\ub41c \uae09\uc5ec \ud655\ub300\ub294 \uc81c\ud55c\ub41c \uc608\uc0b0\uc73c\ub85c\ub3c4 \ud6a8\uacfc\ub97c \uadf9\ub300\ud654\ud560 \uc218 \uc788\ub294 \uc815\ucc45\uc801 \uc120\ud0dd\uc774\ub2e4.<\/p>\n<p>\uacbd\uc81c\uc801 \uad00\uc810\uc5d0\uc11c\ub294 \ub450 \uac00\uc9c0 \ubcc0\uc218\uac00 \ud575\uc2ec\uc774\ub2e4. \ud558\ub098\ub294 \uc57d\uac00 \ud611\uc0c1 \uacb0\uacfc\ub85c, \uc57d\ud3c9\uc704\uc758 \uc870\uac74\ubd80 \uacb0\uc815\uc740 \uc81c\uc57d\uc0ac\uc5d0\uac8c \uac00\uaca9\uc778\ud558\ub97c \ucd09\uad6c\ud558\ub294 \uadfc\uac70\uac00 \ub41c\ub2e4. \ub2e4\ub978 \ud558\ub098\ub294 \ub300\uc0c1 \ud658\uc790 \uaddc\ubaa8\uc778\ub370, MSI-H\u00b7dMMR \uac80\uc0ac\uc728\uacfc \uc591\uc131\ub960\uc5d0 \ub530\ub77c \uc608\uce21 \uc7ac\uc815\uc601\ud5a5\uc774 \ub2ec\ub77c\uc9c4\ub2e4. \ub530\ub77c\uc11c \uc7ac\uc815 \uc608\uce21 \ubaa8\ub378\uacfc \uc2e4\uc81c \uc801\uc6a9 \ud6c4 \uc2e4\uc0ac\uc6a9 \ub370\uc774\ud130(RWE)\uac00 \uc911\uc694\ud55c \ud3c9\uac00\uadfc\uac70\uac00 \ub420 \uac83\uc774\ub2e4.<\/p>\n<p>\uad6d\uc81c\uc801 \ub9e5\ub77d\uc5d0\uc11c \ubcf4\uba74, \uc8fc\uc694 \uad6d\uac00\ub4e4\uc740 \uc774\ubbf8 PD-1 \uc5b5\uc81c\uc81c\ub97c \ud2b9\uc815 \ubc14\uc774\uc624\ub9c8\ucee4 \uae30\ubc18\uc73c\ub85c \uc704\uc554 \uce58\ub8cc\uc5d0 \ub3c4\uc785\ud574 \uc654\ub2e4. \ud55c\uad6d\uc758 \uc57d\ud3c9\uc704 \uacb0\uc815\uc740 \uad6d\uc81c\uc801 \ud750\ub984\uacfc \ub300\uccb4\ub85c \uc77c\uce58\ud558\uc9c0\ub9cc, \uad6d\ub0b4 \ubcf4\ud5d8\uccb4\uacc4\uc640 \uc7ac\uc815\uc5ec\uac74\uc5d0 \ub9de\ucd98 \uc801\uc751\uc99d\u00b7\uc81c\ud55c \uaddc\uc815\uc744 \ub450\uc5c8\ub2e4\ub294 \uc810\uc774 \ud2b9\uc9d5\uc774\ub2e4. \uacb0\uacfc\uc801\uc73c\ub85c \ud658\uc790 \uc811\uadfc\uc131\uc740 \uac1c\uc120\ub418\uaca0\uc73c\ub098, \uc81c\ub3c4\uc801 \uc900\ube44\uc640 \ubaa8\ub2c8\ud130\ub9c1\uc774 \ubcd1\ud589\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\uc9c8\ud658\/\uc57d\uc81c<\/th>\n<th>\uc704\uc6d0\ud68c \ud310\ub2e8<\/th>\n<th>\uc8fc\uc694 \uc801\uc6a9 \ubc94\uc704<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\ud0a4\ud2b8\ub8e8\ub2e4(\ud3a8\ube0c\ub864\ub9ac\uc8fc\ub9d9)<\/td>\n<td>\uae09\uc5ec\ud655\ub300 \uc801\uc815\uc131 \uc788\uc74c<\/td>\n<td>dMMR \ub610\ub294 MSI-H, \uc218\uc220\ubd88\uac00\u00b7\uc9c4\ud589\uc131\u00b7\uc804\uc774\uc131 \uc704\uc120\uc554\u00b7\uc704\uc2dd\ub3c4 \uc811\ud569\ubd80 \uc120\uc554 (HER2 \uc81c\uc678)<\/td>\n<\/tr>\n<tr>\n<td>\uc635\ub514\ubcf4(\ub2c8\ubcfc\ub8e8\ub9d9)<\/td>\n<td>\uae09\uc5ec\ud655\ub300 \uc801\uc815\uc131 \uc788\uc74c<\/td>\n<td>\ub3d9\uc77c \uae30\uc900<\/td>\n<\/tr>\n<tr>\n<td>\ub274\ubca0\uce74(\ub2e4\ub85c\ub8e8\ud0c0\ub9c8\uc774\ub4dc)<\/td>\n<td>\uc870\uac74\ubd80 \uae09\uc5ec(\ud3c9\uac00\uae08\uc561 \uc774\ud558 \uc218\uc6a9 \uc2dc)<\/td>\n<td>nmCRPC, mHSPC \ubcd1\uc6a9 \uc694\ubc95 \uc2e0\uccad<\/td>\n<\/tr>\n<tr>\n<td>\ube0c\ub9ac\ubca0\ud0c0(\ube0c\ub9ac\ubc14\ub77c\uc138\ud0d0)<\/td>\n<td>\uc870\uac74\ubd80 \uae09\uc5ec(\ud3c9\uac00\uae08\uc561 \uc774\ud558 \uc218\uc6a9 \uc2dc)<\/td>\n<td>16\uc138 \uc774\uc0c1 \ubd80\ubd84 \ubc1c\uc791 \ubcf4\uc870\uc694\ubc95<\/td>\n<\/tr>\n<tr>\n<td>\uc2dc\uc2a4\ud3f4(\uc720\ub2c8\uba54\ub4dc)<\/td>\n<td>\uc870\uac74\ubd80 \uae09\uc5ec(\ud3c9\uac00\uae08\uc561 \uc774\ud558 \uc218\uc6a9 \uc2dc)<\/td>\n<td>\uc548\uad6c \ubd88\ud3b8\uac10 \uc77c\uc2dc \uc644\ud654<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \uc57d\ud3c9\uc704\uc758 \uc801\uc815\uc131 \ud310\ub2e8\uacfc \uc2e0\uccad\ub41c \uc801\uc751\uc99d\uc744 \uc815\ub9ac\ud55c \uac83\uc774\ub2e4. \uc2e4\uc81c \uae09\uc5ec \ub4f1\uc7ac \uc5ec\ubd80\uc640 \uc801\uc6a9 \uc2dc\uc810\uc740 \uc774\ud6c4 \uc57d\uac00\ud611\uc0c1\uacfc \ud589\uc815\uc2ec\uc0ac \uacb0\uacfc\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9c4\ub2e4. \ub610\ud55c \ub300\uc0c1 \ud658\uc790 \uaddc\ubaa8\ub294 MSI\/dMMR \uac80\uc0ac \ubcf4\uae09\ub960\uacfc \uc591\uc131\ub960\uc5d0 \ub530\ub77c \ubcc0\ub3d9\ub420 \uc218 \uc788\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<blockquote>\n<p>&#8220;\uc704\uc6d0\ud68c\ub294 \ub450 \uc57d\uc81c\uc758 \uc704\uc554 1\ucc28 \uce58\ub8cc\uc5d0 \ub300\ud55c \uae09\uc5ec\ubc94\uc704 \ud655\ub300\uac00 \uc801\uc815\ud558\ub2e4\uace0 \ud310\ub2e8\ud588\ub2e4.&#8221;<\/p>\n<p><cite>\uac74\uac15\ubcf4\ud5d8\uc2ec\uc0ac\ud3c9\uac00\uc6d0(\uacf5\uc2dd \ubc1c\ud45c)<\/cite><\/p><\/blockquote>\n<blockquote>\n<p>&#8220;\uc81c\uc57d\uc0ac\uac00 \ud3c9\uac00\uae08\uc561 \uc774\ud558\ub85c \uc218\uc6a9\ud560 \uacbd\uc6b0 \ub274\ubca0\uce74 \ub4f1 \uc77c\ubd80 \uc57d\uc81c\uc5d0 \ub300\ud574 \uc870\uac74\ubd80 \uae09\uc5ec \uc778\uc815\uc774 \uac00\ub2a5\ud558\ub2e4\ub294 \uacb0\uc815\uc744 \ub0b4\ub838\ub2e4.&#8221;<\/p>\n<p><cite>\uc2ec\ud3c9\uc6d0 \uc57d\uc81c\uae09\uc5ec\ud3c9\uac00\uc704\uc6d0\ud68c(\uacf5\uc2dd)<\/cite><\/p><\/blockquote>\n<blockquote>\n<p>&#8220;\uc774\ubc88 \uacb0\uc815\uc740 MSI-H\u00b7dMMR \uc591\uc131 \ud658\uc790\uc758 \uce58\ub8cc \uc120\ud0dd\uc9c0\ub97c \ub113\ud790 \uc218 \uc788\ub294 \uc804\ud5a5\uc801 \uc2e0\ud638\uc9c0\ub9cc, \uc2e4\uc81c \uc801\uc6a9 \uc2dc\uae30\uc640 \uc57d\uac00\ud611\uc0c1 \uacb0\uacfc\ub97c \uc9c0\ucf1c\ubd10\uc57c \ud55c\ub2e4.&#8221;<\/p>\n<p><cite>\uc758\ub8cc\uacc4\u00b7\uc804\ubb38\uac00 \ubc18\uc751(\uc885\ud569)<\/cite><\/p><\/blockquote>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>dMMR(\ubd88\uc77c\uce58 \ubcf5\uad6c \uacb0\ud568)\uacfc MSI-H(\uace0\ube48\ub3c4 \ud604\ubbf8\ubd80\uc218\uccb4 \ubd88\uc548\uc815\uc131)\ub294 \uc554\uc138\ud3ec\uc758 \uc720\uc804\uccb4 \ubd88\uc548\uc815\uc131\uc744 \ub098\ud0c0\ub0b4\ub294 \ubc14\uc774\uc624\ub9c8\ucee4\ub85c, \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \ubc18\uc751\uc131\uacfc \uc5f0\uad00\uc131\uc774 \ubcf4\uace0\ub3fc \uc654\ub2e4. \uc57d\uc81c\uae09\uc5ec\ud3c9\uac00\uc704\uc6d0\ud68c\ub294 \uc784\uc0c1 \uadfc\uac70\uc640 \ube44\uc6a9\ud6a8\uacfc\uc131, \uc758\ub8cc\uc7ac\uc815 \uc601\ud5a5 \ub4f1\uc744 \uc885\ud569\ud574 \uae09\uc5ec \uc801\uc815\uc131\uc744 \ud3c9\uac00\ud55c\ub2e4. \uc870\uac74\ubd80 \uae09\uc5ec\ub294 \uc784\uc0c1\uc801 \uc720\ud6a8\uc131\uc740 \uc778\uc815\ub418\ub098 \uc57d\uac00 \ub4f1 \uc7ac\uc815\uc801 \uc694\uc18c\uc5d0 \ub300\ud574 \ucd94\uac00 \ud611\uc758\uac00 \ud544\uc694\ud560 \ub54c \uc0ac\uc6a9\ub418\ub294 \uc81c\ub3c4\uc801 \uc218\ub2e8\uc774\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\uc2e4\uc81c \uae09\uc5ec \uc801\uc6a9 \uc2dc\uc810\uacfc \ubcf8\uc778\ubd80\ub2f4\ub960 \ub4f1 \uad6c\uccb4\uc801 \uae09\uc5ec \uae30\uc900\uc740 \uc544\uc9c1 \ud655\uc815\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc81c\uc57d\uc0ac\uc640\uc758 \uc57d\uac00 \ud611\uc0c1 \uacb0\uacfc(\ud3c9\uac00\uae08\uc561 \uc774\ud558 \uc218\uc6a9 \uc5ec\ubd80)\ub294 \ubbf8\ud655\uc778 \uc0c1\ud0dc\uc774\ub2e4.<\/li>\n<li>\uad6d\ub0b4 \ud604\uc2e4 \uc9c4\ub8cc \ud604\uc7a5\uc5d0\uc11c MSI-H\u00b7dMMR \uac80\uc0ac \ubcf4\uae09\ub960 \uc0c1\uc2b9 \uc5ec\ubd80\uc640 \uc591\uc131\ub960\uc5d0 \ub530\ub978 \uc608\uce21 \uc7ac\uc815\uc601\ud5a5\uc740 \ubd88\ud655\uc2e4\ud558\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc2ec\ud3c9\uc6d0\uc758 \uc774\ubc88 \uc801\uc815\uc131 \ud310\ub2e8\uc740 \ud0a4\ud2b8\ub8e8\ub2e4\uc640 \uc635\ub514\ubcf4\uac00 \uad6d\ub0b4 \uc704\uc554 \uce58\ub8cc\uc5d0\uc11c \ubc14\uc774\uc624\ub9c8\ucee4 \uae30\ubc18 1\ucc28 \uce58\ub8cc \uc635\uc158\uc73c\ub85c \uc790\ub9ac\uc7a1\uc744 \uac00\ub2a5\uc131\uc744 \uc5f4\uc5c8\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ubbf8\uac00 \ud06c\ub2e4. \ub2e4\ub9cc \uc774\ub294 \uc801\uc815\uc131 \ud3c9\uac00 \ub2e8\uacc4\uc758 \uacb0\ub860\uc73c\ub85c, \ucd5c\uc885 \uae09\uc5ec \ub4f1\uc7ac\ub97c \uc704\ud574\uc120 \uc57d\uac00\ud611\uc0c1\uacfc \ud589\uc815 \uc808\ucc28\uac00 \ub0a8\uc544 \uc788\ub2e4. \uc81c\uc57d\uc0ac \uce21\uc758 \uac00\uaca9 \uc218\uc6a9 \uc5ec\ubd80\uc640 \uc815\ubd80\uc758 \uc7ac\uc815 \ud310\ub2e8\uc774 \ucd5c\uc885 \ud5a5\ubc29\uc744 \uacb0\uc815\ud560 \uac83\uc774\ub2e4.<\/p>\n<p>\uc758\ub8cc\ud604\uc7a5\uc5d0\uc11c\ub294 MSI\/dMMR \uac80\uc0ac \uccb4\uacc4 \uc815\ube44\uc640 \ub300\uc0c1 \ud658\uc790 \uc120\ubcc4 \uc9c0\uce68 \ub9c8\ub828\uc774 \ubcd1\ud589\ub418\uc5b4\uc57c \ud658\uc790 \uc811\uadfc\uc131 \uac1c\uc120\uc774 \uc2e4\uc9c8\uc801 \uc131\uacfc\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub2e4. \ub3c5\uc790\ub294 \ud5a5\ud6c4 \uc57d\uac00\ud611\uc0c1 \uacb0\uacfc\uc640 \uc2ec\ud3c9\uc6d0\uc758 \ucd5c\uc885 \uace0\uc2dc\ub97c \uc8fc\ubaa9\ud574\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.doctorsnews.co.kr\/news\/articleView.html?idxno=163595\" target=\"_blank\" rel=\"noopener\">\uc758\ud611\uc2e0\ubb38(\uc5b8\ub860 \ubcf4\ub3c4)<\/a><\/li>\n<li><a href=\"https:\/\/www.hira.or.kr\/\" target=\"_blank\" rel=\"noopener\">\uac74\uac15\ubcf4\ud5d8\uc2ec\uc0ac\ud3c9\uac00\uc6d0(\uacf5\uc2dd \uae30\uad00)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \uac74\uac15\ubcf4\ud5d8\uc2ec\uc0ac\ud3c9\uac00\uc6d0(\uc2ec\ud3c9\uc6d0) \uc57d\uc81c\uae09\uc5ec\ud3c9\uac00\uc704\uc6d0\ud68c\ub294 5\uc77c \uba74\uc5ed\ud56d\uc554\uc81c \ud0a4\ud2b8\ub8e8\ub2e4(\ud3a8\ube0c\ub864\ub9ac\uc8fc\ub9d9)\uc640 \uc635\ub514\ubcf4(\ub2c8\ubcfc\ub8e8\ub9d9)\uc5d0 \ub300\ud574 \uc704\uc554 1\ucc28 \uce58\ub8cc\uc81c \uae09\uc5ec\ubc94\uc704 \ud655\ub300\uc758 \uc801\uc815\uc131\uc774 \uc788\ub2e4\ub294 \uacb0\ub860\uc744 \ub0b4\ub838\ub2e4. \uae09\uc5ec \ud655\ub300 \ub300\uc0c1\uc740 \uc218\uc220 \ubd88\uac00\ub2a5\ud558\uac70\ub098 \uc9c4\ud589\uc131\u00b7\uc804\uc774\uc131 \uc704\uc120\uc554 \ubc0f \uc704\uc2dd\ub3c4 \uc811\ud569\ubd80 \uc120\uc554 \uc911 dMMR \ub610\ub294 MSI-H \uc591\uc131(\ub2e8, HER2 \uc591\uc131 \uc81c\uc678) \ud658\uc790\ub2e4. \uac19\uc740 \ud68c\uc758\uc5d0\uc11c \ub274\ubca0\uce74, \ube0c\ub9ac\ubca0\ud0c0, \uc2dc\uc2a4\ud3f4 \ub4f1\uc740 \uc81c\uc57d\uc0ac\uac00 \ud3c9\uac00\uae08\uc561 \uc774\ud558\ub85c \uc218\uc6a9\ud560 \uacbd\uc6b0 \uc870\uac74\ubd80 \uae09\uc5ec\ub97c \uc778\uc815\ud558\ub294 \uacb0\uc815\uc744 \ubc1b\uc558\ub2e4. \ud575\uc2ec &#8230; <a title=\"\ud0a4\ud2b8\ub8e8\ub2e4\u00b7\uc635\ub514\ubcf4 \uc704\uc554 1\ucc28 \uce58\ub8cc \uae09\uc5ec \ud655\ub300 &#8216;\uccad\uc2e0\ud638&#8217; &#8211; \uc758\ud611\uc2e0\ubb38\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/pembrolizumab-nivolumab-gastric\/\" aria-label=\"\ud0a4\ud2b8\ub8e8\ub2e4\u00b7\uc635\ub514\ubcf4 \uc704\uc554 1\ucc28 \uce58\ub8cc \uae09\uc5ec \ud655\ub300 &#8216;\uccad\uc2e0\ud638&#8217; &#8211; \uc758\ud611\uc2e0\ubb38\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":9633,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\ud0a4\ud2b8\ub8e8\ub2e4\u00b7\uc635\ub514\ubcf4 \uc704\uc554 1\ucc28 \uce58\ub8cc \uae09\uc5ec \ud655\ub300 \ud310\ub2e8 \u2014 \uc758\ud611\uc2e0\ubb38","rank_math_description":"\uc2ec\ud3c9\uc6d0 \uc57d\uc81c\uae09\uc5ec\ud3c9\uac00\uc704\uc6d0\ud68c\uac00 5\uc77c \ud0a4\ud2b8\ub8e8\ub2e4\u00b7\uc635\ub514\ubcf4\uc758 \uc704\uc554 1\ucc28 \uce58\ub8cc \uae09\uc5ec\ud655\ub300 \uc801\uc815\uc131\uc744 \uc778\uc815\ud588\ub2e4. \ub300\uc0c1\uc740 dMMR\u00b7MSI-H \uc591\uc131\uc758 \uc218\uc220\ubd88\uac00\u00b7\uc9c4\ud589\uc131\u00b7\uc804\uc774\uc131 \uc704\uc120\uc554 \ub4f1\uc774\ub2e4.","rank_math_focus_keyword":"\ud0a4\ud2b8\ub8e8\ub2e4,\uc635\ub514\ubcf4,\uc704\uc554,MSI-H,dMMR,\uae09\uc5ec\ud655\ub300","footnotes":""},"categories":[2],"tags":[],"class_list":["post-9638","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9638","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=9638"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9638\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/9633"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=9638"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=9638"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=9638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}