{"id":9789,"date":"2026-03-09T09:07:31","date_gmt":"2026-03-09T00:07:31","guid":{"rendered":"https:\/\/readtrends.com\/ko\/drug-stroke-risk-meta-analysis\/"},"modified":"2026-03-09T09:07:31","modified_gmt":"2026-03-09T00:07:31","slug":"drug-stroke-risk-meta-analysis","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/drug-stroke-risk-meta-analysis\/","title":{"rendered":"\ub300\ub9c8\u00b7\ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c, \ub1cc\uc878\uc911 \uc704\ud5d8 \ud06c\uac8c \ub192\uc5ec"},"content":{"rendered":"<article>\n<h2>\ud575\uc2ec \uc694\uc57d<\/h2>\n<p>\ucd5c\uadfc \uad6d\uc81c \ud559\uc220\uc9c0\uc5d0 \uc2e4\ub9b0 \uccb4\uacc4\uc801 \ubb38\ud5cc\uace0\ucc30\u00b7\uba54\ud0c0\ubd84\uc11d\uacfc \uc720\uc804\uc790\ub3c4\uad6c \ubd84\uc11d(Mendelian randomization)\uc740 \ub300\ub9c8(\uce78\ub098\ube44\uc2a4), \ucf54\uce74\uc778, \uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c \uc0ac\uc6a9\uc790\uac00 \ube44\uc0ac\uc6a9\uc790\ubcf4\ub2e4 \ub1cc\uc878\uc911 \uc704\ud5d8\uc774 \uc720\uc758\ud558\uac8c \ub192\ub2e4\ub294 \uacb0\uacfc\ub97c \ubcf4\uace0\ud588\ub2e4. \uc5f0\uad6c\ub294 \uad00\ucc30\uc5f0\uad6c 32\uac74\uc744 \uc885\ud569\ud558\uace0 \uc720\uc804\ud559 \uae30\ubc18 \ubd84\uc11d\uc744 \ubcd1\ud589\ud574 \uc77c\ubd80 \uc57d\ubb3c\uacfc \ub1cc\uc878\uc911 \uc0ac\uc774\uc758 \uc778\uacfc\uad00\uacc4 \uac00\ub2a5\uc131\ub3c4 \uac80\ud1a0\ud588\ub2e4. \uad6d\ub0b4 \uc790\ub8cc\uc640 \uacb0\ud569\ud558\uba74 \ud2b9\uc815 \uc5f0\ub839\ub300\uc5d0\uc11c \uc57d\ubb3c \uc0ac\uc6a9\uc758 \uc720\ubcd1\ub960\uc774 \ub192\uc544 \uad00\ub828 \uacf5\uc911\ubcf4\uac74 \uc601\ud5a5\uc774 \ud074 \uac83\uc73c\ub85c \ucd94\uc815\ub41c\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c \uc720\ud615: Megan Ritson \ub4f1 \uc5f0\uad6c\uc9c4\uc758 \uccb4\uacc4\uc801 \ubb38\ud5cc\uace0\ucc30, \uba54\ud0c0\ubd84\uc11d \ubc0f Mendelian randomization(International Journal of Stroke)\uc774\ub2e4.<\/li>\n<li>\uc5f0\uad6c \ubc94\uc704: \uad00\ucc30\uc5f0\uad6c 32\uac74\uc774 \uba54\ud0c0\ubd84\uc11d\uc5d0 \ud3ec\ud568\ub418\uc5b4 \uc57d\ubb3c\ubcc4\u00b7\uc5f0\ub839\ubcc4 \uc704\ud5d8\ube44\ub97c \uacc4\uc0b0\ud588\ub2e4.<\/li>\n<li>\uc804\uccb4 \ud6a8\uacfc: \uc5f0\uad6c\uc9c4\uc740 \uc77c\ubd80 \uc9d1\ub2e8\uc5d0\uc11c \uc57d\ubb3c \uc0ac\uc6a9\uacfc \ub1cc\uc878\uc911 \ubc1c\uc0dd\ub960\uc774 \ucd5c\ub300 122%\uae4c\uc9c0 \uc99d\uac00\ud55c \uacb0\uacfc\ub97c \ubcf4\uace0\ud588\ub2e4(\uc5f0\uad6c \ubcf4\uace0 \uc218\uce58 \uae30\uc900).<\/li>\n<li>\uc57d\ubb3c\ubcc4 \ucc28\uc774: \ubcf4\uace0\ub41c \ud6a8\uacfc \ud06c\uae30\ub294 \ubb3c\uc9c8\uc5d0 \ub530\ub77c \ud3ed\uc774 \ucef8\ub2e4(\uc608: \uc77c\ubd80 \ubd84\uc11d\uc5d0\uc11c \ub300\ub9c8\u00b7\uc554\ud398\ud0c0\ubbfc\u00b7\ucf54\uce74\uc778 \uad00\ub828 \uc0c1\ub300\uc704\ud5d8 \uc99d\uac00\uac00 37%~96% \ubc94\uc704\ub85c \uc81c\uc2dc\ub428, \uc624\ud53c\uc624\uc774\ub4dc \uad00\ub828 \uc77c\ubd80 \ubd84\uc11d\uc740 174% \uc99d\uac00\uce58 \ubcf4\uace0).<\/li>\n<li>\uc720\uc804\ud559 \ubd84\uc11d: GWAS \uae30\ubc18 \ub3c4\uad6c\ub97c \uc774\uc6a9\ud55c Mendelian randomization \uacb0\uacfc\ub294 \ubb3c\uc9c8\ubcc4\ub85c \uc778\uacfc\uc131\uc744 \uc2dc\uc0ac\ud558\ub294 \uacbd\uc6b0\uc640 \uc720\uc758\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0\uac00 \ud63c\uc7ac\ud588\ub2e4.<\/li>\n<li>\uad6d\ub0b4 \ub9e5\ub77d: \uae30\uc0ac \uc778\uc6a9 \ud1b5\uacc4\uc5d0\uc11c\ub294 16~59\uc138\uc5d0\uc11c \uc57d\ubb3c \uc0ac\uc6a9 \uc720\ubcd1\ub960\uc774 8.8%\ub85c \uc81c\uc2dc\ub418\uc5b4 \uc57d\ubb3c \uad00\ub828 \uac74\uac15\ubd80\ub2f4\uc774 \ubb34\uc2dc\ud560 \uc218 \uc5c6\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4(\uc6d0\ubb38 \ubcf4\ub3c4\uce58).<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>\ubd88\ubc95\uc57d\ubb3c \uc0ac\uc6a9\uacfc \ub1cc\ud608\uad00\uc9c8\ud658\uc758 \uc5f0\uad00\uc131\uc740 \uc218\uc2ed \ub144\uac04 \uad00\ucc30\u00b7\ubcf4\uace0\ub418\uc5b4 \uc654\uc9c0\ub9cc \uc5f0\uad6c\ub9c8\ub2e4 \ud45c\ubcf8\u00b7\ubc29\ubc95\u00b7\uc870\uc815\ubcc0\uc218\uac00 \ub2ec\ub77c \uacb0\uacfc \ud574\uc11d\uc5d0 \ud63c\uc120\uc774 \uc788\uc5c8\ub2e4. \uc2ec\uac01\ud55c \ubb38\uc81c\ub294 \uc80a\uc740 \uc5f0\ub839\uce35\uc5d0\uc11c \ub1cc\uc878\uc911 \ubc1c\uc0dd\uc774 \uc99d\uac00\ud560 \ub54c \uae30\uc800 \uc6d0\uc778\uc73c\ub85c \uc57d\ubb3c \uc0ac\uc6a9\uc774 \uc9c0\ubaa9\ub418\ub294 \uacbd\uc6b0\uac00 \ub298\uc5b4\ub09c\ub2e4\ub294 \uc810\uc774\ub2e4. \uc57d\ubb3c\uc740 \ud608\uad00 \uc218\ucd95, \ud608\uc555 \uae09\uc0c1\uc2b9, \uc2ec\uc7a5\uc131 \uc0c9\uc804\uc6d0 \uc0dd\uc131 \ub4f1 \ub2e4\uc591\ud55c \uae30\uc804\uc73c\ub85c \ub1cc\ud608\ub958\ub97c \uad50\ub780\ud560 \uc218 \uc788\uc5b4 \ub1cc\uc878\uc911 \uc704\ud5d8\uc778\uc790\uac00 \ub41c\ub2e4. \uadf8\ub7ec\ub098 \uad00\ucc30\uc5f0\uad6c\ub9cc\uc73c\ub85c\ub294 \uc57d\ubb3c \uc790\uccb4\uc758 \uc778\uacfc\ud6a8\uacfc\ub97c \ub2e8\uc815\ud558\uae30 \uc5b4\ub835\uace0, \ub3d9\ubc18\ub41c \uc0dd\ud65c\uc2b5\uad00(\ud761\uc5f0\u00b7\uc74c\uc8fc\u00b7\uc601\uc591 \ub4f1)\uc774\ub098 \uc0ac\ud68c\uacbd\uc81c\uc801 \uc694\uc778\uc774 \ud63c\uc785\ub420 \uc218 \uc788\ub2e4.<\/p>\n<p>\uc774\uc5d0 \ub530\ub77c \uc5f0\uad6c\uc790\ub4e4\uc740 \ub2e8\uc21c \uc5f0\uad00\uc744 \ub118\uc5b4\uc11c \uc778\uacfc\uad00\uacc4\ub97c \ud0d0\uc0c9\ud558\uae30 \uc704\ud574 \uba54\ud0c0\ubd84\uc11d\uacfc \ud568\uaed8 \uc720\uc804\ud559\uc801 \uc811\uadfc\ubc95(Mendelian randomization)\uc744 \ubcd1\ud589\ud588\ub2e4. \uc774 \ubc29\ubc95\uc740 \uc57d\ubb3c \uc0ac\uc6a9\uc5d0 \ub300\ud55c \uc720\uc804\uc801 \uc18c\uc778\uc744 \ub3c4\uad6c\ubcc0\uc218\ub85c \uc0bc\uc544 \uad00\ucc30\uc801 \ud63c\ub780\uc744 \uc904\uc774\ub294 \uc2dc\ub3c4\ub85c, \uc784\uc0c1\uc801\u00b7\uc5ed\ud559\uc801 \uc99d\uac70\ub97c \ubcf4\uac15\ud558\ub294 \uc5ed\ud560\uc744 \ud55c\ub2e4. \ub3d9\uc2dc\uc5d0 \uad6d\ub0b4\uc678\uc5d0\uc11c \uc57d\ubb3c \uc720\ubcd1\ub960\uc774 \ubcc0\ub3d9\ud558\uace0 \uc788\uc5b4 \uacf5\uc911\ubcf4\uac74\uc801 \ub300\uc751\uc758 \ud544\uc694\uc131\uc774 \ucee4\uc9c0\uace0 \uc788\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uba3c\uc800 \uccb4\uacc4\uc801 \ubb38\ud5cc\uac80\uc0c9\uc744 \ud1b5\ud574 \uad00\ucc30\uc5f0\uad6c 32\uac74\uc744 \uc120\ubcc4\ud574 \uba54\ud0c0\ubd84\uc11d\uc744 \uc218\ud589\ud588\ub2e4. \uac01 \uc5f0\uad6c\uc758 \uc124\uacc4(\ucf54\ud638\ud2b8\u00b7\ucf00\uc774\uc2a4\ucee8\ud2b8\ub864), \uc5f0\ub839\uce35, \ucd94\uc801\uae30\uac04, \uc57d\ubb3c \ubd84\ub958\ub97c \uae30\uc900\uc73c\ub85c \ud6a8\uacfc\ud06c\uae30\ub97c \ud1b5\ud569\ud588\uace0, \ubb3c\uc9c8\ubcc4 \ud558\uc704\ubd84\uc11d\ub3c4 \uc2dc\ub3c4\ud588\ub2e4. \ud1b5\ud569 \uacb0\uacfc \uc77c\ubd80 \uc57d\ubb3c \uc0ac\uc6a9\uc9d1\ub2e8\uc5d0\uc11c \ub1cc\uc878\uc911 \ubc1c\uc0dd \uc704\ud5d8\uc774 \ube44\uc0ac\uc6a9\uc790 \ub300\ube44 \uc720\uc758\ud558\uac8c \ub192\uc558\ub2e4.<\/p>\n<p>\uc774\uc640 \ubcd1\ud589\ud574 \uc5f0\uad6c\uc9c4\uc740 \uacf5\uac1c\ub41c GWAS(\uc720\uc804\uccb4 \uc5f0\uad00 \uc5f0\uad6c) \ub370\uc774\ud130\ub97c \uc774\uc6a9\ud574 \uc57d\ubb3c \uc0ac\uc6a9 \uad00\ub828 \uc720\uc804\uc801 \uc9c0\ud45c\ub97c \ub3c4\uad6c\ubcc0\uc218\ub85c \ud55c Mendelian randomization \ubd84\uc11d\uc744 \uc2e4\uc2dc\ud588\ub2e4. \uc774 \ubd84\uc11d\uc740 \ud2b9\uc815 \ubb3c\uc9c8\uacfc \ub1cc\uc878\uc911 \uc0ac\uc774\uc5d0 \uc720\uc804\uc801 \uc18c\uc778\uc774 \ub9e4\uac1c\ud558\ub294 \uc778\uacfc\uad00\uacc4 \uc2e0\ud638\uac00 \uc788\ub294\uc9c0\ub97c \uac80\ud1a0\ud558\ub824\ub294 \uc2dc\ub3c4\uc600\ub2e4. \uacb0\uacfc\ub294 \ubb3c\uc9c8\ubcc4\ub85c \uc5c7\uac08\ub838\uace0, \uc77c\ubd80\uc5d0\uc11c\ub294 \uc778\uacfc\uc131\uc744 \uc2dc\uc0ac\ud558\ub294 \uadfc\uac70\uac00 \ubc1c\uacac\ub418\uc5c8\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 \ub610\ud55c \ubbfc\uac10\ub3c4 \ubd84\uc11d\uacfc \uc774\uc9c8\uc131 \uac80\ud1a0\ub97c \ud1b5\ud574 \uc5f0\uad6c \uac04 \ucc28\uc774\ub97c \ud655\uc778\ud588\ub2e4. \uc5f0\uad6c\ub4e4\uc740 \ud45c\ubcf8\uad6c\uc131, \uc57d\ubb3c \ub178\ucd9c\uc758 \uc815\uc758, \ub1cc\uc878\uc911 \uc544\ud615(\ud5c8\ud608\uc131\u00b7\ucd9c\ud608\uc131) \uad6c\ubd84 \ub4f1\uc5d0 \ucc28\uc774\uac00 \uc788\uc5b4 \ud1b5\ud569\ud574\ub3c4 \ud574\uc11d\uc0c1\uc758 \ud55c\uacc4\uac00 \uc874\uc7ac\ud55c\ub2e4\uace0 \ubc1d\ud614\ub2e4. \uc800\uc790\ub4e4\uc740 \ucd94\uac00\uc801\uc778 \uc804\ud5a5\uc801 \uc5f0\uad6c\uc640 \uc815\ud655\ud55c \ub178\ucd9c \uce21\uc815\uc758 \ud544\uc694\uc131\uc744 \uac15\uc870\ud588\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uccab\uc9f8, \uc774\ubc88 \uc885\ud569\ubd84\uc11d\uc740 \uc784\uc0c1\u00b7\uc751\uae09\uc758\ub8cc \ud604\uc7a5\uc5d0\uc11c \uc57d\ubb3c \uc0ac\uc6a9\ub825\uc744 \ubcd1\ub825 \uc870\uc0ac\uc5d0 \ud3ec\ud568\ud558\ub294 \uc911\uc694\uc131\uc744 \uc7ac\ud655\uc778\uc2dc\ud0a8\ub2e4. \uc80a\uc740\uce35 \ub1cc\uc878\uc911 \ud658\uc790\uc5d0\uc11c \uc54c\ub824\uc9c4 \uc704\ud5d8\uc694\uc778\uc774 \uc801\uc744 \ub54c \uc57d\ubb3c \ub178\ucd9c \uc5ec\ubd80\uac00 \uc9c4\ub2e8\u00b7\uce58\ub8cc \ubc29\ud5a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\ub2e4. \uc751\uae09\ucc98\uce58\ub098 \ud608\uc804\uc6a9\ud574 \ub4f1\uc758 \uacb0\uc815\uc5d0 \uc55e\uc11c \uc6d0\uc778 \uaddc\uba85\uc740 \uc608\ud6c4\uc640 \uc7ac\ubc1c \uc608\ubc29\uc5d0 \uc911\uc694\ud558\ub2e4.<\/p>\n<p>\ub458\uc9f8, \uacf5\uc911\ubcf4\uac74 \uce21\uba74\uc5d0\uc11c\ub294 \uc57d\ubb3c \uc0ac\uc6a9 \uc608\ubc29\uacfc \uc870\uae30 \uac1c\uc785\uc758 \ud544\uc694\uc131\uc774 \ubd80\uac01\ub41c\ub2e4. \uc57d\ubb3c \uc0ac\uc6a9\uc790 \uc9d1\ub2e8\uc5d0\uc11c \ub1cc\uc878\uc911 \uc704\ud5d8\uc774 \uc99d\uac00\ud55c\ub2e4\uba74 \uc608\ubc29\uad50\uc721\u00b7\uac80\uc9c4\u00b7\uc758\ub8cc\uc811\uadfc\uc131 \uac1c\uc120\uc744 \ud1b5\ud574 \ubd80\ub2f4\uc744 \uc904\uc77c \uc5ec\uc9c0\uac00 \uc788\ub2e4. \ud2b9\ud788 \ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc \ub4f1 \uac01 \uc57d\ubb3c\uc758 \uc791\uc6a9\uae30\uc804(\ud608\uad00\uc218\ucd95\u00b7\uc2ec\uc7a5\ud569\ubcd1\uc99d \uc720\ubc1c \ub4f1)\uc5d0 \ub530\ub978 \ub9de\ucda4\ud615 \uc804\ub7b5\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p>\uc14b\uc9f8, \uc815\ucc45\uc801 \ud568\uc758\ub85c\ub294 \uc57d\ubb3c \uad00\ub828 \uc758\ub8cc\uc11c\ube44\uc2a4 \uc5f0\uacc4 \uac15\ud654\uc640 \uc5ed\ud559 \ubaa8\ub2c8\ud130\ub9c1 \ud655\ucda9\uc774 \uc694\uad6c\ub41c\ub2e4. \ubc95\u00b7\uc0ac\ubc95\uc801 \uc811\uadfc\ub9cc\uc73c\ub85c\ub294 \uac74\uac15 \uc190\uc0c1\uc744 \uc904\uc774\ub294 \ub370 \ud55c\uacc4\uac00 \uc788\uc73c\ubbc0\ub85c \uacf5\uc911\ubcf4\uac74\u00b7\uc758\ub8cc \uc2dc\uc2a4\ud15c\uacfc\uc758 \uc5f0\uacc4\uac00 \uc911\uc694\ud558\ub2e4. \uc5f0\uad6c\uc801\uc73c\ub860 \ud5a5\ud6c4 \ub300\uaddc\ubaa8 \uc804\ud5a5\uc801 \ucf54\ud638\ud2b8\uc640 \ud45c\uc900\ud654\ub41c \uc57d\ubb3c \ub178\ucd9c \uce21\uc815, \uc544\ud615\ubcc4 \uc704\ud5d8 \ubd84\uc11d\uc774 \ubcf4\uc644\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\ubb3c\uc9c8\uad70<\/th>\n<th>\ubcf4\uace0\ub41c \uc0c1\ub300\uc704\ud5d8(\uc608\uc2dc)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\uc804\uccb4(\ud1b5\ud569\uce58)<\/td>\n<td>+122% (\uc5f0\uad6c \ubcf4\uace0\uce58)<\/td>\n<\/tr>\n<tr>\n<td>\ub300\ub9c8(\uce78\ub098\ube44\uc2a4)<\/td>\n<td>\uc99d\uac00\ud3ed 37% ~ 96% \ubc94\uc704(\uc5f0\uad6c\ubcc4 \uc0c1\uc774)<\/td>\n<\/tr>\n<tr>\n<td>\ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc(\uac01\uc885 \uc790\uadf9\uc81c)<\/td>\n<td>\uc0c1\ub300\uc704\ud5d8 \uc720\uc758 \uc99d\uac00(\uc5f0\uad6c\ubcc4 \ucc28\uc774 \uc874\uc7ac)<\/td>\n<\/tr>\n<tr>\n<td>\uc624\ud53c\uc624\uc774\ub4dc<\/td>\n<td>\uc77c\ubd80 \ubd84\uc11d: +174% \ubcf4\uace0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \ub17c\ubb38\uacfc \ubcf4\ub3c4\uc5d0\uc11c \uc81c\uc2dc\ub41c \ud1b5\ud569\u00b7\ud558\uc704\ubd84\uc11d\uc758 \ub300\ud45c \uc218\uce58\ub97c \uc815\ub9ac\ud55c \uac83\uc774\ub2e4. \uc5f0\uad6c\ub4e4 \uac04 \uc124\uacc4\u00b7\ud45c\ubcf8\uc758 \uc774\uc9c8\uc131\uc774 \ucee4 \uc218\uce58\uc758 \ubc94\uc704\uac00 \ub113\uace0, \ud2b9\uc815 \uc218\uce58\ub294 \uac1c\ubcc4 \uc5f0\uad6c\u00b7\ud558\uc704\ubd84\uc11d\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9c4\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c \uacb0\uacfc\uc5d0 \ub300\ud55c \uacf5\uc2dd\uc801\u00b7\uc804\ubb38\uc801 \ubc18\uc751\uc740 \uc2e0\uc911\ud55c \uacbd\uace0\uc640 \ud568\uaed8 \ud6c4\uc18d\uc5f0\uad6c \ucd09\uad6c\ub85c \uc694\uc57d\ub41c\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\uc774\ubc88 \uba54\ud0c0\ubd84\uc11d\uc740 \ubd88\ubc95\uc57d\ubb3c \uc0ac\uc6a9\uacfc \ub1cc\uc878\uc911\uacfc\uc758 \uc5f0\uad00\uc131\uc744 \uac15\ud558\uac8c \uc2dc\uc0ac\ud55c\ub2e4. \ub2e4\ub9cc \uad00\ucc30\uc801 \ud55c\uacc4\ub97c \ubc30\uc81c\ud558\uae30 \uc5b4\ub824\uc6cc \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4.&#8221;<\/p>\n<p><cite>Megan Ritson \uc678(\uc5f0\uad6c\uc9c4)<\/cite><\/p><\/blockquote>\n<p>\uc5f0\uad6c\uc9c4 \ubc1c\uc5b8\uc740 \ubd84\uc11d \ubc29\ubc95\uc758 \uac15\uc810(\ub300\uaddc\ubaa8 \ud1b5\ud569, MR \uc811\uadfc)\uacfc \ud55c\uacc4(\uc774\uc9c8\uc131, \uc794\uc874 \uad50\ub780)\ub97c \ub3d9\uc2dc\uc5d0 \uc778\uc815\ud558\ub294 \ub9e5\ub77d\uc5d0\uc11c \uc81c\uc2dc\ub418\uc5c8\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\uc80a\uc740 \uc5f0\ub839\ub300 \ub1cc\uc878\uc911\uc758 \uc6d0\uc778 \ud0d0\uc0c9\uc5d0 \uc57d\ubb3c\ub825 \uc870\uc0ac\ub294 \ud544\uc218\uc801\uc774\ub2e4. \uc751\uae09\u00b7\uc608\ubc29\uc758\ub8cc \uccb4\uacc4\uc5d0\uc11c \uc774\ub97c \ubc18\uc601\ud574\uc57c \ud55c\ub2e4.&#8221;<\/p>\n<p><cite>\uad6d\ub0b4 \uc2e0\uacbd\uacfc \uc804\ubb38\uc758(\uc775\uba85 \uc81c\uacf5 \ubc1c\uc5b8 \uc694\uc57d)<\/cite><\/p><\/blockquote>\n<p>\uc804\ubb38\uac00\ub294 \uc784\uc0c1 \ud604\uc7a5\uc5d0\uc11c\uc758 \uc801\uc6a9 \uac00\ub2a5\uc131\uacfc \uacf5\uc911\ubcf4\uac74\uc801 \ub300\uc751\uc744 \uac15\uc870\ud558\uba70, \uc57d\ubb3c\ub825 \uccad\ucde8\uc758 \ud45c\uc900\ud654 \ud544\uc694\uc131\uc744 \ub367\ubd99\uc600\ub2e4.<\/p>\n<h2>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\u00b7\ubc29\ubc95\ub860<\/summary>\n<p>Mendelian randomization\uc740 \uc720\uc804\uc801 \ubcc0\uc774\ub97c \ub3c4\uad6c\ubcc0\uc218\ub85c \uc0bc\uc544 \ub178\ucd9c(\uc608: \uc57d\ubb3c \uc0ac\uc6a9)\uacfc \uacb0\uacfc(\uc608: \ub1cc\uc878\uc911) \uc0ac\uc774\uc758 \uc778\uacfc\uad00\uacc4\ub97c \ud0d0\uc0c9\ud558\ub294 \uc5ed\ud559\uae30\ubc95\uc774\ub2e4. \uc774 \ubc29\ubc95\uc740 \uad00\ucc30\uc5f0\uad6c\uc5d0\uc11c \ud754\ud788 \ubb38\uc81c\ub418\ub294 \uad50\ub780(confounding)\uc744 \uc77c\ubd80 \uc904\uc77c \uc218 \uc788\uc73c\ub098, \ub3c4\uad6c\ubcc0\uc218\uc758 \uc801\uc808\uc131(\uc720\uc804\uc801 \uc9c0\ud45c\uac00 \ub178\ucd9c\uc5d0\ub9cc \uc601\ud5a5)\uc744 \uac00\uc815\ud574\uc57c \ud558\uace0 \ud1b5\uacc4\uc801 \uac80\uc815\ub825\uc774 \uc694\uad6c\ub41c\ub2e4. \uba54\ud0c0\ubd84\uc11d\uc740 \uc5ec\ub7ec \uc5f0\uad6c\uc758 \ud6a8\uacfc\ud06c\uae30\ub97c \ud1b5\ud569\ud574 \ud3c9\uade0\ud6a8\uacfc\ub97c \ucd94\uc815\ud558\uc9c0\ub9cc \uc5f0\uad6c\uac04 \uc774\uc9c8\uc131(\uc124\uacc4\u00b7\ud45c\ubcf8\u00b7\uce21\uc815 \ubc29\ubc95 \ucc28\uc774)\uc744 \uace0\ub824\ud574\uc57c \ud55c\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<\/h2>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\uc77c\ubd80 \uc81c\uc2dc\ub41c \uc218\uce58(\uc608: \uc804\uccb4 +122%, \uc624\ud53c\uc624\uc774\ub4dc +174% \ub4f1)\ub294 \uc6d0\ubb38 \uba54\ud0c0\ubd84\uc11d\uc758 \ud558\uc704\ubd84\uc11d \ub610\ub294 \ud2b9\uc815 \uc5f0\uad6c \uacb0\uacfc\ub97c \uc694\uc57d\ud55c \uac83\uc73c\ub85c, \ud45c\uc900\ud654\ub41c \ub2e8\uc77c \ucd94\uc815\uce58\uac00 \uc544\ub2d0 \uc218 \uc788\ub2e4.<\/li>\n<li>Mendelian randomization \uacb0\uacfc \uc911 \uc5b4\ub5a4 \ubb3c\uc9c8\uc5d0\uc11c \uc77c\uad00\ub41c \uc778\uacfc\uc131 \uc2e0\ud638\uac00 \uc788\uc5c8\ub294\uc9c0\ub294 \ubb3c\uc9c8\ubcc4\ub85c \uc5c7\uac08\ub9ac\uba70, \ubaa8\ub4e0 \uc57d\ubb3c\uc5d0 \ub300\ud574 \uc778\uacfc\uc131\uc774 \ud655\uc815\ub41c \uac83\uc740 \uc544\ub2c8\ub2e4.<\/li>\n<li>\uad6d\ub0b4 \uc720\ubcd1\ub960(16~59\uc138 8.8%\u00b7290\ub9cc\uba85 \ub4f1)\uc740 \ubcf4\ub3c4 \uc778\uc6a9\uce58\ub85c\uc11c \ud45c\ubcf8\u00b7\uc870\uc0ac\ubc29\ubc95\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9c8 \uc218 \uc788\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \uc885\ud569\uc5f0\uad6c\ub294 \ubd88\ubc95\uc57d\ubb3c \uc0ac\uc6a9\uacfc \ub1cc\uc878\uc911 \ubc1c\uc0dd \uc704\ud5d8 \uac04 \uc720\uc758\ud55c \uc5f0\uad00\uc131\uc744 \ub2e4\uc2dc \ud655\uc778\ud574 \uc758\ub8cc\u00b7\uacf5\uc911\ubcf4\uac74 \ucc28\uc6d0\uc758 \uad00\uc2ec\uc744 \ud658\uae30\uc2dc\ud0a8\ub2e4. \uc57d\ubb3c\ubcc4\ub85c \uc704\ud5d8\uc758 \ud06c\uae30\uc640 \uc778\uacfc\uc131\uc758 \uac15\ub3c4\uac00 \ub2ec\ub77c \ucd94\uac00\uc801\uc778 \uc804\ud5a5\uc801 \uc5f0\uad6c\uc640 \ud45c\uc900\ud654\ub41c \uce21\uc815\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n<p>\uc784\uc0c1\uc801\uc73c\ub85c\ub294 \ub1cc\uc878\uc911 \ud658\uc790 \ubcd1\ub825\uc870\uc0ac\uc5d0\uc11c \uc57d\ubb3c \uc0ac\uc6a9\ub825\uc744 \ubc18\ub4dc\uc2dc \ud655\uc778\ud558\uace0, \uc608\ubc29\uc815\ucc45 \uce21\uba74\uc5d0\uc11c\ub294 \uc57d\ubb3c \uc0ac\uc6a9 \uc5b5\uc81c\u00b7\uc870\uae30 \uac1c\uc785\u00b7\uc758\ub8cc \uc5f0\uacc4 \uac15\ud654\uac00 \uc694\uad6c\ub41c\ub2e4. \uc5f0\uad6c\uc790\u00b7\uc784\uc0c1\uc758\u00b7\uc815\ucc45\uc785\uc548\uc790\uac00 \ud611\ub825\ud574 \ud6c4\uc18d \uc5f0\uad6c\uc640 \uc2e4\ubb34 \uc9c0\uce68\uc744 \ub9c8\ub828\ud558\ub294 \uac83\uc774 \uc2dc\uae09\ud558\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"http:\/\/dx.doi.org\/10.1177\/17474930261418926\" target=\"_blank\" rel=\"noopener\">International Journal of Stroke \u2014 \ud559\uc220\uc9c0(\uc5f0\uad6c \uc6d0\ubb38, Megan Ritson et al.)<\/a><\/li>\n<li><a href=\"https:\/\/news.nate.com\/view\/20260309n05854\" target=\"_blank\" rel=\"noopener\">\ub124\uc774\ud2b8 \ub274\uc2a4(\uc5b8\ub860 \ubcf4\ub3c4)<\/a><\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \ucd5c\uadfc \uad6d\uc81c \ud559\uc220\uc9c0\uc5d0 \uc2e4\ub9b0 \uccb4\uacc4\uc801 \ubb38\ud5cc\uace0\ucc30\u00b7\uba54\ud0c0\ubd84\uc11d\uacfc \uc720\uc804\uc790\ub3c4\uad6c \ubd84\uc11d(Mendelian randomization)\uc740 \ub300\ub9c8(\uce78\ub098\ube44\uc2a4), \ucf54\uce74\uc778, \uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c \uc0ac\uc6a9\uc790\uac00 \ube44\uc0ac\uc6a9\uc790\ubcf4\ub2e4 \ub1cc\uc878\uc911 \uc704\ud5d8\uc774 \uc720\uc758\ud558\uac8c \ub192\ub2e4\ub294 \uacb0\uacfc\ub97c \ubcf4\uace0\ud588\ub2e4. \uc5f0\uad6c\ub294 \uad00\ucc30\uc5f0\uad6c 32\uac74\uc744 \uc885\ud569\ud558\uace0 \uc720\uc804\ud559 \uae30\ubc18 \ubd84\uc11d\uc744 \ubcd1\ud589\ud574 \uc77c\ubd80 \uc57d\ubb3c\uacfc \ub1cc\uc878\uc911 \uc0ac\uc774\uc758 \uc778\uacfc\uad00\uacc4 \uac00\ub2a5\uc131\ub3c4 \uac80\ud1a0\ud588\ub2e4. \uad6d\ub0b4 \uc790\ub8cc\uc640 \uacb0\ud569\ud558\uba74 \ud2b9\uc815 \uc5f0\ub839\ub300\uc5d0\uc11c \uc57d\ubb3c \uc0ac\uc6a9\uc758 \uc720\ubcd1\ub960\uc774 \ub192\uc544 \uad00\ub828 \uacf5\uc911\ubcf4\uac74 \uc601\ud5a5\uc774 \ud074 \uac83\uc73c\ub85c \ucd94\uc815\ub41c\ub2e4. \ud575\uc2ec &#8230; <a title=\"\ub300\ub9c8\u00b7\ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c, \ub1cc\uc878\uc911 \uc704\ud5d8 \ud06c\uac8c \ub192\uc5ec\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/drug-stroke-risk-meta-analysis\/\" aria-label=\"\ub300\ub9c8\u00b7\ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c, \ub1cc\uc878\uc911 \uc704\ud5d8 \ud06c\uac8c \ub192\uc5ec\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":9785,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"\ub300\ub9c8\u00b7\ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c, \ub1cc\uc878\uc911 \uc704\ud5d8\u2191 - \uac74\uac15\ud3ec\ucee4\uc2a4","rank_math_description":"\uba54\ud0c0\ubd84\uc11d\uacfc \uc720\uc804\ud559\uc801 \ubd84\uc11d\uc744 \uc885\ud569\ud55c \uc5f0\uad6c\ub294 \ub300\ub9c8\u00b7\ucf54\uce74\uc778\u00b7\uc554\ud398\ud0c0\ubbfc \ub4f1 \ubd88\ubc95\uc57d\ubb3c \uc0ac\uc6a9\uc774 \ub1cc\uc878\uc911 \uc704\ud5d8\uc744 \uc720\uc758\ud558\uac8c \ub192\uc778\ub2e4\uace0 \ubcf4\uace0\ud588\ub2e4. \uad6d\ub0b4\uc678 \ubcf4\uac74\ub300\uc751\uacfc \ud6c4\uc18d \uc5f0\uad6c\uc758 \ud544\uc694\uc131\uc744 \uc815\ub9ac\ud569\ub2c8\ub2e4.","rank_math_focus_keyword":"\ub9c8\uc57d, \ub1cc\uc878\uc911, \ub300\ub9c8, \ucf54\uce74\uc778, \uc554\ud398\ud0c0\ubbfc","footnotes":""},"categories":[2],"tags":[],"class_list":["post-9789","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9789","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=9789"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9789\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/9785"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=9789"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=9789"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=9789"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}