{"id":9889,"date":"2026-03-10T10:09:16","date_gmt":"2026-03-10T01:09:16","guid":{"rendered":"https:\/\/readtrends.com\/ko\/cd38-hepatitis-b-reactivation-myeloma\/"},"modified":"2026-03-10T10:09:16","modified_gmt":"2026-03-10T01:09:16","slug":"cd38-hepatitis-b-reactivation-myeloma","status":"publish","type":"post","link":"https:\/\/readtrends.com\/ko\/cd38-hepatitis-b-reactivation-myeloma\/","title":{"rendered":"CD38 \ud56d\uccb4 \uce58\ub8cc \ubc1b\uc740 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ub9de\ucda4\ud615 \uc608\ubc29 \uc804\ub7b5 \uc81c\uc2dc &#8211; \ud6c4\uc0dd\uc2e0\ubcf4"},"content":{"rendered":"<article>\n<h2>\ud575\uc2ec \uc694\uc57d<\/h2>\n<p>\uac00\ud1a8\ub9ad\ub300 \uc11c\uc6b8\uc131\ubaa8\ubcd1\uc6d0 \uc131\ud544\uc218 \uad50\uc218\ud300(\uc81c1\uc800\uc790 \ud0c1\uad8c\uc6a9 \uc784\uc0c1\uac15\uc0ac)\uc740 2015\ub144~2025\ub144 anti-CD38 \ud56d\uccb4 \uce58\ub8cc\ub97c \ubc1b\uc740 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ud658\uc790 \uc911 \uacfc\uac70 B\ud615\uac04\uc5fc \ub178\ucd9c\uc790(anti-HBc \uc591\uc131, HBsAg \uc74c\uc131) 180\uba85\uc744 \ud6c4\ud5a5\uc801\uc73c\ub85c \ubd84\uc11d\ud574, \uc784\uc0c1\uc801\uc73c\ub85c \uc758\ubbf8 \uc788\ub294 \uc7ac\ud65c\uc131\ud654 \uace0\uc704\ud5d8 \ud558\uc704\uad70\uc744 \uaddc\uba85\ud588\ub2e4. \ucd94\uc801 \uc911\uc559\uac12\uc740 14.5\uac1c\uc6d4\uc774\uba70, \uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c\ub97c \ud22c\uc5ec\ud55c 14\uba85\uc5d0\uc11c\ub294 \uc7ac\ud65c\uc131\ud654\uac00 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\ub2e4. \uc608\ubc29 \ubbf8\uc2dc\ud589 166\uba85\uc5d0\uc11c\ub294 13\uba85(7.8%)\uc5d0\uc11c \uc7ac\ud65c\uc131\ud654\uac00 \ubc1c\uc0dd\ud588\uace0, anti-HBs \uc218\uce58\uc640 \ubcd1\uae30(\uc7ac\ubc1c\u00b7\ubd88\uc751)\uac00 \ud575\uc2ec \uc704\ud5d8\uc778\uc790\ub85c \ud655\uc778\ub410\ub2e4. \uc800\ud56d\uad70\uc744 \uc138\ubd84\ud654\ud55c \uacb0\uacfc \uace0\uc704\ud5d8\uad70\uc758 \ub2e8\uae30 \ubc1c\uc0dd\ub960\uc774 \uc720\uc758\ud558\uac8c \ub192\uc544 \uc120\ubcc4\uc801 \uc608\ubc29\uc804\ub7b5\uc758 \ud544\uc694\uc131\uc774 \uc81c\uae30\ub410\ub2e4.<\/p>\n<h2>\ud575\uc2ec \uc0ac\uc2e4<\/h2>\n<ul>\n<li>\uc5f0\uad6c\ub300\uc0c1\uc740 anti-CD38 \uce58\ub8cc\ub97c \ubc1b\uc740 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ud658\uc790 709\uba85 \uc911 \uacfc\uac70 B\ud615\uac04\uc5fc \ub178\ucd9c\uc790 180\uba85(anti-HBc \uc591\uc131, HBsAg \uc74c\uc131)\uc774\ub2e4.<\/li>\n<li>\uc911\uc559 \ucd94\uc801\uae30\uac04\uc740 14.5\uac1c\uc6d4\uc774\uba70, \uc774 \uc911 14\uba85(7.8%)\uc740 \uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c\ub97c \ud22c\uc5ec\ubc1b\uc558\ub2e4.<\/li>\n<li>\uc608\ubc29 \uce58\ub8cc \ubbf8\uc2dc\ud589\uad70 166\uba85\uc5d0\uc11c B\ud615\uac04\uc5fc \uc7ac\ud65c\uc131\ud654\ub294 13\uba85(7.8%)\uc774\uc5c8\ub2e4(\uc720\ub7fd\uac04\ud559\ud68c(EASL) \uae30\uc900\uc758 \uc911\ub4f1\ub3c4 \uc704\ud5d8 \ubc94\uc704 1~10%\uc5d0 \ud574\ub2f9).<\/li>\n<li>\ub2e4\ubcc0\ub7c9 \ubd84\uc11d \uacb0\uacfc, \uae30\uc800 anti-HBs \uc218\uce58 <100 IU\/L\uc640 \uc7ac\ubc1c\u00b7\ubd88\uc751 \ub2e8\uacc4\uc5d0\uc11c\uc758 anti-CD38 \uc2dc\uc791\uc774 \ub3c5\ub9bd\uc801 \uc7ac\ud65c\uc131\ud654 \uc704\ud5d8\uc778\uc790\ub85c \ud655\uc778\ub410\ub2e4.<\/li>\n<li>\uc704 \ub450 \uc778\uc790\ub97c \uacb0\ud569\ud574 \uce35\ud654\ud588\uc744 \ub54c \uace0\uc704\ud5d8\uad70(anti-HBs <100 IU\/L + \uc7ac\ubc1c\/\ubd88\uc751)\uc740 \uc911\uc559 \ucd94\uc801\uae30\uac04 10.6\uac1c\uc6d4 \ub3d9\uc548 \uc57d 19.6%\uc5d0\uc11c \uc7ac\ud65c\uc131\ud654\ub97c \ubcf4\uc600\uace0, 24\uac1c\uc6d4 \ub204\uc801 \ubc1c\uc0dd\ub960\uc740 \uc57d 40%\ub85c \ucd94\uc0b0\ub410\ub2e4.<\/li>\n<li>\uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c\ub97c \ud22c\uc5ec\ud55c 14\uba85\uc5d0\uc11c\ub294 \uc7ac\ud65c\uc131\ud654\u00b7\uc911\uc99d \uac04\uc5fc\u00b7\uac04 \uad00\ub828 \uc0ac\ub9dd\uc774 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\ub2e4.<\/li>\n<li>\uc911\uc99d \uac04\uc5fc \ubc0f \uac04 \uad00\ub828 \uc0ac\ub9dd\uc740 \uc608\ubc29 \ubbf8\uc2dc\ud589\uad70\uc5d0\uc11c\ub9cc \ubc1c\uc0dd\ud588\uc73c\uba70, \uc8fc\ub85c \uace0\uc704\ud5d8\uad70\uc5d0\uc11c \uc9d1\uc911\ub410\ub2e4.<\/li>\n<li>\uc5f0\uad6c \uacb0\uacfc\ub294 Journal of Hepatology(IF 33.0)\uc5d0 \uac8c\uc7ac\ub418\uc5c8\uace0, EASL \uac00\uc774\ub4dc\ub77c\uc778 \uad00\ub828 \uc784\uc0c1 \uc758\uacac \uc81c\ucd9c\ub3c4 \ubcd1\ud589\ub410\ub2e4.<\/li>\n<\/ul>\n<h2>\uc0ac\uac74 \ubc30\uacbd<\/h2>\n<p>B\ud615\uac04\uc5fc\uc740 \uc804 \uc138\uacc4\uc801\uc73c\ub85c \uc57d 2\uc5b5 5,700\ub9cc \uba85\uc758 \ub9cc\uc131 \uac10\uc5fc\uc790\ub97c \uac00\uc9c4 \uc9c8\ud658\uc73c\ub85c, WHO \uc9d1\uacc4\uc0c1 \uc5f0\uac04 \uc57d 110\ub9cc \uba85\uc774 B\ud615\uac04\uc5fc \uad00\ub828 \ud569\ubcd1\uc99d\uc73c\ub85c \uc0ac\ub9dd\ud55c\ub2e4. \uacfc\uac70\uc5d0 \uac10\uc5fc\ub41c \ub4a4 \ud45c\uba74\ud56d\uc6d0\uc740 \uc74c\uc131\uc774\ub098 \ud56d\uccb4 \ubcf4\uc720 \uc0c1\ud0dc\uc778 \uacbd\uc6b0, \uba74\uc5ed\uc5b5\uc81c \uc0c1\ud669\uc5d0\uc11c HBV\uac00 \uc7ac\ud65c\uc131\ud654\ub420 \uc218 \uc788\uc5b4 \uae09\uc131 \uac04\uc5fc\u00b7\uac04\ubd80\uc804\uacfc \uac19\uc740 \uce58\uba85\uc801 \ud569\ubcd1\uc99d\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc74c\uc774 \uc798 \uc54c\ub824\uc838 \uc788\ub2e4. \uae30\uc874 \ubb38\ud5cc\uc740 \ud56d\uc554\uc81c\u00b7\uba74\uc5ed\uc5b5\uc81c\uc81c \ud22c\uc5ec \uc2dc \uc7ac\ud65c\uc131\ud654 \uc704\ud5d8\uc744 \uc9c0\uc801\ud574 \uc654\uc73c\ub098, anti-CD38 \uacc4\uc5f4 \ud56d\uccb4\uc5d0 \ub300\ud55c \uad6c\uccb4\uc801 \uc2e4\uc0ac\uc6a9 \ub370\uc774\ud130\ub294 \uc0c1\ub300\uc801\uc73c\ub85c \ubd80\uc871\ud588\ub2e4.<\/p>\n<p>anti-CD38 \ud56d\uccb4\ub294 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \uce58\ub8cc\uc5d0\uc11c 1\ucc28\uc694\ubc95\ubd80\ud130 \uc7ac\ubc1c\u00b7\ubd88\uc751\uae4c\uc9c0 \ud3ed\ub113\uac8c \uc0ac\uc6a9\ub418\ub294 \ud575\uc2ec \uc57d\uc81c\ub2e4. CD38\uc740 \uace8\uc218\uc885\uc138\ud3ec\ubfd0 \uc544\ub2c8\ub77c \uc815\uc0c1 \ud615\uc9c8\uc138\ud3ec\u00b7\uba74\uc5ed\uc870\uc808\uc138\ud3ec\uc5d0\ub3c4 \ubc1c\ud604\ub418\uc5b4 \uc788\uc5b4 \uac15\ub825\ud55c \uba74\uc5ed\uc870\uc808 \ud6a8\uacfc\uc640 \ud568\uaed8 HBV\uc5d0 \ub300\ud55c \ubc29\uc5b4 \uba74\uc5ed\uc744 \uad50\ub780\ud560 \uac00\ub2a5\uc131\uc774 \uc81c\uae30\ub41c\ub2e4. \uc774\uc5d0 \ub530\ub77c anti-CD38 \uce58\ub8cc\uad70\uc5d0\uc11c\uc758 HBV \uc7ac\ud65c\uc131\ud654 \ubc1c\uc0dd\ub960\uacfc \ub204\uad6c\uc5d0\uac8c \uc608\ubc29\uce58\ub8cc\uac00 \ud544\uc694\ud55c\uc9c0\uc5d0 \ub300\ud55c \uba85\ud655\ud55c \uadfc\uac70 \ub9c8\ub828\uc774 \uc784\uc0c1\uc801 \uacfc\uc81c\ub85c \ub0a8\uc544 \uc788\uc5c8\ub2e4.<\/p>\n<h2>\uc8fc\uc694 \uc0ac\uac74<\/h2>\n<p>\uc5f0\uad6c\ud300\uc740 2015\ub144 1\uc6d4\ubd80\ud130 2025\ub144 12\uc6d4\uae4c\uc9c0 anti-CD38 \uce58\ub8cc\ub97c \ubc1b\uc740 \ud658\uc790 \ucf54\ud638\ud2b8 709\uba85 \uc911 \uacfc\uac70 HBV \ub178\ucd9c\uc790 180\uba85\uc744 \uc120\ubcc4\ud574 \ud6c4\ud5a5\uc801 \ubd84\uc11d\uc744 \uc218\ud589\ud588\ub2e4. \uc804\uccb4\uc5d0\uc11c \uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c\ub97c \ud22c\uc5ec\ud55c \ud658\uc790\ub294 14\uba85, \ub098\uba38\uc9c0 166\uba85\uc740 \uc608\ubc29 \uc5c6\uc774 \uc815\uae30\uc801 \ubaa8\ub2c8\ud130\ub9c1\uc744 \ubc1b\ub294 \ubc29\uc2dd\uc774\uc5c8\ub2e4. \ubaa8\ub2c8\ud130\ub9c1\uc740 1~3\uac1c\uc6d4 \uac04\uaca9\uc73c\ub85c \ubc14\uc774\ub7ec\uc2a4 \ud45c\uc9c0\uc790\uc640 \uac04\uae30\ub2a5 \uac80\uc0ac\ub97c \ud3ec\ud568\ud588\ub2e4.<\/p>\n<p>\uc608\ubc29 \ubbf8\uc2dc\ud589\uad70(166\uba85)\uc5d0\uc11c \uc7ac\ud65c\uc131\ud654\ub294 13\uba85(7.8%) \ubc1c\uc0dd\ud588\uace0, \uc774\ub4e4 \uc911 \uc911\uc99d \uac04\uc5fc\uacfc \uac04 \uad00\ub828 \uc0ac\ub9dd \uc0ac\ub840\ub294 \ubaa8\ub450 \uc608\ubc29 \ubbf8\uc2dc\ud589\uad70\uc5d0\uc11c \ud655\uc778\ub410\ub2e4. \uc5f0\uad6c\ud300\uc740 \uc7ac\ubc1c\u00b7\ubd88\uc751 \ubcd1\uae30\uc5d0\uc11c \uce58\ub8cc\ub97c \uc2dc\uc791\ud55c \ud658\uc790\uc640 \uae30\uc800 anti-HBs\uac00 100 IU\/L \ubbf8\ub9cc\uc778 \ud658\uc790\uc5d0\uc11c \uc7ac\ud65c\uc131\ud654 \uc704\ud5d8\uc774 \uc720\uc758\ud558\uac8c \ub192\ub2e4\ub294 \uc810\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n<p>\ub9ac\uc2a4\ud06c \uc778\uc790 \ub450 \uac00\uc9c0\ub97c \uacb0\ud569\ud574 \ud658\uc790\ub97c 4\uac1c \uad70\uc73c\ub85c \uce35\ud654\ud55c \uacb0\uacfc, anti-HBs \u2265100 IU\/L\uc774\uace0 1\ucc28 \uce58\ub8cc\uad70\uc778 \uc800\uc704\ud5d8\uad70\uc5d0\uc11c\ub294 \uc7ac\ud65c\uc131\ud654\uac00 \ud55c \uac74\ub3c4 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\ub2e4. \ubc18\uba74 anti-HBs <100 IU\/L\uc774\uba74\uc11c \uc7ac\ubc1c\u00b7\ubd88\uc751 \ub2e8\uacc4\uc5d0\uc11c anti-CD38\uc744 \uc2dc\uc791\ud55c \uace0\uc704\ud5d8\uad70\uc5d0\uc11c\ub294 \ub2e8\uae30\uac04(\uc911\uc559 10.6\uac1c\uc6d4) \ub0b4 \uc57d 19.6%\uc758 \uc7ac\ud65c\uc131\ud654 \ubc1c\uc0dd\ub960\uc744 \ubcf4\uc600\uace0, \uc7a5\uae30 \ucd94\uc815(24\uac1c\uc6d4)\uc5d0\uc11c\ub294 \uc57d 40%\uc5d0 \ub2ec\ud560 \uac00\ub2a5\uc131\uc774 \uc81c\uc2dc\ub410\ub2e4.<\/p>\n<h2>\ubd84\uc11d \ubc0f \uc758\ubbf8<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 \ub3d9\uc77c\ud55c anti-CD38 \uce58\ub8cc\ub97c \ubc1b\ub354\ub77c\ub3c4 \ud658\uc790\ubcc4 \uba74\uc5ed \uc0c1\ud0dc(anti-HBs \uc218\uce58)\uc640 \uce58\ub8cc \uc774\ub825(1\ucc28 vs \uc7ac\ubc1c\u00b7\ubd88\uc751)\uc5d0 \ub530\ub77c \uc7ac\ud65c\uc131\ud654 \uc704\ud5d8\uc774 \ud06c\uac8c \ub2ec\ub77c\uc9c8 \uc218 \uc788\uc74c\uc744 \uc218\uce58\ub85c \ubcf4\uc5ec\uc900 \uccab \uc2e4\uc0ac\uc6a9 \ucf54\ud638\ud2b8 \ubd84\uc11d\uc774\ub2e4. \ud2b9\ud788 \uae30\uc874 EASL \ubd84\ub958 \uae30\uc900\uc0c1 \u2018\uc911\ub4f1\ub3c4 \uc704\ud5d8(1~10%)\u2019\uc5d0 \ud574\ub2f9\ud558\ub294 \uadf8\ub8f9\uc5d0\uc11c\ub3c4 \uc138\ubd84\ud654\ud558\uba74 \uc2e4\uc9c8\uc801 \uace0\uc704\ud5d8 \ud558\uc704\uad70\uc774 \uc874\uc7ac\ud574, \ud1b5\uc0c1\uc801 \ubd84\ub958\ub85c\ub294 \uc608\ubc29 \ub300\uc0c1\uc5d0\uc11c \ub204\ub77d\ub420 \uac00\ub2a5\uc131\uc774 \ub4dc\ub7ec\ub0ac\ub2e4.<\/p>\n<p>\uc784\uc0c1\uc801 \ud568\uc758\ub294 \ub450 \uac00\uc9c0\ub2e4. \uccab\uc9f8, anti-HBs \uce21\uc815(\uc815\ub7c9)\uacfc \ubcd1\uae30 \uc815\ubcf4\ub97c \uc870\ud569\ud55c \ub9ac\uc2a4\ud06c \uce35\ud654\uac00 \uc2e4\uc81c \uc9c4\ub8cc\uc5d0\uc11c \uc7ac\ud65c\uc131\ud654 \uace0\uc704\ud5d8\uad70\uc744 \uc2dd\ubcc4\ud558\ub294 \ub370 \uc720\uc6a9\ud558\ub2e4. \ub458\uc9f8, \uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c \ud22c\uc5ec\ub294 \uace0\uc704\ud5d8\uad70\uc5d0\uc11c \uc911\uc99d \uac04\uc5fc\uacfc \uac04 \uad00\ub828 \uc0ac\ub9dd\uc744 \uc904\uc77c \uc7a0\uc7ac\ub825\uc774 \uc788\uc73c\uba70, \uc18c\uc218\uc5d0\uc11c \uad00\ucc30\ub41c \uc644\uc804 \uc608\ubc29 \ud6a8\uacfc(\uc5f0\uad6c \ub0b4 14\uba85 \ubb34\uc0ac\ub840)\ub294 \uc784\uc0c1\uc801 \uace0\ub824\ub97c \uc815\ub2f9\ud654\ud55c\ub2e4.<\/p>\n<p>\ub2e4\ub9cc \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5\uc801 \uc124\uacc4\uc640 \uc608\ubc29\uad70 \ud45c\ubcf8 \ud06c\uae30\uac00 \uc791\ub2e4\ub294 \uc810\uc740 \ud55c\uacc4\ub85c \ub0a8\uc544 \ud5a5\ud6c4 \ub2e4\uae30\uad00\u00b7\uc804\ud5a5\uc801 \uc5f0\uad6c\ub97c \ud1b5\ud55c \uc804\ub7b5 \uac80\uc99d\uc774 \ud544\uc694\ud558\ub2e4. \uc5f0\uad6c\uc9c4\ub3c4 \uc911\ub4f1\uc704\ud5d8\uad70\uc5d0\uc11c \uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4 \ud22c\uc5ec\uc640 \uac15\ud654 \ubaa8\ub2c8\ud130\ub9c1 \uc911 \uc5b4\ub290 \uc804\ub7b5\uc774 \ub354 \uc6b0\uc218\ud55c\uc9c0 \ube44\uad50\ud558\ub294 \ucd94\uac00 \uc5f0\uad6c\ub97c \uacfc\uc81c\ub85c \uc81c\uc2dc\ud558\uace0 \uc788\ub2e4.<\/p>\n<h2>\ube44\uad50 \ubc0f \ub370\uc774\ud130<\/h2>\n<figure>\n<table>\n<thead>\n<tr>\n<th>\uad70<\/th>\n<th>\ud658\uc790\uc218<\/th>\n<th>\uc7ac\ud65c\uc131\ud654\uc728(\uc911\uc559 \uad00\ucc30)<\/th>\n<th>24\uac1c\uc6d4 \ub204\uc801\ucd94\uc815<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\uc804\uccb4 \uacfc\uac70 \ub178\ucd9c\uc790<\/td>\n<td>180<\/td>\n<td>\u2014<\/td>\n<td>\u2014<\/td>\n<\/tr>\n<tr>\n<td>\uc608\ubc29 \ud22c\uc5ec\uad70<\/td>\n<td>14<\/td>\n<td>0.0%<\/td>\n<td>\uc790\ub8cc \ubd80\uc871<\/td>\n<\/tr>\n<tr>\n<td>\uc608\ubc29 \ubbf8\uc2dc\ud589\uad70<\/td>\n<td>166<\/td>\n<td>7.8% (13\/166)<\/td>\n<td>\u2014<\/td>\n<\/tr>\n<tr>\n<td>\uace0\uc704\ud5d8(anti-HBs&lt;100 + \uc7ac\ubc1c\/\ubd88\uc751)<\/td>\n<td>\ud574\ub2f9 \uc11c\ube0c\uadf8\ub8f9<\/td>\n<td>19.6% (\uc911\uc559 10.6\uac1c\uc6d4)<\/td>\n<td>\uc57d 40% \ucd94\uc815<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\uc704 \ud45c\ub294 \uc5f0\uad6c\uc5d0\uc11c \ubcf4\uace0\ub41c \ud575\uc2ec \uc218\uce58\ub97c \ube44\uad50\ud55c \uac83\uc774\ub2e4. \uc608\ubc29\uad70\uc758 \ud45c\ubcf8\uc774 \uc791\uc544 \uc7a5\uae30 \ucd94\uc815\uce58\ub294 \uc81c\ud55c\uc801\uc774\uba70, \uace0\uc704\ud5d8\uad70\uc758 24\uac1c\uc6d4 \ub204\uc801\ucd94\uc815\uc740 \ucd94\uc815 \ubaa8\ub378\uc5d0 \uae30\ubc18\ud55c \uac12\uc774\ub2e4. \uc22b\uc790\ub294 \uad00\ucc30\uae30\uac04\uacfc \ud45c\ubcf8\uad6c\uc131\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9c8 \uc218 \uc788\uc73c\ubbc0\ub85c \ud574\uc11d \uc2dc \uc8fc\uc758\uac00 \ud544\uc694\ud558\ub2e4.<\/p>\n<h2>\ubc18\uc751 \ubc0f \uc778\uc6a9<\/h2>\n<p>\uc5f0\uad6c \uc81c1\uc800\uc790 \ud0c1\uad8c\uc6a9 \uc784\uc0c1\uac15\uc0ac\ub294 \uc5f0\uad6c \uacb0\uacfc\uc758 \uc784\uc0c1\uc801 \uc801\uc6a9 \uac00\ub2a5\uc131\uc744 \uac15\uc870\ud558\uba70 \uc9c4\ub8cc\ud604\uc7a5\uc5d0\uc11c\uc758 \uc989\uc2dc \ud65c\uc6a9 \uac00\ub2a5\uc131\uc744 \uc5b8\uae09\ud588\ub2e4. \uadf8\ub294 \ud658\uc790 \ud2b9\uc131 \uae30\ubc18\uc758 \uc704\ud5d8\ub3c4 \ubd84\ub958\uac00 \uc2e4\uc81c \uce58\ub8cc \uacb0\uc815\uc744 \ub3d5\ub294\ub2e4\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;anti-HBs \uc218\uce58\uc640 \uce58\ub8cc \uc774\ub825\uc744 \ubc18\uc601\ud55c \uc704\ud5d8\ub3c4 \ubd84\ub958\ub294 \uc2e4\uc81c \uc9c4\ub8cc \ud604\uc7a5\uc5d0\uc11c \ubc14\ub85c \uc801\uc6a9 \uac00\ub2a5\ud558\ub2e4.&#8221;<\/p>\n<p><cite>\ud0c1\uad8c\uc6a9 \uc784\uc0c1\uac15\uc0ac(\uc81c1\uc800\uc790)<\/cite><\/p><\/blockquote>\n<p>\uc131\ud544\uc218 \uad50\uc218\ub294 \uc774\ubc88 \uc5f0\uad6c\uac00 \uae30\uc874\uc758 \uc77c\uad04\uc801 \uc704\ud5d8 \ubd84\ub958\ub97c \ub118\uc5b4 \uace0\uc704\ud5d8\uad70\uc744 \ucc98\uc74c\uc73c\ub85c \uc81c\uc2dc\ud588\ub2e4\ub294 \uc810\uc744 \uc758\ubbf8 \uc788\ub294 \uc131\uacfc\ub85c \ud3c9\uac00\ud588\ub2e4. \uadf8\ub294 \uc120\ubcc4\uc801 \uc608\ubc29\uc804\ub7b5\uc774 \uc911\ub300\ud55c \ud569\ubcd1\uc99d\uc744 \uc904\uc77c \uc218 \uc788\ub2e4\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n<blockquote>\n<p>&#8220;\uc120\ubcc4\uc801 \uc608\ubc29 \ud56d\ubc14\uc774\ub7ec\uc2a4 \uce58\ub8cc \uc804\ub7b5\uc744 \ud1b5\ud574 \uac04\ubd80\uc804\uacfc \uc0ac\ub9dd\uc744 \uc608\ubc29\ud560 \uc218 \uc788\ub2e4\ub294 \uc784\uc0c1\uc801 \uadfc\uac70\ub97c \uc81c\uc2dc\ud588\ub2e4.&#8221;<\/p>\n<p><cite>\uc131\ud544\uc218 \uad50\uc218(\uad50\uc2e0\uc800\uc790)<\/cite><\/p><\/blockquote>\n<p>\ud559\uacc4\uc640 \uc784\uc0c1\uc758 \ubc18\uc751\uc740 \ud5a5\ud6c4 \uac00\uc774\ub4dc\ub77c\uc778 \ubc18\uc601 \uc5ec\ubd80\uc640 \ucd94\uac00 \ub2e4\uae30\uad00 \uc5f0\uad6c\uc758 \uacb0\uacfc\uc5d0 \uc8fc\ubaa9\ud558\ub294 \ubd84\uc704\uae30\ub2e4. \uc5f0\uad6c\uc9c4\uc758 \uc81c\uc548\uc774 \uc784\uc0c1\uc9c0\uce68\uc5d0 \ubc18\uc601\ub418\ub824\uba74 \ub354 \ud070 \uaddc\ubaa8\uc640 \uc804\ud5a5\uc801 \uc99d\uac70\uac00 \uc694\uad6c\ub41c\ub2e4.<\/p>\n<aside>\n<details>\n<summary>\uc6a9\uc5b4\/\ubc29\ubc95\ub860<\/summary>\n<p>anti-CD38 \ud56d\uccb4: \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \uce58\ub8cc\uc5d0 \uc0ac\uc6a9\ub418\ub294 \ud45c\uc801 \ud56d\uccb4\ub85c, \uc885\uc591\uc138\ud3ec\ubfd0 \uc544\ub2c8\ub77c \uc815\uc0c1 \uba74\uc5ed\uc138\ud3ec\uc5d0\ub3c4 \uc601\ud5a5\uc744 \uc904 \uc218 \uc788\ub2e4. anti-HBc \uc591\uc131\u00b7HBsAg \uc74c\uc131: \uacfc\uac70\uc5d0 HBV\uc5d0 \ub178\ucd9c\ub418\uc5c8\uc73c\ub098 \ud45c\uba74\ud56d\uc6d0\uc740 \uc74c\uc131\uc778 \uc0c1\ud0dc\ub85c \uc7a0\ubcf5 \uac10\uc5fc \uac00\ub2a5\uc131\uc774 \uc788\ub2e4. anti-HBs\ub294 \ud45c\uba74\ud56d\uccb4\ub85c \uc218\uce58\uac00 \ub192\uc744\uc218\ub85d \uccb4\ub0b4 HBV\uc5d0 \ub300\ud55c \uba74\uc5ed \ubc29\uc5b4\uac00 \uac15\ud558\ub2e4\ub294 \ub73b\uc774\ub2e4. \uc7ac\ud65c\uc131\ud654\ub294 \ud608\uc911 HBV DNA\uac00 \uac80\ucd9c\ub418\uac70\ub098 HBsAg\uac00 \uc7ac\ucd9c\ud604\ud558\ub294 \uacbd\uc6b0\ub97c \ud3ec\ud568\ud558\uba70, \uc911\uc99d \uac04\uc5fc\u00b7\uac04\ubd80\uc804\u00b7\uc0ac\ub9dd\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub2e4. \ubcf8 \uc5f0\uad6c\ub294 \ud6c4\ud5a5\uc801 \ucf54\ud638\ud2b8 \uc124\uacc4\ub85c, \uad00\ucc30\uc801 \ub370\uc774\ud130 \ud574\uc11d \uc2dc \uc120\ud0dd\ud3b8\ud5a5\uacfc \ud63c\ub780\uc694\uc778\uc744 \uace0\ub824\ud574\uc57c \ud55c\ub2e4.<\/p>\n<\/details>\n<\/aside>\n<h2>\ubd88\ud655\uc2e4\ud55c \ubd80\ubd84<\/h2>\n<ul>\n<li>\uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c\uc758 \uc7a5\uae30\uc801 \uc548\uc804\uc131\u00b7\ud6a8\uc6a9\uc131: \ubcf8 \uc5f0\uad6c\uc758 \uc608\ubc29\uad70 \ud45c\ubcf8\uc774 \uc791\uc544 \uc7a5\uae30\uac04 \ud6a8\uacfc\uc640 \ubd80\uc791\uc6a9 \ud504\ub85c\ud30c\uc77c\uc740 \ucd94\uac00 \ud655\uc778\uc774 \ud544\uc694\ud558\ub2e4.<\/li>\n<li>\uc911\ub4f1\uc704\ud5d8\uad70\uc758 \ucd5c\uc801 \uc804\ub7b5: \uc608\ubc29\ud22c\uc5ec\uc640 \uac15\ud654 \ubaa8\ub2c8\ud130\ub9c1 \uc911 \uc5b4\ub290 \ucabd\uc774 \ube44\uc6a9\ud6a8\uc728\uc801\u00b7\uc784\uc0c1\uc801\uc73c\ub85c \uc6b0\uc218\ud55c\uc9c0 \ube44\uad50 \ub370\uc774\ud130\ub294 \uc544\uc9c1 \uc5c6\ub2e4.<\/li>\n<li>\uc678\ubd80 \ud0c0\uae30\uad00 \uc77c\ubc18\ud654 \uac00\ub2a5\uc131: \ub2e8\uc77c\uae30\uad00 \ud6c4\ud5a5\uc801 \ucf54\ud638\ud2b8 \uacb0\uacfc\ub85c, \ub2e4\ub978 \uc778\uad6c\uc9d1\ub2e8\u00b7\uce58\ub8cc \ud658\uacbd\uc5d0\uc11c \ub3d9\uc77c\ud55c \uc704\ud5d8\ub3c4 \ubd84\ud3ec\uac00 \uc7ac\ud604\ub418\ub294\uc9c0\ub294 \ubbf8\ud655\uc778\uc774\ub2e4.<\/li>\n<\/ul>\n<h2>\ucd1d\ud3c9<\/h2>\n<p>\uc774\ubc88 \uc5f0\uad6c\ub294 anti-CD38 \uce58\ub8cc \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ud658\uc790\uc5d0\uc11c anti-HBs \uc815\ub7c9\uacfc \uce58\ub8cc \ubcd1\uae30\ub97c \uacb0\ud569\ud55c \ub9ac\uc2a4\ud06c \uce35\ud654\uac00 \uc7ac\ud65c\uc131\ud654 \uc704\ud5d8\uc744 \uc2dd\ubcc4\ud558\ub294 \ub370 \uc2e4\ud6a8\uc131 \uc788\ub2e4\ub294 \uc810\uc744 \ucc98\uc74c\uc73c\ub85c \uc2e4\uc0ac\uc6a9 \ub370\uc774\ud130\ub85c \uc81c\uc2dc\ud588\ub2e4. \ud2b9\ud788 \uae30\uc874 \uac00\uc774\ub4dc\ub77c\uc778\uc758 \uc911\ub4f1\ub3c4 \uc704\ud5d8 \ubd84\ub958 \ud558\uc5d0\uc11c\ub3c4 \uc784\uc0c1\uc801\uc73c\ub85c \uace0\uc704\ud5d8\uc5d0 \ud574\ub2f9\ud558\ub294 \ud558\uc704\uad70\uc774 \uc874\uc7ac\ud568\uc744 \ubcf4\uc5ec, \uc77c\ub960\uc801 \uad8c\uace0\uc758 \uc0ac\uac01\uc9c0\ub300\ub97c \uc9c0\uc801\ud588\ub2e4.<\/p>\n<p>\uc784\uc0c1\uc801 \uc801\uc6a9 \uce21\uba74\uc5d0\uc11c anti-HBs \uc218\uce58 \uce21\uc815\uacfc \ubcd1\uae30 \uae30\ubc18 \uc120\ubcc4\uc744 \ud1b5\ud574 \uace0\uc704\ud5d8 \ud658\uc790\uc5d0 \ub300\ud574 \uc120\ubcc4\uc801 \uc608\ubc29 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c \ud22c\uc5ec\ub97c \uace0\ub824\ud560 \uadfc\uac70\uac00 \ub9c8\ub828\ub418\uc5c8\ub2e4. \ub2e4\ub9cc \uadfc\uac70\ub97c \uac15\ud558\uac8c \ub9cc\ub4e4\uae30 \uc704\ud574\uc11c\ub294 \ub2e4\uae30\uad00\u00b7\uc804\ud5a5\uc801 \uc5f0\uad6c\ub85c \uc608\ubc29 \uc804\ub7b5\uc758 \ube44\uc6a9\ud6a8\uacfc\uc131\uacfc \uc7a5\uae30 \uc548\uc804\uc131\uc744 \uac80\uc99d\ud558\ub294 \uac83\uc774 \ub2e4\uc74c \ub2e8\uacc4\ub2e4.<\/p>\n<h2>\ucd9c\ucc98<\/h2>\n<ul>\n<li><a href=\"http:\/\/www.whosaeng.com\/168699\" target=\"_blank\" rel=\"noopener\">\ud6c4\uc0dd\uc2e0\ubcf4<\/a> (\uc5b8\ub860)<\/li>\n<li><a href=\"https:\/\/www.journalofhepatology.org\" target=\"_blank\" rel=\"noopener\">Journal of Hepatology<\/a> (\ud559\uc220\uc9c0, \ud53c\uc5b4\ub9ac\ubdf0)<\/li>\n<\/ul>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\ud575\uc2ec \uc694\uc57d \uac00\ud1a8\ub9ad\ub300 \uc11c\uc6b8\uc131\ubaa8\ubcd1\uc6d0 \uc131\ud544\uc218 \uad50\uc218\ud300(\uc81c1\uc800\uc790 \ud0c1\uad8c\uc6a9 \uc784\uc0c1\uac15\uc0ac)\uc740 2015\ub144~2025\ub144 anti-CD38 \ud56d\uccb4 \uce58\ub8cc\ub97c \ubc1b\uc740 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ud658\uc790 \uc911 \uacfc\uac70 B\ud615\uac04\uc5fc \ub178\ucd9c\uc790(anti-HBc \uc591\uc131, HBsAg \uc74c\uc131) 180\uba85\uc744 \ud6c4\ud5a5\uc801\uc73c\ub85c \ubd84\uc11d\ud574, \uc784\uc0c1\uc801\uc73c\ub85c \uc758\ubbf8 \uc788\ub294 \uc7ac\ud65c\uc131\ud654 \uace0\uc704\ud5d8 \ud558\uc704\uad70\uc744 \uaddc\uba85\ud588\ub2e4. \ucd94\uc801 \uc911\uc559\uac12\uc740 14.5\uac1c\uc6d4\uc774\uba70, \uc608\ubc29\uc801 \ud56d\ubc14\uc774\ub7ec\uc2a4\uc81c\ub97c \ud22c\uc5ec\ud55c 14\uba85\uc5d0\uc11c\ub294 \uc7ac\ud65c\uc131\ud654\uac00 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\ub2e4. \uc608\ubc29 \ubbf8\uc2dc\ud589 166\uba85\uc5d0\uc11c\ub294 13\uba85(7.8%)\uc5d0\uc11c \uc7ac\ud65c\uc131\ud654\uac00 \ubc1c\uc0dd\ud588\uace0, anti-HBs \uc218\uce58\uc640 \ubcd1\uae30(\uc7ac\ubc1c\u00b7\ubd88\uc751)\uac00 \ud575\uc2ec \uc704\ud5d8\uc778\uc790\ub85c \ud655\uc778\ub410\ub2e4. \uc800\ud56d\uad70\uc744 &#8230; <a title=\"CD38 \ud56d\uccb4 \uce58\ub8cc \ubc1b\uc740 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ub9de\ucda4\ud615 \uc608\ubc29 \uc804\ub7b5 \uc81c\uc2dc &#8211; \ud6c4\uc0dd\uc2e0\ubcf4\" class=\"read-more\" href=\"https:\/\/readtrends.com\/ko\/cd38-hepatitis-b-reactivation-myeloma\/\" aria-label=\"CD38 \ud56d\uccb4 \uce58\ub8cc \ubc1b\uc740 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ub9de\ucda4\ud615 \uc608\ubc29 \uc804\ub7b5 \uc81c\uc2dc &#8211; \ud6c4\uc0dd\uc2e0\ubcf4\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":9884,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_title":"CD38 \ud56d\uccb4 \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ub9de\ucda4 \uc608\ubc29\uc804\ub7b5 \uc81c\uc2dc - \ud6c4\uc0dd\uc2e0\ubcf4","rank_math_description":"\uc11c\uc6b8\uc131\ubaa8\ubcd1\uc6d0 \uc5f0\uad6c\ud300\uc774 anti-CD38 \uce58\ub8cc \ub2e4\ubc1c\uc131\uace8\uc218\uc885 \ud658\uc790 180\uba85 \ubd84\uc11d\uc5d0\uc11c anti-HBs <100 IU\/L\uc640 \uc7ac\ubc1c\u00b7\ubd88\uc751 \ubcd1\uae30\uac00 B\ud615\uac04\uc5fc \uc7ac\ud65c\uc131\ud654 \uace0\uc704\ud5d8\uc784\uc744 \uaddc\uba85\ud588\ub2e4. \uace0\uc704\ud5d8\uad70\uc5d0\uc11c \uc120\ubcc4\uc801 \uc608\ubc29\uc758 \ud544\uc694\uc131\uc744 \uc81c\uc2dc\ud55c\ub2e4.","rank_math_focus_keyword":"CD38,\ub2e4\ubc1c\uc131\uace8\uc218\uc885,B\ud615\uac04\uc5fc,\uc7ac\ud65c\uc131\ud654,anti-HBs","footnotes":""},"categories":[2],"tags":[],"class_list":["post-9889","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-top-stories"],"_links":{"self":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9889","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/comments?post=9889"}],"version-history":[{"count":0,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/posts\/9889\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media\/9884"}],"wp:attachment":[{"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/media?parent=9889"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/categories?post=9889"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/readtrends.com\/ko\/wp-json\/wp\/v2\/tags?post=9889"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}